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Santos, Brazil

Bica O.C.,Santa Cecilia University | Giugliani E.R.J.,Federal University of Rio Grande do Sul
Birth | Year: 2014

Background: Adolescent mothers living with their mothers may be at greater risk of early weaning. This study aims to assess the influence of a breastfeeding promotion strategy directed at adolescent mothers living with their mothers on the prevalence of breastfeeding in the first year of life. Method: A randomized clinical trial with 323 adolescent mothers. Participants were divided into two groups: those who lived with their mothers and those who did not. Participants were randomly assigned to control or intervention groups. Intervention consisted of breastfeeding counseling sessions held at the maternity ward and at home (at 7, 15, 30, 60, and 120 days postpartum). The intervention effect was assessed by comparing survival curves for breastfeeding in the first 12 months of life. Results: The risk of weaning before 12 months of age was significantly lower in the intervention group for adolescent mothers not living with their mothers; whereas the risk was not statistically different between intervention and control groups for those living with their mothers. Conclusions: The positive influence of systematic counseling sessions on the prevalence of breastfeeding in the first year of life was significant for adolescent mothers. Living with their mothers reduced such influence. © 2014, Wiley Periodicals, Inc. Source


Rohde L.E.,Federal University of Rio Grande do Sul | Bertoldi E.G.,Federal University of Rio Grande do Sul | Goldraich L.,Federal University of Rio Grande do Sul | Polanczyk C.A.,Santa Cecilia University
Nature Reviews Cardiology | Year: 2013

Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Management of HF involves accurate diagnosis and implementation of evidence-based treatment strategies. Costs related to the care of patients with HF have increased substantially over the past 2 decades, partly owing to new medications and diagnostic tests, increased rates of hospitalization, implantation of costly novel devices and, as the disease progresses, consideration for heart transplantation, mechanical circulatory support, and end-of-life care. Not surprisingly, HF places a huge burden on health-care systems, and widespread implementation of all potentially beneficial therapies for HF could prove unrealistic for many, if not all, nations. Cost-effectiveness analyses can help to quantify the relationship between clinical outcomes and the economic implications of available therapies. This Review is a critical overview of cost-effectiveness studies on key areas of HF management, involving pharmacological and nonpharmacological clinical therapies, including device-based and surgical therapeutic strategies. © 2013 Macmillan Publishers Limited. Source


Oliveira G.D.,Santa Cecilia University | Marinho M.M.F.,University of Sao Paulo
Zootaxa | Year: 2016

Moenkhausia abyss is herein described from the rio Amazonas basin lowlands. The new species can be distinguished from the congeners by presenting the combination of the following characters: a dark blotch located on the upper caudal-fin lobe and the lower lobe hyaline, 25-29 branched anal-fin rays, humeral spot rectangular, vertically oriented, extending horizontally through two or two and a half scales and located over the third to the fifth lateral line scales, five longitudinal scale rows above the lateral line, predorsal scales arranged in a single not interrupted median row and 30-34 perforated lateral line scales. Brief comments on Moenkhausia megalops are provided. Copyright © 2016 Magnolia Press. Source


Sakuragui M.M.,Federal University of Sao Carlos | Paulino M.G.,Federal University of Sao Carlos | Pereira C.D.S.,Federal University of Sao Paulo | Pereira C.D.S.,Santa Cecilia University | And 3 more authors.
Environmental Pollution | Year: 2013

This study investigated the relationship between contaminant body burden and the oxidative stress status of the gills and livers of two wild fish species in the Furnas Hydroelectric Power Station (HPS) reservoir (Minas Gerais, Brazil). Gills and livers presented similar pathways of metals and organochlorine bioaccumulation. During June, organochlorines were associated with lipid peroxidation (LPO), indicating oxidative stress due to the inhibition of the antioxidant enzymes superoxide dismutase and glutathione peroxidase. In the most polluted areas, metal concentrations in the liver were associated with metallothionein. During December, contaminants in the gills and liver were associated with catalase activity and LPO. Aldrin/dieldrin was the contaminant most associated with oxidative damage in the livers of both species. This integrated approach shed light on the relationship between adverse biological effects and bioaccumulation of contaminants inputted by intensive agricultural practices and proved to be a suitable tool for assessing the environmental quality of man-made reservoirs. © 2013 Elsevier Ltd. All rights reserved. Source


Valadao Vicente S.J.,University of Sao Paulo | Ishimoto E.Y.,University of Sao Paulo | Cruz R.J.,University of Sao Paulo | Seabra Pereira C.D.,Santa Cecilia University | Torres E.A.F.D.S.,University of Sao Paulo
Journal of Agricultural and Food Chemistry | Year: 2011

This study evaluated the acute effect of the administration of coffee brew in the activity of phase II antioxidant enzymes in the hepatic tissue of rats. A single dose of this beverage increased the activity of the enzymes SOD, CAT, and GPx; the maximum increase occurred 1 h after administration (19.1, 22.1, and 25.1%, respectively). These changes were statistically significant (p < 0.05), the response was shown to be dose-dependent (p < 0.05), and the return to basal levels took >4 h from the intervention, suggesting a long-term effect. The total antioxidant capacity of the hepatic tissue also exhibited a peak 1 h after the intervention (6.5%), but the increase was not statistically significant and the response was not dose-dependent due to the low exposure to coffee. These results indicate that coffee increases the activities of antioxidant enzymes, improving protection against oxidative stress. © 2011 American Chemical Society. Source

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