Aachen, Germany
Aachen, Germany

RWTH Aachen University is a research university of technology located in Aachen, North Rhine-Westphalia, Germany. With over 40,000 students enrolled in 130 study programs, it is the largest technical university in Germany. The institution maintains close links to industry and accounts for the highest amount of third-party funds of all German universities in both absolute and relative terms per faculty member.In 2007, RWTH Aachen was chosen by DFG as one of nine German Universities of Excellence for its future concept RWTH 2020: Meeting Global Challenges and additionally won funding for one graduate school and three clusters of excellence. In 2012, RWTH Aachen was selected again as a University of Excellence and altogether financially endowed for one graduate school and two clusters of excellence. RWTH Aachen is one of only six German universities to retain this status from the previous funding period of 2007 - 2012.RWTH Aachen is a founding member of IDEA League, a strategic alliance of five leading universities of technology in Europe. The university is also a member of TU9, DFG and the Top Industrial Managers for Europe network. Wikipedia.

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The objective of the paper is the quantification of effects of erodent flow kinetic energy and exposure time on the erosion of cement-based composites with high-speed hydro-abrasive jets. The erodent flow kinetic energy is varied due to changes in erodent velocity, traverse rate and erodent particle mass-flow rate. For a given traverse rate, the relationship between volumetric erosion rate and erodent flow kinetic energy follows a power function with power exponents between 0.49 and 0.66. The kinetic energy of the erodent flow is not a sufficient measure for the material removal capacity of high-speed hydro-abrasive flow. A critical exposure time must be realized in order to eliminate traverse rate effects. Exposure time effects are characterized with a Weibull-type function, whereby the shape parameter k of the function depends on erosion mode and material response. If incremental erosion modes dominate the material removal process: k>1. If continuous erosion modes control the material removal process: k≤1. It is supposed that k exceeds unity if a threshold fracture toughness of the composites is exceeded. © 2017 Elsevier B.V.

Von Pfingsten G.,RWTH Aachen | Steentjes S.,RWTH Aachen | Hameyer K.,RWTH Aachen
IEEE Transactions on Industrial Electronics | Year: 2017

In this paper, the global operating point dependent losses of induction machines are studied by using a local transient loss formulation. The level of flux, the machine is operated at, depends on the operation mode of the inverter. Hence, for precise loss modeling of inverter driven induction machines at the machine design stage, the time and spatial distribution of flux density and the influence of choosing the best operating point is included. A loss scaling method is developed to map iron losses calculated at a single synchronous frequency to other frequencies along the torque-speed map. The modeled losses and operating points are compared to extensive machine measurements. By way of example, the effect of different electrical steel grades tailored either to low losses or preferable magnetizability on the machine performance is investigated. © 2016 IEEE.

Marx N.,RWTH Aachen | McGuire D.K.,University of Texas Southwestern Medical Center
European Heart Journal | Year: 2016

Patients with type 2 diabetes mellitus (T2D) exhibit an increased risk for cardiovascular (CV) events. Hyperglycaemia itself contributes to the pathogenesis of atherosclerosis and heart failure (HF) in these patients, but glucose-lowering strategies studied to date have had little to no impact on reducing CV risk, especially in patients with a long duration of T2D and prevalent CV disease (CVD). Sodium glucose cotransporter-2 (SGLT2) inhibitors are a novel class of anti-hyperglycaemic medications that increase urinary glucose excretion, thus improving glycaemic control independent of insulin. The recently published CV outcome trial, EMPA-REG OUTCOME, demonstrated in 7020 patients with T2D and prevalent CVD that the SGLT2-inhibitor empagliflozin significantly reduced the combined CV endpoint of CV death, non-fatal myocardial infarction, and non-fatal stroke vs. placebo in a population of patients with T2D and prevalent atherosclerotic CVD. In addition and quite unexpectedly, empagliflozin significantly and robustly reduced the individual endpoints of CV death, overall mortality, and hospitalization for HF in this high-risk population. Various factors beyond glucose control such as weight loss, blood pressure lowering and sodium depletion, renal haemodynamic effects, effects on myocardial energetics, and/or neurohormonal effects, among others may contribute to these beneficial effects of SGLT2-inhibition. The present review summarizes known and postulated effects of SGLT2-inhibition on the CV system and discusses the role of SGLT2-inhibition for the treatment of high-risk patients with T2D and CVD. © The Author 2016.

BACKGROUND: Clinical studies have raised concerns about the safety of 6% hydroxyethylstarch (HES) 130/0.42, but the pathomechanisms of this renal impairment remain unknown. To evaluate the effects of different HES concentrations, molar substitutions and molecular weights in HES-induced renal impairment, we used a porcine two-hit model that combined haemorrhagic and septic shock.METHODS: We conducted a prospective, randomised, double-blinded, controlled study in a university animal laboratory. Thirty anaesthetised and ventilated pigs were randomised to receive volume replacement therapy using 6% HES130/0.42, 6% HES200/0.5, 10% HES130/0.42 or 10% HES200/0.5, all dissolved in 0.9% NaCl rather than 0.9% NaCl alone. First, we bled the animals until they reached half of their baseline mean arterial pressure (MAP) for 45 minutes followed by fluid resuscitation. As a second hit, sepsis was induced using an Escherichia coli-laden clot 6 hours after haemorrhagic shock. Volume resuscitation started with a delay of two hours and a central venous pressure goal of 12 mmHg.RESULTS: At the end of the study, the groups showed no difference in cardiac output or MAP, but the volume balance (mL/kg BW) was significantly higher in the 0.9% NaCl group (346±90; P≤0.05) than in the other groups (6% HES130, 125±26; 6% HES200, 105±15; 10% HES130, 114±17; 10% HES200, 96±23). Creatinine clearance (mL/min) was significantly lower in the 6% HES200 (26±33) and 10% HES200 (15±18) groups compared to the 0.9% NaCl group (104±46; P≤0.05) but not in the HES 130 formulations (6% HES130: 64±51; 10% HES130: 58±38) at the end of the study.CONCLUSION: In this porcine two-hit shock model, treatment with 0.9% NaCl, HES 130/0.42 or HES 200/0.5 led to a similar maintenance of haemodynamic values. Despite this similar maintenance of the haemodynamic values, volume replacement with 6% and 10% HES 200/0.5 led to an accumulation of HES, higher colloid osmotic pressure and significantly reduced renal function after haemorrhagic and septic shock. These facts support the presumption that not the concentration but the degree of substitution and the molecular weight play a decisive role in HES-induced renal impairment.

We present phase field simulation results of the directional solidification of an Al[sbnd]Cu4wt% alloy followed by a holding stage during which the mushy zone solidifies in a static thermal gradient. During the holding stage, the initially dendritic morphology solidifies through the TGZM (Temperature Gradient Zone Melting) process, in accordance with recent in-situ X-ray measurements. This yields a planar solid/liquid interface that evolves towards a partial equilibrium where the liquid is homogeneous and the solid still shows a microsegregation pattern. A slow solid state diffusion then drives the subsequent evolution towards the final stationary state where chemical fluxes vanish. We study analytically the microsegregation in the solid, showing that TGZM has a major influence on its development during directional dendritic growth and on its evolution during the holding stage. Especially, we develop an expression for the concentration profile within a secondary dendrite arm during growth. We also develop theoretical arguments to determine the position in the thermal gradient of a transition region that separates the solid at partial equilibrium into two spatial domains. Close to the solid/liquid interface, the microsegregation exhibits a simple pattern resulting from a full remelting of the dendritic solid, while at lower temperatures the pattern is more complex and results from an only partial remelting. © 2016 Acta Materialia Inc.

Okuda J.,RWTH Aachen
European Journal of Inorganic Chemistry | Year: 2017

Abstract: A brief account of the discovery of ferrocene and a personal view of its significance are presented. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Baumann R.,RWTH Aachen
Journal of Exposure Science and Environmental Epidemiology | Year: 2017

Zinc- and copper-containing welding fumes increase systemic C-reactive protein (CRP). The aim of this study was to investigate the performance of the biomarkers serum amyloid A (SAA) and soluble vascular cell adhesion molecule-1 (VCAM-1) in this regard. Fifteen male subjects were exposed under controlled conditions to welding fumes containing either zinc, or copper, or copper and zinc for 6 h. Plasma samples were collected before, 6 and 24 h after start of exposure and biomarkers therein were measured by electrochemiluminescent assay. For each exposure, systemic concentrations of systemic SAA, but not VCAM-1, increased significantly at 24 h after exposure start compared with baseline (“copper only”: P=0.0005, “zinc only”: P=0.027, “copper and zinc”: P=0.001). SAA showed a wider range of concentrations than did CRP and its levels increased up to 19-fold after welding fume exposure. The recognition of copper as a potential harmful component in welding fumes, also independent from zinc, deserves further consideration. SAA might represent a new sensitive biomarker for potential subclinical sterile inflammation after inhalation of copper- and/or zinc-containing welding fumes. As elevations of CRP and SAA protein have both been linked to a higher risk for cardiovascular disease, these findings might particularly be important for long-term welders.Journal of Exposure Science and Environmental Epidemiology advance online publication, 8 February 2017; doi:10.1038/jes.2016.86. © 2017 The Author(s)

Khiem V.N.,RWTH Aachen | Itskov M.,RWTH Aachen
International Journal of Plasticity | Year: 2016

In this paper, a micromechanically based constitutive model capturing anisotropic stress softening in reinforced elastomers under quasi-static loading is presented. A novel spatial distribution function of polymer chains taking into account its deformation induced anisotropic alignment is proposed. By this means, the anisotropic network averaging over the unit sphere can be evaluated analytically. The anisotropic alignment of polymer chains introduces non-affine deformation in the model. Furthermore, the anisotropic evolution of the Mullins effect and hysteresis are also derived analytically, so that no numerical integration is applied here. The model includes very few physically motivated material parameters and demonstrates good agreement with multi-dimensional experimental data as well as with molecular dynamics simulations. © 2016 Elsevier Ltd.

Although microbubbles can boost the diagnostic value of ultrasonography (US), they are not routinely applied in clinical tumor diagnosis. This can be explained by the limited reproducibility of US examinations and the fact that single or few recorded image sections may not be representative of the entire tumor. Three-dimensional (3D) US may help to overcome these limitations. Therefore, Wang and coworkers applied a 3D matrix transducer to monitor response of colon cancer xenografts to antiangiogenic therapy with functional and molecular US imaging. It was shown that tumor response to therapy can be assessed early, precisely, and in high agreement with histologic fndings. © 2016 RSNA.

Nitride and oxy-nitride HPPMS coatings for the application in the plastics processing (Part 2). In the previous issue three oxy-nitridic hard coatings on CrAl-basis were investigated. These coatings were deposited by physical vapour deposition (PVD) as protective coatings against adhesive and abrasive wear in polymer extrusion. The coatings were developed using a variation of the oxygen content to investigate the influence of the chemical composition on the coating properties as well as composite properties between the coating and the coated tool. Following up on these findings this article will focus on the application oriented system properties of the three investigated coating systems towards the polycarbonate melt. Copyright © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Plamper F.A.,RWTH Aachen | Richtering W.,RWTH Aachen | Richtering W.,DWI Leibniz Institute for Interactive Materials
Accounts of Chemical Research | Year: 2017

Conspectus Microgels are macromolecular networks swollen by the solvent in which they are dissolved. They are unique systems that are distinctly different from common colloids, such as, e.g., rigid nanoparticles, flexible macromolecules, micelles, or vesicles. The size of the microgel networks is in the range of several micrometers down to nanometers (then sometimes called “nanogels”). In a collapsed state, they might resemble hard colloids but they can still contain significant amounts of solvent. When swollen, they are soft and have a fuzzy surface with dangling chains. The presence of cross-links provides structural integrity, in contrast to linear and (hyper)branched polymers. Obviously, the cross-linker content will allow control of whether microgels behave more “colloidal” or “macromolecular”. The combination of being soft and porous while still having a stable structure through the cross-linked network allows for designing microgels that have the same total chemical composition, but different properties due to a different architecture. Microgels based, e.g., on two monomers but have either statistical spatial distribution, or a core-shell or hollow-two-shell morphology will display very different properties. Microgels provide the possibility to introduce chemical functionality at different positions. Combining architectural diversity and compartmentalization of reactive groups enables thus short-range coexistence of otherwise instable combinations of chemical reactivity. The open microgel structure is beneficial for uptake-release purposes of active substances. In addition, the openness allows site-selective integration of active functionalities like reactive groups, charges, or markers by postmodification processes. The unique ability of microgels to retain their colloidal stability and swelling degree both in water and in many organic solvents allows use of different chemistries for the modification of microgel structure. The capability of microgels to adjust both their shape and volume in response to external stimuli (e.g., temperature, ionic strength and composition, pH, electrochemical stimulus, pressure, light) provides the opportunity to reversibly tune their physicochemical properties. From a physics point of view, microgels are particularly intriguing and challenging, since their intraparticle properties are intimately linked to their interparticle behavior. Microgels, which reveal interface activity without necessarily being amphiphilic, develop even more complex behavior when located at fluid or solid interfaces: the sensitivity of microgels to various stimuli allows, e.g., the modulation of emulsion stability, adhesion, sensing, and filtration. Hence, we envision an ever-increasing relevance of microgels in these fields including biomedicine and process technology. In sum, microgels unite properties of very different classes of materials. Microgels can be based on very different (bio)macromolecules such as, e.g., polysaccharides, peptides, or DNA, as well as on synthetic polymers. This Account focuses on synthetic microgels (mainly based on acrylamides); however, the general, fundamental features of microgels are independent of the chemical nature of the building moieties. Microgels allow combining features of chemical functionality, structural integrity, macromolecular architecture, adaptivity, permeability, and deformability in a unique way to include the “best” of the colloidal, polymeric, and surfactant worlds. This will open the door for novel applications in very different fields such as, e.g., in sensors, catalysis, and separation technology. © 2017 American Chemical Society.

In this work, new generalized interface models for gradient plasticity based on the dislocation density tensor are presented. The first one is a new generalized cohesive zone model which can be used for interface damage and delamination in gradient plasticity applications. The second one is a new grain boundary yield criterion with isotropic and kinematic hardening and a related flow rule, being formulated based on results from discrete dislocation simulations. The derivation starts from surface-related considerations, like in the work of Del Piero (2009), who starts with the virtual power of the external forces and then derives the principle of virtual power (Povp) rather than postulating it. Here, however, the formulation is carried out without using the notion of 'virtual power', although the derivation may as well be based on the Povp. Moreover, the derivation does not involve new micro force balance equations. In addition, the dislocation density tensor occurs rather as an outcome of the approach than as an ingredient. The discussion is closed by an example. © 2017 Elsevier Ltd.

Recent years have seen an increased application of small-scale uniaxial testing—microcompression—to the study of plasticity in macroscopically brittle materials. By suppressing fast fracture, new insights into deformation mechanisms of more complex crystals have become available, which had previously been out of reach of experiments. Structurally complex intermetallics, metallic compounds, or oxides are commonly brittle, but in some cases extraordinary, though currently mostly unpredictable, mechanical properties are found. This paper aims to give a survey of current advances, outstanding challenges, and practical considerations in testing such hard, brittle, and anisotropic crystals. Copyright © Materials Research Society 2017

Felderhof B.U.,RWTH Aachen
European Journal of Mechanics, B/Fluids | Year: 2017

Swimming at small Reynolds number of a collinear assembly of identical spheres immersed in an incompressible viscous fluid is studied on the basis of a set of equations of motion for the individual spheres. The motion of the spheres is caused by actuating forces and forces derived from a direct interaction potential, as well as hydrodynamic forces exerted by the fluid as frictional and added mass hydrodynamic interactions. The swimming velocity is deduced from the momentum balance equation for the assembly of spheres, and the mean power required during a period is calculated from an instantaneous power equation. Expressions are derived for the mean swimming velocity and the mean power, valid to second order in the amplitude of displacements from the relative equilibrium positions. Hence these quantities can be evaluated in terms of prescribed periodic displacements. Explicit calculations are performed for a linear chain of three identical spheres. © 2017 Elsevier Masson SAS

Dernehl C.,RWTH Aachen
2016 European Control Conference, ECC 2016 | Year: 2016

In this paper we propose a fully automatic technique to generate safety proofs for a given block diagram. Our method computes automatically Lyapunov functions for linear and polynomial systems within a block diagram. User defined safety constraints can be added to our verification algorithm, combining the reachable set of a system with sat modulo theory constraints to prove that all safety conditions are fulfilled. © 2016 EUCA.

Ziegler M.,RWTH Aachen
Procedia Engineering | Year: 2017

Geosynthetics are widely used for separation, protection, drainage, filtration and sealing. In addition, high-strength geogrids have been more and more successfully used in recent times for the construction of steep slopes and geogrid reinforced bridge abutments, the crossing of areas with soft soil by using geosynthetic encased sand columns and the bridging of areas susceptible to sinkholes. Particularly for the last case geosynthetics with additional features have been developed allowing a permanent monitoring of the deformations. The development of such intelligent geosynthetics with integrated chips and sensors for measuring strains, temperature or environmental conditions are by no means at its end. Geosynthetics of the future will be equipped with such additional functions enabling a permanent and non-destructive monitoring of structures built with geosynthetics. Anyhow, geogrid reinforcement constructions show significant advantages in terms of economic and ecological aspects against classical concrete structures. It is also well known from large-scale experiments and field tests that geosynthetic-reinforced constructions have a much higher bearing capacity than calculated and that the deformations are much lower than expected. Therefore, it is quite evident that the compound behavior of geosynthetic and soil is not yet completely understood. Recent research on this topic using large-scale triaxial- and biaxial- tests combined with a modern method of visualization of the movement of the soil particles tries to fill this gap.

BACKGROUND:: One important explanation for the detrimental effects of conventional mechanical ventilation is the biotrauma hypothesis that ventilation may trigger proinflammatory responses that subsequently cause lung injury. This hypothesis has frequently been studied in so-called one-hit models (overventilation of healthy lungs) that so far have failed to establish an unequivocal link between inflammation and hypoxemic lung failure. This study was designed to develop a one-hit biotrauma model. METHODS:: Mice (six per group) were ventilated for up to 7 h (positive end-expiratory pressure 2 cm H2O) and received 300 μl/h fluid support. Series_1: initial plateau pressures of 10, 24, 27, or 30 cm H2O. Series_2: ventilation with pressure release at 34 cm H2O and initial plateau pressure of 10, 24, 27, or 30 cm H2O. To study the significance of inflammation, the latter groups were also pretreated with the steroid dexamethasone. RESULTS:: Within 7 h, 20 of 24 mice ventilated with plateau pressure of 27 cm H2O or more died of a catastrophic lung failure characterized by strongly increased proinflammatory markers and a precipitous decrease in pulmonary compliance, blood pressure, and oxygenation. Pretreatment with dexamethasone reduced inflammation, but prolonged median survival time by 30 min. CONCLUSIONS:: Our findings demonstrate a sharp distinction between ventilation with 24 cm H2O that was well tolerated and ventilation with 27 cm H2O that was lethal for most animals due to catastrophic lung failure. In the former case, inflammation was benign and in the latter, a by-product that only accelerated lung failure. The authors suggest that biotrauma—when defined as a ventilation-induced and inflammation-dependent hypoxemia—is difficult to study in murine one-hit models of ventilation, at least not within 7 h. Copyright © by 2017, the American Society of Anesthesiologists, Inc. Wolters Kluwer Health, Inc. All Rights Reserved.

Schneider R.,RWTH Aachen
2016 IEEE 55th Conference on Decision and Control, CDC 2016 | Year: 2016

Based on the same centralized moving horizon estimator (CMHE) with a scalar regularization parameter, two different sensitivity-driven and partition-based moving horizon estimators (PMHEs) are presented and compared. Both are iterative and converge towards the optimum of the underlying CMHE, but their convergence properties are different. In this paper, we discuss the effects of various tuning parameters and the partitioning scheme on their convergence and illustrate these effects with numerical experiments. © 2016 IEEE.

Abraham E.,RWTH Aachen
Proceedings - 18th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing, SYNASC 2016 | Year: 2016

Satisfiability Checking is a relatively young research area, aiming at the development of efficient software technologies for checking the satisfiability of existentially quantified logical formulas. Besides the success story of SAT solving for propositional logic, SAT-modulo-theories (SMT) solvers offer sophisticated solutions for different theories. When targeting arithmetic theories, SMT solvers also make use of decision procedures rooted in Symbolic Computation. In this paper we give a brief introduction to SMT solving, discuss differences to Symbolic Computation, and illustrate the potentials and obstacles for embedding Symbolic Computation techniques in SMT solving on the example of the Cylindrical Algebraic Decomposition. © 2016 IEEE.

