Saint Josephs Regional Medical Center

Paterson, NJ, United States

Saint Josephs Regional Medical Center

Paterson, NJ, United States
SEARCH FILTERS
Time filter
Source Type

PubMed | East Coast Advanced Plastic Surgery, PASE Healthcare, Cornell University and Saint Josephs Regional Medical Center
Type: Journal Article | Journal: Journal of clinical medicine | Year: 2015

An 87-year old Caucasian male with past medical history of rheumatoid arthritis (RA) and chronic kidney disease presents with left hand erythema, pain, tenderness, induration and edema. Clinically, these hand findings began proximal to the metacarpo-phalangeal joints and extended to the distal wrist. He was noted to have ipsilateral axillary lymph node enlargement but denied any constitutional signs or symptoms. Laboratory markers of inflammation were poor prognostic indicators due to relatively active RA, the use of chronic daily glucocorticoids and weekly adalimumab use. Oral antibiotics were administered with limited success leading to a skin biopsy which reported a hematogenously disseminated fungal panniculitis; cultures grew Cryptococcus neoformans, however, serum cryptococcal antigen was negative. With initial fluconazole treatment, skin findings and lymphadenopathy improved gradually over the next six months. However, the patients improvement stagnated and his condition reverted back to the state of initial presentation.


Slim J.,Saint Michaels Medical Center | Slim J.,Saint Josephs Regional Medical Center | Slim J.,New York Medical College | Saling C.F.,New York Medical College | Saling C.F.,Saint Michaels Medical Center
BioMed Research International | Year: 2016

Advancements in antiretroviral therapy have drastically increased the life expectancy for those infected with HIV. Today, a new subgroup of older patients with long-term controlled HIV exists, and its populace is continuously mounting. Therefore, it is essential to understand the enduring effects of chronic suppressed HIV infection in order to further improve HIV management in these patients. This paper will examine the role of HIV in chronic inflammation and immune dysfunction, the dynamic interaction that exists between comorbidity and HIV, and the potential consequences of long-term antiretroviral therapy in an effort to provide the best management options for the virally suppressed HIV patient. © 2016 Jihad Slim and Christopher F. Saling.


Shah A.M.,Saint Josephs Regional Medical Center | Eddi R.,Saint Josephs Regional Medical Center | Eddi R.,Seton Hall University | Kothari S.T.,Saint Josephs Regional Medical Center | And 6 more authors.
Journal of the Pancreas | Year: 2010

Context Acute pancreatitis is diagnosed on the basis of clinical features, biochemical tests and imaging studies. Normal serum amylase level has been reported in the setting of acute pancreatitis but normal serum lipase level in acute pancreatitis is extremely rare. Case report Herein, we present a case series of acute pancreatitis with normal serum lipase levels along with a review of the topic. Conclusion In appropriate clinical setting, the diagnosis of acute pancreatitis should be entertained even with normal serum amylase and lipase levels.


Sathe S.,Saint Josephs Regional Medical Center
Current Pain and Headache Reports | Year: 2013

In the current classification of headache disorders, headache attributable to genetic disorders is not classified separately, rather as headache attributed to cranial or cervical vascular disorder. The classification thus implies that a vascular pathology causes headache in these genetic disorders. Unquestionably, migraine is one of the prominent presenting features of several genetic cerebral small vessel diseases such as cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy, retinal vasculopathy with cerebral leukodystrophy, and hereditary infantile hemiparessis, retinal arteriolar tortuosity and leukoencephalopahty. Shared genetic features, increased susceptibility, and/or vascular endothelial dysfunction may play a role in pathogenesis of migraine. Common or overlapping pathways involving the responsible genes may provide insight regarding the pathophysiological mechanisms that can explain their comorbidity with migraine. This review focuses on clinical features of genetic vasculopathies. An independent category - migraine related to genetic disorders - should be considered to classify these disorders. © 2013 Springer Science+Business Media New York.


