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São Paulo, Brazil

Albuquerque R.P.,Miguel Couto Municipal Hospital | Giordano V.,Miguel Couto Municipal Hospital | Do Amaral N.P.,Miguel Couto Municipal Hospital | Carvalho A.C.P.,Federal University of Rio de Janeiro | Barretto J.M.,Santa Casa da Misericordia
Revista Brasileira de Ortopedia

A rare occurrence of a case of Hoffa fracture pseudarthrosis in an alcoholic patient with genu valgum associated with venous insufficiency who underwent total knee arthroplasty is reported. The literature is reviewed and the main factors for surgical indication of total 63knee arthroplasty after a fracture of the knee are discussed. Total knee arthroplasty was a viable option in a 60-year-old patient with Hoffa fracture pseudarthrosis and comorbidities. Source

Picciani B.L.S.,Federal University of Fluminense | Souza T.T.,Federal University of Fluminense | Santos V.D.C.B.,Federal University of Fluminense | Domingos T.A.,Federal University of Fluminense | And 5 more authors.
Scientific World Journal

Geographic tongue (GT) and fissured tongue (FT) are the more frequent oral lesions in patients with psoriasis. The aims of this study were to compare the prevalence of GT/FT between psoriasis group (PG) and healthy controls (HC) and investigate the correlation between GT/FT and psoriasis severity using the PASI and age of psoriasis onset. Three hundred and forty-eight PG and 348 HC were selected. According to the age of psoriasis onset, the individuals were classified as having early psoriasis and late psoriasis. The severity of vulgaris psoriasis was determined according to PASI. A follow-up was conducted in patients with psoriasis vulgaris (PV) with GT to evaluate the progression of oral and cutaneous lesions. The FT and GT were more frequent in PG than in HC. The incidence of GT was higher in patients with early psoriasis and that of FT in late-psoriasis. There is association between psoriasis intensity and GT; and a higher monthly decrease of PASI score in patients without GT. The presence of GT and FT is higher in PG than in the HC. GT is associated with disease severity and may be a marker of the psoriasis severity. © 2015 Bruna L. S. Picciani et al. Source

Papais-Alvarenga R.M.,Rio de Janeiro State Federal University | Papais-Alvarenga R.M.,Federal University of Rio de Janeiro | Vasconcelos C.C.F.,Rio de Janeiro State Federal University | Vasconcelos C.C.F.,Federal University of Rio de Janeiro | And 42 more authors.

The idiopathic inflammatory demyelinating disease (IIDD) spectrum has been investigated among different populations, and the results have indicated a low relative frequency of neuromyelitis optica (NMO) among multiple sclerosis (MS) cases in whites (1.2%-1.5%), increasing in Mestizos (8%) and Africans (15.4%-27.5%) living in areas of low MS prevalence. South America (SA) was colonized by Europeans from the Iberian Peninsula, and their miscegenation with natives and Africans slaves resulted in significant racial mixing. The current study analyzed the IIDD spectrum in SA after accounting for the ethnic heterogeneity of its population. A cross-sectional multicenter study was performed. Only individuals followed in 2011 with a confirmed diagnosis of IIDD using new diagnostic criteria were considered eligible. Patients' demographic, clinical and laboratory data were collected. In all, 1,917 individuals from 22 MS centers were included (73.7% female, 63.0% white, 28.0% African, 7.0% Mestizo, and 0.2% Asian). The main disease categories and their associated frequencies were MS (76.9%), NMO (11.8%), other NMO syndromes (6.5%), CIS (3.5%), ADEM (1.0%), and acute encephalopathy (0.4%). Females predominated in all main categories. The white ethnicity also predominated, except in NMO. Except in ADEM, the disease onset occurred between 20 and 39 years old, early onset in 8.2% of all cases, and late onset occurred in 8.9%. The long-term morbidity after a mean disease time of 9.28±7.7 years was characterized by mild disability in all categories except in NMO, which was scored as moderate. Disease time among those with MS was positively correlated with the expanded disability status scale (EDSS) score (r=0.374; p=<0.001). This correlation was not observed in people with NMO or those with other NMO spectrum disorders (NMOSDs). Among patients with NMO, 83.2%showed a relapsing-remitting course, and 16.8%showed a monophasic course. The NMO-IgG antibody tested using indirect immunofluorescence (IIF) with a composite substrate of mouse tissues in 200 NMOSD cases was positive in people with NMO (95/162; 58.6%), longitudinally extensive transverse myelitis (10/30; 33.3%) and bilateral or recurrent optic neuritis (8/8; 100%). No association of NMO-IgG antibody positivity was found with gender, age at onset, ethnicity, early or late onset forms, disease course, or long-term severe disability. The relative frequency of NMO among relapsingremitting MS (RRMS) + NMO cases in SA was 14.0%. Despite the high degree of miscegenation found in SA, MS affects three quarters of all patients with IIDD, mainly white young women who share similar clinical characteristics to those in Western populations in the northern hemisphere, with the exception of ethnicity; approximately one-third of all cases occur among non-white individuals. At the last assessment, the majority of RRMS patients showed mild disability, and the risk for secondary progression was significantly superior among those of African ethnicity. NMO comprises 11.8% of all IIDD cases in SA, affecting mostly young African-Brazilian women, evolving with a recurrent course and causing moderate or severe disability in both ethnic groups. The South-North gradient with increasing NMO and non-white individuals from Argentina, Paraguay, Brazil and Venezuela confirmed previous studies showing a higher frequency of NMO among non-white populations. ©2015 Papais-Alvarenga et al. Source

