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Košice, Slovakia

Ghorbani Saeedian R.,University of P.J. Safarik | Nagyova I.,University of P.J. Safarik | Krokavcova M.,Safarik University | Skorvanek M.,University of P.J. Safarik | And 6 more authors.
Disability and Rehabilitation | Year: 2014

Purpose: To explore how social support is associated with anxiety and depression in Parkinson's disease (PD) patients controlling for gender, disease duration and disease severity.Methods: The sample consisted of 124 patients (52.4% male; mean age 68.1 ± 8.4 years; mean disease duration 6.3 ± 5.5 years). Anxiety and depression were measured with the Hospital Anxiety and Depression Scale, social support with the Multidimensional Scale of Perceived Social Support and disease severity with the Unified Parkinson Disease Rating Scale. Data were analyzed using linear regression.Results: Gender, disease duration, disease severity and social support explained 31% of the total variance in anxiety in younger PD patients but did not significantly contribute to the explanation of depression. In the older group, this model explained 41% of the variance in depression but did not significantly contribute to the explanation of anxiety.Conclusion: PD patients experience the positive influence of social support differently according to age. In the younger group, disease duration plays the primary role regarding anxiety. In the older group, poor social support especially from friends is associated with more depression after controlling for the relevant variables.Implications of RehabilitationPD is a disease of older age with a neurodegenerative character and treatment should focus on increasing quality of life.Anxiety and depression are common co-morbidities in PD patients.The support network should also be screened regularly and involved in enhancing the quality of life. © 2014 Informa UK Ltd.


Strojny L.,Safarik University in Kosice | Bomba A.,Safarik University in Kosice | Hijova E.,Safarik University in Kosice | Chmelarova A.,Safarik University in Kosice | And 6 more authors.
Czech Journal of Animal Science | Year: 2011

Effects of the probiotic (PRO) Lactobacillus plantarum and of the combination of PRO and the prebiotic (PRE) inulin enriched with oligofructose (2%), and PRO with Lini oleum virginale (O) on counts of lactobacilli and coliforms and enzymatic activities in faeces of rats were studied. The rats (n = 60) were divided into 5 groups of 12 subjects. The animals were fed on a high fat diet (10%) for 8 weeks of experiment. Colon cancer was induced by the application of 1,2-dimethylhydrazine (DMH) twice a week in a dose of 20 mg/kg s.c. in groups G2-G5. The rats in group 1 (control 1) received a diet without any supplements. The rats in group 2 (control 2) received 1,2 DMH without any supplements. The rats in group 3 received PRO, group 4 PRO and PRE, and group 5 received PRO and O. A significant decrease (P < 0.05) of coliforms was found out after the application of PRO, PRO-O, and PRO-PRE in comparison with control group G2. Significantly higher (P < 0.05) counts of lactobacilli were determined after the application of PRO-O and PRO-PRE. Significantly lower (P < 0.001) activities of β-galactosidase, β-glucuronidase and α-glucosidase were observed in PRO, PRO-PRE and PRO-O, while in the case of the enzyme β-glucosidase the activity was lower only after the addition of PRO-O. The protective effect of lactobacilli was observed in the order PRO-O, PRO-PRE, and PRO. It was shown that combinations of PRO-O and PRO-PRE had a synergistic effect which was higher than the effect of administering only PRO.


Andrejccaronakova Z.,University of Veterinary Medicine in Kosice | Petrilla V.,University of Veterinary Medicine in Kosice | Tomeckova V.,Safarik University in Kosice | Toth S.,Safarik University in Kosice | And 7 more authors.
Spectroscopy Letters | Year: 2015

