Samsun Chest Diseases and Thoracic Surgery Hospital

Samsun, Turkey

Samsun Chest Diseases and Thoracic Surgery Hospital

Samsun, Turkey
SEARCH FILTERS
Time filter
Source Type

Sengul A.T.,Ondokuz Mayis University | Buyukkkarabacak Y.B.,Ondokuz Mayis University | Altunkaynak B.Z.,Ondokuz Mayis University | Yetim T.D.,Mustafa Kemal University | And 3 more authors.
Acta chirurgica Belgica | Year: 2017

BACKGROUND: In cases of congenital chest wall deformities, it is important to maintain the flexibility of the chest wall after rib cartilage resection. In this study, we aimed to determine the regeneration capability of cartilage and the effects of platelet-rich plasma (PRP) on the regeneration process.METHODS: A total of 16 four-week-old New Zealand rabbits were used in this study. In the 4th-5th right costal cartilages, the perichondrial sheaths were dissected and costal cartilages were excised. Then, the perichondrial sheaths were closed with absorbable material in the sham group (n = 8), and this was done after replacing PRP in the PRP group (n = 8). The left costal cartilages of the animals were used as controls. The volumes of the costal cartilages and their perichondrial sheaths were estimated using Cavalieri's principle. In addition, the mean numerical densities of the chondroblasts and chondrocytes per square millimetre were estimated using unbiased counting frames.RESULTS: In the PRP and sham groups, the volumes of the cartilages and perichondrial sheaths were higher than those of the control group (p < 0.05). The numerical densities of the chondroblasts and chondrocytes increased more in the PRP group than in the sham group (p < 0.05).CONCLUSIONS: Applying PRP after resection may provide better healing and faster regeneration of cartilage.


Ozkaya S.,Bahcesehir University | Dirican A.,Samsun Medicalpark Hospital | Kaya S.O.,Samsun Medicalpark Hospital | Karanfil R.C.,Samsun Medicalpark Hospital | And 3 more authors.
International Journal of COPD | Year: 2014

Maximal inspiratory pressure (MIP) is a marker for assessing the degree of respiratory muscle dysfunction. Muscle dysfunction represents a pathophysiological feature of chronic obstructive pulmonary disease. We aimed to determinate the MIP value in patients with airway obstruction, to evaluate the change in MIP with bronchodilator drug, and to show the relationship between the changes in MIP and disease characteristics. We evaluated 21 patients with airway obstruction at the Department of Pulmonary Medicine, Samsun Medicalpark Hospital, Samsun, Turkey. We performed pulmonary function tests, measurement of MIP values, and reversibility tests with salbutamol. The baseline spirometry results were: mean forced vital capacity (FVC), 3,017±1,020 mL and 75.8%±20.8%; mean forced expiratory volume in 1 second (FEV1), 1,892±701 mL and 59.2%±18.2%; FEV1/FVC, 62.9%±5.5%; peak expiratory flow, 53%±19%. The pre-bronchodilator MIP value was 62.1±36.9 cmH2O. The reversibility test was found to be positive in 61.9% of patients with salbutamol. The absolute change and percentage of change in FEV1 were 318±223 mL and 19.8%±16.7%, respectively. The MIP value was increased by 5.5 cmH2O (8.8%) and was 67.7±30.3 cmH2O after bronchodilation. There was no significant relationship between age, FEV1, reversibility, and change in MIP with bronchodilator. However, the increase in MIP with bronchodilator drug was higher in patients with low body mass index (<25 kg/m2). We noted a 13.1% increase in FVC, a 19.8% increase in FEV1, a 20.2% increase in peak expiratory flow, and an 8.8% increase in MIP with salbutamol. In conclusion; MIP increases with bronchodilator therapy, regardless of changes in lung function, in patients with airway obstruction. The reversibilty test can be used to evaluate change in MIP with salbutamol. © 2014 Ozkaya et al.


Ozkaya S.,Recep Tayyip Erdoğan University | Sengul B.,Samsun Chest Diseases and Thoracic Surgery Hospital | Hamsici S.,Samsun Chest Diseases and Thoracic Surgery Hospital | Findik S.,Ondokuz Mayis University | And 3 more authors.
Multidisciplinary Respiratory Medicine | Year: 2012

