Chuo-ku, Japan

Sapporo City University
Chuo-ku, Japan

Sapporo City University is a public university with campuses in Chuo-ku and Minami-ku, Sapporo, Japan. The predecessor of the school was established in 1991, and it was chartered as a university in 2006 when it merged with a nursing school. Wikipedia.

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Harai M.,Sapporo City University | Mori M.,Sapporo Medical University
Sapporo Medical journal | Year: 2016

There is a growing need to improve health management strategies for the middle-aged generation to ensure their health in future. The aim of this study was to identify specific risk factors for urinary incontinence (UI) in middle-aged women. In 2014, we randomly selected 800 women between 50 and 64 years from the officially-registered resident database of City A in Japan. Each selected individual was sent a self-administered questionnaire targeting 28 factors, including fundamental attributes, health condition, medical history, present illness, exercise habits, and activities. Participants also received the International Consultation on Incontinence Questionnaire-Short Form (ICIQ - SF). Self-reported UI was defined as frequent UI occurring at least once a week. In total, we analyzed the responses of 173 women. Within this cohort, the self-reported prevalence of UI was 34.1%. There were statistically significant associations of UI with walking time and body weight. Our future studies will aim to conduct a follow-up survey to further clarify the risk factors of UI in middle-aged women.

Kishi Y.,Nippon Medical School | Kurosawa H.,Nippon Medical School | Morimura H.,Sapporo City University | Hatta K.,Juntendo University | Thurber S.,Woodlands Center
General Hospital Psychiatry | Year: 2011

Objective: The aim of this study was to examine the attitudes among Japanese nurses together with their perceived need for training in relation to understanding the nature of suicidal behavior and preventive strategies. Methods: The Understanding Suicidal Patients scale together with additional questions reflecting training and the psychiatric treatment of suicide attempters were administered. Results: A total of 323 nurses attended this study. Overall, the nurses thought patients who attempted suicide were not treated well. The nurses who worked in the psychiatric unit or had the experience in psychiatric nursing had more favorable attitudes toward suicidal patients and viewed themselves as having more relevant skill training in dealing with suicidal patients than those who did not. The nurses who worked at emergency care/intensive care unit were less likely to understand suicidal patients, and were less inclined to be sympathetic and to verbally interact with suicidal patients concerning their problems. The nurses who have confidence in the psychiatric care of suicidal patients, confidence in their own skills, and have a need for more training had the more positive attitudes. Conclusions: The results suggest that less favorable attitudes may to some extent be the result of lack of knowledge regarding suicidal patients. Future studies should focus on the evaluation of educational experiences on attitudes and skill acquisition of nurses. © 2011 Elsevier Inc.

Mikami T.,Sapporo Medical University | Mikami T.,Sapporo City University | Miyashita H.,Sapporo Medical University | Takatsuka S.,Sapporo Medical University | And 2 more authors.
Gene | Year: 2012

Toll-like receptors (TLRs) that initiate an innate immune response contain an extracellular leucine rich repeat (LRR) domain and an intracellular Toll IL-receptor (TIR) domain. There are fifteen different TLRs in vertebrates. The LRR domains, which adopt a solenoid structure, usually have higher rates of evolution than do the TIR globular domains. It is important to understand the molecular evolution and functional roles of TLRs from this standpoint. Both pairwise genetic distances and Ka/. Ks's (the ratios between non synonymous and synonymous substitution rates) were compared between the LRR domain and the TIR domain of 366 vertebrate TLRs from 96 species (from fish to primates). In fourteen members (TLRs 1, 2, 3, 4, 5, 6, 7, 8, 9, 11/12, 13, 14, 21, and 22/23) the LRR domains evolved significantly more rapidly than did the corresponding TIR domains. The evolutionary rates of the LRR domains are significantly different among these members; LRR domains from TLR3 and TLR7 from primates to fishes have the lowest rate of evolution. In contrast, the fifteenth member, TLR10, shows no significant differences; its TIR domain is not highly conserved. The present results suggest that TLR10 may have a different function in signaling from those other members and that a higher conservation of TLR3 and TLR7 may reflect a more ancient mechanism and/or structure in the innate immune response system. Gene conversions are suggested to have occurred in platypus TLR6 and TLR10. This study provides new insight about structural and functional diversification of vertebrate TLRs. © 2012 Elsevier B.V.

