PubMed | Oita University and a Sanwa Shurui Co.
Type: Journal Article | Journal: Bioscience, biotechnology, and biochemistry | Year: 2016
We examined the effects of GABA on type I collagen gene expression in normal human dermal fibroblasts. Real-time PCR analysis indicated GABA increased the level of type I collagen transcripts, and suppressed the expression of matrix metalloproteinase-1, which is a collagen-degrading enzyme. These results suggest GABA improves the skin elasticity by regulating type I collagen expression.