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Istanbul, Turkey

Sabancı University, established in 1994, is a private university in Istanbul, Turkey. Its first students matriculated in 1999. The first academic session started on October 20, 1999 . Wikipedia.

Ozaydin-Ince G.,Sabanci University | Coclite A.M.,Massachusetts Institute of Technology | Gleason K.K.,Massachusetts Institute of Technology
Reports on Progress in Physics | Year: 2012

Polymers with their tunable functionalities offer the ability to rationally design micro- and nano-engineered materials. Their synthesis as thin films have significant advantages due to the reduced amounts of materials used, faster processing times and the ability to modify the surface while preserving the structural properties of the bulk. Furthermore, their low cost, ease of fabrication and the ability to be easily integrated into processing lines, make them attractive alternatives to their inorganic thin film counterparts. Chemical vapor deposition (CVD) as a polymer thin-film deposition technique offers a versatile platform for fabrication of a wide range of polymer thin films preserving all the functionalities. Solventless, vapor-phase deposition enable the integration of polymer thin films or nanostructures into micro- and nanodevices for improved performance. In this review, CVD of functional polymer thin films and the polymerization mechanisms are introduced. The properties of the polymer thin films that determine their behavior are discussed and their technological advances and applications are reviewed. © 2012 IOP Publishing Ltd.

Alpaslan E.,Sabanci University
International journal of nanomedicine | Year: 2011

Materials currently used for bladder applications often suffer from incomplete coverage by urothelial cells (cells that line the interior of the bladder and ureter) which leads to the continuous exposure of the underlying materials aggravating an immune response. In particular, a ureteral (or sometimes called an ureteric or bladder) stent is a thin tube inserted into the ureter to prevent or treat obstruction of urine flow from the kidney. The main complications with ureteral stents are infection and blockage by encrustation, which can be avoided by promoting the formation of a monolayer of urothelial cells on the surface of the stent. Nanotechnology (or the use of nanomaterials) may aid in urothelialization of bladder stents since nanomaterials have been shown to have unique surface energetics to promote the adsorption of proteins important for urothelial cell adhesion and proliferation. Since many bladder stents are composed of titanium, this study investigated the attachment and spreading of human urothelial cells on different nanotextured titanium surfaces. An inexpensive and effective scaled up anodization process was used to create equally distributed nanotubular surfaces of different diameter sizes from 20-80 nm on titanium with lengths approximately 500 nm. Results showed that compared to untreated titanium stents and 80 nm diameter nanotubular titanium, 20 nm diameter nanotubular titanium stents enhanced human urothelial cell adhesion and growth up to 3 days in culture. In this manner, this study suggests that titanium anodized to possess nanotubular surface features should be further explored for bladder stent applications.

Dynamic nuclear polarization (DNP) employs paramagnetic species to increase the NMR signal of nuclear spins. In liquids, the efficiency of the effect depends on the strength of the interaction between the electron and nuclear spins and the time scales on which this interaction is modulated by the physical motion of the spin-bearing molecules. An approach to quantitatively predict the contribution of molecular motions to the DNP enhancement using molecular dynamics (MD) simulations is developed and illustrated for the nitroxide radical TEMPOL in liquid toluene. A multi-resolution strategy that combines explicit treatment of the solvent at short distances from the free radical with implicit description at large intermolecular distances is adopted. Novel analytical expressions are obtained to correct for the finite spatial extent of the MD simulations. The atomistic and analytical descriptions are sewn seamlessly together by ensuring that for molecular trajectories that start in the near (explicit) region and end in the distant (implicit) region the analytical dipolar spectral densities reproduce the MD estimates. The spectral densities obtained from the developed approach are used to calculate DNP coupling factors separately for the ring and methyl protons of toluene. The agreement with previously reported experimental DNP data at a magnetic field of 3.4 T is noteworthy and encouraging. Maximum obtainable DNP enhancements at other magnetic fields are predicted. © the Owner Societies 2013.

Kosar A.,Sabanci University
International Journal of Thermal Sciences | Year: 2010

Heat and fluid flow in microchannels of size (200μm × 200 μm, 5 cm long) of different substrate thicknesses (t = 100 μm-1000 μm) and different MEMS (Microelectromechanical Systems) materials (Polyimide, Silica Glass, Quartz, Steel, Silicon, Copper) was studied to observe the effects of thermal conductivity and substrate thickness on convective heat transfer in laminar internal flows. The results of the model were first validated by the theoretical results recommended by standard forced convection problem with H1 (Constant heat flux boundary condition) condition before the results from the actual microchannel configurations were obtained. Thereafter, general Nusselt number results were obtained from the models of many microchannel configurations based on the commercial package COMSOL MULTIPHYSICS® 3.4 and were discussed on both local and average basis. A general Nusselt number correlation for fully developed laminar flow was developed as a function of two dimensionless parameters, namely Bi, Biot number and relative conductivity k*, to take the conduction effects of the solid substrate on heat transfer into account. It was also demonstrated when the commonly used assumption of constant heat flux boundary (H1) condition is applicable in heat and fluid flow analysis in microfluidic systems. For this, a new dimensionless parameter was employed. A value of 1.651 for this suggested dimensionless parameter (Bi0.04k*-0.24) corresponds to 95% of the Nusselt number associated with the constant heat flux boundary condition so that it could be set as a boundary for the applicability of constant heat flux boundary (H1) condition in microfluidic systems involving heat transfer. © 2009 Elsevier Masson SAS. All rights reserved.

Catay B.,Sabanci University
Expert Systems with Applications | Year: 2010

The Vehicle Routing Problem with Pickup and Delivery (VRPPD) is a variant of the Vehicle Routing Problem where the vehicles are not only required to deliver goods but also to pick up some goods from the customers. Given a fleet of vehicles and a set of customers with known delivery and/or pickup demands for one commodity VRPPD determines a set of vehicle routes originating and ending at a single depot and visiting all customers exactly once. The objective is to minimize the total distance traversed. In this paper, we consider a special case of the VRPPD where each customer has both a delivery and a pickup demand to be satisfied simultaneously. For this problem, we propose an ant colony algorithm employing a new saving-based visibility function and pheromone updating procedure. The numerical tests with the wellknown benchmark problems from the literature show that the proposed approach provides competitive results and improves several best-known solutions. © 2010 Elsevier Ltd. All rights reserved.

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