Berkholz C.,Humboldt University of Berlin | Grohe M.,RWTH Aachen
Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms | Year: 2017

In recent years, we have seen several approaches to the graph isomorphism problem based on generic mathematical programming or algebraic (Gröbner basis) techniques. For most of these, lower bounds have been established. In fact, it has been shown that the pairs of non-isomorphic CFI-graphs (introduced by Cai, Furer, and Immerman in 1992 as hard examples for the combinatorial Weisfeiler-Leman algorithm) cannot be distinguished by these mathematical algorithms. A notable exception were the algebraic algorithms over the field F2, for which no lower bound was known. Another, in some way even stronger, approach to graph isomorphism testing is based on solving systems of linear Diophantine equations (that is, linear equations over the integers), which is known to be possible in polynomial time. So far, no lower bounds for this approach were known. Lower bounds for the algebraic algorithms can best be proved in the framework of proof complexity, where they can be phrased as lower bounds for algebraic proof systems such as Nullstellensatz or the (more powerful) polynomial calculus. We give new hard examples for these systems: families of pairs of non-isomorphic graphs that are hard to distinguish by polynomial calculus proofs simultaneously over all prime fields, including F2, as well as examples that are hard to distinguish by the systems-of-linear-Diophantineequations approach. In a previous paper, we observed that the CFI-graphs are closely related to what we call group CSPs: constraint satisfaction problems where the constraints are membership tests in some coset of a subgroup of a cartesian power of a base group (Z2 in the case of the classical CFI-graphs). Our new examples are also based on group CSPs (for Abelian groups), but here we extend the CSPs by a few non-group constraints to obtain even harder instances for graph isomorphism. Copyright © by SIAM.

OBJECTIVE:: To evaluate (1) levels of the host-defense/antimicrobial peptide LL-37 in patients with trauma and hemorrhagic shock (HS) and (2) the effects of a synthetic host-defense peptide; Pep19-4LF on multiple organ failure (MOF) associated with HS. BACKGROUND:: HS is a common cause of death in severely injured patients. There is no specific therapy that reduces HS-associated MOF. METHODS:: (1) LL-37 was measured in 47 trauma/HS patients admitted to an urban major trauma center. (2) Male Wistar rats were submitted to HS (90?min, target mean arterial pressure: 27–32?mm Hg) or sham operation. Rats were treated with Pep19-4LF [66 (n = 8) or 333?μg/kg?·?h (n = 8)] or vehicle (n = 12) for 4 hours following resuscitation. RESULTS:: Plasma LL-37 was 12-fold higher in patients with trauma/HS compared to healthy volunteers. HS rats treated with Pep19-4LF (high dose) had a higher mean arterial pressure at the end of the 4-hour resuscitation period (79?±?4 vs 54?±?5?mm Hg) and less renal dysfunction, liver injury, and lung inflammation than HS rats treated with vehicle. Pep19-4LF enhanced (kidney/liver) the phosphorylation of (1) protein kinase B and (2) endothelial nitric oxide synthase. Pep19-4LF attenuated the HS-induced (1) translocation of p65 from cytosol to nucleus, (2) phosphorylation of IκB kinase on Ser, and (3) phosphorylation of IκBα on Ser resulting in inhibition of nuclear factor kappa B and formation of proinflammatory cytokines. Pep19-4LF prevented the release of tumor necrosis factor alpha caused by heparan sulfate in human mononuclear cells by binding to this damage-associated molecular pattern. CONCLUSIONS:: Trauma-associated HS results in release of LL-37. The synthetic host-defense/antimicrobial peptide Pep19-4LF attenuates the organ injury/dysfunction associated with HS. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

Otto T.,Dana-Farber Cancer Institute | Otto T.,RWTH Aachen | Sicinski P.,Dana-Farber Cancer Institute
Nature Reviews Cancer | Year: 2017

Cancer is characterized by uncontrolled tumour cell proliferation resulting from aberrant activity of various cell cycle proteins. Therefore, cell cycle regulators are considered attractive targets in cancer therapy. Intriguingly, animal models demonstrate that some of these proteins are not essential for proliferation of non-transformed cells and development of most tissues. By contrast, many cancers are uniquely dependent on these proteins and hence are selectively sensitive to their inhibition. After decades of research on the physiological functions of cell cycle proteins and their relevance for cancer, this knowledge recently translated into the first approved cancer therapeutic targeting of a direct regulator of the cell cycle. In this Review, we focus on proteins that directly regulate cell cycle progression (such as cyclin-dependent kinases (CDKs)), as well as checkpoint kinases, Aurora kinases and Polo-like kinases (PLKs). We discuss the role of cell cycle proteins in cancer, the rationale for targeting them in cancer treatment and results of clinical trials, as well as the future therapeutic potential of various cell cycle inhibitors. © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.

Herisanu I.T.,RWTH Aachen
Otology and Neurotology | Year: 2017

OBJECTIVE:: Psychotic disorders and intelligence deficiencies are no longer contraindications for cochlear implantation regarding the revised German guidelines from May 2012. This article aims to evaluate the outcome of patients with severe psychiatric comorbidities. Therefore the database of the Cochlear Implant Center of the University Hospital of Heidelberg was investigated. STUDY DESIGN:: Retrospective case review. METHODS:: We present three patients who received a cochlear implant (CI) despite a serious psychiatric disorder. Two were sent from psychiatrists asking if a CI was possible for their profound hearing loss. One patient had acoustic hallucinations and a recurrent depressive disorder, the other had a schizophrenic psychosis and a minor impairment of intelligence. The third patient had a recurrent depressive disorder, a posttraumatic stress disorder, a chronic pain disorder, and paranoid personality traits. We discuss the preoperative diagnosis, course of diseases, and psychosocial situation. RESULTS:: All three patients received a CI and rehabilitation in the Cochlear Implant Center of the University Hospital of Heidelberg. All three of them opted for a second implant and developed a good hearing outcome. Free field understanding of words in quite is for all three of them over 60% in the Freiburger monosyllable test with two implants, similar to nonpsychiatric patients’ results. No patient has acceptance problems. In the long run, no aggravation of the psychiatric diseases occurred. CONCLUSION:: With interdisciplinary evaluation, a cochlear implantation is possible in severely impaired psychiatric patients. For a good result the indication is to be discussed interdisciplinary. Copyright © 2017 by Otology & Neurotology, Inc. Image copyright © 2010 Wolters Kluwer Health/Anatomical Chart Company

While industrial NH3 synthesis based on the Haber-Bosch-process was invented more than a century ago, there is still no molecular catalyst available which reduces N2 in the reaction system N2/H2 to NH3. As the many efforts of experimentally working research groups to develop a molecular catalyst for NH3 synthesis from N2/H2 have led to a variety of stoichiometric reductions it seems justified to undertake the attempt of systematizing the various approaches of how the N2 molecule might be reduced to NH3 with H2 at a transition metal complex. In this contribution therefore a variety of intuition-based concepts are presented with the intention to show how the problem can be approached. While no claim for completeness is made, these concepts intend to generate a working plan for future research. Beyond this, it is suggested that these concepts should be evaluated with regard to experimental feasibility by checking barrier heights of single reaction steps and also by computation of whole catalytic cycles employing density functional theory (DFT) calculations. This serves as a tool which extends the empirically driven search process and expands it by computed insights which can be used to rationalize the various challenges which must be met. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

News Article | April 18, 2017
Site: www.newscientist.com

A squadron of miniature spacecraft has set off on an expedition to a little-known zone of Earth’s atmosphere. Riding an Atlas V rocket, they took off from Cape Canaveral in Florida at 1111 local time today, headed for the International Space Station. The 28 boxy satellites are part of QB50, an international mission to explore Earth’s lower thermosphere. Stretching from about 90 to 300 kilometres above ground level, this turbulent region is stirred from above by solar storms and flares, and from below by terrestrial weather. In its unpredictable moods it can scatter satellites and scramble GPS, so scientists would love to learn more about the gas and plasma up there. But this upper air is far too thin to support research planes or balloons, while still thick enough to drag down spacecraft in a matter of months. Ground-based observations are no substitute for measurements in situ. Although a few satellites have taken measurements on their way back down to Earth, “these are sparse data, with no continuity”, says QB50 project manager Davide Masutti at the von Karman Institute in Sint-Genesius-Rode, Belgium. This lack of information has given this region its nickname: the ignorosphere. The new mission will change that. Around 30 days after arrival at the ISS, a spring-loaded rack of CubeSats – small spacecraft made from off-the-shelf parts – will be manoeuvred out of an airlock, and one by one they will be pushed away. “We will have a string of pearls spaced out along the orbit,” says Masutti. The little satellites – most measuring 20 x 10 x 10 centimetres, and weighing a couple of kilograms – will soon be dragged downwards into Earth’s atmosphere. As they spiral through the thermosphere, they will measure the density and temperature of atoms, molecules, ions and electrons. For the first time this will give scientists simultaneous data from many points within the thermosphere, helping them to unravel its complexities. The instruments are standardised, but the satellites themselves have been built by teams of students at universities around the world, each with their own ideas. “Everybody has a totally different design,” says Masutti. A separate expedition party of eight CubeSats is due to be sent up by the Indian PSLV rocket, probably in May. They will not explore the lower thermosphere; instead, they will start at an altitude of 520 kilometres on an orbit that takes them over the poles and through some lively parts of the upper thermosphere, where charged particles swarm down along Earth’s magnetic field lines. Two CubeSats in this group have a different mission, testing out new technology for de-orbiting satellites at the end of their usable lives. One is the InflateSail, built at the University of Surrey in the UK. It will extend an inflatable boom and a sail that looks like a square umbrella, to increase drag and speed its descent. The other is Compass-2, built at RWTH Aachen University, Germany.

Huckelhoven R.,TU Munich | Panstruga R.,RWTH Aachen | Panstruga R.,Max Planck Institute for Plant Breeding Research
Current Opinion in Plant Biology | Year: 2011

Powdery mildew fungi represent a paradigm for obligate biotrophic parasites, which only propagate in long-lasting intimate interactions with living host cells. These highly specialized phytopathogens induce re-organization of host cell architecture and physiology for their own demands. This probably includes the corruption of basal host cellular functions for successful fungal pathogenesis. Recent studies revealed secretory processes by both interaction partners as key incidents of the combat at the plant-fungus interface. The analysis of cellular events during plant-powdery mildew interactions may not only lead to a better understanding of plant pathological features, but may also foster novel discoveries in the area of plant cell biology. © 2011 Elsevier Ltd.

Struchtrup H.,University of Victoria | Torrilhon M.,RWTH Aachen
Physics of Fluids | Year: 2013

The regularized 13 moment equations of rarefied gas dynamics are derived for a monatomic hard sphere gas in the linear regime. The equations are based on an extended Grad-type moment system, which is systematically reduced by means of the Order of Magnitude Method [H. Struchtrup, "Stable transport equations for rarefied gases at high orders in the Knudsen number," Phys. Fluids16(11), 3921-3934 (2004)]10.1063/1.1782751. Chapman-Enskog expansion of the final equations yields the linear Burnett and super-Burnett equations. While the Burnett coefficients agree with literature values, this seems to be the first time that super-Burnett coefficients are computed for a hard sphere gas. As a first test of the equations the dispersion and damping of sound waves is considered. © 2013 AIP Publishing LLC.

Jutz G.,RWTH Aachen | Van Rijn P.,RWTH Aachen | Van Rijn P.,University of Groningen | Santos Miranda B.,University of Groningen | Boker A.,RWTH Aachen
Chemical Reviews | Year: 2015

Protein structures such as ferritin in combination with synthetic as well as genetic alterations has proven to be highly interesting for the production of new materials. Ferritin describes a family of iron storage proteins with ubiquitous distribution among all life forms, with the notable exception of yeast and they are the most abundant members of the ferritin-like superfamily and may have developed from a rubrerythrin-like ancestor protein with two homologous pairs of antiparallel helices as main structural feature. The protein shell of mammalian ferritin is usually heterogeneous and consists of a mixture of two subunits of about 21 kDa, termed H for heavy (predominant in heart) and of about 19 kDa, termed L for light chain (predominant in liver), with around 55% amino acid homology for human H- and Lferritin. Apoferritin can be readily disassembled and reassembled by reducing the pH to a value as low as pH 2 and increasing it above pH 7, respectively. Holo-ferritin exhibits a remarkable affinity for anions and some nonferrous metal ions. Direct demineralization of the iron core in ferritins can be induced with strong Fe(III) chelators.

Mause S.F.,Institute for Molecular Cardiovascular Research | Mause S.F.,RWTH Aachen | Weber C.,Institute for Molecular Cardiovascular Research
Circulation Research | Year: 2010

Microparticles represent a heterogeneous population of vesicles with a diameter of 100 to 1000 nm that are released by budding of the plasma membrane and express antigens specific of their parental cells. Although microparticle formation represents a physiological phenomenon, a multitude of pathologies are associated with a considerable increase in circulating microparticles, including inflammatory and autoimmune diseases, atherosclerosis, and malignancies. Microparticles display an broad spectrum of bioactive substances and receptors on their surface and harbor a concentrated set of cytokines, signaling proteins, mRNA, and microRNA. Recent studies provided evidence for the concept of microparticles as veritable vectors for the intercellular exchange of biological signals and information. Indeed, microparticles may transfer part of their components and content to selected target cells, thus mediating cell activation, phenotypic modification, and reprogramming of cell function. Because microparticles readily circulate in the vasculature, they may serve as shuttle modules and signaling transducers not only in their local environment but also at remarkable distance from their site of origin. Altogether, this transcellular delivery system may extend the confines of the limited transcriptome and proteome of recipient cells and establishes a communication network in which specific properties and information among cells can be efficiently shared. At least in same cases, the sequential steps of the transfer process underlie complex regulatory mechanisms, including selective sorting (" packaging") of microparticle components and content, specificity of interactions with target cells determined by surface receptors, and ultimately finely tuned and signal-dependent release and delivery of microparticle content. © 2010 American Heart Association. All rights reserved.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENERGY.2009.8.1.1 | Award Amount: 8.47M | Year: 2010

Primary aluminium production industry is the worlds larger industrial consumer of energy and ranked among the most CO2 intensive industries. It also generates enormous quantities of wastes that further decrease the exergy efficiency of its production process. However, this industry is one of the most vital sectors from economic and social point of view, not only for EU but also for the entire world. In order to remain viable and competitive, primary aluminium industry has to operate in a smarter way, be more energy efficient and meet the environmental requirements of our times. This can be achieved only through radical new technologies and novel business strategies, which will enable the industry to maintain its competitiveness and fasten its viability in the worlds markets, and explore new business opportunities. The main goal of this project is to provide primary aluminium industry with green innovative technological and economical solutions, focusing on the: (i) significant improvement of energy and exergy efficiencies of the production process; (ii) substantial reduction of GHG emissions; and (iii) complete elimination of the solid wastes. In order to achieve this goal within the project, novel technologies for the reduction of alumina to aluminium and the complete utilization of the red mud will be demonstrated and validated in pilot-scale. These technologies are energy-efficient and environmental-friendly, ensuring the competitiveness of the industry. A site optimization study of the new industry, integrating the novel technologies, is expected to achieve further reduction of energy and CO2 emissions and improve the energy and exergy efficiency of the whole process. It is aimed that the novel technologies will play a key-role on the sustainability, competitiveness and viability of primary aluminium production industry, so as to render it a leader industry for energy-efficient technologies and products in Europe and worldwide.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: GC.SST.2012.2-2. | Award Amount: 16.63M | Year: 2012

The CONVENIENT project targets a 30% reduction of fuel consumption in vehicles for long-distance freight transport by developing an innovative heavy-truck archetype featuring a suite of innovative energy-saving technologies and solutions. From the customer viewpoint, fuel efficiency is top priority because of its significant impact in terms of cost (in the EU, fuel represents about 30% of the Total Operating Costs for a 40-ton tractor-semitrailer combination). Responding to this challenge, the objective of CONVENIENT is to achieve complete vehicle energy management by proposing highly innovative solutions for improved efficiency and enhanced integration of components (currently designed independently) which will be developed, integrated and evaluated directly on validator vehicles, including: innovative energy efficient systems, including hybrid transmission, electrified auxiliaries, dual level cooling, parking HVAC energy harvesting devices, like photovoltaic solar roof for truck and semitrailer; advanced active and passive aerodynamics devices for the truck and for the semitrailer: an Holistic Energy Management system at vehicle level; a Predictive Driver Support to maximize the energy saving benefits. a novel Hybrid Kinetic Energy Recovery System for the semitrailer. The most relevant and novel aspect of CONVENIENT is represented by the holistic approach to on-board energy management, considering the tractor, semi-trailer, driver and the mission as a whole. The CONVENIENT Consortium, which comprises three major EU truck manufacturers, ten Tier 1/2 suppliers, and a network of nine research centres and Universities, representing European excellence in the field of long distance transport R&D, is uniquely well-qualified with respect to the project scope and the highly ambitious target of achieving 30% gains in vehicle efficiency.

Agency: European Commission | Branch: FP7 | Program: CPCSA | Phase: ICT-2013.9.9 | Award Amount: 74.61M | Year: 2013

This Flagship aims to take graphene and related layered materials from a state of raw potential to a point where they can revolutionize multiple industries from flexible, wearable and transparent electronics, to new energy applications and novel functional composites.\nOur main scientific and technological objectives in the different tiers of the value chain are to develop material technologies for ICT and beyond, identify new device concepts enabled by graphene and other layered materials, and integrate them to systems that provide new functionalities and open new application areas.\nThese objectives are supported by operative targets to bring together a large core consortium of European academic and industrial partners and to create a highly effective technology transfer highway, allowing industry to rapidly absorb and exploit new discoveries.\nThe Flagship will be aligned with European and national priorities to guarantee its successful long term operation and maximal impact on the national industrial and research communities.\nTogether, the scientific and technological objectives and operative targets will allow us to reach our societal goals: the Flagship will contribute to sustainable development by introducing new energy efficient and environmentally friendly products based on carbon and other abundant, safe and recyclable natural resources, and boost economic growth in Europe by creating new jobs and investment opportunities.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: SST.2008.1.1.4. | Award Amount: 25.04M | Year: 2010

The Project aims to develop new powertrain concepts able to give a substantial contribution to the achievement of a 50% CO2 reduction (based on 2005 figures) for passenger cars and light-duty vehicles for the new vehicle fleet in 2020. In particular, the research target on spark ignited (SI) engines powered vehicles is to achieve 40% lower CO2 emissions with respect to the 2005 values and 20% lower CO2 emission than the 2005 level for compression ignition (CI) engine powered vehicles. The objective includes also the target of near-zero emission levels (better than EURO 6) maintained during the useful life of the engines and keeping into account real life emissions, in line with the intention to amend the test procedures in emission legislation in view of real life emissions. Three different concepts will be investigated and implemented: - ultradownsizing gasoline engine integrating VVA, advanced turbocharging and Direct Injection; - two-stroke downsized diesel engine integrating HCCI and low temperature combustion modes; - combined combustion system based on Compression Ignited engine dedicated to new fuel formulation. Transversal supporting activities will be integrated for evaluating and assessing: advanced simulation methodologies for powertrain integration, advanced approaches for friction reduction (design solutions, coatings and surface treatments, lubricants), PEMS methodologies for real world emission analysis.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: FoF-ICT-2013.7.1 | Award Amount: 21.66M | Year: 2013

The importance of advanced simulation to the competitiveness of both large and small companies is well established. The principal objective of Fortissimo is to enable European manufacturing, particularly small to medium enterprises (SMEs), to benefit from the efficiency and competitive advantage inherent in the use of simulation. However, the simulation of, for example, high-pressure gas cylinders, the moulding of plastics or the thermodynamic properties of hazardous materials requires enormous computing power and specialised software tools and services. Generally, large companies, which have a greater pool of skills and resources, find access to advanced simulation easier than SMEs which can neither afford expensive High Performance Computing equipment nor the licensing cost for the relevant tools. This means that SMEs are not able to take advantage of advanced simulation, even though it can clearly make them more competitive. The goal of Fortissimo is to overcome this impasse through the provision of simulation services running on a cloud infrastructure making use of High Performance Computing systems also making appropriate skills and tools available in a distributed, internet-based environment.\n\nFortissimo will make advanced simulation more easily accessible, particularly to SMEs, through the realisation of a one-stop shop where hardware, expertise, applications, visualisation and tools will be easily available and affordable on a pay-per-use basis. In doing this it will create and demonstrate a sustainable commercial ecosystem where actors at all levels in the value chain can realise sufficient commercial benefit to enable that ecosystem to persist independently of EU funding and continue to provide affordable services to manufacturing industry, particularly SMEs.\n\nFortissimo will be driven by end-user requirements where (~50) business-relevant application experiments will be used to develop, test and demonstrate both the infrastructure and the one-stop pay-per-use shop. The project participants represent all actors in the value chain. Not only will Fortissimo contribute to the increased competitiveness of European manufacturing industry through the innovative infrastructure that it will develop and test, but it will create commercial opportunities for European Independent Software Vendors, as well as for service and High Performance Computing infrastructure providers, through the creation of a new market for their products and services. Fortissimo places considerable emphasis on the exploitation of opportunities at all levels of the value chain ranging from the end-user to the High Performance Computing infrastructure provider.\n\nFortissimo involves 1,132 months of effort, a total cost of 21.7m and EC funding of 16m over a duration of three years, commensurate with achieving its ambitious goals.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-23-2014 | Award Amount: 4.12M | Year: 2015

Disaster scenarios, like the Fukushima nuclear accident, clearly show that the capabilities of todays disaster response robots are not sufficient for providing the needed support to rescue workers. The CENTAURO project aims at development of a human-robot symbiotic system where a human operator is telepresent with its whole body in a Centaur-like robot, which is capable of robust locomotion and dexterous manipulation in the rough terrain and austere conditions characteristic of disasters. The CENTAURO robot will consist of a four-legged basis and an anthropomorphic upper body and will be driven by lightweight, compliant actuators. It will be able to navigate in affected man-made environments, including the inside of buildings and stairs, which are cluttered with debris and partially collapsed. The Centauro system will be capable of using unmodified human tools for solving complex bimanual manipulation tasks, such as connecting a hose or opening a valve, in order to relieve the situation. A human operator will control the robot intuitively using a full-body telepresence suit that provides visual, auditory, and upper-body haptic feedback. Rich sensors will provide the necessary situation awareness. Robot percepts and suggested actions will be displayed to the operator with augmented reality techniques. For routine manipulation and navigation tasks, autonomous robot skills will be developed. This will allow for taking the operator partially out of the control loop, which will be necessary to cope with communication latencies and bandwidth limitations and to reduce the operator workload. A series of increasingly complex tests with corresponding evaluation criteria will be devised from end-user requirements to systematically benchmark the capabilities of the developed disaster response system.