Pastakia S.D.,Purdue University | Pastakia S.D.,Moi University | Fohl A.L.,University of Michigan | Schellhase E.M.,Purdue University | And 2 more authors.
Journal of the American Pharmacists Association | Year: 2010

Objectives: To assess the frequency of indications for vitamin K antagonist (VKA) therapy in the inpatient and outpatient setting in Eldoret, Kenya, and to describe the strategies used for managing these conditions. Methods: All inpatient admissions during a 1.5-month period were prospectively assessed for any indications for VKA therapy by clinical pharmacy staff. For the outpatient assessment, the files of all patients receiving care in the outpatient adult cardiology clinic within the previous 6 months were identified and evaluated for indications for VKA therapy. For patients identified with an indication for VKA therapy, additional information was collected, including the VKA indication, pharmacologic management, and any other risk-modifying conditions. Results: In the primary analysis, 20 of the 554 patients admitted to the public adult wards (3.61% [95% CI 2.14-5.08]) were candidates for VKA therapy. Of the 168 outpatient cardiology clinic charts reviewed, 72 patients (42.8% [37.96-47.76]) had indications for VKA therapy. In the secondary analysis, 70% of the inpatient population and 93% of the outpatient population received suboptimal VKA therapy. Of these patients in need of VKA therapy, 53.3% were on aspirin therapy only and 33.7% were not receiving any pharmacologic therapy. Conclusion: As developing countries begin to address the growing burden of chronic diseases, a commensurate focus on providing infrastructure for comprehensive cardiovascular care, including an organized VKA monitoring service, needs to occur.


PubMed | Saint Josephs Regional Medical Center
Type: Case Reports | Journal: JOP : Journal of the pancreas | Year: 2010

Acute pancreatitis is diagnosed on the basis of clinical features, biochemical tests and imaging studies. Normal serum amylase level has been reported in the setting of acute pancreatitis but normal serum lipase level in acute pancreatitis is extremely rare.Herein, we present a case series of acute pancreatitis with normal serum lipase levels along with a review of the topic.In appropriate clinical setting, the diagnosis of acute pancreatitis should be entertained even with normal serum amylase and lipase levels.


PubMed | Saint Josephs Regional Medical Center
Type: Journal Article | Journal: The Physician and sportsmedicine | Year: 2010

Physical activity decreases insulin resistance and can aid in both preventing type 2 diabetes mellitus and managing the disease. Before patients with type 2 diabetes begin an exercise program, they should undergo a preparticipatory clinical assessment and screening for micro- and macrovascular disease. Patients older than 35 and those with additional cardiovascular risk factors, peripheral vascular disease, long-standing disease, or peripheral neuropathy should have an exercise stress test. Adequate glycemic control and selection of appropriate physical activity, such as brisk walking or swimming, are essential to avoid associated complications. Patients on diabetes medications should monitor blood glucose levels and adjust their diet to minimize fluctuations in blood glucose during exercise.


PubMed | Saint Josephs Regional Medical Center
Type: Journal Article | Journal: The Physician and sportsmedicine | Year: 2010

Those who have type 1 diabetes mellitus should include regular sports or recreational activities in their overall healthcare programs. Essential responsibilities of physicians who treat these patients include preparticipation clearance, education about blood glucose self-monitoring, exercise prescription, aggressive dietary and insulin management plans, identification of risk factors and potential complications, and ongoing education. Exercise has risks and benefits that must be understood so that participation yields a safe, enjoyable outcome that meshes with the patients culture, activity goals, and lifestyle.


PubMed | Saint Josephs Regional Medical Center
Type: Case Reports | Journal: Hepato-gastroenterology | Year: 2012

Liver cirrhosis is generally considered irreversible but there are reports in which there is documented reversal of fibrosis/cirrhosis in various clinical conditions like Wilsons disease, hemochromatosis, primary biliary cirrhosis and autoimmune hepatitis. The subgroup of patients with autoimmune hepatitis that will have reversal of cirrhosis is not known. We present two cases with documented liver cirrhosis that had reversal of cirrhosis after treatment with immunosuppressive agents. We postulate that patients presenting with acute hepatitis and no other fibrogenic factors have higher chances of reversal of liver cirrhosis as compared to those presenting as chronic liver injury.


PubMed | Saint Josephs Regional Medical Center
Type: Journal Article | Journal: Annals of translational medicine | Year: 2016

Postmenopausal vaginal bleeding is a rare presentation of Krukenberg tumor (KT). Here we report a very unusual presentation of gastric cancer in a postmenopausal female patient, who presented with complaint of vaginal bleeding. She was found to have KT of the left ovary after total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO). She was subsequently diagnosed with primary gastric cancer. To the best of our knowledge, this is the first case report of KT with a primary T1a gastric cancer and no evidence of metastasis anywhere else except for large ovarian mass.

Loading Saint Josephs Regional Medical Center collaborators
Loading Saint Josephs Regional Medical Center collaborators