Liu X.,A+ Network |
Invernizzi P.,University of California at Davis |
Lu Y.,University of Texas M. D. Anderson Cancer Center |
Kosoy R.,University of California at Davis |
And 79 more authors.
A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from the Italian cohort replicated IL12A and IL12RB associations, and a combined meta-analysis using a Canadian dataset identified newly associated loci at SPIB (P = 7.9 × 10-11, odds ratio (OR) = 1.46), IRF5-TNPO3 (P = 2.8 × 10 -10, OR = 1.63) and 17q12-21 (P = 1.7 × 10-10, OR = 1.38). © 2010 Nature America, Inc. All rights reserved. Source