Agency: European Commission | Branch: FP7 | Program: NOE | Phase: ICT-2007.3.4 | Award Amount: 5.58M | Year: 2008

Due to technology limitations, the domain of high-performance processors is experiencing a radical shift towards parallelism through on-chip multi-cores and chip customization leading to heterogeneous multi-core systems. Furthermore, the commodity market, the supercomputing market and the embedded market are increasingly sharing the same challenges, leading to convergence of the three markets.\n\nThe main challenges for the future high-performance embedded systems have been documented in the HiPEAC roadmap (http://www.HiPEAC.net/roadmap), which forms the basis of the HiPEAC strategic research agenda. \n\nThe goal of the HiPEAC Network of Excellence is (i) to join forces in Europe to collectively work on the HiPEAC strategic research agenda, (ii) to realize European excellence in computing architectures, system software and platforms to enable the development of new applications, and (iii) to allow European companies to achieve world-leading positions in computing solutions and products.\n\nIn order to reach that goal, HiPEAC (a) will stimulate mobility between partners (internships, sabbaticals, research visits, cluster meeting), (b) will coordinate and steer research in 9 research clusters: (i) Multi-core architecture, (ii) Programming models and operating systems, (iii) Adaptive compilation, (iv) Interconnects, (v) Reconfigurable computing, (vi) Design methodology and tools, (vii) Binary translation and virtualization, (viii) Simulation platform, (ix) Compilation platform, and (c) will spread excellence by running the HiPEAC conference, the ACACES summer school, the HiPEAC journal, a newsletter, a website, seminars, technical reports, workshops, and awards.\n\nThis program of activities will lead to the permanent creation of a solid and integrated virtual centre of excellence consisting of several highly visible departments, and this virtual centre of excellence will have the necessary critical mass to really make a difference for the future of computing systems i

Agency: European Commission | Branch: H2020 | Program: IA | Phase: FoF-09-2015 | Award Amount: 6.31M | Year: 2015

ReconCell develops a new type of robot workcell, its required process infrastructures and the economic framework for automated robot assembly, especially designed for the needs of SMEs. SMEs would benefit from robotic automation, but often cannot use it due to set-up & maintenance complexity. This requires expert knowledge and time for configuration and programming, which is too costly for them. Robotic automation is, thus, normally economically infeasible for SMEs, especially for small batch sizes. ReconCell develops an easy to (re-)configure and (re-)program workcell, making robot solutions commercially viable even for small batch sizes (~1000 units) by reducing set-up & maintenance effort substantially. Specifically, the ReconCell System is based on a layered concept where we start together with the customer with business modelling the planned product assembly based on the ReconCell System to assess its economic viability and provide decisive Key Performance Indicators (KPIs). On approval, the next layer of the ReconCell System implements assembly with automated testing in simulation. Here we use reconfigurable hardware elements to design the required workcell layout and assembly processes. After verification, product assembly takes place in the real workcell under machine vision-based monitoring and novel force-based control of execution to assure product quality using the KPIs. We demonstrate the capabilities of the layered ReconCell System on three real use cases provided by the SMEs of our consortium and two more use cases, established through an open call. In addition, the consortium has started to establish a network of potential ReconCell users to disseminate information about ReconCell technologies to all actors in the value chain, and to raise awareness about the possibilities of automated robot assembly in SMEs. The final aim is to establish a company that commercializes the workcell and associated technologies developed in the ReconCell project.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.3.3 | Award Amount: 2.70M | Year: 2008

Characteristic for embedded systems is that they have to meet a multitude of quantitative constraints. These constraints involve the resources that a system may use (computation resources, power consumption, memory usage, communication bandwidth, costs, etc.), assumptions about the environment in which it operates (arrival rates, hybrid behaviour), and requirements on the services that the system has to provide (timing constraints, QoS, availability, fault tolerance, etc.). Model-Driven Development (MDD) is a new software development technique in which the primary software artifacts are models providing a collection of views. Existing MDD tools for real-time embedded systems are rather sophisticated in handling functional requirements but their treatment of quantitative constraints is still very limited. Hence MDD will not realise its full potential in the embedded systems area unless the ability to handle quantitative properties is drastically improved. The objective of Quasimodo is to develop theory and techniques for handling quantitative (e.g. real-time, hybrid and stochastic) constraints in model-driven development of real-time embedded systems. More specifically, the project aims at: 1. Improving the modelling of diverse quantitative aspects of embedded systems. 2. Providing a wide range of powerful techniques for analysing models with quantitative information and for establishing abstraction relations between them. 3. Generating predictable code from quantitative models. 4. Improving the overall quality of testing by using suitable quantitative models as the basis for automatically generating sound and correct test cases. In order to demonstrate the usefulness of our techniques, we will apply them to several complex industrial case studies, and provide tool components that support quantitative modelling, analysis, implementation and testing of embedded systems.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENERGY.2009.3.3.1 | Award Amount: 36.65M | Year: 2010

The development and implementation of bio-refinery processes is an absolute necessity and the key to meet the vision towards bio-based economy. The EuroBioRef concept is an integrated, sustainable and diversified bio-refinery involving all biomass value chain stakeholders. The latter will allow large-scale research, testing, optimisation and demonstration of processes in the production of a wide range of products with the dual aim to use all fractions of various biomasses and exploit their potential to produce the highest value possible in an eco-efficient and sustainable way. Moreover, the project attempts to overcome the efforts fragmentation of the whole biomass value chain requiring greater networking, coordination and cooperation among a large variety of actors from biochemical and chemical industry, SMEs, scientific knowledge chain, and European organisations. The new concept will adopt a flexible and a modular process design adapted to large- but also small-scale production units easier to install in various European areas. The overall efficiency of this approach will clearly exceed existing pathways and will consider sustainable options in order to: - Produce and use a high diversity of sustainable biomasses adapted for European regions - Produce high specific energy bio-jet fuels (42 MJ/kg) - Produce multiple products (chemicals, polymers, materials) in a flexible and optimised way that take advantage of the differences in biomass components and intermediates - Improve cost-efficiency by 30% through improved reaction and separation effectiveness, reduced capital investments, improved plant and feedstock flexibility, reduction of production time and logistics - Reduce by 30% the energy - Produce zero waste and rationalise use of raw materials The impact of the project in terms of environment, social and economic benefits is important and could give a serious advantage for European bio-industry.

Agency: European Commission | Branch: FP7 | Program: NOE | Phase: ICT-2007.1.1 | Award Amount: 9.17M | Year: 2008

NEWCOM\\ is the acronym of a proposed Network of Excellence in Wireless COMmunications, submitted to Call 1 of the VII Framework Programme under the Objective ICT-2007.1.1: The Network of the Future, mainly in its target direction Ubiquitous network infrastructure and architectures. The current proposal draws inspiration, shape/form, and substantive direction from its successful predecessor, the NoE NEWCOM, which was approved and funded by the EC for 36 months starting March 1st, 2004 and ending February 28, 2007. At the same time, NEWCOM\\ aspires to inject new vision, expanded roles, ever-higher degrees of research integration, and a definitive roadmap to financial security for the long-term life of this undertaking in the European research and higher-learning space. The core concept of NEWCOM\\ is that of an NoE of medium size, greatly reduced from the initial NEWCOM Consortium, formed by keeping the most committed and performing partners, exploiting the successful integration tools that NEWCOM designed and activated, and which is created for the purpose of scientifically addressing medium/long term, complex, interdisciplinary, fundamental research problems in the field of wireless networks, focused towards identifying, posing in the right modelling perspective, and at least partially characterizing the information-communication theoretical limits. Its main objectives are: Identify a selective set of scenarios, Define suitable performance measures that take into account the wireless channel nature, Perform a detailed analysis of the main theoretical results available, Evaluate information-theoretical bounds on the achievable performance, Design and analyze transmitting/receiving algorithms and protocols in order to approach those limits, Analyze implementation aspects of the above algorithms in flexible, energy-aware user terminals, Output the major findings into an integrated simulation library, Enhance the already good cooperation level among research

Agency: European Commission | Branch: FP7 | Program: NOE | Phase: ICT-2011.3.4 | Award Amount: 3.81M | Year: 2012

The proposed HiPEAC network of excellence is a follow-up of an existing network and wants (i) to steer and to increase the European research in computing systems; (ii) to improve the quality of the European computing systems research, and (iii) to create a visible and integrated pan-European community in computing systems. The network is structured along four programs. The membership program aims at growing the network. It will focus on the creation of a vibrant industrial membership, and it will reach out to the companies and academics in the new member states. It wants to increasingly organize events in new member states. The mobility program aims at bringing the partners and the members closer together. The mobility program supports two types of mobility: (i) exchanges of one to three months like internships, collaboration grants, mini-sabbaticals, and (ii) public networking events like computing systems weeks, sometimes collocated with other events (project meetings, conference, ...). The research coordination program aims at coordinating the joint research between the HiPEAC members. A tangible result of the research coordination is the bi-annual HiPEAC vision. It also wants to support the European low-power industry by promoting their platform ecosystem and it wants to proactively prepare the HiPEAC community for the impact of technological evolutions on computing systems (like photonics, new memory types, ...). It also runs a set of thematic workgroups on the different technical challenges and solutions from the HiPEAC roadmap. The visibility program manages all the public activities of the network such as the conference, the summer school, the website, the newsletter, the award program, the dissemination of research results, ... It wants (i) to proactively approach the specialized press, (ii) to grow the conference into a much bigger event, (iii) to make the HiPEAC institutions more attractive for top talent by creating a job portal.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.3.7 | Award Amount: 3.70M | Year: 2008

The focus of the project MULTIFORM is on the integration and the interoperation of tools and methods based on different modelling formalisms in order to make a significant step towards integrated coherent tool support for the design of large complex controlled systems from the first concept to the implementation and further on over their entire life cycle.By addressing the issue of multi-level multi-formalism control systems modelling and design, this project represents a definite advance over the traditional approach pursued by the control community that focuses solely on the design of control algorithms and, to some extent, their interaction with communication protocols. The multi-formalism approach pursued here reflects the heterogeneous nature of the functionality and of the implementation of controlled systems.The key contribution of the project towards the goal of integrated model-based control systems design is the connection of tools that support the design of different layers of the control hierarchy and on different levels of abstraction. Integration of tools is pursued both along the axes of re-use and consistency of models and data generated in the design process and of feedback and feedforward of results between different levels of abstraction addressed by tools that are based on different formalisms.The project MULTIFORM will address the following issues:\tInterchange formats between different tools\tIntegrated specification and synthesis of logic controllers\tNew ways of connecting techniques for analysis and design that are based on different levels of abstraction\tIntegration of the tools into a common framework\tApplication of multi-formalism analysis and design to challenging real-world case studies.

Agency: European Commission | Branch: FP7 | Program: CSA | Phase: ICT-2007.1.1 | Award Amount: 1.87M | Year: 2008

The EIFFEL Support Action forms a structure addressing the challenges of the Future Internet and the networked society of the future as a whole. Its foundations lie in the EIFFEL think tank formed in July 2006 from a group of individual researchers from both academia and industry, facilitated by the European Commission. Despite being highly successful in its operation, the current EIFFEL think tank cannot grow to be the representative body it should be without some organisational support. This proposal leverages the success of EIFFEL initiative by proposing a Support Action to provide the mechanisms and infrastructure that can strengthen the link between explorative and evolutionary research towards Future Networked Society in Europe.\n\nThe objectives of this Support Action are to create momentum, build cohesion and support the research, governance and policy communities by providing the European discussion forum and road mapping service that will facilitate the creation of relevant initiatives and give Europe leadership in the creation of the Future Networked Society. The project will be organized around a number of Technical Areas (TAs) focusing on technological, societal, regulatory and policy-related questions, and will attract key persons to lead discussions and will ensure the involvement of key participants for each of the main TAs.\n\nThe project will arrange two annual meetings for EIFFEL Initiative as a whole (with 25-50 participants) and a smaller number of ad hoc meetings as needed. These meetings will provide a forum for evaluating exploratory research ideas and for connections to relevant infrastructure efforts worldwide. With these tools the EIFFEL Support Action will stimulate discussion on fundamental issues of the Future Internet and build synergies between various research areas involved - including policy and regulatory requirements - in the interest of bringing Europe to the forefront of Future Internet research.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2013.5.2 | Award Amount: 4.55M | Year: 2013

Regional anaesthesia (RA) has been used increasingly during the past four decades. This is addressed to the perceived advantages of reduced postoperative pain, earlier mobility, shorter hospital stay, and significantly lower costs. The performance of regional anaesthesia necessitates blocking the peripheral nerves by local injection of anaesthetic. Clinically this is achieved by the insertion of the injection needle close to the peripheral nerve, which is visualized with ultrasound and the proximity of the needle to the nerve is assessed with an electric nerve stimulator. However, it is a subtle technique and requires good theoretical, practical, and non-cognitive skills to allow trainees to achieve confidence in performing regional anaesthesia and to keep complications to a minimum. Current training methods for regional anaesthesia include cadavers, video teaching, ultrasound guidance, and simple virtual patient modelling. These techniques have limited capabilities and do not consider individual anatomy. The Virtual Physiological Human (VPH) creates the possibility to generate patient-specific computer models and apply them to RA procedures. The goal of this project is to increase the application, the effectiveness and the success rates of RA and furthermore the diffusion of the method into a broader clinical use through the developmentof patient-specific VPH models for anaesthesia. We aim at developing two independent but complementary systems, one system for training and one for guidance: a patient-specific Regional Anaesthesia Simulator (RASim) enhanced with ultrasound guidance and a Regional Anaesthesia Assistant (RAAs), which will assist the physicians to localize the nerve during the actual procedure. The RASimAs project will combine both, offering the possibility of training in the regional anaesthesia technique during the training phase of the physician and providing assistance during the clinical application of regional anaesthesia at later stages.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2013.8.1 | Award Amount: 4.40M | Year: 2013

CREATIF provides the CCI with a creative experience collaborative tool consisting of intuitive software design tools coupled to a digital dispenser printer allowing them to create bespoke smart fabrics by printing. The design tools consist of software to collaboratively design, layout, visualise and simulate smart fabrics which are then produced using a dispenser printer; conventional fabrics are functionalised by printing active electronic inks. Visualisation and simulation will interact in the collaborative design process with the senses of sight (through a monitor image), hearing (through Skype and by the smart fabric function of sound emission from the PC speakers) and touch (through the use of touch screens for design and the simulation of the feel of the fabric and the feeling of being touched on a haptic PC screen). CREATIF offers to the CCI the ability to transform everyday fabrics into knowledge intensive smart fabric based creations incorporating a high level of intellectual creative content, by mass customisation of basic templates, or in one off designs. The consortium consists of a design software developer (G-Soft), a university specialised in fabric machine design (ITA), a university with world leading expertise in creating smart fabrics by printing (UoS), a creative design SME (Diffus), an SME, active in design-led building\nstructures and architecture (BASE), a large company active in architecture and creative design (ZHA) and an SME specialised in advanced inkjet printers (Ardeje). We demonstrate the creative experience tools use in a real environment by producing, within CREATIF, three advanced smart fabric prototypes (for interactive light emission, interactive colour change and sound emission/touch) and apply them in two applications relevant to the CCI: an interactive, modular blind and exhibition stand. These directly target the CCI of design, advertising and architecture although the collaborative tool impacts any CCI using fabrics.

Agency: European Commission | Branch: FP7 | Program: MC-ITN | Phase: PEOPLE-2007-1-1-ITN | Award Amount: 4.65M | Year: 2008

The mission of HIERARCHY is to train and educate young scientist in the rapidly developing field of nanosciences, in particular hierarchical self-assembly. The training programme educates early stage and experienced researches in many aspects of this highly interdisciplinary field, such as theory, materials chemistry and biochemistry, advanced characterisation techniques, physics and commercial device development. In addition, the training programme will address non-scientific issues, important for the career development of young scientists, e.g. communication and presentation skills, IPR and entrepreneurial skills, ethical issues, language enhancement and cultural awareness. The training takes place on a Network level and also locally at the host institutions. HIERARCHYs training programme will deliver versatile individuals with a broad scientific knowledge, ready to pursue a successful career in the European industry or academia. The interdisciplinary research training is centralised around the novel concept of hierarchical assembly in controllable matrices. This concept exploits liquid crystalline media as controllable matrices for programmed self-organisation, which goes far beyond the possibilities of currently employed techniques. A liquid crystal matrix in combination with a variety of simultaneously or sequentially applied external stimuli will yield a unique toolbox to build functional macroscopic structures with nanometer control. Leading European laboratories in soft condensed matter and solid state matter will work towards new paradigms in nanosciences. HIERARCHYs intention towards application of the designed structures, illustrated by the presence of three industrial partners in the consortium, is an important step towards commercialisation of nanosciences in Europe. With Europes desire to become the major player in the area of nanosciences, valorisation of developed technology is a key lesson for Europes new generation of nanoscientists.

Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2014-ETN | Award Amount: 3.72M | Year: 2014

To tackle its (critical) raw material dependency, Europe needs comprehensive strategies based on sustainable primary mining, substitution and recycling. Freshly produced flows and stocks of landfilled industrial residues such as mine tailings, non-ferrous slag and bauxite residue (BR) can provide major amounts of critical metals and, concurrently, minerals for low-carbon building materials. The European Training Network for Zero-Waste Valorisation of Bauxite Residue (REDMUD) therefore targets the vast streams of new and stockpiled BR in the EU-28. BR contains several critical metals, is associated with a substantial management cost, whereas spills have led to major environmental incidents, including the Ajka disaster in Hungary. To date, zero-waste valorisation of BR is not occurring yet. The creation of a zero-waste BR valorisation industry in Europe urgently requires skilled scientists and engineers, who can tackle the barriers to develop fully closed-loop environmentally-friendly recovery flow sheets. REDMUD trains 15 researchers in the S/T of bauxite residue valorisation, with emphasis on the recovery of Fe, Al, Ti and rare earths (incl. Sc) while valorising the residuals into building materials. An intersectoral and interdisciplinary collaboration of EU-leading institutes and scientists has been established, which covers the full value chain, from BR to recovered metals and new building materials. Research challenges include the development of efficient extraction of Fe, Al, Ti and rare earths (incl. Sc) from distinct (NORM classified) BRs and the preparation of new building materials with higher than usual Fe content. By training the researchers in pyro-, hydro- and ionometallurgy, electrolysis, rare-earth extraction and separation technology, inorganic polymer and cement chemistry, Life Cycle Assessment (LCA), NORM aspects and characterisation, they become the much needed scientists and engineers for the growing European critical raw materials industry.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.4.2 | Award Amount: 4.49M | Year: 2011

Online educational repositories of video lectures are rapidly growing on the basis of increasingly available and standardised infrastructure. A well-known example of this is the VideoLectures web portal, a free and open access educational video lectures repository, and a major player in the development of the widely used Opencast Matterhorn platform for educational video management. As in other repositories, transcription and translation of video lectures in VideoLectures is needed to make them accessible to speakers of different languages and to people with disabilities. However, also as in other repositories, most lectures in VideoLectures are neither transcribed nor translated because of the lack of efficient solutions to obtain them at a reasonable level of accuracy. The aim of transLectures is to develop innovative, cost-effective solutions to produce accurate transcriptions and translations in VideoLectures, with generality across other Matterhorn-related repositories. Our starting hypothesis is that there is only a relatively small gap for the current technology on automatic speech recognition and machine translation to achieve accurate enough results in the kind of audiovisual object collections we are considering. To close this gap, TL will follow two main research lines. First, we will study how to better deal with object variability by massive adaptation of general-purpose models from available lecture-specific knowledge. Second, as we think that accurate enough results are unlikely to be obtained with fully automatic methods alone, we will explore how to better reach the desired levels of accuracy by intelligent interaction with users. On the other hand, it is our goal not end up with a system prototype that is only evaluated at the lab and can hardly be used in real-life settings. Instead, we will develop tools to work with Matterhorn, and thus we will be able to evaluate them in a real-life setting.

