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Culiacan, Mexico

Izrailev F.M.,Autonomous University of Puebla | Makarov N.M.,San Miguel University | Torres-Herrera E.J.,Autonomous University of Puebla
Physica B: Condensed Matter | Year: 2010

The localization length has been derived for one-dimensional bi-layered structures with random perturbations in the refractive indices for each type of layers. Main attention is paid to the comparison between conventional materials and those consisting of mixed right-hand and left-hand materials. It is shown that the localization length is described by the universal expression for both cases. The analytical results are confirmed by numerical simulations. © 2010 Elsevier B.V. All rights reserved. Source

Nieto M.A.,San Miguel University
Annual Review of Cell and Developmental Biology | Year: 2011

The epithelial to mesenchymal transition (EMT) converts epithelial cells into migratory and invasive cells and is a fundamental event in morphogenesis. Although its relevance in the progression of cancer and organ fibrosis had been debated until recently, the EMT is now established as an important step in the metastatic cascade of epithelial tumors. The similarities between pathological and developmental EMTs validate the embryo as the best model to understand the molecular and cellular mechanisms involved in this process, identifying those that are hijacked during the progression of cancer and organ degeneration. Our ever-increasing understanding of how transcription factors regulate the EMT has revealed complex regulatory loops coupled to posttranscriptional and epigenetic regulatory programs. The EMT is now integrated into the systemic activities of whole organisms, establishing links with cell survival, stemness, inflammation, and immunity. In addition, the EMT now constitutes a promising target for the treatment of cancer and organ-degenerative diseases. © 2011 by Annual Reviews. All rights reserved. Source

Baker P.A.,Duke University | Baker P.A.,San Miguel University | Fritz S.C.,University of Nebraska - Lincoln
Quaternary Science Reviews | Year: 2015

This selective review of the Quaternary paleoclimate of the South American summer monsoon (SASM) domain presents viewpoints regarding a range of key issues in the field, many of which are unresolved and some of which are controversial. (1) El Niño-Southern Oscillation variability, while the most important global-scale mode of interannual climate variation, is insufficient to explain most of the variation of tropical South American climate observed in both the instrumental and the paleoclimate records. (2) Significant climate variation in tropical South America occurs on seasonal to orbital (i.e. multi-millennial) time scales as a result of sea-surface temperature (SST) variation and ocean-atmosphere interactions of the tropical Atlantic. (3) Decadal-scale climate variability, linked with this tropical Atlantic variability, has been a persistent characteristic of climate in tropical South America for at least the past half millennium, and likely, far beyond. (4) Centennial-to-millennial climate events in tropical South America were of longer duration and, perhaps, larger amplitude than any observed in the instrumental period, which is little more than a century long in tropical South America. These were superimposed upon both precession-paced insolation changes that caused significant variation in SASM precipitation and eccentricity-paced global glacial boundary conditions that caused significant changes in the tropical South American moisture balance. As a result, river sediment and water discharge increased and decreased across tropical South America, lake levels rose and fell, paleolakes arose and disappeared on the Altiplano, glaciers waxed and waned in the tropical Andes, and the tropical rainforest underwent significant changes in composition and extent.To further evaluate climate forcing over the last glacial cycle (~125ka), we developed a climate forcing model that combines summer insolation forcing and a proxy for North Atlantic SST forcing to reconstruct long-term precipitation variation in the SASM domain. The success of this model reinforces our confidence in assigning causation to observed reconstructions of precipitation. In addition, we propose a critical correction for speleothem stable oxygen isotopic ratios, which are among the most significant of paleoclimate proxies in tropical South America for reconstruction of variation of paleo-precipitation (or SASM intensity). However, it is already well known that any particular δ18O value observed in speleothem carbonate is affected by two processes that have nothing to do with changes in precipitation amount-the influence of temperature on carbonate-water isotopic fractionation in the cave and the influence of changing δ18O of seawater. Quantitatively accounting for both "artifacts" can significantly alter the interpretations of speleothem records. In tropical South America, both adjustments act in the same direction and have the tendency to increase the true amplitude of the paleo-hydrologic signal (but by different amounts in glacial and inter-glacial stages). These corrections have even graver implications for the interpretation of tropical Northern Hemisphere speleothem records (e.g. Chinese speleothems) where the combined adjustments tend to decrease or even eliminate the "true" signal amplitude. © 2015 Elsevier Ltd. Source

Tchatalbachev S.,Justus Liebig University | Ghai R.,Justus Liebig University | Ghai R.,San Miguel University | Hossain H.,Justus Liebig University | Chakraborty T.,Justus Liebig University
BMC Microbiology | Year: 2010

Background. We infected freshly isolated human peripheral monocytes with live bacteria of three clinically important gram-positive bacterial species, Staphylococcus aureus, Streptococcus pneumoniae and Listeria monocytogenes and studied the ensuing early transcriptional response using expression microarrays. Thus the observed response was unbiased by signals originating from other helper and effector cells of the host and was not limited to induction by solitary bacterial constituents. Results. Activation of monocytes was demonstrated by the upregulation of chemokine rather than interleukin genes except for the prominent expression of interleukin 23, marking it as the early lead cytokine. This activation was accompanied by cytoskeleton rearrangement signals and a general anti-oxidative stress and anti-apoptotic reaction. Remarkably, the expression profiles also provide evidence that monocytes participate in the regulation of angiogenesis and endothelial function in response to these pathogens. Conclusion. Regardless of the invasion properties and survival mechanisms of the pathogens used, we found that the early response comprised of a consistent and common response. The common response was hallmarked by the upregulation of interleukin 23, a rather unexpected finding regarding Listeria infection, as this cytokine has been linked primarily to the control of extracellular bacterial dissemination. © 2010 Tchatalbachev et al; licensee BioMed Central Ltd. Source

Martynyuk A.E.,National Autonomous University of Mexico | Martinez-Lopez A.G.,San Miguel University | Rodriguez-Cuevas J.,National Autonomous University of Mexico
Electronics Letters | Year: 2010

An electronically-reconfigurable spiraphase-type element based on a ring slot resonator is analysed. It is demonstrated with numerical simulation and experimental measurements that optimal transformation of the switch impedances is possible in this element. As a result, low loss of 0.38dB is obtained for the one-bit element at the frequency of 11.55GHz. © 2010 The Institution of Engineering and Technology. Source

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