Sant Parmanand Hospital

Delhi, India

Sant Parmanand Hospital

Delhi, India

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Only simple, point-of-care, assay formats of the Platellia Dengue NS1 Ag-ELISA would be suitable to identify Dengue virus in Aedes aegypti mosquitoes in dengue-endemic areas lacking sophisticated laboratory infrastructure and trained laboratory personnel. © 2014 Arya and Agarwal; licensee BioMed Central Ltd.

Arya S.C.,Sant Parmanand Hospital | Agarwal N.,Sant Parmanand Hospital | Parikh S.C.,Sant Parmanand Hospital | Agarwal S.,Sant Parmanand Hospital
Sultan Qaboos University Medical Journal | Year: 2011

Objectives: During 2010, there was an increase in dengue virus infections in New Delhi, India compared to 2009. This study was conducted at Sant Parmanand Hospital during this outbreak to determine the utility of a 'Dengue Package', comprising simultaneous detection of dengue non-structural protein 1 (NS1), anti-dengue IgM, anti-dengue IgG and platelet enumeration for early diagnosis, better case management and faster public health response. Methods: Blood samples were tested for Dengue NS1, IgM and IgG using the single-step immunochromatigrahic One-step dengue NS1 Ag and IgG/IgM test, while platelets were enumerated with automatic analyzers yielding results within 1-2 hours. Results: Of the 1,886 patients screened with the 'Dengue Package', 678 and 1208 were NS1-positive and -negative respectively, in different combinations. In 394 cases, NS1 was exclusively positive while 29 were also IgG positive. In 942 cases NS1, IgM and IgG were negative (triple negative). Te platelet counts in the NS1 positives were lower than the NS1 negatives, mean and standard deviation (SD) 116.8±70.2 × 10 9/L: 95% confidence interval (CI) 66.6-74.1 and 167.2±94.0 × 10 9/L, P<0.0001. Platelet counts were <20 × 10 9/L in 20 NS1 antigen-positives and 42 NS1 antigen-negatives. Conclusion: During the 2010 outbreak, swift availability of the 'Dengue Package' assisted patient management, platelet transfusions, implementation of anti-vector measures and public health notifications. Testing for NS1 assisted the diagnosis of an additional 22.4% cases; of these 394 had evidence of primary infection and 29 of secondary infection. The 'Dengue Package' was useful in tackling the rise in suspected cases.

Gupta P.,Sant Parmanand Hospital | Kansal G.,Sant Parmanand Hospital | Srivastav S.,Sant Parmanand Hospital | Agarwal S.,Sant Parmanand Hospital
Journal of Arthroscopy and Joint Surgery | Year: 2016

Background: Acromioclavicular (AC) joint dislocation is a common shoulder injury that affects young adults. The treatment of these injuries depends on dislocation grade, the patient's complaints and time since injury. Materials: Patients with acute AC joint injuries (Rockwood grades III-V) of less than 4 weeks duration were included in the study. We had 10 cases of AC joint injuries, which fulfilled the inclusion criteria. All patients were diagnosed based on history, examination and plain radiographs. Grading was done based on plain radiographs. Patients with grades III-V were selected for TightRope fixation. All 10 patients with AC joint injury underwent arthroscopic AC joint fixation using TightRope. Functional outcome of patients was done using constant shoulder score preoperatively and postoperatively. All patients were followed up for at least one year. We were able to achieve satisfactory reduction in all the patients. Results: Mean constant score at the final follow-up was 92.2 (range 76-97). The mean difference in constant score between operated and normal shoulder was 9.8. On the basis of difference of constant score, 7 patients had excellent results, 2 had good results and 1 had fair result. Conclusion: Arthroscopic fixation of acute AC joint dislocation using the TightRope device is a simple, reproducible, minimal invasive technique that enables a rapid return to activity for the acute injury. © 2016 International Society for Knowledge for Surgeons on Arthroscopy and Arthroplasty.