EDA-EMERGE aims to train a new generation of young scientists in the interdisciplinary techniques required to meet the major challenges in the monitoring, assessment and management of toxic pollution in European river basins considering the enormous complexity of contamination, effects and cause-effect relationships. By integrating innovative mode-of-action based biodiagnostic tools including in vitro tests, transgenic organisms and omics techniques with powerful fractionation and cutting edge analytical and computational structure elucidation tools, a new generation of effect directed analysis (EDA) approaches will be developed for the identification of toxicants in European surface and drinking waters. Innovative method development by young researchers at major universities, research centres and private companies will be closely interlinked with a joint European demonstration program and higher tier EDA and extensive training courses. EDA-EMERGE ESRs will learn to organise and run international and interdisciplinary sampling and monitoring campaigns and benefit from the expertise of one of the most experienced private companies in this field. Strong networking between academia, the private sector and leading regulators in the field of river basin management and pollution management ensures the relevance of the research for practice and excellent employment opportunities for EDA-EMERGE ESRs. The combination of cutting edge science with training in multiple complementary (soft) skills offered with a strong emphasis on commercial exploitation and media competence will further enhance employability of well-trained ESRs not only in research and academia but far beyond. An internationally composed advisory board will introduce new perspectives of monitoring, assessment and management of emerging pollutants within and outside of Europe.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.4.3 | Award Amount: 8.50M | Year: 2009

ROLEs cross-disciplinary innovations will deliver and test prototypes of highly responsive TEL environments, offering breakthrough levels of effectiveness, flexibility, user-control and mass-individualisation. Our work also advances the state-of-the-art in human resource management; self-regulated and social learning; psycho-pedagogical theories of adaptive education and educational psychology; service composition and orchestration; and the use of ICT in lifelong learning. Significant benefits arise for learners, their communities, employers, TEL developers and society.\nROLE offers adaptivity and personalization in terms of (1) content and navigation and (2) the entire learning environment and its functionalities. This approach permits individualization of the components, tools, and functionalities of a learning environment, and their adjustment or replacement by existing web-based software tools. Learning environment elements can be combined to generate (to mashup) new components and functionalities, which can be adapted by lone learners or collaborating learners to meet their own needs and to enhance the effectiveness of their learning. This empowers each user to generate new tools and functions according to their needs, and can help them to establish a livelier and personally more meaningful learning context and learning experience.\nROLEs generic framework uses an open source approach, interoperable across software systems and technology. Hence any tool created by an individual is available from a pool of services and tools to all learners via the internet, no matter which learning environment, operating system, or device they use, and which subject matter they learn.\nThe consortium consists of well-renown experts covering all required pedagogical and technical competencies. Respective activities have been defined to bring the results of ROLE to the targeted international markets in higher education and corporate training.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.1.1 | Award Amount: 4.36M | Year: 2008

The project aims at provisioning a ubiquitous wireless solution to reach bit rates higher than 100Mbps with peak throughputs higher than 1Gbps, based on Reconfigurable OFDMA Cooperative Networks enabled by agile spectrum use (ROCKET). While increasing peak rates is a natural must-do for new standards, providing homogeneous high rate coverage is equally important as it guarantees a constant user experience over the whole served area and is the key enabler to a higher average spectral efficiency of the system. Those goals are inline with the IMT-Advanced requirements described in [ITU-R M1645] and match the requirements of the IEEE 802.16 Task Group m (TGm) for Advanced Air Interface.\n\nIn order to guarantee a strong focus and efficiency in the project, we propose to limit the scope of our investigations to two questions which we believe will be at the centre of future IMT-advanced system design:\n1. How can we increase the bandwidth and make the whole system benefit from it?\n2. How can we increase system spectral efficiency and provide ubiquitous high-rate coverage?\n\nThose questions are addressed by devising methods for improved spectrum usage, advanced multiuser cooperative transmission and ultra-efficient MAC design. Providing inputs to standardization bodies, generating IPR and demonstrating capabilities of some algorithms on a test-bed are the way the project plans to have actual impact.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.8.1 | Award Amount: 12.60M | Year: 2012

Learning Layers develops a set of modular and flexible technological layers for supporting workplace practices in SMEs that unlock peer production and scaffold learning in networks of SMEs, thereby bridging the gap between scaling and adaptation to personal needs. By building on recent advances in contextualized learning, these layers provide a meaningful learning context when people interact with people, digital and physical artefacts for their informal learning, thus making learning faster and more effective. Building on mobile learning research, we situate learning into physical work places and practices to support situated, faster and more meaningful learning. Learning Layers provide a shared conceptual foundation independent of the tools people use and the context they are in. Learning Layers are based on a common light-weight, distributed infrastructure that allows for fast and flexible deployment in highly distributed and dynamic settings. We apply these technologies in sectors that have been particularly hesitant to take up learning technologies, i.e. health care and building and construction. Involving two representative and large-scale regional SME clusters allows us to involve end users in co-design of the system and later scale up the approach to more than 1,000 learners within 4 years. By inviting a larger set of stakeholders to adapt and build on our solutions and through research in sustainable business training models, the project will generate significant impact by boosting the ability of regional innovation systems to adapt to change and thereby remain competitive, on the individual, organisational and regional level. We demonstrate the impact in the two chosen sectors, but widen the scope to other sectors and regions towards the end of the project.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.9.8 | Award Amount: 2.88M | Year: 2012

SENSATION aims at increasing the scale of systems that are self-supporting by balancing energy harvesting and consumption up to the level of complete products. In order to build such Energy Centric Systems, embedded system designers face the quest for optimal performance within acceptable reliability and tight energy bounds. Programming systems that reconfigure themselves in view of changing tasks, resources, errors and available energy is a demanding challenge.\nThe lack of effective design-time support for taking on this challenge obstructs the creativity and productivity of design teams. This is an impediment to European companies developing embedded components, devices, and platforms, and is a major obstacle to developing self-supporting systems.\n\nSENSATION will free the system design process by devising energy-centric modeling and optimization tools for the design of resource-optimal reliable systems. This depends on orchestrated, non-incremental progress in several research domains. The project combines Europes leading scientists in model-based quantitative evaluation and optimization, and in low-power reconfigurable systems.\n\nSENSATION provides automated analysis and synthesis tools for energy-centric systems. For the first time, tools for optimizing performance and reliability will be integrated with energy analysis. Based on efficient model-checking algorithms and massive design space exploration, this leads to a many-fold increase in system design productivity.\n\nTwo industrial partners, GomSpace and Recore Systems provide challenging case studies and serve as\nindustrial testbeds. The yardstick for the impact of SENSATION is a reduction in energy consumption by 50%\nand a reduction in time-to-market of at least 10%. An European institutes specializing in embedded systems,\nCISS, actively contributes to the development of the technology and its effective dissemination and industrial\nadoption.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.3.4 | Award Amount: 4.06M | Year: 2011

In recent years, massively parallel accelerator processors, primarily GPUs, have become widely available to end-users. Accelerators offer tremendous compute power at a low cost, and tasks such as media processing, simulation, medical imaging and eye-tracking can be accelerated to beat CPU performance by orders of magnitude. Performance is gained in energy efficiency and execution speed, allowing intensive media processing software to run in low-power consumer devices. Accelerators present a serious challenge for software developers. A system may contain one or more of the plethora of accelerators on the market, with many more products anticipated in the immediate future. Applications must exhibit portable correctness, operating correctly on any configuration of accelerators, and portable performance, exploiting processing power and energy efficiency offered by a wide range of devices. The aim of CARP is to design techniques and tools for correct and efficient accelerator programming: Novel & attractive methods for constructing system-independent accelerator programs Advanced code generation techniques to produce highly optimised system-specific code from system-independent programs\n Scalable static techniques for analysing system-independent and system-specific accelerator programs both qualitatively and quantitatively CARP will integrate these methods, providing a unified accelerator development flow. This will: Reduce the cost of accelerator programming and time-to-market quotas\n Increase energy efficiency of accelerated software, conserving battery life in mobile devices\n Increase confidence in the reliability of accelerated software. The CARP consortium is composed of leading European research experts and prominent tool providers. CARP will be validated at: Realeyes O, Estonia, developers of eye-tracking solutions\n Rightware Oy, Finland, developers of benchmarks for mobile devices\n ARM Ltd, UK, designers of the Mali GPU and associated tools.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-05-2014 | Award Amount: 3.49M | Year: 2015

The goal of POINT is to develop technology, innovations, and business value chains for commercially viable IP-over-ICN deployment, based on the hypothesis that many current IP-based applications can run better on an ICN-based network than on current IP networks. To achieve this, we will first define a set of Key Performance Indicators (KPIs) to specify what exactly better means. Then, we will specify a communication platform based on the ICN prototype developed in FP7 PURSUIT and develop a set of abstractions to enable current IP, TCP, HTTP and CoAP based applications to run on our platform, complemented by new resource coordination mechanisms to improve the performance of the network. We will implement our platform as an operational prototype and validate it against the KPIs in a testbed as well as run a real-world field trial in an operators production network with real customers. We will openly publish our design and all relevant data needed to deploy and improve our prototype, which in turn will be released as open source code. We will also undertake a wide range of dissemination activities to establish POINT as a key driver in the ICN community. The POINT platform will provide new business opportunities for systems vendors, operators and service providers, including SMEs and we will evaluate the commercial viability of our solution and develop migration scenarios for operators wishing to deploy ICN in production networks. The consortium has all the experience and competencies needed to cover the entire chain from an idea and research prototype to a working platform ready for production use. In addition to academic partners, POINT includes a technology company, a telecom vendor, an ISP, a content provider, and a cooperative which will enable POINT to have an impact on the industry.

Agency: European Commission | Branch: FP7 | Program: NOE | Phase: ICT-2009.4.2 | Award Amount: 7.59M | Year: 2010

The GaLA motivation stems from the acknowledgment of the potentiality of Serious Games (SGs) for education and training and the need to address the challenges of the main stakeholders of the SGs European landscape (users, researchers, developers/industry, educators). A foundational fault issue in this context is the fragmentation that affects the SG landscape.\nGALA aims to shape the scientific community and build a European Virtual Research Centre (VRC) aimed at gathering, integrating, harmonizing and coordinating research on SGs and disseminating knowledge, best practices and tools as a reference point at an international level. The other two key focuses of the project are (1) the support to deployment in the actual educational and training settings and (2) the fostering of innovation and knowledge transfer through research-business dialogue.\nThe NoE organizations aim to integrate their activities and resources in a long-term view structuring the activities along 3 major axes:\n\n\tResearch integration and harmonization.\no\tStrong integration among leading researchers, users and business;\no\tStrong concern on the current standards of education, in order to favour a real uptake and scaling of the educational games initiatives.\no\tAddress sustainability.\n\n\tJoint research activities.\no\tIdentify key issues and address them through multidisciplinary teams (putting always the users learners and teachers - and stakeholders in the centre of the focus) that will be iteratively explored;\no\tPromote Research and Development team forces organized in thematic areas - that will do focused research (e.g. joint PhD and MSc projects on hot SG research projects, joint project proposals) and continuously inform the project about the latest developments in technology and education;\n\n\n\tSpreading of excellence.\no\tDissemination of the NoE achievements as a flagship EU initiative in the TEL area\no\tStrong coordination with EU TEL activities, offering a specialized focus and expertise on SGs.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: NMP.2013.1.3-1 | Award Amount: 13.58M | Year: 2013

SUN (Sustainable Nanotechnologies) is the first project addressing the entire lifecycle of nanotechnologies to ensure holistic nanosafety evaluation and incorporate the results into tools and guidelines for sustainable manufacturing, easily accessible by industries, regulators and other stakeholders. The project will incorporate scientific findings from over 30 European projects, national and international research programmes and transatlantic co-operations to develop (i) methods and tools to predict nanomaterials exposure and effects on humans and ecosystems, (ii) implementable processes to reduce hazard and exposure to nanomaterials in different lifecycle stages, (iii) innovative technological solutions for risk management in industrial settings, and (iv) guidance on best practices for securing both nano-manufacturing processes and nanomaterials ultimate fate, including development of approaches for safe disposal and recycling. In summary, SUN stands for an integrated approach for the long-term sustainability of nanotechnologies through the development of safe processes for production, use and end-of-life processing of nanomaterials and products, as well as methods reducing both adverse effects and exposure to acceptable levels.

Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2014-ETN | Award Amount: 3.92M | Year: 2015

The proposed ITN entitled Modelling and computation of Shocks and Interfaces will focus on the training of young researchers in the general area of nonlinear hyperbolic and convection dominated PDEs with emphasis on innovative modelling and computational methods. The research program of the proposed ITN is centered on an important field (in terms of both history and scope), that is placed at the forefront of modern Computational and Applied Mathematics. The fact that hyperbolic convection dominated PDEs is probably one of the very few areas within Computational and Applied Mathematics, where traditionally modelling, Physics, Mechanics, analytical approaches, and advanced computational methods have contributed in synergy to several achievements to date, makes this field eminently suitable to train young researchers in. These researchers can become research leaders in a wide area as well as impacting on both industry and non-academic scientific institutions. The network will consist of some of Europes leading research groups on hyperbolic PDEs, and includes experts on Modelling, Analysis and Computation. A well defined training program is outlined in the proposal. The training program emphasises the European and international dimension of the effort. The training design is expected to produce effective results and foster the expertise on how to structure doctoral training at the European level and enhance the innovation capacity of the involved individuals. The innovative techniques developed will be applied to diverse concrete problems ranging from fluid dynamics and geophysical flows to materials science. In the pursuance of this goal, the research groups will be assisted by experts in these areas of application and non-academic partners, resulting in a significant enhancement of the impact of the research and training program.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC5-11a-2014 | Award Amount: 6.57M | Year: 2015

The overall aim of Real-Time-Mining is to develop a real-time framework to decrease environmental impact and increase resource efficiency in the European raw material extraction industry. The key concept of the proposed research promotes the change in paradigm from discontinuous intermittent process monitoring to a continuous process and quality management system in highly selective mining operations. Real-Time Mining will develop a real-time process-feedback control loop linking online data acquired during extraction at the mining face rapidly with an sequentially up-datable resource model associated with real-time optimization of long-term planning, short-term sequencing and production control decisions. The project will include research and demonstration activities integrating automated sensor based material characterization, online machine performance measurements, underground navigation and positioning, underground mining system simulation and optimization of planning decisions, state-of-the art updating techniques for resource/reserve models. The impact of the project is expected on the environment through a reduction in CO2-emissions, increased energy efficiency and production of zero waste by maximizing process efficiency and resource utilization. Currently economically marginal deposits or difficult to access deposits will be become industrial viable. This will result in a sustainable increase in the competitiveness of the European raw material extraction through a reduced dependency on raw materials from non-EU sources.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: LCE-02-2015 | Award Amount: 5.47M | Year: 2016

The overall objective of Residue2Heat is to enable the utilization of sustainable, ash rich biomass and residues in residential heating applications (20-200 kWth) to provide sustainable heat at a competitive price. In this concept, various 2nd generation agricultural, and forestry residue streams are converted into a liquid energy carrier near the biomass origin at an economic viable scale of 15-30 MWth using the fast pyrolysis process. Subsequently, the fast pyrolysis bio-oil (FPBO) is distributed to a large number of residential end-users. The FPBO should fulfill at least the draft CEN-specification for replacement of domestic heating oil and comply with REACH regulation. Additional quality control aspects for this application include the removal of extractives and solids from the FPBO. Ash is recovered from the fast pyrolysis process as a separate stream, and recycling and/or re-use will be evaluated in detail. Existing high efficient, condensing boilers are used as starting point in the project, as well as a proven, low emission blue-flame type burner. Within Residue2Heat technical development work is performed on the modification of such systems to enable FPBO as fuel. The emission control and energy efficiency of the heating systems are optimized by dedicated modeling of FPBO atomization and combustion kinetics, supported by single droplet combustion tests and spray characterization. This route benefits from the flexible nature of the fast pyrolysis process, allowing the use of various lignocellulosic biomass streams, but also by using modified residential heating systems for which manufacturing capabilities, market development and product distribution are already in place. Dedicated tasks are included to assess the environmental and social impacts, risks analysis and public acceptance. Additionally, business and market assessment activities are performed including specific issues on health and safety relevant to FPBO-fuelled residential boilers.

Agency: European Commission | Branch: H2020 | Program: IA | Phase: ICT-28-2015 | Award Amount: 10.29M | Year: 2016

Photonics is essential in todays life science technology. PIX4life will mature a state of the art silicon nitride (SiN) photonics pilot line for life science applications in the visible range and pave the way to make it accessible as an enabler for product development by a broad range of industrial customers. We aim at 1) establishing a validated CMOS compatible SiN technology platform in the visible range for complex densely integrated photonics integrated circuits (PICs), 2) developing a supply chain to integrate mature semiconductor laser sources and CMOS detector arrays with the SiN PICs on the basis of technologies that are scalable to high volume, 3) establishing appropriate design kits and tools, 4) demonstrating the performance of the pilot line for well-chosen life science applications in the domain of vital sensing, multispectral sources for super-resolution microscopy, cytometry and 3D tissue imaging, 5) setting up the logistics for multi-project-wafer (MPW) access to the pilot line. Integrated photonics has demonstrated that optical functions can be realized in a more compact, robust and cost-effective way by integrating functionalities on a single chip. At present industrialization is limited to telecom applications at infrared wavelengths. The field of life sciences is heavily dependent on bulky and expensive optical systems and would benefit enormously from low cost photonic implementations. However this field requires a visible light PIC-technology. Proof of concept demonstrations are abundant, but pilot line and manufacturing capacity is limited, inhibiting industrial take up. PIX4life will drive the future European RTD in visible photonic applications for life sciences by bridging technological research (via participation of 2 academic and 2 research institutes) towards industrial development (via participation of a foundry, two large companies and 9 fabless SMEs, either technology suppliers or life science end users).

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: ICT-04-2015 | Award Amount: 3.48M | Year: 2016

HiPEAC is a support action that aims to structure and strengthen the European academic and industrial communities in computing systems: (i) by increasing innovation awareness and by encouraging researchers to engage in innovation activities; (ii) by professionally disseminating program achievements beyond the traditional scientific venues; (iii) by producing a vision document including recommendations on how to improve the innovation potential of H2020 projects, and (iv) by growing the computing systems community beyond 2000 active members in Europe. The HiPEAC support action is meant to be the continuation of three successful FP7 networks of excellence with the same name (HiPEAC1-3). This support action will leverage the existing community, the expertise and the set of instruments that were developed since 2004 and work on the objectives of this support action: cross-sectorial platform-building, clustering of related research projects, structuring the European academic and industrial research communities, dissemination of programme achievements, impact analysis, constituency building and roadmapping for future research and innovation agendas. The overall approach of the HiPEAC support action is that it wants to bring together all actors and stakeholders in the computing systems community in Europe - especially EU-funded projects and SMEs - in one well managed structure where they can interact, disseminate/share information, transfer knowledge/technology, exchange human resources, think about their future challenges, experiment with ideas to strengthen the community, etc. The HiPEAC support action will support its members and projects with tasks that are too difficult/complex to carry out individually: vision building, professional communication, recruitment, event management at the European level. By offering such services a burden is taken away from the projects and members. They can then focus on the content, and the impact of their efforts is amplified.

