Safe , Llc | Date: 2016-10-05
A cage assembly configured to raise and lower with respect to a container which has an opening closed by a hatch cover. The cage assembly comprises a rail structure having a proximal side, a distal side, and first and second ends defining a generally rectangular enclosed area in which a worker can stand. The rail structure further defines an opening in the proximal side so that a worker can access the enclosed area. Moreover, the rail structure further comprises a plurality of parallel rails including a top rail and a lower rail, with the top rail having a generally rectangular configuration to define the enclosed area. A respective bump out is defined by the rail structure on at least one of the proximal and distal sides thereof to facilitate opening of the hatch cover. The bump out is formed at least in part by a configuration of the lower rail.
Safe , Llc | Date: 2017-03-29
The invention relates to a trajectory guidance instrument that is securable to a surgical tool for use in conjunction with X-ray machines. More particularly, the device includes a radiolucent outrigger having radiodense indicia disposed on the outrigger so that the radiodense indicia is visible via an X-ray machine to provide an angular trajectory for the instrument. The outrigger is securable to various surgical tools for the purpose of providing real time trajectory guidance to surgeons during a procedure. In general, the precision trajectory guidance instrument comprises a substantially rigid outrigger device which it securable to a portion of the surgical tool for trajectory guidance. The trajectory guidance instrument may be attached with clips, fasteners, adhesives, hook and loop or the like.
Safe , Llc | Date: 2016-11-29
A verification method performed by a verification entity including receiving, from a corporate entity, a request for verification prompted by a consumer, sending, to at least three independent sources, a request for corporate information corresponding to the corporate entity, comparing, by the verification entity, corporate information obtained from the corporate entity to corporate information received from the at least three independent sources, and providing, to the consumer, a safe certificate when the corporate information obtained from the corporate entity matches the corporate information received from the at least three independent sources.
Safe , Llc | Date: 2017-03-15
This invention relates to processes and systems for converting fresh food waste into nutrient rich hydrolysates and particulate compositions. The invention also relates to the hydrolysates and compositions useful, for example, as fertilizers, feedstock or other nutrient supplements.
Safe , Llc | Date: 2017-07-05
According to one or more embodiments disclosed herein is a method of transporting equipment between sea- surface and seafloor by providing a structure with a subsea equipment package mounted thereon. The structure is used for installation and recovery in a subsea environment by changing the buoyancy of the structure or ballasting the structure to effect a controlled sinking motion.
Safe , Llc | Date: 2016-02-26
A safety system includes a wearable device having means to determine whether a child has been left in a car seat and further having means to detect the wearable devices global position and the ambient temperature, heart rate, and activity of a person wearing the wearable device. The wearable device can send notice to a smartphone or other designated device when certain specified conditions have been met or exceeded. The information monitored and/or gathered can be stored and retrieved as needed.
Safe , Llc | Date: 2016-08-31
A gate comprises a spring-loaded hinge arrangement defining a rotational axis. A gate structure having a first support arm connected to a first end of the hinge arrangement is also provided. The gate structure is rotatable about the rotational axis. A spring-loaded hinge arrangement includes an outer hinge tube fixedly connectable to an adjacent structure and an inner hinge tube received in the outer hinge tube. The inner hinge tube has a first portion and a second portion movable with respect to each other, the second portion of the inner hinge tube being fixed with respect to the outer hinge tube and the first portion of the inner hinge tube being fixed with respect to the support arm.
Agency: Department of Health and Human Services | Branch: National Institutes of Health | Program: STTR | Phase: Phase II | Award Amount: 223.28K | Year: 2016
DESCRIPTION provided by applicant The Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetes by transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluid blood ultrafiltrate so that the cells ae protected from immune rejection but have optimal exchange of oxygen and nutrients This compact device is totally implanted in the subcutaneous space and the unique design facilitates loading reloading and biopsy of cell products using simple needle access through the skin The pump controlled ultrafiltrate perfusion system supplies oxygen nutrients and flushes metabolic waste Thanks to the immunoisolation environment survival of transplanted islets can be achieved in complete absence of immunosuppression This approach could solve the issues in islet transplantation namely the complications of immunosuppressive medication and scarcity of human donor pancreases which issues have severely limited islet cell transplantation to a select group of patients who suffer from insufficient control of their blood sugar level and hence are at risk for developing diabetes complications Control of blood sugar levels is restored in most patients who receive an allograft transplant but unfortunately long term allograft survival rates are low and the most patients will eventually require retransplant to continue benefiting from the therapy Success of the Cell SafeTM device has an immediate implication for human islet allotransplantation but also would facilitate `unlimitedandapos cell sources like xenogeneic porcie islets or stem cell derived insulin producing cells Taken together this technology presents a major paradigm shift in cell replacement therapy The Phase project will evaluate the capacity of the device islet reloading schemes and characterize factors in blood ultrafiltrate tht support islet function and survival that was demonstrated in preliminary studies At the same time in vitro stress testing of the device will be performed to prepare for clinical manufacturing The Phase will focus on preclinical pivotal trials addressing safety tolerability and efficacy intended to support regulatory approval of this device with the final aim of meeting the tremendous clinical need for safe effective and durable islet replacement that also enables expanded accessibility of this therapy in diabetes patients PUBLIC HEALTH RELEVANCE The goal of this project is to develop an immunosuppression free therapy to replace defective insulin production using a highly compatible bioartificial pancreas implanted just under the skin that supports transplanted pancreatic islets using the patientandapos s own tissue fluid for active perfusion to provide oxygen and nutrients and bring secreted insulin in the body This is a fundamentally new approach to replace insulin producing cells with the potential to reverse diabetes and prevent diabetes complications to answer the unmet medical need in type diabetes patients
Safe , Llc | Date: 2016-05-18
A surgical guide wire or K-wire and method of use are provided. The K-wire or guide wire has opposite end portions and a shank portion in between. One end portion has a deformable end portion that, once outside of a confining guide passage, can be deformed to present a projected forward facing area that is larger than the transverse cross section of the K-wire or guide wire while in the passage. The increased area will provide increased resistance to additional forward axial movement into the surgical site.
Safe , Llc | Date: 2016-06-30
Various embodiments of methods and apparatus for attribute-based navigation are disclosed. In one embodiment, responsive to a request for a location having a variable attribute, a destination is selected based at least in part upon a value of the variable attribute. Navigation instructions from a current location are provided.