A novel approach to the study of venoms characterizes and compares the venom structure of genus Dendroaspis presented in this work. The complex molecular structure of individual venoms of genus Dendroaspis was defined graphically as a record of synchronous fluorescence fingerprint and atomic force microscopy. Simple comparison of these methods mentioned above of individual analyzed venom samples will immediately reveal changes in each venom composition. Application of these methods with electrophoresis and total protein concentration are new alternatives that were used for monitoring venom composition in selected snakes. Electrophoretogram of black mamba with very low content of total proteins contained the largest number of separated fractions, whereas synchronous fluorescence analysis showed that the highest endogenous fluorescence was found in the venom of black mamba compared with the venom of green mambas, respectively. Our results confirmed different molecular structure in the venom of the genus Dendroaspis. The practical advantages of the selected techniques are high sensitivity and minimal quantity of venom required for the assay. These novel methods show that the least toxic Dendroaspis intermedius contained the greatest amount of proteins contrary to Dendroaspis polylepis with a considerably lower content of proteins but the highest toxic bioactivity. Copyright © 2015 Taylor & Francis Group, LLC.


Prihodova L.,Safarik University in Kosice | Prihodova L.,Nephrology and Dialysis Center Fresenius Kosice | Nagyova I.,Safarik University in Kosice | Rosenberger J.,Safarik University in Kosice | And 9 more authors.
Transplant International | Year: 2010

Health-related quality of life (HRQoL) has become an important outcome in the evaluation of kidney transplantation (KT). Although the medical and sociodemographic predictors of HRQoL in patients after KT are well known, there is still a lack of knowledge about the psychological factors involved. This study focuses on the role of personality and actual psychological distress in predicting HRQoL after KT. Sociodemographic (gender, age, education, average income), medical (glomerular filtration, serum albumin, number of co-morbid diseases) and psychological data (neuroticism, extroversion, psychological distress) were collected from 177 (60.5% male subjects; 48 ± 12.1 years) kidney transplant recipients, and physical and mental HRQoL were measured using the SF-36. A univariate general linear model analysis was performed. Higher physical HRQoL was associated with younger age, higher education and income, a low number of co-morbid diseases, lower neuroticism and distress. Higher mental HRQoL was associated with higher education and income, longer time from KT, higher extroversion, lower neuroticism and distress. In both physical and mental HRQoL, actual distress was the best predictor, even when controlled for neuroticism. These results confirm the importance of psychological distress in patients and its impact on their HRQoL after KT and can be applied in intervention programs focused on increasing HRQoL. © 2009 European Society for Organ Transplantation.


Uher I.,Safarik University in Kosice | Bukova A.,Safarik University in Kosice | Svedova M.,University of Presov | Kuchelova Z.,Safarik University in Kosice | Jozef P.,Safarik University in Kosice
Sport Science | Year: 2016

Strong state of science supports the health benefits of regular physical activity in young population. Therefore, it is understandable that the factors that influence physical activity in adolescent population can aid the proposal of more effective interventions that will help young people to become more active. Previous studies, investigating correlates of youth physical activity, life style, demographic characteristics and body fat have produced conflicting results. All study participants completed a standard questionnaire on selected correlates of parents’ involvement in physical activity and selected demographic characteristics. Percentage of body fat accumulation in freshman students was investigated by the means of Omron BF 511 device. Results were summarized using a comprehensive analysis for young female adults aged 18 to 20,n=1139, from University ofP.J. Šafárik in Košice 2012. Our cross-sectional study was part of VEGA project No. 1/1343/12 “Selected risk factors of obesity and its prevention by physical activity”. The variables that were consistently associated with higher percentage of body fat in students were lack of parents’ adoption to healthy lifestyle and participation and guidance of their own kids towards physical activity. On the contrary, we did not find statistical significance between selected demographic characteristics and higher percentage of body fat in the adolescent sample. In order to improve the state of health in the young population, we recommend health promotion activity campaign with relevant tailored messages that should target the parent population. These consistently related variables should be confirmed in prospective studies, and intervention to improve the modifiable variables should be developed and evaluated in order to improve overall healthy behavior of young population. © 2016, Univerzitet u Travniku. All rights reserved.

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