Agency: European Commission | Branch: H2020 | Program: IA | Phase: LCE-05-2015 | Award Amount: 51.69M | Year: 2016

In order to unlock the full potential of Europes offshore resources, network infrastructure is urgently required, linking off-shore wind parks and on-shore grids in different countries. HVDC technology is envisaged but the deployment of meshed HVDC offshore grids is currently hindered by the high cost of converter technology, lack of experience with protection systems and fault clearance components and immature international regulations and financial instruments. PROMOTioN will overcome these barriers by development and demonstration of three key technologies, a regulatory and financial framework and an offshore grid deployment plan for 2020 and beyond. A first key technology is presented by Diode Rectifier offshore converter. This concept is ground breaking as it challenges the need for complex, bulky and expensive converters, reducing significantly investment and maintenance cost and increasing availability. A fully rated compact diode rectifier converter will be connected to an existing wind farm. The second key technology is an HVDC grid protection system which will be developed and demonstrated utilising multi-vendor methods within the full scale Multi-Terminal Test Environment. The multi-vendor approach will allow DC grid protection to become a plug-and-play solution. The third technology pathway will first time demonstrate performance of existing HVDC circuit breaker prototypes to provide confidence and demonstrate technology readiness of this crucial network component. The additional pathway will develop the international regulatory and financial framework, essential for funding, deployment and operation of meshed offshore HVDC grids. With 35 partners PROMOTioN is ambitious in its scope and advances crucial HVDC grid technologies from medium to high TRL. Consortium includes all major HVDC and wind turbine manufacturers, TSOs linked to the North Sea, offshore wind developers, leading academia and consulting companies.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: AAT-2007-2.2-02;AAT-2007-3.2-02 | Award Amount: 3.64M | Year: 2008

Airport ground processes still conceal a considerable potential for improvement of time efficiency. Recent studies from Eurocontrol Performance Review Commission prove that insufficient punctuality in air transport results mainly from variance in off-block times. This leads to poor predictability and sizeable inefficiencies throughout the whole air transport system. Aim of proposed project is to develop and assess solutions for airport process improvement in terms of time efficiency regarding both, passenger process and aircraft turnaround in an integrated approach. Therefore, representatives of nearly all directly or indirectly involved stakeholders (airports, airlines, aircraft manufacturers, technological suppliers, security service providers etc.) gathered to work conjointly on this project. Elaboration of potential solutions will comprise compilation of currently discussed solution approaches (e.g. CDM, Total Airport Management etc.) as well as development of new opportunities focussing on three main process chains: 1) passenger processes 2) baggage processes 3) aircraft turnaround processes Emphasis is placed on identifying those solutions achieving the most promising target contribution instead of going into details of a certain approach. Each solution first particular and in a later phase integrated solution scenarios deemed expedient, become assessed by dint of simulating characteristic traffic scenario into two generic airport reference models. These airport models are assigned to represent a hub airport (with a substantial part of connecting passengers) and a medium-sized airport (point-to-point and low-cost traffic), defined and generated in the context of this project. Suchlike models are lacking so far and could actually be used for other projects and assessments. Outcome will be a ranking list specifying most promising solutions as basis for future development, reference models and a systematic scheme for future airport assessments.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: AAT.2010.1.1-2. | Award Amount: 5.86M | Year: 2010

Todays design and certification procedures of aircrafts are mainly based on conservative static loading which leads to additional weight and, potentially, to a structurally unsafe aircraft. The overall objective of the DAEDALOS project is to develop methods and procedures to determine dynamical loads considering the effects of dynamic buckling, material damping and mechanical hysteresis during aircraft service. Use of advanced analysis and design principles from DAEDALOS will partly remove the uncertainty and the conservatism of todays design and certification procedures. DAEDALOS work will hence form the basis for improved common design practices by: 1. Determining accurate dynamic load spectra to be used for structural sizing. 2. Reducing the added weight of aircraft structural components due to conservative design in compliance with quasi-static loads by using more realistic equivalent dynamic loads. This goal will be achieved through improved introduction of the structure damping capacity and detailed analysis. 3. Increasing structural safety using more realistic loading scenarios. 4. Establishing new procedures for the definition of loads to be used during aircraft design and certification by authorities.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.9.10 | Award Amount: 2.74M | Year: 2013

CASSTING will develop a novel approach for analysing and designing collective adaptive systems in their totality, by setting up a game theoretic framework. Here components are viewed as players, their behaviour is captured by strategies, system runs are plays, and specifications are winning conditions.\n\nThe design of collective adaptive systems, as they occur, for example, in home automation, health care, and many scenarios of mobile communication, raises fundamental challenges: These systems are distributed, with heterogeneous\ncomponents interacting continuously among each other and with their environments, components may work collaboratively or as adversaries, they have to adapt over time, they are dynamic in the sense that components can come into existence or vanish, and their specification usually involves multi-dimensional quantitative objectives. Available methods (such as model-based verification and quantitative model-checking) only address selected aspects of collective adaptive systems.\n\nThe game theoretic approach of CASSTING is comprehensive and has already proved very successful in simpler scenarios such as automatic controller synthesis. The CASSTING research will lift this method to the level of collective adaptive systems and provide efficient algorithmic analysis methods as well as tools for the automatic synthesis. In particular, the simple scenario of zero-sum games is extended to cover a large variety of non-zero-sum games, and concepts of algorithmic game theory are generalised to infinite-duration games.\n\nThe CASSTING teams have made essential contributions in the area and are thus uniquely qualified for this project. The CASSTING research will strengthen the leading role that Europe already has in this field. The proof of concept will focus on the paradigmatic application areas of home automation and smart houses, based on case studies provided by the two internationally recognised industrial partners of the consortium.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: SST-2007-1.1-03 | Award Amount: 21.34M | Year: 2008

Main objective of Integrated gas powertrain (InGas) Collaborative Project is to deploy a custom designed engine integrated with specific aftertreatment systems applied to a light duty vehicle able to achieve a 10% higher fuel conversion efficiency than that of a corresponding 2006 diesel vehicle and complying with an emission level lower than Euro 6. Additional features are advanced storage systems and vehicle architectures, as well as multi-grade fuel tolerance and fuel flexibility. To achieve the InGas targets, three main combustion technologies will be compared: Sub-Project A1 CNG technologies for passenger cars will develop a natural gas car powered by a 1.4 liter displacement engine using the sequential multi-point port gas injection and following the stoichiometric approach; Sub-Project A2 Turbo DI CNG engine will develop a natural gas car powered by a 1.8 liter displacement engine using the direct gas in-cylinder injection and following a lean burn approach; Sub-Project A3 Boosted lean burn gas engine will develop a natural gas light-duty vehicle powered by a 1.9 liter displacement engine using port gas injection or low pressure direct gas injection and following the ultra-lean combustion approach. Three main enabling technologies will be compared and assessed Sub-Project B0 Fuels for advanced CNG engines will define / supply the gas mixture of the requested quality, conduct analysis and propose solutions in order to affect in a flexible way storage, combustion, aftertreatment and performance of the CNG vehicles; Sub-Project B1 Gas storage for passenger car CNG engine will develop advanced gas storage and filling systems including specific components and gas sensors; Sub-Project B2 Aftertreatment for passenger car CNG engine will develop an aftertreatment system for natural gas vehicles having special regards to CH4 conversion efficiency and NOx abatement under stoichiometric and lean combustion operations.

Agency: European Commission | Branch: H2020 | Program: SGA-RIA | Phase: FETFLAGSHIP | Award Amount: 89.00M | Year: 2016

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses ICT to integrate neuroscience data from around the world, to develop a unified multi-level understanding of the brain and diseases, and ultimately to emulate its computational capabilities. The goal is to catalyze a global collaborative effort. During the HBPs first Specific Grant Agreement (SGA1), the HBP Core Project will outline the basis for building and operating a tightly integrated Research Infrastructure, providing HBP researchers and the scientific Community with unique resources and capabilities. Partnering Projects will enable independent research groups to expand the capabilities of the HBP Platforms, in order to use them to address otherwise intractable problems in neuroscience, computing and medicine in the future. In addition, collaborations with other national, European and international initiatives will create synergies, maximizing returns on research investment. SGA1 covers the detailed steps that will be taken to move the HBP closer to achieving its ambitious Flagship Objectives.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: GV-02-2016 | Award Amount: 5.99M | Year: 2016

The decrease of CO2 & particulates emissions is a main challenge of the automotive sector. European OEMs and automotive manufacturers need new long term technologies, still to be implemented by 2030. Currently, hybrid powertrains are considered as the main trend to achieve clean and efficient vehicles. EAGLE project is to improve energy efficiency of road transport vehicles by developing an ultra-lean Spark Ignition gasoline engine, adapted to future electrified powertrains. This new concept using a conventional engine architecture will demonstrate more than 50% peak brake thermal efficiency while reducing particulate and NOx emissions. It will also reach real driving Euro 6 values with no conformity factor. This innovative approach will consequently support the achievement of long term fleet targets of 50 g/km CO2 by providing affordable hybrid solution. EAGLE will tackle several challenges focusing on: Reducing engine thermal losses through a smart coating approach to lower volumetric specific heat capacity under 1.5 MJ/m3K Reaching ultra-lean combustion (lambda > 2) with very low particulate (down to 10 nm) emission by innovative hydrogen boosting Developing breakthrough ignition system for ultra-lean combustion Investigating a close loop combustion control for extreme lean limit stabilization Addressing and investigating NOx emissions reduction technologies based on a tailor made NOx storage catalyst and using H2 as a reducing agent for SCR. A strong engine modeling approach will allow to predict thermal and combustion performances to support development and assess engine performances prior to single and multi-cylinder test bench application. An interdisciplinary consortium made of nine partners from four different countries (France, Germany, Italy, Spain) will share its cutting-edge know-how in new combustion process, sensing, control, engine manufacturing, ignition system, simulation & modeling, advanced coating, as well as after-treatment systems.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: GV-02-2016 | Award Amount: 12.06M | Year: 2016

PaREGEn addresses the short term scope of the GV-02 call via research into and the innovation of gasoline engines for light duty vehicles. Specifically, engines used in mid to premium passenger cars will be addressed. With the electrification smaller vehicles, focusing on larger cars is especially important: the need for clean, efficient & economic engines for inter-urban transport is more urgent and effective to resolve the challenges of air quality, decarbonisation & cost-effective mobility. Through using state of the art techniques, like optical engines, modelling & simulation tools (for new control strategies or understanding particle formation) and applying new engine componentry, the optimal trade-off between efficiency & emissions will be found. Of attention will be the control of particle numbers between 10 to 23nm. This learning will be used in two, manufacturer lead vehicle demonstrations. These demonstrators will use downsized engines not yet on the market. The two approaches will use different combustion, dilution, fuel injection, boosting and aftertreatment systems. Completion of the project will show the way forward to a 15% CO2 reduction along with real driving emissions limits. If adopted across all light vehicles these short term engine innovations will reduce the EU vehicle parc emissions by ~2MtCO2 in 2025, <10MtCO2 & ~10% PN>10nm in 2030. As well as improving EU competitiveness, a valuable contribution from PaREGEn will be new tools: to benefit engine design, development & control in general, long after project completion. PaREGEn has partners from EUCAR, CLEPA & EARPA; it is organized so learning from other projects in GV02 can be integrated. Experience from the PMP project and those proposed on particle measurement systems will be included via the partners & suppliers of PN-PEMS. PaREGEns partners give a global link to other nationally funded activities and, specifically, specialists in advisory roles will bring expertise from USA & Japan.

Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2016 | Award Amount: 3.08M | Year: 2017

For the selective and effective incorporation of oxygen into biological molecules (oxygenation reaction), several enzyme types have evolved in nature. They catalyse crucial reactions in various metabolic routes. The chemistry feasible with these biocatalysts is unrivalled when compared with conventional chemical methods. Therefore, these oxygenating enzymes are very promising tools in biotechnological approaches. However, when compared with other enzyme classes, such as hydrolases, oxygenases are still in their infancy considering their biotechnological potential. To fully exploit the catalytic power of oxygenases, several hurdles have to be taken for which a higher level of knowledge on these enzymes is needed while also technical aspects have to be solved. The European Training Network (ETN) OXYTRAIN is a joint academic/non-academic training initiative supporting the convergence of biochemistry, enzyme engineering and biotechnology. The consortiums mutual goal is developing a new generation of innovative and entrepreneurial early stage researchers (ESRs) to satisfy the need for knowledge and skills to produce and apply oxidative enzymes. This will be achieved by setting up a network and intersectoral programme in which multiple disciplines will be integrated and exploited. By bringing together 7 academic beneficiaries that are experts in the field of individual oxygenase groups, the network will provide perfect conditions for cross-fertilization of knowledge, while the 3 industrial beneficiaries and 5 partner organisations will add to the consortium by translating the generated knowledge into real industrial applications, such as textiles, pharmaceuticals and biorefineries.

Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2016 | Award Amount: 3.99M | Year: 2016

The world economy is dependent on fossil resources: oil, gas and coal. The fossil resources are finite and their consumption causes catastrophic environmental changes. Therefore we need to move towards sustainable economy using renewable resources for energy and chemicals production. Via metabolic engineering approach, novel microbial cells can be created that can convert biomass and waste into fuels and chemicals. Metabolic engineering however distinguishes itself from other engineering disciplines by low predictability of the design and long turnover times for the cell factory construction and screening. Therefore there is a need for scientists, who can address these challenges. European Training Network on Predictable and Accelerated Metabolic Engineering Networks (PAcMEN) will be established at 5 renowned European universities and 2 SMEs with participation of 5 industrial and 1 academic partner organizations. In this program 16 PhD students (of which 15 funded by EU contribution) will learn to conduct state-of-the-art research on metabolic engineering of microbial cell factories and learn to commercialize innovations. This will be achieved via collaborative research projects under supervision of top scientists from academia and industry, network training, secondments with network partners, training on innovation and entrepreneurship, and individual career coaching. Altogether, PAcMEN training programme will provide young scientists with the ideal combination of scientific, technological, industrial and management skills to prepare them for their role as breakthrough pioneers in the establishment of tomorrows biorefineries. The PAcMEN project will have an overall positive impact by strengthening the research networks in the area of metabolic engineering, establishing long-term collaborations between the universities and industry, and by creating a framework for future interdisciplinary training programs.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: SST-2007-3.1-01 | Award Amount: 13.04M | Year: 2012

CIVITAS-DYN@MO is an ambitious project with strategic importance to sustainable mobility planning in four dynamic European cities. Aachen (DE), Gdynia (PL), Koprivnica (HR) and Palma (ES) will jointly develop Mobility 2.0 systems and services, implement city and citizen-friendly, electric mobility solutions and vehicles, and engage in a dynamic citizen dialogue for mobility planning and service improvement. CIVITAS-DYN@MO is targeting dynamic citizens, and especially the digital natives in response to an emerging new mobility paradigm. A considerable part of the younger population in the DYN@MO university cities will be challenged to use web 2.0 apps to find appropriate means of travelling within the city and to communicate with PT operators. A sound basis for mobility planning is a citizen-centred Sustainable Urban Transport Plan. The two leading cities Aachen and Gdynia will advance their planning culture, while Koprivnica and Palma will develop ambitious sustainable urban transport plans all involving extensively citizens and stakeholders via web2.0 applications. Clean public transport remains the backbone of urban transport systems, and the cities have strong commitment to enhance the environmental performance and energy efficiency of their fleets. Alternative fuels, such as CNG and hybrid buses, and the increased use of electromobility in public transport and car sharing schemes will help to accelerate the introduction of clean vehicles in the European market. Venturing in new technology and mobility options as well as promoting new life styles will increase the peoples acceptance for mobility without a private car. The cities propose complementing packages with a high degree of transferability across Europe. Profound evaluation and research with strong dissemination and mutual learning through SUTP Competence Centres will strengthen the strategic impact of the project.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2013.3.4 | Award Amount: 3.43M | Year: 2013

The wellbeing of the citizens in Europe depends on the reliable and efficient functioning of large interconnected systems, such as electric power systems, air traffic control, railway systems, large industrial production plants, etc. Such large systems consist of many interacting components, e.g. generation plants, distribution systems, and large and small consumers. The subsystems are usually managed locally and independently, according to different policies and priorities. The dynamic interaction of the locally managed components gives rise to complex behaviour and can lead to largescale disruptions as e.g. black outs in the electric grid.\n\n\nLarge interconnected systems with autonomously acting subunits are called systems of systems. DYMASOS addresses systems of systems where the elements of the overall system are coupled by flows of physical quantities, e.g. electric power, steam or hot water, materials in a chemical plant, gas, potable water, etc. Within the project, new methods for the distributed management of large physically connected systems with local management and global coordination will be developed.\n\n\nThe approaches explored are:\n\n\tModelling and control of large systems analogously to the evolution of the behaviour of populations in biological systems;\n\tMarketlike mechanisms to coordinate independent systems with local optimisation functions;\n\tCoalition games where agents that control the subsystems dynamically group to pursue common goals.\n\n\nThe properties of the distributed management and control techniques for large systems of systems are investigated theoretically and validated in largescale simulations of case studies provided by industrial partners in the fields of electric grid management and industrial production management.\n\n\nFrom the experience gained in the case studies, conclusions will be drawn about the suitability of the proposed management and control mechanisms for certain classes of systems of systems.\n\n\nThe expected technical outcomes of the project are:\n \tInnovation in distributed management methods for complex interconnected systems\n \tProgress in methods for the rigorous analysis and validation of systems of systems;\n \tImprovements in the management of electric grids and of large production complexes;\n \tTools for the engineering of management systems for systems of systems;\n \tIdentification of technology gaps in advanced management and coordination methods.\n\n\nThe developed coordination methods will lead to improved system stability and lower resource consumption in industrial production, and in electricpower generation and distribution. This will result in a reduction of the CO2-emissions, higher competitiveness of the European industry and lower prices for the customers. Thus, DYMASOS will contribute to the goal of a greener and more competitive Europe.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2009.1.1 | Award Amount: 5.20M | Year: 2010

The current Internet architecture focuses on communicating entities, leaving aside the exchanged information. However, trends show that WHAT is exchanged is becoming more important than WHO are exchanging it. As a result, the Internet is effectively moving from interconnecting machines to interconnecting information, questioning the necessity of endpoint identifiers as a foundation of internetworking.\n\nThere have been efforts to introduce identifiers for information rather than endpoints on internetworking level, e.g., the FP7 PSIRP and the PARC CCN project, the former based on an information-centric publish/subscribe model and the latter based on a content-centric overlay. These efforts promise, among other things, more flexibility in adapting to new services, efficiency improvements on lower layers, and native multicast support.\n\nHowever, crucial questions remain, like (1) the role of caching, potentially leading to new concepts for congestion and error control, (2) the role of transport functions, (3) service-specific delivery solutions, and (4) support for disconnected operations. There are also open questions regarding the influence on lower layer operations, including resource allocation and reservation, resulting from the increased visibility of the exchanged information. Also, efficient re-allocation of optical resources and bundling of wireless resources need to be studied to gain insight into how such novel architecture can efficiently work with lower layers. Last, but not least, the socio-economic environment needs to be understood. The markets being created as well as the impact of socio-economics on design choices are as important as outlining the opportunities and threats for existing and new players to come. Demonstrating and validating practical solutions in experimental testbeds is needed for complementing such understanding.\n\nPURSUIT will pursue these endeavours in a collaborative project setting, building on recognized expertise in relevant areas.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2009.6.1 | Award Amount: 28.41M | Year: 2010

The interactIVe project addresses the development and evaluation of next-generation safety systems for Intelligent Vehicles, based on active intervention. Safety technologies have shown outstanding capabilities for supporting the driver in hazardous situations. Despite their effectiveness, currently available systems are typically implemented as independent functions. This results in multiple expensive sensors and unnecessary redundancy, limiting their scope to premium-class vehicles.\nThe project is based on the concept that by integrating applications together, vehicle components may be shared among the various safety systems. This is accomplished in interactIVe by discrete architectural layers that are common to all applications. These provide large amounts of knowledge about the driver, state of the vehicle, and the environment to all interested applications. The overall result is an optimal use of resources, lower implementation costs, and ultimately a much broader acceptance of the technology.\nAlthough application and sensor fusion is an active area of study, substantial amount of research is still required before its commercial feasibility. By building upon current state-of-the-art technologies, interactIVe will develop next-generation safety systems based on three pillar concepts, namely continuous driver support, collision avoidance, and collision mitigation.\nThe core activities of the project will address the design and development of the Intelligent Vehicle Systems, whose capabilities will be shown in demonstrator vehicles. The project will be conducted through a coordinated effort from leading automotive industries, suppliers, and research institutes.\nBy demonstrating these results, interactIVe will significantly enhance the feasibility and attractiveness of next-generation safety systems, strengthening the position of European industries in the area of Intelligent Vehicles and e-Safety.

