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Taormina, Italy

Ceresa F.,Ospedali Riuniti Papardo Piemonte Hospital | Calarco G.,Ospedali Riuniti Papardo Piemonte Hospital | Franzi E.,San Vincenzo Hospital | Patane F.,Ospedali Riuniti Papardo Piemonte Hospital
Interactive Cardiovascular and Thoracic Surgery | Year: 2010

Primary cardiac tumors are rarest form of cancer and the lipoma represent about 8% of these tumors. Cowden disease is a rare autosomal dominant disorder, associated to a germline mutation of the PTEN gene, characterized by multiple hamartomas and an increased risk of breast, thyroid and endometrial carcinomas. For the first time, we describe a right atrial lipoma in a patient affected by Cowden syndrome. The patient suffered of some episodes of atrial flutter. The echocardiogram showed a cardiac mass, suggestive of lipoma with cardiac magnetic resonance images. Right atrial mass was completely resected and the histological examination confirmed the diagnosis of lipoma. The patient was discharged from hospital without any complications. © 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved. Source

Marcantoni C.,Cannizzaro Hospital | Castellino S.,San Vincenzo Hospital | Cicchetti T.,Azienda Sanitaria Provinciale | Mallamaci F.,Ospedali Riuniti
Journal of Nephrology | Year: 2011

The education level of women has increased significantly in recent decades. However, although there is a continued positive trend overall, women remain underrepresented (or misrepresented?) in the main fields of science. In Europe the proportion of women in scientific research is growing faster than that of men, but women are more likely than men to choose education, arts and humanities, health and welfare. Moreover, of the total number of women graduating in all faculties (55%), the percentage of women graduating in medicine is 65%-68%, in Europe as in the United States. As far as nephrology is concerned, unpublished data from the Italian Society of Nephrology indicate that female nephrologists make up almost 30% of the total number in the age group between 40 and 55, and this proportion is even higher in the age group younger than 40 years. In comparison with the past, there are some hints that things are going to change, but the path is still a difficult one, much effort is needed and there is a long way ahead. © 2011 Società Italiana di Nefrologia. Source

Calvagna G.M.,San Vincenzo Hospital | Romeo P.,San Vincenzo Hospital | Ceresa F.,Ospedale Papardo | Valsecchi S.,Boston Scientific Italy
PACE - Pacing and Clinical Electrophysiology | Year: 2013

Background Many techniques for the endovascular retrieval of lost or misplaced foreign objects have been developed, and the removal of almost every foreign object has become possible. In this paper, we report our experience in retrieving foreign objects lost during cardiac device implantations or previous extraction procedures. Methods This study was a retrospective analysis of the case records of all patients referred to our institution for transvenous retrieval of intravascular foreign objects. Results Over 10 years, 45 consecutive patients underwent procedures for the retrieval of intravascular foreign objects. These objects were: 25 distal portions of introducer sheaths, 18 pacing lead fragments, one guidewire, and one anchoring sleeve. The majority of fragments were located in the right ventricle and subclavian and caval veins. Some had migrated to the pulmonary artery or more distally. The median dwell time of the fragments was 3 months. Retrieval was most frequently achieved through the femoral veins, and was successful in 42 (93%) procedures. No procedure-related complications occurred in this series. Conclusions In the present single-center experience, the endovascular approach to retrieving intravascular objects lost during cardiac device implantation or previous extraction procedures seemed effective with currently available tools and was associated with no complications. ©2013, The Authors. Journal compilation ©2013 Wiley Periodicals, Inc. Source

Banna G.L.,University of Catania | Collova E.,Hospital of Legnano | Gebbia V.,University of Palermo | Lipari H.,University of Catania | And 6 more authors.
Cancer Treatment Reviews | Year: 2010

The use of oral anticancer drugs has shown a steady increase. Most patients prefer anticancer oral therapy to intravenous treatment primarily for the convenience of a home-based therapy, although they require that the efficacy of oral therapy must be equivalent and toxicity not superior than those expected with the intravenous treatment. A better patient compliance, drug tolerability, convenience and possible better efficacy for oral therapy as compared to intravenous emerge as the major reasons to use oral anticancer agents among oncologists. Inter- and intra-individual pharmacokinetic variations in the bioavailability of oral anticancer drugs may be more relevant than for intravenous agents. Compliance is particularly important for oral therapy because it determines the dose-intensity of the treatment and ultimately treatment efficacy and toxicity. Patient stands as the most important determinant of compliance. Possible measures for an active and safe administration of oral therapy include a careful preliminary medical evaluation and selection of patients based on possible barriers to an adequate compliance, pharmacologic issues, patient-focused education, an improvement of the accessibility to healthcare service, as well as the development of home-care nursing symptom-focused interventions. Current evidences show similar quality of life profile between oral and intravenous treatments, although anticancer oral therapy seems to be more convenient in terms of administration and reduced time lost for work or other activities. Regarding cost-effectiveness, current evidences are in favor of oral therapy, mainly due to reduced need of visits and/or day in hospital for the administration of the drug and/or the management of adverse events. © 2010 Elsevier Ltd. Source

Calvagna G.M.,San Vincenzo Hospital | Evola R.,San Vincenzo Hospital | Scardace G.,Medtronic | Valsecchi S.,Medtronic
PACE - Pacing and Clinical Electrophysiology | Year: 2012

We describe the case of a man with an implantable defibrillator and a dual-coil lead introduced via the right internal jugular vein. Due to pocket infection and lead erosion at the jugular vein, transvenous lead extraction was attempted with a mechanical single-sheath technique. The lead was completely removed without complications with culture and sensitivity results guiding an effective antibiotic therapy. (PACE 2012; 35:e258-e260) ©2011, The Authors. Journal compilation ©2012 Wiley Periodicals, Inc. Source

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