Matsushima N.,Sapporo Medical University | Miyashita H.,Sapporo Medical University | Mikami T.,Sapporo Medical University | Mikami T.,Sapporo City University | Kuroki Y.,Sapporo Medical University
BMC Microbiology | Year: 2010

Background. Leucine rich repeats (LRRs) are present in over 60,000 proteins that have been identified in viruses, bacteria, archae, and eukaryotes. All known structures of repeated LRRs adopt an arc shape. Most LRRs are 20-30 residues long. All LRRs contain LxxLxLxxNxL, in which "L" is Leu, Ile, Val, or Phe and "N" is Asn, Thr, Ser, or Cys and "x" is any amino acid. Seven classes of LRRs have been identified. However, other LRR classes remains to be characterized. The evolution of LRRs is not well understood. Results. Here we describe a novel LRR domain, or nested repeat observed in 134 proteins from 54 bacterial species. This novel LRR domain has 21 residues with the consensus sequence of LxxLxLxxNxLxxLDLxx(N/L/Q/x)xx or LxxLxCxxNxLxxLDLxx(N/L/x)xx. This LRR domain is characterized by a nested periodicity; it consists of alternating 10- and 11- residues units of LxxLxLxxNx(x/-). We call it "IRREKO" LRR, since the Japanese word for "nested" is "IRREKO". The first unit of the "IRREKO" LRR domain is frequently occupied by an "SDS22- like" LRR with the consensus of LxxLxLxxNxLxxLxxLxxLxx or a "Bacterial" LRR with the consensus of LxxLxLxxNxLxxLPxLPxx. In some proteins an "SDS22-like" LRR intervenes between "IRREKO" LRRs. Conclusion. Proteins having "IRREKO" LRR domain are almost exclusively found in bacteria. It is suggested that IRREKO@LRR evolved from a common ancestor with "SDS22-like" and "Bacterial" classes and that the ancestor of IRREKO@LRR is 10 or 11 residues of LxxLxLxxNx(x/-). The "IRREKO" LRR is predicted to adopt an arc shape with smaller curvature in which -strands are formed on both concave and convex surfaces. © 2010 Matsushima et al; licensee BioMed Central Ltd.

Yabe K.,Sapporo City University | Nakamura T.,Tokyo University of Agriculture
Landscape and Ecological Engineering | Year: 2010

In order to recreate the landscape of Ishikari Mire, an artificial wetland was made in 2000 at a city park in northern Japan. Its flora, plant communities, and hydrochemical conditions were examined in 2005 and compared with those determined in 2001 and with those of nearby intact fens. Management increased water levels by ca. 10 cm from 2002. Neutral pH, high electrical conductivity (EC), and high concentrations of nitrogen and mineral ions were the same as in 2001, but higher than in fens. The wetland was flooded by river water a few times every year. These hydrochemical conditions suit the growth of fen species. Total species increased from 73 (2001) to 105 (2005), whereas annuals and biennials decreased from 20 to 13 and naturalized exotic species from 18 to 15. Five naturalized exotic species that disappeared by 2005 were all mesophytes, and one of two newly found naturalized exotic species was a hygrophyte. Accordingly, the rapid change can be explained by the change of lifeforms in the early stage of secondary succession, and in some parts, by the disappearance of mesophytic plants as wetness increased. During the 6 years, the wetland communities changed toward that of fens because most of the migrated or imported fen species were increasing. Many other fen plants, therefore, would be able to grow in the wetland, while only four fen species had migrated. Accordingly, importation of other fen plants is essential to recreate the whole plant assemblages of mire. © 2010 International Consortium of Landscape and Ecological Engineering and Springer.

Nakamura R.,The University of Okinawa | Togashi T.,Sapporo City University
Pediatric Infectious Disease Journal | Year: 2013

Before the introduction of vaccines, the incidence of bacterial meningitis among children aged 28 days to 5 years was 8.48, Haemophilus influenzae type-b meningitis was 5.65 and Streptococcus pneumoniae meningitis was 1.85 per 100,000 person-years in Hokkaido, Japan. The incidence of bacteremia caused by S. pneumoniae was 60.15 and H. influenzae was 18.80. © 2013 Lippincott Williams &Wilkins.

When compared to the Western countries, unfortunately, the progress toward the eradication of vaccine-preventable diseases in Japan has been relatively slow and hampered by some problems inherent to Japan. Concerning this, I have been working on the vaccine-preventable diseases, that is, measles, influenza, Haemophilus influenzae, and Streptcoccus pneumoniae infections. My first work was to produce monoclonal antibodies against measles virus proteins, and by using these antibodies, I established the immunofluorescent measles virus detection system in tissue samples. I constructed the 'Hokkaido measles-zero strategy' to eliminate measles from Hokkaido prefecture, the northernmost island of Japan, within 5 years since 2001 with very kind efforts of pediatricians in Hokkaido and those who are engaged in political activities. Coworkers and I established the disease entity of influenza-associated encephalopathy. And finally, I worked as a member of some groups that accumulated the basic data on the occurrence of bacterial meningitis in Japan and urged the government to introduce the H. influenzae type b conjugate vaccine and the pediatric 7-valent pneumococcal conjugate vaccine in Japan. I would like to express many thanks to all of my colleagues for their contributions to these achievements. © 2011 Elsevier Ltd.