Agency: European Commission | Branch: H2020 | Program: IA | Phase: GV-6-2015 | Award Amount: 9.95M | Year: 2016

Fuel economy is a key aspect to reduce operating costs and improve efficiency of freight traffic, thus increasing truck competitiveness. The main objective of the IMPERIUM project (IMplementation of Powertrain Control for Economic and Clean Real driving EmIssion and ConsUMption) is to achieve fuel consumption reduction by 20% (diesel and urea) whilst keeping the vehicle within the legal limits for pollutant emissions. The approach relies on three stages targeting the improvement of the control strategy: * Direct optimisation of the control of the main components (engine, exhaust after-treatment, transmission, waste heat recovery, e-drive) to maximize their performances. * Global powertrain energy manager to coordinate the different energy sources and optimize their use depending on the current driving situation. * Providing a more comprehensive understanding of the mission (eHorizon, mission-based learning) such that the different energy sources can be planned and optimized on a long term. The IMPERIUM consortium consist of major European actors and is able to provide a 100% European value chain for the development of future powertrain control strategies for trucks.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: FoF.NMP.2010-1 | Award Amount: 5.23M | Year: 2010

Self-sufficient intelligent plug-and-produce components with advanced sensing and actuating functionalities, e.g. based on smart materials. Able to adapt their range of properties, depending on the changing process conditions. Use vibration for energy harvesting to drive the intelligent system. Smart materials: compensation of static and / or thermally induced dislocations, vibration damping and decoupling of oscillations. High accuracy in production systems under different conditions and to overcome the traditional limitation of dynamics versus precision. Active participation of industrial partners, including SMEs, covering demonstration activities including pilot implementations in industrial settings.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: MG-3.6a-2015 | Award Amount: 9.61M | Year: 2016

ADAS&ME (Adaptive ADAS to support incapacitated drivers &Mitigate Effectively risks through tailor made HMI under automation) will develop adapted Advanced Driver Assistance Systems, that incorporate driver/rider state, situational/environmental context, and adaptive interaction to automatically transfer control between vehicle and driver/rider and thus ensure safer and more efficient road usage. To achieve this, a holistic approach will be taken which considers automated driving along with information on driver/rider state. The work is based around 7 provisionally identified Use Cases for cars, trucks, buses and motorcycles, aiming to cover a large proportion of driving on European roads. Experimental research will be carried out on algorithms for driver state monitoring as well as on HMI and automation transitions. It will develop robust detection/prediction algorithms for driver/rider state monitoring towards different driver states, such as fatigue, sleepiness, stress, inattention and impairing emotions, employing existing and novel sensing technologies, taking into account traffic and weather conditions via V2X and personalizing them to individual drivers physiology and driving behaviour. In addition, the core development includes multimodal and adaptive warning and intervention strategies based on current driver state and severity of scenarios. The final outcome is the successful fusion of the developed elements into an integrated driver/rider state monitoring system, able to both be utilized in and be supported by vehicle automation of Levels 1 to 4. The system will be validated with a wide pool of drivers/riders under simulated and real road conditions and under different driver/rider states; with the use of 2 cars (1 conventional, 1 electric), 1 truck, 2 PTWs and 1 bus demonstrators. This challenging task has been undertaken by a multidisciplinary Consortium of 30 Partners, including an OEM per vehicle type and 7 Tier 1 suppliers.

Agency: European Commission | Branch: H2020 | Program: IA | Phase: NMP-22-2015 | Award Amount: 8.05M | Year: 2016

BIO4SELF aims at fully biobased self-reinforced polymer composites (SRPC). To produce the SRPCs two polylactic acid (PLA) grades are required: a low melting temperature (Tm) one to form the matrix and an ultra high stiffness and high Tm one to form the reinforcing fibres. To reach unprecedented stiffness in the reinforcing PLA fibres, we will combine PLA with bio-LCP (liquid crystalline polymer) for nanofibril formation. Further, we will increase the temperature resistance of PLA and improve its durability. This way, BIO4SELF will exploit recent progress in PLA fibre technology. We will add inherent self-functionalization via photocatalytic fibres (self-cleaning properties), tailored microcapsules (self-healing properties) and deformation detecting fibres (self-sensing). Prototype composite parts for consumer goods, automotive and home appliances will be demonstrators to illustrate the much broader range of industrial applications, e.g. furniture, construction and sports goods. Our developments will enable to use biobased composites for high end applications, thus contributing to using sustainable and renewable raw materials. Being able to produce, process and sell these novel SRPCs and related composite intermediates will be a clear competitive advantage. First estimates predict a market of at least 35 kton/year, corresponding to ca. 165 M, within 5 years. Using the PLA SRPCs, BIO4SELF will demonstrate the successful use of biobased materials in home appliances such as washing machines, which partner ARCELIK intends to commercialise. BIO4SELF is a well balanced mix of end-users (large enterprises to maximise impact), technology providers (mainly R&D driven SMEs), R&D actors (RTDs and universities) and innovation support (specialised SMEs). It covers the required expertise, infrastructure, and industrial know-how to realise the innovation potential of the novel high performance biobased SRPCs, both during and beyond the project.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: FI.ICT-2011.1.8 | Award Amount: 9.13M | Year: 2011

The energy sector has entered a period of major change which will continue for many years to come. The increasing proportion of electricity from renewable sources means that the architecture of the energy grid will have to support the distributed, in addition to the centralised, generation of energy and to adapt to a highly volatile supply e.g. from wind and solar generators. From the consumption perspective, electric vehicles will demand new load management patterns in the grids. At the same time, private and commercial consumers are being encouraged to reduce their energy use and electronics manufacturers are striving to reduce the energy use of their products. The energy supply will need to evolve into a dynamic system to provide the smart energy infrastructure needed to support society in 2020 and beyond.\n\nFuture Internet technologies will play a critical role in the development of Smart Energy infrastructures, enabling new functionality while reducing costs. In the FINSENY project, key actors from the ICT and energy sectors will team-up to identify the ICT requirements of Smart Energy Systems. This will lead to the definition of new solutions and standards, verified in a large scale pan-European Smart Energy trial. Project results will contribute to the emergence of a sustainable Smart Energy infrastructure, based on new products and services, to the benefit of all European citizens and the environment.\n\nAs part of the FI-PPP programme, FINSENY will intensively analyse energy-specific requirements together with the other FI-PPP projects, develop solutions to address these requirements, and prepare for a Smart Energy trial in phase two of the programme. The growing FINSENY Smart Grid Stakeholder Group will provide broad visibility of the on-going project work in the energy community, enhancing the acceptability of the project results and facilitating the development of the smart energy market.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: TPT.2011.1-2. | Award Amount: 1.22M | Year: 2011

The aim of GOAL is to provide an action plan for innovative solutions to fulfil the transport needs of an ageing society. This action plan will be developed by state-of-the-art reviews, identification of possible and relevant societal developments and alternatives to transport. We identify relevant research gaps and product developments through contacts in the USA and Japan. The focus of GOAL is on land-based transport. Current predictions of EUROSTAT show that The share of people aged 65 years or over in the total population is projected to increase from 17.1% to 30.0% and the number is projected to rise from 84.6 million in 2008 to 151.5 million in 2060. Similarly, the number of people aged 80 years or over is projected to almost triple from 21.8 million in 2008 to 61.4 million in 2060. In order to keep them actively involved in society and maintain independence, it is vital that older people, now and in the future, are able to travel and have access to transport. In GOAL we describe the physical and mental characteristics of older people and use these to develop profiles which will represent the range of characteristics to be formed in the population now and in the future. These profiles will be used to explore in a structured way the needs while driving, using public transport, walking and cycling and the relevant information needed before and during travel. The profiles will also be used to address additional issues of older people and other developments which may impact on travel decisions in the future. There is considerable expertise in the consortium related to all aspects of the project. However, to validate our work and to ensure that it will have the widest acceptance, we will be running a series of workshops to enable the widest constituency of stakeholder bodies and experts to interact with the study team. The research and development needs will be identified and used to develop an action plan to achieve the goal of growing older and staying mobile.

Agency: European Commission | Branch: FP7 | Program: NOE | Phase: ICT-2009.1.1 | Award Amount: 4.15M | Year: 2010

Wireless communications, perpetually a source of innovation, is entering new and uncharted territory. In order to enhance system performance and cater for the services and applications of the future, there is the need for cooperative and cognitive communications paradigms that support advanced coexistence technologies for radio optimization. In short, wireless communications is moving towards a disruptive phase, where the speed and capability of interdisciplinary knowledge integration, for systems cooperation and coexistence, becomes a requirement for survival. This needs new thinking, and the development of architectures and facilitators for novel flexible radio technologies. To account for this paradigm shift and position Europe to benefit most from it, experts in areas of cooperation and coexistence, comprising but not limited to realms such as cognitive radio, cognitive networking and flexible networking, must integrate and harmonize their agendas. Through this approach, to paraphrase a common adage, the whole will become stronger than the sum of the parts. Moreover, there is the need to produce a next generation of European researchers, with the right skills-sets to solve the challenges of optimisation for cooperative and coexisting wireless systems. The ACROPOLIS NoE is specifically designed to meet these challenges; it has a strong, interdisciplinary, joint-research agenda, fostering rapid innovation that is of the highest quality and is able to bridge the gaps in European research. Its structure allows it to react rapidly to changes in the research landscape, where integration of research activities to achieve critical mass, and spreading of excellence throughout industry, other research organisations and elsewhere, are at the very heart of its formulation and ideals. To summarise, ACROPOLIS fosters relevant European excellence in research and education, and through the amalgamation of this strives to achieve new heights that would otherwise be impossible.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SFS-05-2015 | Award Amount: 5.14M | Year: 2016

The main objective of GoodBerry is to provide the necessary knowledge and procedures to facilitate the development of highly productive and top quality berry fruits, even under multiple suboptimal growth conditions, at a competitive cost. The project is based on an integrative multi-actor approach, from cultivation techniques to molecular studies, aiming the development and validation of a range of tools to improve competitiveness of European berry production, and eventually the attraction and confidence of consumers. The selection of the model species can be considered as strategic since strawberry is the most important berry crop in Europe and the production of raspberry and blackcurrant are increasing strongly in recent years. The project will apply the most recent technical advances in: a) The identification of berry germplasm exhibiting advantageous balance of production vs nutritional quality throughout the EU, b) The search of innovative production systems to maintain high yield in a range of European-wide environments, c) The development of standardized and reliable analytical tools to evaluate berry production and fruit quality. As result, it is expected: a) the implementation of modern breeding strategies to accelerate the release of new berry cultivars; b) The adoption by EU-growers of high quality production systems to improve fruit quality. The proposal establishes as obligatory to disseminate and communicate the results to the scientific community, industry, the broad public and interested stakeholders user. The final impact will be to consolidate the emerging needs of high-quality berries, and to boost consumer and market confidence supported by an improved competitiveness of producers. It is a multidisciplinary, collaborative project based on complementary expertise and skills of internationally recognized berry research institutions, and highly involved key berry SMEs that will combine their effort to secure the robustness of the results.

Agency: European Commission | Branch: FP7 | Program: CPCSA | Phase: ICT-2013.9.9 | Award Amount: 72.73M | Year: 2013

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the FET Flagship Programme, is to translate this vision into reality, using ICT as a catalyst for a global collaborative effort to understand the human brain and its diseases and ultimately to emulate its computational capabilities. The Human Brain Project will last ten years and will consist of a ramp-up phase (from month 1 to month 36) and subsequent operational phases.\nThis Grant Agreement covers the ramp-up phase. During this phase the strategic goals of the project will be to design, develop and deploy the first versions of six ICT platforms dedicated to Neuroinformatics, Brain Simulation, High Performance Computing, Medical Informatics, Neuromorphic Computing and Neurorobotics, and create a user community of research groups from within and outside the HBP, set up a European Institute for Theoretical Neuroscience, complete a set of pilot projects providing a first demonstration of the scientific value of the platforms and the Institute, develop the scientific and technological capabilities required by future versions of the platforms, implement a policy of Responsible Innovation, and a programme of transdisciplinary education, and develop a framework for collaboration that links the partners under strong scientific leadership and professional project management, providing a coherent European approach and ensuring effective alignment of regional, national and European research and programmes. The project work plan is organized in the form of thirteen subprojects, each dedicated to a specific area of activity.\nA significant part of the budget will be used for competitive calls to complement the collective skills of the Consortium with additional expertise.

Agency: European Commission | Branch: FP7 | Program: MC-ITN | Phase: FP7-PEOPLE-ITN-2008 | Award Amount: 5.02M | Year: 2009

There is widespread concern about how production and use of chemicals affect the environment. Yet food production and benefits of chemical products are vital for the functioning of European societies. In order to ensure sustainable use, EU regulations require extensive risk assessment before a chemical is approved for use. Current risk assessments focus on risk at the level of individual organisms, but according to EU directives the protection goal aims at achieving sustainable populations. Population-level effects depend not only on exposure and toxicity, but also on important ecological factors that are impossible to fully address empirically. Mechanistic effect models (MEMs) enable the integration of these factors, thus increasing the ecological relevance of risk assessments as well as providing vital understanding of how chemicals interact with ecosystems. Such understanding is crucial for improving risk mitigation strategies and ecosystem management. So far, however, regulators and industry have lacked understanding of the potential benefits that MEMs can deliver, and academics have been inconsistent in the approaches applied. This has led to scepticism about models, preventing a wider use of MEMs in risk assessment. Examples clearly demonstrating the power of MEMs for risk assessment are urgently needed, and industry, academia and regulatory authorities across Europe need scientists that are trained in both MEMs and regulatory risk assessment. CREAM will develop and experimentally validate a suite of MEMs for organisms relevant for chemical risk assessments. The consortium includes the main sectors involved (industry, academia, regulators) and will formulate Good Modelling Practice that will be followed in all individual projects, thus leading to consistency and transparency. CREAM will provide world class training for the next generation of ecological modellers, emphasizing transparency and rigorous model evaluation as core elements of the modelling process.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: NMP-2009-3.2-1 | Award Amount: 15.99M | Year: 2010

The SYNFLOW vision is the paradigm shift from batch-wise large volume processes in pharmaceuticals, fine chemicals and intermediates production comprising many separate unit operations towards highly integrated but yet flexible catalytic continuous flow processing. For this purpose, SYNFLOW develops a unique integrative approach combining molecular understanding of synthesis and catalysis with engineering science in process design and plant concepts, aiming at an efficiency breakthrough in process development and operation. The SYNFLOW mission is to overcome the traditional way of linear process development providing individual solutions for specific products, and to demonstrate the technological, economic and ecological superiority of truly designing processes by application of advanced chemical and engineering knowledge. The SYNFLOW concept is based on the definition of generic challenges with industrial relevance, represented by Case Studies provided by the industrial consortium members. Catalyst development, studies of the underlying chemical target transformations (synthetic methodology), tailored reaction engineering, conceptual process design and process evaluation interact closely in order to substantiate the SYNFLOW vision. Its success will be demonstrated on a relevant production scale as a reference for the entire European Chemical Industry. The SYNFLOW consortium brings together major industrial producers from the Pharmaceuticals, Fine Chemicals and Intermediates sectors, providers of process technology and technical catalyst supply. A number of high-ranked academic partners ensures the availability of comprehensive expertise for the suggested Case Studies. Dissemination of the results is guaranteed by the participation of DECHEMA and Britest. SYNFLOW presents a holistic approach to central challenges of the European Chemical Industries and therefore a highly promising candidate to fulfill the crucial issues of the NMP-2009-3.2-1 call.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.1.1 | Award Amount: 26.75M | Year: 2012

In 2020, mobile and wireless traffic volume is expected to increase thousand-fold over 2010 figures. Moreover, an increase in the number of wirelessly-connected devices to counts in the tens of billions will have a profound impact on society. Massive machine communication, forming the basis for the Internet of Things, will make our everyday life more efficient, comfortable and safer, through a wide range of applications including traffic safety and medical services. The variety of applications and traffic types originating from or reaching mobile, WLAN, and sensor networks, will be significantly larger than today, and will result in more diverse requirements on services, devices and networks.\n\nMETIS is set up by leading global players to prepare the migration from todays mobile systems, focused on human communications, towards tomorrows multi-purpose global communication infrastructure, serving humans and things.\n\nThe main objective of METIS is to lay the foundation for, and to generate a European consensus on this future global mobile and wireless communications system. METIS will provide valuable and timely contributions to pre-standardisation and regulation processes, and ensure European leadership in mobile and wireless communications.\n\nMETIS will provide fundamentally new solutions which fit the needs beyond 2020. Research will be conducted on network topologies, radio links, multi-node, and spectrum usage techniques. Horizontal topics will be used to integrate the research results into a system concept that provides the necessary flexibility, versatility and scalability at a low cost. The METIS concept will be evaluated, and a roadmap will be generated.\n\nMETIS is a strong European consortium, completed by selected non-European partners to ensure global harmonisation. The consortium gathers major telecommunication stakeholders; vendors, operators and academic researchers, together with a new partner from the automotive industry to provide new insights

Agency: European Commission | Branch: FP7 | Program: MC-ITN | Phase: FP7-PEOPLE-2013-ITN | Award Amount: 3.94M | Year: 2013

The goal of a sustainable society requires the efficient use of renewable or sustainable materials and demands the development of selective new methodologies for the preparation of desirable products. In this context we require: (i) a change from traditional stoichiometric, high energy methods that produce huge amounts of chemical waste to mild and clean catalytic processes and (ii) a major step change in chemicals production with fossil fuels being replaced by renewable resources as chemical starter units. In this proposal we have identified a series of collaborative projects that would benefit from the mutual exchange of scientific expertise between several European academic and industrial partners. This collaboration will provide new links within the EU to be established in order to train a new generation of scientists to deliver research excellence in the challenging change from fossil to renewable resources. The challenge to change our societies reliance for chemical production from fossil-fuel based to all-renewable resources is a challenge of enormous scale.This change must be broken down into smaller, manageable components capable of demonstrating the effectiveness of this strategy in order to showcase the transition necessary. In this proposal we will establish links with world leading experts to develop leading examples of this approach and have identified several areas where we believe collaboration can impact. Using the complementary multidisciplinary expertise from the network partners we will: Develop optimal catalysts for ether cleavage in real life samples of lignin for maximising the potential of lignocellulose as a source of fuels and fine chemicals. The most successful catalyst systems developed will be immobilized using advanced fluids and these systems will be fully explored and optimised through collaboration within this ITN consortium.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: HEALTH.2013.1.3-1 | Award Amount: 15.99M | Year: 2013

HeCaToS aims at developing integrative in silico tools for predicting human liver and heart toxicity. The objective is to develop an integrated modeling framework, by combining advances in computational chemistry and systems toxicology, for modelling toxic perturbations in liver and heart across multiple scales. This framework will include vertical integrations of representations from drug(metabolite)-target interactions, through macromolecules/proteins, to (sub-)cellular functionalities and organ physiologies, and even the human whole-body level. In view of the importance of mitochondrial deregulations and of immunological dysfunctions associated with hepatic and cardiac drug-induced injuries, focus will be on these particular Adverse Outcome Pathways. Models will be populated with data from innovative in vitro 3D liver and heart assays challenged with prototypical hepato- or cardiotoxicants; data will be generated by advanced molecular and functional analytical techniques retrieving information on key (sub-)cellular toxic evens. For validating perturbed AOPs in vitro in appropriate human investigations, case studies on patients with liver injuries or cardiomyopathies due to adverse drug effects, will be developed, and biopsies will be subjected to similar analyses. Existing ChEMBL and diXa data infrastructures will be advanced for data gathering, storing and integrated statistical analysis. Model performance in toxicity prediction will be assessed by comparing in silico predictions with experimental results across a multitude of read-out parameters, which in turn will suggest additional experiments for further validating predictions. HeCaToS, organized as a private-public partnership, will generate major socioeconomic impact because it will develop better chemical safety tests leading to safer drugs, but also industrial chemicals, and cosmetics, thereby improving patient and consumer health, and sustaining EUs industrial competitiveness.

