Goleta, CA, United States
Goleta, CA, United States

Time filter

Source Type

The invention relates to a trajectory guidance instrument that is securable to a surgical tool for use in conjunction with X-ray machines. More particularly, the device includes a radiolucent outrigger having radiodense indicia disposed on the outrigger so that the radiodense indicia is visible via an X-ray machine to provide an angular trajectory for the instrument. The outrigger is securable to various surgical tools for the purpose of providing real time trajectory guidance to surgeons during a procedure. In general, the precision trajectory guidance instrument comprises a substantially rigid outrigger device which it securable to a portion of the surgical tool for trajectory guidance. The trajectory guidance instrument may be attached with clips, fasteners, adhesives, hook and loop or the like.


Patent
Safe , Llc | Date: 2016-05-05

A liquid storage tank comprising an outer container wherein the outer container is rigid and has at least one inner container disposed within the outer container. The at least one inner container contains at least one stored liquid which may be refilled from a surface vessel or host facility. The at least one inner container is flexible and pressure balanced while the volume of the outer container remains fixed, and the volume of the at least one inner containers is variable. Disposed on the outer container is a balance assembly containing an isolation valve, a check valve, and a flexible bladder. The balance assembly allows for the hydrostatic pressure to be maintained during chemical dosing and tank raising operations.


Patent
Safe , Llc | Date: 2016-02-26

A safety system includes a wearable device having means to determine whether a child has been left in a car seat and further having means to detect the wearable devices global position and the ambient temperature, heart rate, and activity of a person wearing the wearable device. The wearable device can send notice to a smartphone or other designated device when certain specified conditions have been met or exceeded. The information monitored and/or gathered can be stored and retrieved as needed.


Patent
Safe , Llc | Date: 2016-02-16

This invention relates to processes and systems for converting fresh food waste into nutrient rich hydrolysates and particulate compositions. The invention also relates to the hydrolysates and compositions useful, for example, as fertilizers, feedstock or other nutrient supplements.


Patent
Safe , Llc | Date: 2016-08-31

A gate comprises a spring-loaded hinge arrangement defining a rotational axis. A gate structure having a first support arm connected to a first end of the hinge arrangement is also provided. The gate structure is rotatable about the rotational axis. A spring-loaded hinge arrangement includes an outer hinge tube fixedly connectable to an adjacent structure and an inner hinge tube received in the outer hinge tube. The inner hinge tube has a first portion and a second portion movable with respect to each other, the second portion of the inner hinge tube being fixed with respect to the outer hinge tube and the first portion of the inner hinge tube being fixed with respect to the support arm.


Grant
Agency: Department of Health and Human Services | Branch: National Institutes of Health | Program: STTR | Phase: Phase II | Award Amount: 223.28K | Year: 2016

DESCRIPTION provided by applicant The Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetes by transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluid blood ultrafiltrate so that the cells ae protected from immune rejection but have optimal exchange of oxygen and nutrients This compact device is totally implanted in the subcutaneous space and the unique design facilitates loading reloading and biopsy of cell products using simple needle access through the skin The pump controlled ultrafiltrate perfusion system supplies oxygen nutrients and flushes metabolic waste Thanks to the immunoisolation environment survival of transplanted islets can be achieved in complete absence of immunosuppression This approach could solve the issues in islet transplantation namely the complications of immunosuppressive medication and scarcity of human donor pancreases which issues have severely limited islet cell transplantation to a select group of patients who suffer from insufficient control of their blood sugar level and hence are at risk for developing diabetes complications Control of blood sugar levels is restored in most patients who receive an allograft transplant but unfortunately long term allograft survival rates are low and the most patients will eventually require retransplant to continue benefiting from the therapy Success of the Cell SafeTM device has an immediate implication for human islet allotransplantation but also would facilitate `unlimitedandapos cell sources like xenogeneic porcie islets or stem cell derived insulin producing cells Taken together this technology presents a major paradigm shift in cell replacement therapy The Phase project will evaluate the capacity of the device islet reloading schemes and characterize factors in blood ultrafiltrate tht support islet function and survival that was demonstrated in preliminary studies At the same time in vitro stress testing of the device will be performed to prepare for clinical manufacturing The Phase will focus on preclinical pivotal trials addressing safety tolerability and efficacy intended to support regulatory approval of this device with the final aim of meeting the tremendous clinical need for safe effective and durable islet replacement that also enables expanded accessibility of this therapy in diabetes patients PUBLIC HEALTH RELEVANCE The goal of this project is to develop an immunosuppression free therapy to replace defective insulin production using a highly compatible bioartificial pancreas implanted just under the skin that supports transplanted pancreatic islets using the patientandapos s own tissue fluid for active perfusion to provide oxygen and nutrients and bring secreted insulin in the body This is a fundamentally new approach to replace insulin producing cells with the potential to reverse diabetes and prevent diabetes complications to answer the unmet medical need in type diabetes patients


A system and method of securing an opening or access point may transition to a first alarm state in response to an indication that the access point is open, sound a first audible alarm in response to an open access point, silence the first audible alarm and return to the armed state in response to a disarming action by a user, transition to a first disarmed state in response to an indication of the disarming action by the user, initiate a countdown from a first predetermined time period in response to the disarming action by the user, return to the armed state upon the expiration of the first predetermined period, transition to a second disarmed state in response to an indication of a closed access point, and initiate a countdown from a second predetermined period in response to a remaining first predetermined period being greater than the second predetermined period.


Patent
Safe , Llc | Date: 2016-02-16

This invention relates to processes and systems for converting fresh food waste into nutrient rich hydrolysates and particulate compositions. The invention also relates to the hydrolysates and compositions useful, for example, as fertilizers, feedstock or other nutrient supplements.


Patent
Safe , Llc | Date: 2016-05-18

A surgical guide wire or K-wire and method of use are provided. The K-wire or guide wire has opposite end portions and a shank portion in between. One end portion has a deformable end portion that, once outside of a confining guide passage, can be deformed to present a projected forward facing area that is larger than the transverse cross section of the K-wire or guide wire while in the passage. The increased area will provide increased resistance to additional forward axial movement into the surgical site.


Patent
Safe , Llc | Date: 2016-06-30

Various embodiments of methods and apparatus for attribute-based navigation are disclosed. In one embodiment, responsive to a request for a location having a variable attribute, a destination is selected based at least in part upon a value of the variable attribute. Navigation instructions from a current location are provided.

Loading SAFE , LLC collaborators
Loading SAFE , LLC collaborators