Background: Right sided arcus aorta (RSAA) is a rare condition that is usually asymptomatic. Patients may present with exertional dyspnea and chronic cough. A recent article suggested that RSAA should be included in the differential diagnosis of asthma, especially in patients with intractable exertional dyspnea. We aimed to present the clinical, radiologic and spirometric features of thirteen patients with RSAA observed in four years at the Rize Education and Research Hospital and Samsun Chest Diseases and Thoracic Surgery Hospital. Methods: The characteristics of patients with RSAA, including age, gender, symptoms, radiologic and spirometric findings, were retrospectively evaluated. Results: A total of thirteen patients were diagnosed with RSAA. Their ages ranged from 17 to 86 years and the male to female ratio was 11:2. Seven of the patients (54%) were symptomatic. The most common symptoms were exertional dyspnea, dysphagia and chronic cough. Five patients had received treatment for asthma with bronchodilators. Spirometry showed intrathoracic tracheal obstruction in five patients. Conclusions: The RSAA anomaly occurs more frequently than might be estimated from the number of patients who are detected. Patients with intractable exertional dyspnea and chronic cough should be evaluated for the RSAA anomaly by thoracic CT. © 2012 Ozkaya et al.; licensee BioMed Central Ltd.


Ozkaya S.,Recep Tayyip Erdoğan University | Bilgin S.,Samsun Chest Diseases and Thoracic Surgery Hospital | Hamsici S.,Samsun Chest Diseases and Thoracic Surgery Hospital | Findik S.,Ondokuz Mayis University
Respiratory Medicine CME | Year: 2011

The rheumatoid arthritis (RA) is can affect multiple organs and tissues including the lung. Several pleuropulmonary manifestations are associated with rheumatoid arthritis involving the lung parenchyma, pleura, airways, and vasculature. The various pulmonary radiological findings have been defined in patients with RA.In this study, we aimed to retrospectively evaluate of the pulmonary radiologic findings in the five patients with RA.In the present study, pleural effusion, hydropneumothorax, chylothorax, pulmonary micronodular, macronodular and necrobiotic nodular lesions, pleural plagues, ground glass opacity and interstitial lung diseases were defined according to chest radiographs and computed tomography. The most common pulmonary radiologic findings were pulmonary nodules in three of patients, necrobiotic nodule in two of patients, pleural plague in two of patients and pleural effusion in two patients. The one of them had hydropneumothorax. Interstitial lung diseases were defined in two of patients.In conclusion, the pulmonary changes may be accompanied as a systemic component of the RA. If these changes are well recognized, they can help in the diagnosis of the RA. © 2011.


Ozkaya S.,Samsun Medical Park Hospital | Dirican A.,Samsun Medical Park Hospital | Tuna T.,Samsun Chest Diseases and Thoracic Surgery Hospital | Ece F.,Bahcesehir University
BMJ Case Reports | Year: 2013

Right-sided arcus aorta (RSAA) is a rare congenital anomaly that may cause chronic cough and dyspnoea. We aimed to define RSAA as a new syndrome characterised by RSAA, dyspnoea and cough during exercise. RSAA syndrome should be included in the differential diagnosis of asthma. Copyright © 2013 BMJ Publishing Group. All rights reserved.


Ozkaya S.,Bahcesehir University | Dirican A.,Samsun Medical Park Hospital | Tuna T.,Samsun Chest Diseases and Thoracic Surgery Hospital
International Journal of COPD | Year: 2016

Airway obstruction is variable in asthma, while it is progressive and persistent in chronic bronchitis and emphysema.However, some of the patients presenting with symptoms of chronic airway diseases have clinical features of both asthma and COPD.The group with "Asthma-COPD Overlap Syndrome" (ACOS) phenotype was characterized by definitely irreversible airway obstruction accompanied by symptoms and signs of reversibility.In this study, we aimed to classify obstructive airway diseases by clinical, radiological, and pulmonary function tests.Patients at Samsun Medical Park Hospital Chest Diseases outpatient clinic were evaluated between January 2013 and April 2016, and a total of 235 patients were included in this study.Mean age of the patients was 55.3±14.5 (15-88) years, and the male/female ratio was 45/190.The baseline pulmonary function test results of the patients were as follows: mean forced vital capacity (FVC) values 2,825±1,108 (710-6,870) mL and 74.3±22.4 (24-155)%, forced expiratory volume in 1 second (FEV1) values 1,789±774 (480-4,810) mL and 58.1±20.0 (20-130)%, FEV1/FVC values 62.5±6.8 (39-70)%.Reversibility criteria following bronchodilator treatment were present in 107 (45.5%) patients.We specified five subgroups for patients according to their clinical, radiological, and pulmonary test findings, namely Group 1 (asthma), Group 2 (ACOS), Group 3 (chronic bronchitis), and Group 4 (emphysema).Additionally, a group of patients who had clinical and spirometric features of both asthma and chronic bronchitis in association with underlying emphysema (emphysema with chronic bronchitis and emphysema with asthma) was defined as the undifferentiated obstruction (UNDO) group.Number and percentage distribution of patients by groups were 58 (24.7%) in the asthma group, 70 (29.8%) in the ACOS group, 61 (26%) in the chronic bronchitis group, 32 (13.6%) in the emphysema group, and 14 (6%) in the UNDO group.In conclusion, in our study, the types of obstructive airway diseases could be classified based on clinical, radiological, and pulmonary function test findings into five groups, including asthma, ACOS, chronic bronchitis, emphysema, and both asthma and chronic bronchitis in association with underlying emphysema (emphysema with chronic bronchitis and emphysema with asthma) or the so-called undifferentiated obstruction.We suggest that these patient groups can be determined more accurately by studies that evaluate the association between spirometric FEV1, FEV1/FVC values, and reversibility ratios. © 2016 Ozkaya et al.


