Desuo C.,Guangxi University |
Desuo C.,Sanxia University |
Ronghui L.,Guangxi University |
Ronghui L.,Guangxi Institute of Water Resources Research
Journal of Convergence Information Technology | Year: 2012
Studies on the possible influences of water-replenishing projects on the habitat of fish along Lijiang River basin are conducted through entity physical model and water-sediment mathematical model, together with the help of acoustic fish tracking system (HTI Model 291). Studies show that under certain hydrological regime, typical fingerlings in Lijiang River such as black carp, crucian carp and silver carp have obviously different response to environmental factors such as depth of water, flow velocity, food source, light and noise, which are reflected in the routes, frequencies and scopes of the migration of fish. This experiment shows that, to some extent, the construction of upstream dams have significant impacts on the migration routes and habitat of the fish; besides the hydrological regime and biochemical indicators, environmental noise, light, vibration, water temperature and so on have significant impacts on the escape behavior of experimental fish.
Sun Y.,Shantou University |
Wu X.,Sanxia University |
Xiong G.,Shantou University
Key Engineering Materials | Year: 2013
In order to enhance the seismic behavior of reinforced concrete (RC) columns more efficiently, a thought to strengthen concrete columns by using steel bar/wire mesh mortar (FS) was proposed. An experimental study including five RC square columns strengthened with FS and steel bar mat mortar (S), respectively, under constant axial loading and lateral cyclic loading was carried out. Seismic bearing capacity, ductility, failure modes and hysteretic characteristics of all columns were tested, and the effect of reinforcement ratio and strengthening method to the tested columns was analyzed. The results showed that the energy dissipation capacity of FS strengthened columns was 73% higher than that of the S strengthened column, though the reinforcement ratio of the former was only 3.02% higher than that of the latter. © (2013) Trans Tech Publications, Switzerland.
Liu Z.,Huazhong University of Science and Technology |
Liu Z.,Sanxia University |
Zhu L.,Huazhong University of Science and Technology |
Qin H.,Huazhong University of Science and Technology |
And 4 more authors.
Journal of Huazhong University of Science and Technology - Medical Science | Year: 2011
This study examined the expression of cell adhesion molecule 1 (CADM1) in pancreatic cancer and the possible mechanism. The expression of CADM1 was detected by immunohistochemistry in tissues of pancreatic cancer, pancreatitis, and normal pancreas. The plasmid pcDNA3.1-Hygro(+)/ CADM1 was transfected into PANC-1 cells (a pancreatic cancer cell line). The expression of CADM1 in the transfected cells was determined by RT-PCR and Western blotting. Cell growth was measured by the MTT method and cell apoptosis by flow cytometry. The results showed that CADM1 was weakly expressed in tissues of pancreatic cancer in contrast to its high expression in normal pancreatic and pancreatitis tissues. The expression level of CADM in pancreatic caner was intensely correlated with the differentiation degree, lymph node metastasis and TNM stages. The growth of CADM1-transfected PANC-1 cells was significantly suppressed in vitro by a G 1 cell cycle arrest and apoptosis occurrence. It was concluded that re-expression of CADM1 inhibits the growth of pancreatic cancer cells and induces their apoptosis in vitro. As a tumor suppressor gene, CADM1 plays an important role in the occurrence, progression and metastasis of pancreatic cancer. © Huazhong University of Science and Technology and Springer-Verlag Berlin Heidelberg 2011.
Jiang K.,Sanxia University |
Song X.,Sanxia University |
Dong Z.,Sanxia University
Chinese Journal of Clinical Oncology | Year: 2011
Small molecular inhibitors that selectively target cancer cells instead of normal cells are promising anti-cancer therapeutics. The mammalian target of rapamycin complex 2 (mTORC2) is emerging as a potential target for inhibitors. Recent studies in oncobiology have indicated that the mTORC2 activity is essential for the transformation, as well as the vitality, of a number of cancer cell types, and that the mTORC2 inhibitor has a broad impact on cancer therapy. In the present study, new findings on the biology of mTORC2 signaling are summarized, and future prospects for mTOR-targeted therapy are highlighted.