Bialous S.A.,Tobacco Policy International | Presman S.,Santa Casa da Misericordia | Gigliotti A.,Santa Casa da Misericordia | Muggli M.,Mayo Medical School | Hurt R.,Mayo Medical School
Revista Panamericana de Salud Publica/Pan American Journal of Public Health

Objectives. To document the response of the tobacco industry to the regulation of smoking in public places in Brazil starting in 1996. Methods. The Legacy Tobacco Documents Library (legacy.library.ucsf.edu/) and the British American Tobacco (BAT) Company Documents (bat.library.ucsf.edu/) were searched. The following key words were used: Brasil/Brazil; Souza Cruz; fumo passivo, tabagismo passivo/passive smoking; fumo de segunda mão/secondhand smoking; convivência em harmonia/courtesy of choice; along with the names of institutions, politicians, and individuals associated with tobacco control. We also searched the websites of cigarette manufacturers and hospitality industry organizations and businesses, news websites, and online newspapers and magazines. The search was limited to the period from 1995 to 2005. Results. The text of the first law restricting smoking in Brazil (no. 9 294, of 1996) benefited the industry by stating that smokers and nonsmokers could share the same space provided that specific areas were designated as smoking and nonsmoking. As in other countries, the tobacco industry established partnerships with hotel, bar, and restaurant associations to prevent the passing of laws creating 100% smoke-free environments, as recommended by the World Health Organization. However, local state and city laws in major cities and states (such as Rio de Janeiro and São Paulo) have been successful in ensuring the creation of 100% smoke-free places. Conclusions. It is essential that Brazil recognize the damage caused by smoking and revise its federal law regulating smoking in closed environments. The knowledge concerning the strategies employed by the industry may be useful for politicians and health care professionals to prepare arguments opposing measures that can be detrimental to public health. Source

Rivaben J.H.,Santa Casa da Misericordia | Saad Junior R.,Santa Casa da Misericordia | Neto V.D.,Santa Casa da Misericordia | Botter M.,Santa Casa da Misericordia | Goncalves R.,Santa Casa da Misericordia
Revista do Colegio Brasileiro de Cirurgioes

Objective: To evaluate the natural healing of the rat diaphragm that suffered an extensive right penetrating injury. Methods: Animals were submitted to an extensive penetrating injury in right diaphragm. The sample consisted of 40 animals. The variables studied were initial weight, weight 21 days after surgery; healing of the diaphragm, non-healing of the diaphragm, and herniated abdominal contents into the chest. Results: Ten animals were used as controls for weight and 30 animals were operated. Two animals died during the experiment, so 28 animals formed the operated group; healing of the diaphragm occurred in 15 animals (54%), 11 other animals showed diaphragmatic hernia (39%) and in two we observed only diaphragmatic injury without hernia (7%). Among the herniated organs, the liver was found in 100% of animals, followed by the omentum in 77%, small bowel in 62%, colon in 46%, stomach in 31% and spleen in 15%. The control group and the diaphragmatic healing subgroup showed increased weight since the beginning of the study and the 21 days after surgery (p <0.001). The unhealed group showed no change in weight (p = 0.228). Conclusion: there is a predominance of spontaneous healing in the right diaphragm; animals in which there was no healing of the diaphragm did not gain weight, and the liver was the organ present in 100% the diaphragmatic surface in all rats with healed diaphragm or not. © 2014, Colegio Brasileiro de Cirurgioes. All rights reserved. Source

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