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Studneva M.,Moscow State University | Mandrik M.,Moscow State University | Song S.,Florida College | Tretyak E.,FMBA | And 12 more authors.
EPMA Journal | Year: 2015

Predictive, Preventive and Personalized Medicine as the Medicine of the Future represents an innovative model for advanced healthcare and robust platform for relevant industrial branches for diagnostics and pharmaceutics. However, rapid market penetration of new medicines and technologies demands the implementation of reforms not only in the spheres of biopharmaceutical industries and healthcare, but also in education. Therefore, the problem of the fundamental, modern preparation of specialists in bioengineering and affiliated fields is becoming particularly urgent, and it requires significant revision of training programs of higher education practice into current medical universities. Modernization and integration of widely accepted medical and teaching standards require consolidation of both the natural sciences and medical sciences that may become the conceptual basis for a university medical education. The main goal of this training is not simply to achieve advanced training and expansion of technological skills, but to provide development of novel multifaceted approaches to build academic schools for future generations. © 2015 Studneva et al.


Shutov R.V.,Saint Petersburg State Chemical and Pharmaceutical Academy | Kuklina E.V.,Saint Petersburg State Chemical and Pharmaceutical Academy | Ivin B.A.,Saint Petersburg State Chemical and Pharmaceutical Academy
Tetrahedron Letters | Year: 2011

Reaction of 3-formylchromones with 2-aryl-4-hydroxy-6H-1,3-thiazin-6-ones in the presence of pyridine leads to formation of a mixture of novel N-thioaroyl-5-hydroxy-2H,5H-pyrano[3,2-]chromen-2-one-3-carboxamides and 2-aryl-5-(4′-oxochromen-3′-yl)-6,7-dihydro-4H,5H-pyrano[2,3-d][1,3] thiazine-4,7-diones. The yields of these compounds clearly depend on the nature of the substituent on the 3-formylchromone and on the reaction conditions. © 2010 Elsevier Ltd. All rights reserved.


Shutov R.V.,Saint Petersburg State Chemical and Pharmaceutical Academy | Sopova M.V.,Saint Petersburg State Chemical and Pharmaceutical Academy | Krylov A.V.,Saint Petersburg State Chemical and Pharmaceutical Academy | Kaluzhskikh A.N.,Saint Petersburg State Chemical and Pharmaceutical Academy | Ivin B.A.,Saint Petersburg State Chemical and Pharmaceutical Academy
Journal of Heterocyclic Chemistry | Year: 2015

A new and efficient route for the synthesis of derivatives of the poorly investigated pyrano[2,3-d][1,3]thiazine heterocyclic system is disclosed. These compounds were prepared via annulation of 2-aryl-4-hydroxy-6H-1,3-thiazine-6-ones with aliphatic and aromatic aldehydes in the presence of pyridine. The method is general and versatile, and the interaction is independent on the nature of the aldehyde, the only exceptions being formaldehyde and salicylaldehydes. © 2014 HeteroCorporation.

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