Arya S.C.,Sant Parmanand Hospital | Agarwal N.,Sant Parmanand Hospital
Travel Medicine and Infectious Disease | Year: 2012

Mandatory visits to immunization centers that offer pre-travel Yellow fever vaccine to prospective travelers would be useful for briefing the basics of the biology of the mosquito responsible for Yellow fever spread. Pre- travel knowledge on the day-time rather the nocturnal biting habit of the mosquitoes of Aedes species would prevent from bites of the mosquitoes responsible for the spread of viruses causing Yellow fever, dengue or Chikungunya infection. © 2012 Elsevier Ltd. All rights reserved.

Malhan S.,Sant Parmanand Hospital
Journal of orthopaedic surgery (Hong Kong) | Year: 2012

To assess outcomes of minimally invasive plate osteosynthesis (MIPO) using a locking compression plate (LCP) for 42 humeral shaft fractures. METHODS. 28 men and 14 women aged 18 to 68 (mean, 34; median, 29) years underwent closed reduction and MIPO using a LCP for type 12-A (n=26) and type 12-B (n=16) humeral shaft fractures. Eight of the patients were aged ≥ 50 years. Patients were followed up monthly until radiological union in at least 3 of the 4 cortices. Functional assessment was based on the Disabilities of Arm, Shoulder and Hand (DASH) score. The mean follow-up period was 25 (range, 14-35) months. The mean DASH score was 35.1 at month 3 and improved to 8.9 at month 6 and 5.2 at year 1. The mean angulation was 4o in the coronal plane and 7o in the sagittal plane. All fractures united after a mean of 14 weeks. Two patients with transverse fractures had delayed union and received bone marrow injections at 12 or 13 weeks; they achieved union at week 20. One patient developed a radial nerve palsy immediately after surgery and underwent surgical exploration through the anterolateral approach. The plate was re-applied, and the nerve recovered in 48 hours with full power in all the muscle groups. MIPO with LCP is a safe and effective technique for fixation of diaphyseal humeral fractures, and results in faster bone union, better cosmesis, and minimal complications.

Singh H.,Sant Parmanand Hospital
Journal of orthopaedic surgery (Hong Kong) | Year: 2012

To compare outcomes in Indian women who underwent total knee arthroplasty (TKA) using the standard Legacy Posterior Stabilised (LPS) versus the gender-specific LPS high-flexion knee prosthesis. 100 women (200 knees) aged 60 to 80 years with an arc of flexion of ≥90o underwent simultaneous sequential TKA for primary osteoarthritis of both knees. They were randomised to receive the standard NexGen LPS prosthesis (n=50) or the gender-specific NexGen LPS High-Flex prosthesis (n=50). Both knees in each patient received the same prosthesis. The resected bone from the posterior femoral condyle was 2 mm greater when the gender-specific prosthesis was used. Patients were followed up at 3, 6, 12, and 24 months. Range of motion, Knee Society score, and Hospital for Special Surgery score were evaluated pre- and post-operatively by a single assessor. The mean follow-up duration was 2.1 (range, 1.6-2.5) years. Respectively for the standard and gender-specific groups, the mean range of motion was 111o and 112o preoperatively and 120o and 123o at the latest follow-up. The gender-specific group gained approximately 3o more in range of motion (p=0.007). The Knee Society score and the Hospital for Special Surgery score between groups were not significantly different pre- and post-operatively. The perceived advantage of a gender-specific prosthesis over a standard prosthesis did not translate into better clinical and functional outcome scores.

PubMed | Sant Parmanand Hospital
Type: Journal Article | Journal: Journal of orthopaedic surgery (Hong Kong) | Year: 2015

To compare early outcome after total knee arthroplasty (TKA) in women with a positive or negative urine culture.128 women underwent bilateral (n=89) or unilateral (n=39) primary TKA. Diabetes mellitus was present in 38%, obesity in 53%, and asymptomatic urinary tract infection (positive urine culture) in 36% of women. Women with a positive or negative urine culture were compared.In the 46 women with a positive urine culture, Escherichia coli (n=29) and Klebsiella (n=17) were grown. Women with a positive or negative urine culture were comparable in terms of the incidence of diabetes (28% vs. 43%, p=0.1), obesity (52% vs. 54%, p=0.87), fever (9% vs. 15%, p=0.32), leucocytosis (28% vs. 17%, p=0.13), and delayed wound healing (0% vs. 1%, p=0.45).Women with or without a positive urine culture had comparable early complication rates following TKA.