Tuna T.,Samsun Chest Diseases and Thoracic Surgery Hospital
BMJ case reports | Year: 2013

Sarcoidosis is an idiopathic, chronic granulomatous disease and it can affect almost any organ. In autopsy series, it has been reported that the central nervous system involvement has occurred in 5-16% of the patients with sarcoidosis, while the neurological symptoms have occurred only in 3-9% of them. A 40-year-old female patient was admitted to the hospital with complaints of aphasia, balance disorder and drowsiness. An intracerebral mass was detected on cranial CT scans and neurosarcoidosis was diagnosed with clinical, radiological and histopathological findings.


PubMed | Samsun Chest Diseases and Thoracic Surgery Hospital
Type: | Journal: OncoTargets and therapy | Year: 2013

Computed tomography-guided transthoracic needle aspiration (TTNA) and biopsy (TTNB) is a well established, safe, and rapid method of reaching a definitive diagnosis for most thoracic lesions. The present study aimed to determine the roles of TTNA and TTNB in the diagnosis of pulmonary diseases and to compare the results using these two techniques.TTNB and TTNA were performed in 105 patients admitted to our clinic due to peripheral pulmonary lesions between May 2005 and November 2007. Needle biopsies were performed using 18-gauge Tru-Cut biopsy needles and aspirations was performed using 18-20-22-gauge Chiba needles.Malignant lesions diagnosed by TTNB were non-small cell lung carcinoma (51 patients, 73%), small cell lung carcinoma (nine patients, 13%), malignant tissue (three patients, 5%), lymphoma (two patients, 3%), thymoma (two patients, 3%), plasmacytoma (one patient, 1%), rhabdomyosarcoma (one patient, 1%), and metastasis (one patient, 1%). The malignant lesions diagnosed by TTNA were non-small cell lung carcinoma in eleven patients (92%) and malignant tissue in one patient (8%). Three (100%) of the benign lesions diagnosed by TTNB were granulomas and two (100%) benign lesions diagnosed by TTNA were infarctions. When the diagnostic value of TTNB and TTNA was compared, TTNB was significantly superior. Malignant lesions were identified in 70 (84%) and benign lesions were identified in three (4%) of the 83 patients in the TTNB group. Ten (12%) patients in the TTNB group could not be diagnosed. Malignant lesions were found in 12 (55%) and benign lesions were found in two (9%) of the 22 patients in the TTNA group. Negative results were obtained in eight (36%) patients. The diagnostic sensitivity, specificity, and accuracy of TTNB was calculated to be 92%, 100%, and 93%, respectively (Table 5). The diagnostic sensitivity, specificity, and accuracy of TTNA was 78%, 100%, and 82%, respectively. TTNB had a sensitivity of 92% (70/76) in malignant cases and 100% (3/3) in benign cases, while the sensitivity of TTNA in malignant and benign cases was 75% (3/4) and 67% (2/3), respectively.TTNB is a safe and easy procedure which provides a highly accurate diagnosis of benign and malignant lung lesions without causing a significant increase in complication rates.


PubMed | Samsun Chest Diseases and Thoracic Surgery Hospital
Type: | Journal: International medical case reports journal | Year: 2013

Endobronchial lipoma is a rare neoplasm of the tracheobronchial tree and it may cause irreversible pulmonary damage due to recurrent pneumonia. Rarely, it may mimic bronchial asthma. We present a 53-year-old woman with an endobronchial lipoma, which had been treated as a bronchial asthma for four years. She also had developed recurrent pneumonia three times.


PubMed | Samsun Chest Diseases and Thoracic Surgery Hospital
Type: | Journal: International medical case reports journal | Year: 2013

Lung cancer does not generally produce any symptoms at the early stages and it rapidly metastasizes. Although lung cancer has a potential of metastasis to all organs and tissues, metastasis to the penis from lung cancer is very rare. We present a case with a penile lesion as the first sign of lung cancer.

Loading Samsun Chest Diseases and Thoracic Surgery Hospital collaborators
Loading Samsun Chest Diseases and Thoracic Surgery Hospital collaborators