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Manchester, United Kingdom

Rai S.,Salford Royal Hospital Salford | Madan V.,Salford Royal Hospital Salford | August P.J.,Salford Royal Hospital Salford | Ferguson J.E.,Salford Royal Hospital Salford
British Journal of Dermatology | Year: 2014

Background Favre-Racouchot syndrome (FRS) is both disfiguring and difficult to treat. Available medical and surgical therapies are of variable efficacy. Most treatments do not achieve complete resolution and do not show maintenance of therapeutic response. Objectives To assess the response to a novel two-step treatment using the CO2 laser in patients with FRS. Methods Seven patients with FRS were treated with the CO2 laser in resurfacing mode with manual expression of comedones under infiltrative local anaesthesia. The procedure was completed in one treatment session lasting 30 min and the wound was left to heal by secondary intention. A topical antibiotic was applied to treated areas, which were covered with a nonadherent dressing. All patients were assessed 3 months postoperatively by the operating laser surgeon and a visual assessment of clinical response to treatment in comparison with pretreatment photographs was made. Patient satisfaction was also recorded. Results All patients achieved complete resolution of FRS. The follow-up duration for our cohort ranged from 8 months to 3 years. Two patients required further treatment within a 2-3-year period from initial treatment. Disease relapse was noted over 1 year after the primary treatment; both these cases were smokers and repeat treatment with similar laser parameters maintained reproducible results. Our longest disease-free follow-up duration was 3 years postprimary treatment. The laser surgeons and patients reported high levels of therapeutic benefit and satisfaction with the results. Conclusions This two-step treatment of FRS (CO2 laser resurfacing and manual pressure-induced expression of comedones) is an effective and durable treatment for FRS with an excellent cosmetic outcome. Long-term follow-up beyond 3 years is planned to determine whether later recurrence occurs with this technique. What's already known about this topic? Favre-Racouchot syndrome is a difficult condition to treat effectively and, when treated, maintenance of treatment response remains a challenge. What does this study add? We describe a novel two-step approach in the treatment of Favre-Racouchot syndrome. Our method differs from other methods using CO2 laser as it uses silk touch resurfacing mode and manual extraction of comedones, which results in no apparent visual scarring. This method achieves good cosmesis in one to two treatment sessions and is well tolerated by patients. © 2013 British Association of Dermatologists.

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