PubMed | Sant Parmanand Hospital, F Wz Inc. and University of Aberdeen
Type: Journal Article | Journal: Journal of orthopaedic case reports | Year: 2016

Late diagnoses of orthopedic injuries after epileptic crisis are a matter of concern. The rarity of correlation between seizure and specific trauma incidences such as bilateral anterior shoulder dislocation, may lead to improper estimation of the patients clinical state, wrong treatment and unpleasant complications.We report a rare case of bilateral anterior shoulder dislocation associated with coracoid processes fracture after a seizure episode, in a young lady of 29 years. This is a rare event, however as patient is often disoriented after seizures, frequently this can be missed diagnosis. So this article puts emphasis on possibilities of rare diagnosis, which if treated promptly can lead to early restoration of complete movement.Although it is not a common problem, but one should have a high degree of suspicion and should always opt for further radiological examination if there is any doubt.

PubMed | Sant Parmanand Hospital and University of Delhi
Type: | Journal: Tropical doctor | Year: 2017

A 30-year-old woman presented to our outpatient department with complaints of pain and swelling in bilateral infrapatellar regions and a discharging sinus in the right knee over the duration of one year. Radiographs showed lytic regions in bilateral patellae. Samples sent from material curetted from sinus yielded no organism but histopathology reported granulomatous inflammation. Following a fresh magnetic resonance imaging (MRI) scan that revealed the infrapatellar pad of fat communicating with the patellar lesions, an exploration and evacuation was done. Material sent revealed epithelioid cell granulomas with caseous necrosis consistent with tuberculosis (TB). The patient was put on first line anti-tubercular treatment (ATT) and has responded favourably with healing of sinus and patellar lesions. Bilateral infrapatellar bursitis is not rare. However patellar TB as a cause for OMIT is not a common diagnosis. A bilateral patellar involvement has not been reported in literature to the best of our knowledge.

PubMed | Sant Parmanand Hospital
Type: Journal Article | Journal: Journal of global antimicrobial resistance | Year: 2016

The objective of this study was to investigate the impact of clinical syndrome-wise categorisation of antimicrobials on the antibiotic susceptibility of nosocomial bacteria at a tertiary care hospital in Delhi, India. The susceptibility of 226 nosocomial bacterial isolates collected during 2008-2011 to meropenem, piperacillin/tazobactam, cefepime, tigecycline, amoxicillin/clavulanic acid (AMC), amikacin, ceftriaxone and ciprofloxacin was monitored and was compared with the antibiotic susceptibility profiles of 72 isolates collected during 2002-2007. During 2008-2011, the isolates included 85% Gram-negative isolates and 15% meticillin-sensitive staphylococci. There was no difference in the susceptibility of the isolates between 2002 and 2007 and 2008-2011, except for a significant increase in Escherichia coli isolates susceptible to AMC (from 73% to 100%), amikacin (70-100%) and cefepime (22-86%), in Klebsiella isolates susceptible to ciprofloxacin (from 25% to 80%) and cefepime (45-75%) and in Pseudomonas isolates susceptible to AMC (from 25% to 86%). In conclusion, during the past decade a clinical syndrome-wise categorisation of antimicrobials in frequent usage as well as culture-based categorisation of infections into nosocomial/community-acquired was useful in establishing the generally insignificant change in the susceptibility of nosocomial isolates and an upsurge in the susceptibility of some isolates to a few antimicrobials. Regular updates on drifts in the antimicrobial susceptibility of local isolates and surveillance of nosocomial infections would be valuable for tackling the emergence of antibiotic-resistant bacteria.

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