Agency: European Commission | Branch: FP7 | Program: BSG-SME-AG | Phase: SME-2011-2 | Award Amount: 2.80M | Year: 2011

STEPMAN project aims to produce an instrument for European Machine Tool Manufacturing SMEs, which helps to increase their competitiveness: - By providing efficient quality control software, increasing the quality of their products. The reproduction of a product will be much more accurate using a STEP-NC compliant integrated file format throughout the whole production chain. The differences in translating CAD/CAM information to post-processors will be eliminated, and the changes in CAD/CAM models will be recorded and stored in a reusable form. - By savings on production time (faster response delivery), decreasing their manufacturing costs. The very usua repeated production of a given product in this sector will take an estimated 20% less time. - By developing a software tool, which makes possible joining design and production made by different companies using different CAD/CAM software (e.g. due to different software suppliers). Difference in data formats is one of the most important limiting factors in flexibility and cooperation of machine tool manufacturing SMEs.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.3.1 | Award Amount: 4.40M | Year: 2012

Charge storage has been the main physical mechanism supporting all solid state mass storage memories until now, both DRAM and FLASH. However none of the two main memory types appear to fully satisfy system requirements, DRAM because of its volatility and large power dissipation, and FLASH because of its slow programming speed and large block organization. PCM technology is a promising candidate to target the universal memory matching most of the properties of FLASH and DRAM. However, to realize the full potential of PCM two crucial memory characteristics have to be improved: programming current and switching speed.The new memory concept investigated in the project is based on engineered Chalcogenide SuperLattices (CSL) that should allow realizing the memory switching with a modification in the bonding nature instead of the energy expensive melting process, bringing about a significant reduction of both transition times and programming currents. Despite the convincing experimental evidence the physical mechanism is not yet understood.The project aims at exploiting the potential of CSL-PCM memory cells, starting from an atomistic understanding of switching in CSL materials through experiments and physical model development, leading to new insights for CSL engineering. Optimization of the CSL device will be achieved through the development of a test vehicle allowing the benchmark among different stacks, based on universal memory electrical performance targets. A large array, realized at 2X technology node, will be fabricated and integration issues will be addressed. Scalability to the 1X node will be also evaluated to demonstrate the capability to become a real universal memory also for the next generations of memory chips.At the end of the project a first universal memory chip at the state of the art technology node will be available with an expected direct impact on the solid state memory market.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.3.7 | Award Amount: 2.77M | Year: 2008

Manufacturing systems, power networks, transportation systems, road traffic networks, process plants, and other large-scale networked systems are often composed of multiple subsystems, with many embedded sensors and actuators, and characterised by complex dynamics and mutual influences such that local control decisions have long-range effects throughout the system. This results in a huge number of problems that must be tackled for the design of an overall control system in order to achieve a safe, efficient, and robust operation. Otherwise, serious disasters and malfunctions could occur (such as the breakdown of the power grid in North America and in Italy in 2003).To deal with these problems and to cope with the complexity of the control task, we propose to use a hierarchical control set-up in which the control tasks are distributed over time and space. In such a set-up, systems of supervisory and strategic functionality reside at higher levels, while at lower levels the single units, or local agents, must guarantee specific operational objectives. At any level, the local agents must negotiate their outcomes and requirements with lower and higher levels. We will develop methods for designing controllers for complex large-scale systems based on such a hierarchical control framework. In particular, we propose to use Model Predictive Control (MPC), which has already proven its usefulness for control of small-scale systems, but which cannot yet be applied to large-scale systems due to computational, coordination, and communication problems. We will solve these issues and develop new MPC methods for large-scale networked systems, both under normal operation conditions, and in the presence of uncertainty and disturbances.We will perform both fundamental research and more application-oriented research in which the methods developed in the project are applied to case studies and benchmarks provided by the partners from industry.

Agency: European Commission | Branch: FP7 | Program: CP-CSA-Infra | Phase: INFRA-2010-1.1.29 | Award Amount: 8.13M | Year: 2011

VISIONAIR is a project of creation of a European infrastructure that should be a unique, visible and attractive entry towards high level visualisation facilities. These facilities must be open to the access of a wide set of research communities. By integrating existing facilities, it will create a world-class research infrastructure enabling to conduct frontier research. This integration will provide a significant attractiveness and visibility of the European Research Area. Current scientific challenges concern climate evolution, environmental risks, health, energy, etc. and require the management of more and more complex information. The development of information technologies, the increasing complexity of the information to be handled and analysed, along with the increasing capacities in scientific and engineering simulations, call for the development of increasingly powerful visualisation tools and methods. The Europe Research Area must be able to compete with other big Research Areas when addressing the previously defined challenges. By integrating visualisation facilities with the VISIONAIR project, ERA will be able to answer integrated challenges out of the scope of usually disseminated research teams. Both, physical access and virtual services, will be provided by the infrastructure. A full access to visualisation dedicated software will be organised, while physical access on high level platforms, will be partially (about 20% of global usage) open for other scientists for free on behalf of excellence of submitted projects. The partners of this project propose to build a common infrastructure that would grant access to high level visualisation facilities and resources to researchers. Indeed, researchers from Europe and from around the world will be welcome to carry out research projects using the visualisation facilities provided by the infrastructure. Visibility and attractiveness of ERA will be increased by the invitation of external projects.

Agency: European Commission | Branch: FP7 | Program: NOE | Phase: ICT-2007.3.1 | Award Amount: 5.46M | Year: 2008

NANOSIL Network of Excellence aims to integrate at the European level the excellent European research laboratories and capabilities in order to strengthen scientific and technological excellence in the field of nanoelectronic materials and devices for terascale integrated circuits (ICs) and disseminate the results in a wide scientific and industrial community.NANOSIL will explore and assess the science and technological aspects of nanodevices and operational regimes relevant to n\4 technology node and beyond. It will provide a forward-look for the industry, enabling informed decisions to be taken on technology development in order to speed up technological innovation. It will encompass flagship projects on nanoscale CMOS and post-CMOS. The activities will thus be centred on the More Moore and Beyond-CMOS domains but natural links will also been established with the other ENIAC areas. Within the Network there are all the critical facilities and expertise to occupy and transcend this space. We will propose innovative concepts, technologies and device architectures- with fabrication down to the finest features, and utilising a wide spectrum of advanced deposition and processing capabilities, extensive characterisation and world leading device modelling. This work will be carried out through a network of joint processing, characterisation and modelling platforms. The consortium will work closely with and take steering from European industry. It will feed back data and know-how on materials and devices that deliver the required performance. This critical interaction will strengthen European integration in nanoelectronics, help in decision-making by industry and ensure that Europe remains at the forefront of nanoelectronics for the next 2 3 decades.

Agency: European Commission | Branch: FP7 | Program: CP-CSA-Infra | Phase: INFRA-2007-2.2-01 | Award Amount: 15.61M | Year: 2008

The Large Hadron Collider upgrade (SLHC) is the project with highest priority in The European strategy for particle physics document, unanimously approved by the CERN Council in July 2006. The SLHC, with expected 1 B budget, includes the upgrade of specific elements of the LHC accelerator, major upgrades in the accelerator injector complex, as well as upgrades to the two high-luminosity experiments ATLAS and CMS. It will result in a tenfold increase of the LHC luminosity. Thus the SLHC will remain the most powerful particle accelerator in the world in the next two decades. The Preparatory Phase project of the LHC-upgrade (SLHC-PP), co-funded by the EC, comprises Coordinating, Support and Technical activities. The Coordinating activities within SLHC-PP play a central role for the organisation of the new accelerator- and detector-upgrade collaborations, putting in place project structures and collaboration management tools, ultimately aiming for agreements on work-sharing and funding for the implementation phase. Support activities address upfront priority safety issues in the radiation protection domain. The Technical developments address the construction of prototypes of Nb-Ti high-field magnets with large aperture, the study of a new H- ion source, field stabilization in superconducting accelerating structures, and novel tracking detector power distribution. The SLHC-PP project runs in parallel with an extensive SLHC-oriented R&D program, funded by CERN together with important contributions from many CERN member and non-member states. In order to prepare for the SLHC project implementation as a whole, the coordination tasks within SLHC-PP include the coordination of these developments carried out outside SLHC-PP. The main aim of SLHC-PP is to prepare the SLHC project for a decision on the approval of its implementation by 2011. Beside the justification of SLHC by the physics results and operational experience from the first years of LHC running, the necessary ingredients for the approval will include: the maturity of new technologies required for SLHC, solutions for critical safety issues, and the formation of collaborations for the implementation, including the definition of work sharing and financial commitments. The SLHC-PP project is fully set up to address these issues and to prepare for the approval by the CERN council and by all other funding agencies involved.

Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: SSH-2007-8.0-02 | Award Amount: 495.23K | Year: 2008

This Action will promote research collaboration and engagement between research and policy in relation to Information Technology standardisation in China & Europe. The Peoples Republic of China has recently begun to be remarkably active in many areas of ICT interoperability standards. This raises important issues for China about standardisation processes and technology promotion policy. Their outcome will have important consequences for the European economy and global ICT market. They are flagged as of particular interest to the FP7 Information Society Technologies programme. This project brings together the leading European and Chinese centres for research into ICT Interoperability Standards for a comparative examination of ICT standardisation processes and associated policies between EU and China. It will develop a knowledge network of top researchers in the field in Europe, China and beyond. It will examine the new ICT standardisation activity emerging in China, apparently linked to its goals to promote indigenous technology, and compare these emerging standardisation processes with the more established approaches that have evolved at a European level. Three strategic studies will address a selected sample of areas flagged by IST as bearing critically on European technology and industrial strategy. They will examine the standardisation approach adopted; the strategies of public policy, technical and industrial players; the likely implementation/uptake of standards and their consequences for innovation and markets. In particular: will the outcomes be open standards and alignment between regional economies or competitive standards processes leading to so-called standards wars or the fragmentation of global markets. Attention will be paid to social learning by standardisation bodies, industry and policy actors. Findings will be discussed with Chinese & European standards bodies and policy communities, who will assist in pulling out the policy implications.

Agency: European Commission | Branch: FP7 | Program: CSA | Phase: ICT-2009.4.2 | Award Amount: 2.53M | Year: 2010

This proposal focuses on topic f) of call 5: exploratory/Roadmapping activities for fundamentally new forms of learning to support take-up of those new forms, via Awareness building and knowledge management on the results of EU RTD projects in TEL and socio-economic evaluations in education and for SMEs. We gather information on the current, desired and emerging position of TEL, and on awareness and appropriation (by educators and SMEs) of RTD results in TEL. We codify that information using state of the art knowledge management tools/ methods, at three levels of scale: 1) macro (political, economic, social, technological, legal, environmental), 2) meso (organisation of education and training systems and institutions), and 3) micro (enacted paradigms of learning and teaching). Cutting across these levels of scale is the categorisation of changes as exogenous or endogenous relative to forms of learning and to the TEL community. This provides direct input to TEL-relevant decisions at all three levels, including economic, political, and research discussions. With a 10-year horizon, we co-develop a portfolio of stakeholder-specific roadmaps and influence maps, to gain insights into fundamentally new forms of Learning, Education and Training activities (LET) and into what makes for effective transfer and scalability. Our collaborative development approach leads to a Multi-perspective Dynamic Roadmap to track, anticipate and manage knowledge about new forms of LET and their impact on TEL. This extends established TEL Roadmapping methods in novel, powerful and cost-effective ways, with high potential for sustainability and for targeting each stakeholders goals. Outcomes include well-grounded recommendations on TEL and LET innovations, plus a platform and a sustainable dynamic process that will foster collaboration and consensus-building across specialized communities and stakeholder groups.

Agency: European Commission | Branch: FP7 | Program: NOE | Phase: ICT-2007.3.3 | Award Amount: 5.77M | Year: 2008

The ArtistDesign NoE is the visible result of the ongoing integration of a community, that emerged through the Artist FP5 Accompanying Measure and that was organised through the Artist2 FP6 NoE.\nThe central objective for ArtistDesign is to build on existing structures and links forged in Artist2, to become a virtual Center of Excellence in Embedded Systems Design. This will be mainly achieved through tight integration between the central players of the European research community. Also, the consortium is smaller, and integrates several new partners. These teams have already established a long-term vision for embedded systems in Europe, which advances the emergence of Embedded Systems as a mature discipline.\nArtistDesign will become the main focal point for dissemination in Embedded Systems Design, leveraging on well-established infrastructure and links, such as a web portal and newsletter. It will extend its dissemination activities, including Education and Training, Industrial Applications, as well as International Collaboration. ArtistDesign will establish durable relationships with industry and SMEs in the area, especially through ARTEMISIA/ARTEMIS.\nArtistDesign will build on existing international visibility and recognition, to play a leading role in structuring the area.\nThe research effort aims to integrate topics, teams, and competencies, grouped into 4 Thematic Clusters: Modelling and Validation, Software Synthesis, Code Generation, and Timing Analysis, Operating Systems and Networks, Platforms and MPSoC. Transversal Integration covering both industrial applications and design issues aims for integration between clusters.\nArtistDesign has defined a four-year workprogramme, with a strong commitment to integration and sustainability. To achieve the aims, the estimated support from the EC is approximately 4.5 MEuros. This support is a very small proportion of the overall investment by the core partners.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: KBBE-2007-3-2-03 | Award Amount: 7.44M | Year: 2008

Enzymes are extremely powerful natural catalysts able to perform almost any type of chemical reaction while being mild by nature and highly specific. In fact, the delicate functioning of enzymes forms the basis of every living creature. The catalytic potential of enzymes is more and more appreciated by the industry as many industrial processes rely on these sophisticated catalysts. However, the number of reactions catalyzed by enzymes is restricted as enzymes only have evolved to catalyze reactions that are physiologically relevant. Furthermore, enzymes have adapted to the direct (cellular) environment in which they have to function (e.g. operative at ambient temperature, resilient towards proteolysis, catalytic turnover rate should fit with metabolic enzyme partners). This excludes the existence of enzymes that do not fit within boundaries set by nature. It is a great challenge to go beyond these natural boundaries and develop methodologies to design unnatural tailor-made enzymes. Ideally it should become possible to (re)design enzymes to convert pre-defined substrates. Such designer enzymes could theoretically exhibit unsurpassed catalytic properties and, obviously, will be of significant interest for industrial biotechnology. The OXYGREEN project aims at the design and construction of novel oxygenating enzymes (designer oxygenases) for the production of compounds that can be used in medicine, food and agriculture and the development of novel powerful and generic enzyme redesign tools for this purpose. The enzymes and whole-cell biocatalysts that will be developed should catalyze the specific incorporation of oxygen to afford synthesis of bioactive compounds in a selective and clean way, with minimal side products and with no use of toxic materials. For this, generic platform technologies (novel high-throughput methodology and methods for engineering dedicated host cells) will be developed that allow effective structure-inspired directed evolution of enzyme.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: GV-2-2014 | Award Amount: 6.39M | Year: 2015

Optimised energy management and use (OPTEMUS) represents an opportunity for overcoming one of the biggest barriers towards large scale adoption of electric and plug-in hybrid cars: range limitation due to limited storage capacity of electric batteries. The OPTEMUS project proposes to tackle this bottleneck by leveraging low energy consumption and energy harvesting through a holistic vehicle-occupant-centred approach, considering space, cost and complexity requirements. Specifically, OPTEMUS intends to develop a number of innovative core technologies (Integrated thermal management system comprising the compact refrigeration unit and the compact HVAC unit, battery housing and insulation as thermal and electric energy storage, thermal energy management control unit, regenerative shock absorbers) and complementary technologies (localised conditioning, comprising the smart seat with implemented TED and the smart cover panels, PV panels) combined with intelligent controls (eco-driving and eco-routing strategies, predictive cabin preconditioning strategy with min. energy consumption, electric management strategy). The combined virtual and real-life prototyping and performance assessment in a state of the art, on-the-market A-segment electric vehicle (Fiat 500e) of this package of technologies will allow demonstrating a minimum of 32% of energy consumption reduction for component cooling and 60% for passenger comfort, as well as an additional 15% being available for traction, leading to an increase of the driving range in extreme weather conditions of at least 44 km (38%) in a hot ambient (\35C and 40% rH) and 63 km (70%) in a cold ambient (-10C and 90% rH).

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC5-13-2016-2017 | Award Amount: 7.71M | Year: 2016

Scandium (Sc) is one of the highest valued elements in the periodic table and an element which is usually grouped in REEs as it shares many characteristics with Yttrium. Scandium technological applications are unique, as it is a key component in producing Solid Oxide Fuel Cells (Scandia-Stabilized-Zirconia solid electrolyte layer) or high strength Aluminum alloys used in aerospace and 3D printing applications (SCALMALLOY). Yet Scandium supply is limited due to its scarcity and the high cost of its production, which currently takes place in Asia and Russia. Europe has no production of Scandium, but is home to many Sc industrial end-users (Airbus, II-VI, KBM Affilips and others). In fact end-users like Airbus, are not deploying their Sc applications due to the lack of a secure Sc supply. The SCALE project sets about to develop and secure a European Sc supply chain through the development of technological innovations which will allow the extraction of Sc from European industrial residues. Bauxite Residues from alumina production (5 Million tons on dry basis per year in Europe) and acid wastes from TiO2 pigment production (1.4 Million tons on dry basis per year in Europe) have Sc concentrations which are considered exploitable, given a viable extraction technology. SCALE develops and demonstrates the value chain starting from residue and finishing to high tech end-product. In more detail: SCALE develops innovative technologies that can extract economically and sustainably Sc from dilute mediums (<100 mg/L) and upgrade them to pure oxides, metals and alloys at lower energy or material cost. SCALE extracts along with Sc all other REEs found in the by-products (AoGs BR on an annual base contain 10% of the European REE raw material imports) The industrially driven SCALE consortium covers the entire Sc value chain with 7 major European industries and further features 8 academic and research institutes and 4 engineering companies with track records in RTD.

Agency: European Commission | Branch: FP7 | Program: JTI-CP-ARTEMIS | Phase: SP1-JTI-ARTEMIS-2011-5;SP1-JTI-ARTEMIS-2011-1 | Award Amount: 24.44M | Year: 2012

According to a recent forecast published by ABI Research , a fast growth of the market of Advanced Driving Assistance Systems (ADAS) is foreseen in the next five years. For example, in 2016 the overall annual market for Lane Departure Warning systems is expected to reach 22 million units/year (corresponding to 14,3 billion dollars). This market growth will be possible only through the reduction of costs of components as well as the seamless integration of different functions in the same architecture. Since the market will include also low volume vehicles, there will be also a strong need to reduce development costs. Electric vehicles will be an additional catalyst for the ADAS market. The absence of engine noise requires the introduction of new means to protect vulnerable road users from these vehicles. On the other hand, electric vehicles can easily support (semi)automatic functions (such as parking manoeuvres and Stop&Go). To manage the expected increase of function complexity together with the required reduction of costs (fixed and variable) DESERVE will design and build an ARTEMIS Tool Platform based on the standardisation of the interfaces, software (SW) reuse, development of common non-competitive SW modules, and easy and safety-compliant integration of standardised hardware (HW) or SW from different suppliers. With innovative design space exploration (DSE) methods system design costs can be reduced by more than 15%. Hence, DESERVE will build an innovation ecosystem for European leadership in ADAS embedded systems, based on the automotive R&D actors, with possible applications in other industrial domains. Since the purpose of ADAS functions is also to support the driver, an advanced human-centred design strategy will be integrated in the Tool Platform. Therefore, the developed applications will provide natural and friendly support to the driver, with proper levels of overall functional safety also during complex or emergency manoeuvres. - - - Version approved by the JU on 14/07/2015

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: KBBE-2009-1-2-05 | Award Amount: 9.72M | Year: 2010

DROPS will develop novel methods and strategies aimed at yield maintenance under fluctuating water deficit and at enhanced plant water-use efficiency. We deal with high genotype x environment interaction in the field (any trait can have positive, negative or no effect depending on drought scenarios) with an approach combining Physiology, Genetics, field testing and Ecophysiological modelling. The project targets four traits : seed abortion, vegetative growth maintenance, root system architecture and transpiration efficiency. It deals with maize and durum wheat, plus bread wheat and sorghum for specific tasks. DROPS will: - Develop new screens for identifying drought tolerant genotypes, from phenotyping platforms to the field with indicators which are (i) stable characteristics of genotypes with high heritability in phenotyping platforms (ii) based on novel knowledge (e.g. combinations of metabolite concentrations, sensitivity parameters of models or hormonal balances) (iii) genetically related to target traits and able to predict genotype performance in the field via simulation and/or statistical models. - Explore the natural variation of the four target traits by (i) linking the target traits to physiological pathways, genes or genomic regions (ii) assessing the effects of a large allelic diversity for the four target traits via association genetics. - Support crop improvement strategies by developing methods for estimating the comparative advantages of relevant alleles and traits in fields with contrasting drought scenarios. This will be performed via field experiments and by developing a new generation of crop model able to estimate the effects of alleles on crop growth, yield and water-use efficiency Results and methods will be diffused (i) to breeders via the participation of seed companies and a partnership with a breeder association, (ii) to scientists and students via academic publications, and via practical courses and virtual courses in its website.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-20-2015 | Award Amount: 2.75M | Year: 2015

OBJECTIVES: Build on multi-discipline research (e.g., human-centred methodology integrates cognitive models, ergonomics, understanding of workers well being) to accelerate how we identify, acquire and exploit skills valued by industry. Get high take-up by early adopters (e.g., in manufacturing). Augment training in situ with live expert guidance, a tacit learning experience and a re-enactment of the expert, in knowledge-intensive environments where effective decision making, often in new situations, has high impact on effectiveness in production. Bring learning content and technical documentation to life via task-sensitive Augmented Reality (AR). Make final products flexible for workplace integration via industry-standard repositories and toolkits. HOW: Wearable TEL platform enhances human abilities to acquire procedural knowledge by providing a smart system that directs attention to where it is most needed. An extensive audit of industry procedures, policies and participatory design methods will define the main facets of the platform. User test cycles will refine prototypes and deliverables. Existing wearable smart devices and sensors will be tailored to provide an innovative solution for content delivery and measurement of user performance. Comparative tests, stakeholders review and leading the IEEE AR group will secure high-standard academic and industrial outputs. RELEVANCE to work programme: WEKIT is strongly aligned with EU job/training policies (e.g., Grand Coalition for Digital Jobs). It enhances the industrial value chain, reduces fragmentation/cost and improves efficiencies with impact regarding speed and scale in production. Looking ahead: roadmap shows safe skill pathways for use of TEL in changing industrial landscapes (e.g. smart machine-to-machine (M2M) knowledge-sharing). Smarter products and services will improve workflows, enhancing (re)training of workers whose skill sets need upgrading after Industry 4.0.

