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Sapporo, Japan

Sapporo University , also known as 札大 for an abbreviation, is a private university in Sapporo, Japan. It was founded in 1967. Wikipedia.

Olopatadine hydrochloride ophthalmic solution, 0.2% (olopatadine 0.2%) is approved for allergic conjunctivitis when instilled twice-daily. The objective of this study was to evaluate the efficacy and safety of olopatadine 0.2% (instilled twice-daily) versus vehicle and olopatadine 0.1% (instilled 4-times daily) in Japanese patients with allergic conjunctivitis. A multicenter, parallel-group, double-masked, randomized, conjunctival allergen challenge (CAC) study. Patients > or = 18 years of age with histories of allergic conjunctivitis were treated with either olopatadine 0.2% or olopatadine 0.1% in a single eye and the vehicle in the contralateral eye at 1 visit. Overall, 267 patients were enrolled. Olopatadine 0.2% was superior to its vehicle for ocular itching (p < 0.0001 at the time of observation) and marginally superior for total redness (p = 0.0543 at the time of observation). Olopatadine 0.2% was similar to olopatadine 0.1% for ocular itching at the time of observation. No trends were identified through a review of safety parameters. Olopatadine 0.2% (instilled twice-daily) is safe, well tolerated, superior to the vehicle, and similar to olopatadine 0.1% in preventing ocular itching. Olopatadine 0.2%, which can be instilled less often than olopatadine 0.1%, is a useful new option for allergic conjunctivitis in Japanese patients that could potentially result in better treatment compliance. Source

Yoshida F.,Hokkaido University | Yoshida H.,Sapporo University
Environmental Engineering Science | Year: 2010

This article considers how Japan and the EU manage the recycling of consumer appliances and PCs/cellular phones through a review of their current collection and treatment systems for WEEE (waste electronic and electrical equipment), and on the basis of its findings offers recommendations for the improvement of these systems. We hope thereby to provide information that will be helpful for the better management of WEEE in developed countries as well as in our own. On the basis of our findings, we make the following recommendations: (1) that if Japan hopes to increase its collection rate of WEEE, it has to change its system from one where payment is made at the time of disposal to one where payment is made in advance, whereas the EU has to offer both users and recyclers greater incentives to collect more WEEE; (2) that, within the Japanese system, we have to reduce the cost without reducing the quality of recycling, which, because consumers pay at the time of disposal, is too expensive, whereas the EU must restore the former quality of its recycling, which has been allowed to deteriorate because of the pressure to reduce costs; and (3) that Japan and the EU need to set up a common fund that will enable them to cooperate in the collection and treatment of WEEE to oversee the problems occasioned by the practice of cross-border recycling. © 2009, Mary Ann Liebert, Inc. Source

Himemiya T.,Wakkanai Hokusei Gakuen College | Ohsasa K.,Sapporo University | Ohsasa K.,Akita University | Saga T.,Wakkanai Hokusei Gakuen College
Materials Transactions | Year: 2010

A cell-automaton model for a binary eutectic system has been developed. This study examines a Bridgeman-type temperature field with periodic boundary conditions. A stable operating range of lamellar spacings is obtained based on the parameters of the temperature field. The undercooling of the liquid phase ahead of the solid/liquid interface is also estimated in the calculations. The estimated lamellar spacings and undercoolings agree well with the predictions of the Jackson-Hunt model. © 2010 The Japan Institute of Metals. Source

Katayama M.,Sapporo University
AIJ Journal of Technology and Design | Year: 2014

We report on the design aspects and process of the Asia Zone of Sapporo Maruyama Zoo opened in December 2012, and in particular, focusing on the snowy cold region. We accumulated the zoological design perspectives and experiences since the beginning of the Maruyama Zoo restart project started from 2006. The project was advanced through creating a design guidebook for the zoological exhibition that promotes compassion towards animals and anticipation upon meeting them. The ideas of breeding staffs on the design were reflected to draw the characteristic behavior of animals. Source

Kashiwazaki D.,Kashiwaba Neurosurgical Hospital | Yoshimoto T.,Kashiwaba Neurosurgical Hospital | Mikami T.,Hokkaido University | Muraki M.,Sapporo University | And 3 more authors.
Journal of Neurosurgery | Year: 2012

Object. Identification of the risk of rupture and vulnerability of arterial plaque is not yet clearly understood. The aim of this study was to assess the clinical features of the motion of intraplaque contents (MIC) detected by B-mode ultrasonography. The MIC is characterized by the peculiar movement of the intraplaque contents that is not synchronized with the heartbeat; however, the movement of the carotid artery (CA) wall depends on the heartbeat. Methods. From January 2008 to November 2010, 1798 consecutive patients with transient ischemic attacks (TIAs) or acute ischemic stroke underwent CA ultrasonography for the examination of the MIC. Patients with CA stenosis greater than 50% were followed up until they underwent carotid endarterectomy or CA angioplasty and stent placement. If neither of these procedures were used, the patients were followed up at 90 days. Chi-square and Mann-Whitney tests were performed to compare the categorical and continuous demographic data and risk factors. The effect of the MIC on the rate of recurrent cerebral ischemia was examined using Kaplan-Meier and univariate Cox regression analyses. Results. One hundred and fifteen patients had CA stenosis greater than 50%. Among these 115 patients, 58 with a total of 59 CA stenoses had MIC. Twenty-four recurrent ischemic events were associated with MIC, whereas only 6 such events occurred in the absence of MIC. The MIC decreased event-free survival (log-rank test = 15.8, p < 0.001); univariate Cox analysis confirmed that MIC increased the risk of a recurrent ischemic event (HR 5.12, 95% CI 2.08-12.58; p < 0.001). Conclusions. The MIC is one of the findings of vulnerable plaques. The MIC is more useful in predicting the recurrence of TIAs or ischemic events in patients with symptomatic CA stenosis. Source

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