Mitani A.,Sapporo City University
Proceedings of the 14th International Conference on Engineering and Product Design Education: Design Education for Future Wellbeing, EPDE 2012 | Year: 2012

This paper described outline of the mechatronics class in the Product Design Course of the School of Design, Sapporo City University, Japan. The mechatronics is an essential technology for various industrial products. In the curriculum of product design education, there are few classes regarding mechatronics to realize functions embedded in products, whereas many classes regarding design expressions using computer software. To propose an effective design to the mechatronics-embedded products, the mechatronics lectures should be included in the curriculum of product design education. For the mechatronics class I offered, a printed circuit substrate was developed to study electronic devices and a PIC processor for design expressions. The lecture included PIC assembler programs for LED blink control, feedback from sensors and switches, the driving of servomotor, and the sequential feedback. This class was done by an assignment to produce an actual model for an interaction design with human actions using these skills.

Harai M.,Sapporo City University
[Nihon kōshū eisei zasshi] Japanese journal of public health | Year: 2013

Urination diseases--particularly urinary incontinence (UI)--strongly affect individuals' quality of life (QOL). It is important to maintain overall QOL in societies with an increasing number of long-living elderly people, such as in Japan. Thus, this study aims to clarify the risk factors concerning UI in elderly women. For this study, we obtained the approval of the Ethical Committee of Sapporo Medical University. In October 2010, we randomly selected 1,600 women, aged between 65 and 74 years, from the registry of Sapporo city residents and mailed out a self-administered questionnaire. Our questionnaire consisted of five subsections (24 items in total), including fundamental attributes, health condition, past history, present illness, and the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). The self-reported prevalence of UI was defined as frequent UI being at least once a week. A logistic regression analysis was used to assess the risk factors for UI. Among those who received the questionnaire, 802 women (response rate: 50.1%) returned a completed questionnaire with written informed consent. Their mean age (+/- standard deviation) was 69.8 +/- 2.6 years, and the prevalence of UI was found to be 29.7%. The mean scores (+/- standard deviation) of ICIQ-SF were 1.7 +/- 2.9 for all participating subjects, and 5.55 +/- 2.50 and 0.09 +/- 0.53 for the groups with or without UI, respectively. The results of the multiple logistic regression analysis were as follows: the odds ratio (95% confidence interval) was 1.94 (1.32, 2.85) for a past maximum weight heavier than or equal to 60 kg; 1.98 (1.18, 3.32) for a smoking index more than or equal to 300; 2.54 (1.47, 4.39) for a poor self-perceived health status; 1.62 (1.09, 2.40) for having a past history of bladder diseases; 1.72 (1.11, 2.69) for having a past history of hemorrhoidal disease; and 2.05 (1.36, 3.10) for a history of UI in one's mother. The self-reported prevalence rate of UI was 29.7% in women aged 65-74 years. In the future, we plan to conduct a follow-up survey to further clarify the risk factors of UI that have been implicated in this cross-sectional study.

Mitani A.,Sapporo City University | Matsuo Y.,Hokkaido University
2011 IEEE International Conference on Robotics and Biomimetics, ROBIO 2011 | Year: 2011

We previously showed that microparts can be fed along an asymmetric microfabricated surface using simple planar symmetric vibrations. Microparts move in one direction because they adhere to the microfabricated surface asymmetrically. We developed sawtoothed surfaces with an elevation angle of 20 deg and various pitches of from 10 to 100 micrometer on the surface of silicon wafer material using a dicing saw with a bevel type blade. We also evaluated the movement of sub-millimeter microparts such as 0603 (size, 0.6 x 0.6 x 0.3 mm; weight, 0.3 mg) and 0402 (size, 0.4 x 0.2 x 0.2 mm; weight, 0.1 mg) capacitors. Then we found that there were fabrication errors and cracks on the top of teeth, and they caused variations of contact between fed microparts and feeder surfaces, which affected the feeding stability of microparts. In the present work, we applied the etching process of single crystal silicon to develop higher accurate and uniform asymmetric fabricated surfaces. Using a silicon wafer with a plain orientation of [221], an asymmetric periodic structure is generated on its surface because the etching speed is different between forward and backward of the crystal face. Three types of etched surfaces were obtained by adjusting the etching parameter. The surface profiles of each surface were measured using a scanning electron microscopy (SEM) system. We also examined the tribologic characteristics by the measurements experiments of the angle of friction of microparts. Finally, we conducted feeding experiments of microparts using these surfaces and compared feeding velocity on each surface. © 2011 IEEE.

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