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: GV-11-2016 | Award Amount: 3.50M | Year: 2017

The FUTURE-RADAR project will support the European Technology Platform ERTRAC (the European Road Transport Research Advisory Council) and the European Green Vehicle Initiative PPP to create and implement the needed research and innovation strategies for a sustainable and competitive European road transport system. Linking all relevant stakeholders FUTURE-RADAR will provide the consensus-based plans and roadmaps addressing the key societal, environmental, economic and technological challenges in areas such as road transport safety, urban mobility, long distance freight transport, automated road transport, global competitiveness and all issues related to energy and environment. FUTURE-RADAR will also facilitate exchange between cities in Europa, Asia and Latin America on urban electric mobility solutions. The FUTURE-RADAR activities include project monitoring, strategic research agendas, international assessments and recommendations for innovation deployment as well as twinning of international projects and comprehensive dissemination and awareness activities. Overall it can be stated that FUTURE-RADAR provides the best opportunity to maintain, strengthen and widen the activities to further develop the multi-stakeholder road transport research area, for the high-quality research of societal and industrial relevance in Europe.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: KBBE-2008-3-1-05 | Award Amount: 4.40M | Year: 2009

The CoMoFarm project will establish high-yielding production systems for pharmaceutical and industrial proteins based on plants, plant tissue and plant cells. The aim is to develop systems in which both the production host and the product itself show consistent yield and quality. The project will include a comparison of four alternative systems hydroponic plants, root cultures, moss and suspension cells, and will involve the evaluation of different species, strain and process optimization, scale-up, downstream processing, protein characterization and process evaluation in terms of regulatory compliance. As well as furthering the development of an emerging production technology, the project will incorporate numerous innovative elements such as in-process monitoring and automation of environmental parameters to maintain a consistent environment and optimize protein yield and homogeneity, novel downstream processing technologies and innovative bioreactor and hydroponic designs to maintain plant health and ensure production according to good manufacturing practice. This project will have an immense impact on the biopharmaceuticals industry, by allowing SMEs interested in molecular farming to develop plant-made pharmaceuticals without worrying about regulatory constraints or poor investment prospects. This will go a long way to establishing molecular farming as a feasible industry within Europe, and will open new revenue streams for companies currently not interested in (or aware of) molecular farming, e.g. horticulture companies and nurseries. The cost of drugs will also begin to fall, which will positively re-enforce the benefits of plants and lead to greater growth in the market.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC5-11c-2015 | Award Amount: 7.99M | Year: 2016

A key EU policy aims to reduce the Union dependency on raw materials imports, in particular (candidate) Critical Raw Materials that are vital for the EU innovative technologies. Topic SC5-11c-2015 scope focuses on developing new highly-automated technological sustainable solutions for deep mining in the sea bed combined with in-situ processing of minerals. An existing but challenging raw material resource concerns polymetallic nodules. These round to elongated concretions of 115 cm diameter form on sediment-covered deep-sea plains in all oceans between 4-6000m water depth. The challenge to harvest and transport the nodules to the EU shore is taken on by Blue Nodules. The governing project principle is: industrial viability within the context of a realistic and technical, economic and environmentally balanced business case for the complete Polymetallic Nodules value chain of mining, processing and valorisation. Blue Nodules will develop and test to TRL6 maturity a new highly-automated and technologically sustainable deep sea mining system. Key features are: an annual production capability of 2 Million Tons nodules in water depths up to 6000m, in-situ processing of the nodules and intrinsic safe working conditions. Technical WPs are dedicated to subsea harvesting equipment & control technology, in-situ seafloor processing of polymetallic nodules and sea surface, land operations & processes. A dedicated WP focuses on environmental issues and on an Environmental Impact Assessment (EIA). A WP setting requirements and assessing the developed technology controls the entire work plan structure. High credibility is obtained by linking the project work to a nodule field licence owned by a project partner and located in the most promising known nodule deposit: the Clarion Clipperton Zone. The project consortium contains 14 leading industry and research partners from 9 EU member states. The project duration is 48 months, the required funding amounts to 8 Million.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: GC.SST.2012.3-1. | Award Amount: 4.29M | Year: 2012

The trend towards increasing transport demand - prerequisite for economic growth - is still challenging the European transport system. On the other hand Europe aims to reduce emissions dramatically. A crucial measure achieving this ambitious aim is to lower transport emissions by increasing the share of inherently more resource-friendly modes of transport. The Intelligent Transport System for Innovative Intermodal Freight Transport (TelliSys) will actively promote the EUs objective of optimizing the performance of intermodal logistic chains and will provide smooth and cooperative interactions between different modes of transport. Scientific aim is to develop an intelligent transport system that is applicable for road (in line with Directive 96/53/EC), rail, short sea and inland shipping, which consists of a modular set of volume-optimised and traceable MegaSwapBoxes (MSB), an adapted trailer and a tractor for the road transport. Ideas and contributions from the consortium together with the advice of outstanding key players of the transport business guarantee the holistic approach and market acceptance of the project outcomes. TelliSys is the follow-up of the successful TelliBox project and the now modular MSB will be based on the unique selling propositions like stackability, three openable sides, three meters loading height, trimodality, pallet wide and cargo security. In addition, the new developed tractor will provide an extra low fifth wheel height (low deck) designed for volume-optimised road transport and the adapted trailer will be flexible to transport conventional loading units as well as the new MSBs. Within TelliSys an interdisciplinary European consortium of experts in the field of freight forwarding, manufacturing and science will deliver concepts, prototypes and a proof of concepts via extensive test runs. A complementary bundle of scientific evaluation methods, profitability calculations and risk mitigation actions will guarantee the project succes

Agency: European Commission | Branch: FP7 | Program: MC-ITN | Phase: FP7-PEOPLE-2013-ITN | Award Amount: 3.78M | Year: 2013

The Spintronics in Graphene Training project (SPINOGRAPH) will create a European network of experts providing state-of-the-art training for early stage researchers (ESR) and Experienced Researchers (ER) in the blooming field of Spintronics in Graphene. The huge success of spintronics in metals which, starting from the pioneering discovery of Giant Magnetoresistance (GMR), has revolutionized the magnetoelectronics industry, and the remarkable progress in the fabrication of graphene devices, have naturally led to the exploration of spintronic devices based on graphene. The primary objective of this network is to significantly enhance the employment prospects of E(S)Rs by: (a) choosing a scientific subject that has both a solid ground and an enormous scientific and industrial potential, (b) engaging E(S)R in research projects in world-leading laboratories, including those of 2 Nobel laureates and in collaboration with small and medium enterprises in the emerging industry of graphene (c) ensuring that all researchers receive scientific and complementary skills training that is critical both to academia and industry.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: SST.2008.1.1.2. | Award Amount: 4.31M | Year: 2009

The reluctance of OEM worldwide to extend electric drive applications to the private customers depends partly from considerations on customer acceptance (limited range in the case of EV, long charging time after depletion of the battery, cost), but also from the increased reliability and life span that private customers are entitled to expect. The first goal of HELIOS project is to evaluate electrochemical couples whose lower voltage window matches perfectly with the stability window of the electrolyte, which should guarantee an outstanding steadiness of the performance during ageing, and an intrinsic excellent safety. The items evaluated by the project are: performance, safety, life, recyclability and global cost. Another issue addressed by the project is the definition of a European standard for safety and life (cycle/storage) tests, adapted to High Energy applications such ad EV, PHEV and Heavy Duty Hybrid Truck. The project partners include six OEMs, one battery manufacturer, test Institutes/Universities and one recycler.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: AAT.2008.2.2.2. | Award Amount: 3.56M | Year: 2009

The TITAN project will analyse the current Turnaround process to detect gaps and to study the influence of external actors, specially the effect of land-side process like passenger flow or baggage handling. A concept shall be defined for this improved process, which will be modeled and validated using the most appropriate platform. Using the validated concept, a decision-making support tool for the airlines will be developed to better manage the incidences that may occur during the turnaround process. TITAN will aim at raising common awareness of the impact of each stakeholder performance, including landside, in the global process performance and stressing the importance of making the conditions of transfer of responsibility among actors much more detailed and explicit.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: NMP.2011.1.2-3 | Award Amount: 4.96M | Year: 2012

The shortage of drinking water in many regions on the planet constitutes a real problem and hazard. The use of seawater, brackish water and wastewater for human consumption is not a new concept. In spite of the success of membrane technology in water reclamation, membrane separation systems suffer from a serious problem: membrane fouling. The main downside is an inevitabe increase in operation and maintenance costs as well as an adverse effect on the lifespan of the membrane (harsh cleaning treatment). LbLBRANE is an ambitious project ensuring competent input right from the membrane concept down to lab-scale production and optimisation before scaling-up in pilot plants for end users. LbLBRANE applies novel nanotechnology tools, namely the layer-by-layer (LbL) technology to develop a versatile and generic procedure for the fast fabrication of low-cost, stable, chemical-resistant polyelectrolyte membranes. The LbL technology is the way to go for a bottom-up nano-engineered membrane whereby the modification is performed stepwise in a controlled manner - the thickness can be finely tuned by the number of layers deposited, the architecture of the film can be compartmentalised by incorporating functional species (polyelectrolyte as well as nanoparticles with specific functions, such as antibacterial properties) and the morphology of the film can be modulated via the pH, charge density and type of polyelectrolyte pairs to create pore size (hence permeability) tailored according to the specific need of the membranes. Our concern is focused towards high performance, regenerable membranes which could be cleaned in-situ and hybrid membranes with extremely high flux with high permselectivity and mechanical robustness. The ultimate aim is towards implementation of LbL on large industrial scale, from module design and construction to end user, especially for water reuse and metal/acid recovery.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: BIOTEC-1-2014 | Award Amount: 7.06M | Year: 2015

P4SB is about the utilization of the conceptual and material tools of contemporary Synthetic Biology to bring about the sustainable and environmentally friendly bioconversion of oil-based plastic waste into fully biodegradable counterparts by means of deeply engineered, whole-cell bacterial catalysts. These tools will be used to design tailor-made enzymes for the bio-depolymerization of PET (polyethylene terephthalate) and PU (polyurethane), but also for the custom design of a Pseudomonas putida Cell Factory capable of metabolizing the resulting monomers. Pseudomonas putida will undergo deep metabolic surgery to channel these diverse substrates efficiently into the production of polyhydroxyalkanoates (PHA) and derivatives. In addition, synthetic downstream processing modules based on the programmed non-lytic secretion of PHA will facilitate the release and recovery of the bioplastic from the bacterial biomass. These industry driven objectives will help to address the market need for novel routes to valorise the gigantic plastic waste streams in the European Union and beyond, with direct opportunities for SME partners of P4SB spanning the entire value chain from plastic waste via Synthetic Biology to biodegradable plastic. As a result we anticipate a completely biobased process reducing the environmental impact of plastic waste by establishing it as a novel bulk second generation carbon source for industrial biotechnology, while at the same time opening new opportunities for the European plastic recycling industry and helping to achieve the ambitious recycling targets set by the European Union for 2020.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: NMP-2007-3.2-1 | Award Amount: 5.02M | Year: 2008

Machine tools are a key component in industrial production processes as they provide an important contribution to the added value of manufactured products. They are based on mechanical structures conceived as a result of optimised designs in order to achieve the required performances for each one of the machining processes. The relatively recent irruption of mechatronic concepts, which take advantage of the incorporation of active devices and certain degree of intelligence to the mechanical structures, allowed to break limits and provide increased performances to the base mechanical structures and hence to machine tools. The present project proposes a new approach in the exploitation of active intelligent devices integrated in machine tools. The main idea is to equip a machine-tool with a variety of active intelligent devices, which would be intelligently activated and parameterised in order to change the overall configuration and performances. This way, the machine would be rapidly configured to the different and even conflicting conditions or performances required for the target machining operation (e.g. roughing operation on hard steel, requiring a stiff machine versus high speed machining on aluminium, which requires a light highly dynamic machine). As result of this approach, a base mechanical structure equipped with an assortment of intelligent devices could be configured as a different machine depending on the selected gadgets, so that the resulting characteristics and performances of the machine could be adapted to those required by each particular machining operation, this is a chameleon-like machine tool concept. The main objective of the project is to develop a new concept of machine tool so that it is completely configurable and adaptive, based in mechatronic devices, in order to cope with multiple and even opposed requirements of the machining operations, so that the range of target machining operations is dramatically increased.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: MG-5.1-2014 | Award Amount: 5.99M | Year: 2015

The overall aim of ELIPTIC is to develop new use concepts and business cases to optimise existing electric infrastructure and rolling stock, saving both money and energy. ELIPTIC will advocate electric public transport sector at the political level and help develop political support for the electrification of public transport across Europe. ELIPTIC looks at three thematic pillars: Safe integration of ebuses into existing electric PT infrastructure through (re)charging ebuses en route, upgrading trolleybus networks with battery buses or trolleyhybrids and automatic wiring/de-wiring technology upgrading and/or regenerating electric public transport systems (flywheel, reversible substations) Multi-purpose use of electric public transport infrastructure: safe (re)charging of non-public transport vehicles (pedelecs, electric cars/ taxis, utility trucks) With a strong focus on end users, ELIPTIC will analyse 23 use cases within the three thematic pillars. The project will support uptake and exploitation of results by developing guidelines and tools for implementation schemes for upgrading and/or regenerating electric public transport systems. Option generator and decision-making support tools, strategies and policy recommendations will be created to foster Europe-wide take up and rollout of various development schemes. Partners and other cities will benefit from ELIPTICs stakeholder and user forum approach. ELIPTIC addresses the challenge of transforming the use of conventionally fuelled vehicles in urban areas by focusing on increasing the capacity of electric public transport, reducing the need for individual travel in urban areas and by expanding electric intermodal options (e.g. linking e-cars charging to tram infrastructure) for long-distance commuters. The project will strengthen the role of electric public transport, leading to both a significant reduction in fossil fuel consumption and to an improvement in air quality through reduced local emissions.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: GC.SST.2013-4. | Award Amount: 22.22M | Year: 2013

Electrification of the public transport is a raising trend in Europe, and electric buses are soon expected to enter markets as one of the most interesting options for matching urban environmental targets. Electrification is driven by both economics and politics. However, although technology is not yet fully matured and ready for wide commercialisation, a large demonstration project will facilitate the market up-take of electric buses in Europe. Furthermore, as unambiguous and extensive information about overall effects of electrified bus systems and related needs for changes on infrastructure do not exist today, UITP sees its objectives and those matching perfectly, and this led UITP to build a consortium of 40 partners, who were already considering their actions along this theme, and to collectively design the 42-months demonstration project ZeEUS Zero-Emission Urban Bus Systems. ZeEUS project focus on the todays challenge in the electrification of bus system, the extension of the fully-electric solution to a wider part of the urban network. This goes through the development of electric vehicles of large capacity, and the creation of an infrastructure capable of providing the required charging energy, operated according to non-disruptive and grid-balancing principles. The ZeEUS project will cover innovative electric bus solutions with different types of electrical power-train systems. Full-electric battery-based busses will be demonstrated in five locations (Barcelona, Bonn, Muenster, Plzen and Rome), whereas plug-in hybrid or range-extender type of power-trains will be demonstrated in three sites (London, Glasgow and Stockholm). The lifetime of project ZeEUS is long enough to collect sufficient amount of statistically valid data and make comprehensive analysis to deliver meaningful lessons learned, guidelines and provide feedback to the R&D activity of manufacturers and suppliers to make technology mature for wide commercialisation.

Agency: European Commission | Branch: FP7 | Program: CP-CSA-Infra | Phase: INFRA-2008-1.1.1 | Award Amount: 9.65M | Year: 2009

CHARISMA is an Integrated Infrastructure Initiative that brings together 22 leading European institutions developing research on artwork materials and their deterioration finalised to the conservation of cultural heritage. The consortium has the objective to optimise the use of infrastructures through a coordinated program of transnational access, joint research and networking activities. Transnational access offers applicants opportunities to exploit the services of three different and complementary groups of facilities, embedded in a multidisciplinary environment involving material science and artwork conservation/restoration. They are: i) a group of six archives containing a huge amount of analytical data, hosted by the most prestigious European museums and institutions developing safeguard and conservation of cultural heritage; ii) a set of advanced portable instrumentation for in-situ non-invasive measurements in the same site where the artworks are located or exhibited; iii) two platforms, one in France and one in Hungary, where large scale facilities are coupled to a set of medium scale instrumentations, open to users for the most advanced studies on artwork materials and their alterations. Research is devoted: i) to improve access to databases exploiting digitalisation of data and their harmonisation; ii) to design and set-up innovative instrumentations, for in-situ 2D and 3D examinations of artworks, and new cleaning techniques; iii) to develop new methodologies for the study of organic materials and their distribution in micro-samples or directly at the surface of the object. Through networking, the way infrastructures are working is improved, harmonising methodologies and best practices in analysis and conservation, pursuing the establishment of a multidisciplinary synergic working method, based on shared use of knowledge and resources.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: GC.NMP.2013-1 | Award Amount: 8.40M | Year: 2013

A lifetime of 4000 cycles at 80 % DOD and an energy density of 250 Wh/kg is a target for automotive batteries. The Batteries2020 project takes several steps to increase lifetime and energy density of large format lithium ion batteries towards these goals. Our approach is based on three parallel strategies: 1) highly focused materials development; 2) understanding ageing and degradation phenomena; and, 3) routes to reduce battery cost. We will improve cathode materials based on nickel/manganese/cobalt (NMC) oxides. Such materials have a high chance to be up-scaled and commercialized near-term. Only then, cell development efforts can be translated from pilot to mass production, a prerequisite for qualification in the automotive industry. We will start with state of the art cells and will develop two improved generations of NMC materials and cells towards high performance, high stability and cycleability. A deep understanding of ageing phenomena and degradation mechanisms can help to identify critical parameters that affect lifetime battery performance. This identification helps effectively improving materials, system and the development of materials selection criteria. However, ageing and degradation mechanisms have multiple reasons and are complex. We propose a realistic approach with a combined and well organised Consortium effort towards the development of robust testing methodology which will be improved in several steps. Combined accelerated, real tests, real field data, post-mortem, modelling and validation will provide a thorough understanding of ageing and degradation processes. Battery cost is a major barrier to EV market. Second life uses can reduce battery costs. We will analyse the potentiality of reusing and recycling batteries for providing economic viable project outputs. Our consortium combines a wide range of expertise from materials development and battery production to lifetime characterisation and viability and sustainability of the chosen appro

Agency: European Commission | Branch: FP7 | Program: MC-ITN | Phase: FP7-PEOPLE-2013-ITN | Award Amount: 4.09M | Year: 2014

Improving Childrens Auditory REhabilitation (iCARE) Communication through language is vital to develop and maintain everything around us. By 15 years of age, about 5 out of 1000 children suffer from a moderate, severe or profound hearing impairment that can potentially affect communication, learning, psychosocial development and academic achievement if not appropriately handled. The EU promotes the active inclusion and full participation of disabled people in society. However, full active inclusion in an oral society can only be achieved through cooperation and involvement across disciplines (language, psychology, audiology, engineering, special education,). It is therefore of fundamental importance to approach the inclusion of children with hearing impairment in an interdisciplinary manner, and to train future experts to adopt such principles in their research and practice. The objectives of improving Childrens Auditory REhabilitation (iCARE) are twofold: 1) to provide training create a new generation of researchers capable of exploiting the synergies between different disciplines to optimize spoken communication in children with hearing impairment, and 2) to combine research across disciplines to develop novel methods, training skills and procedures for improving auditory rehabilitation. iCARE is an international and interdisciplinary consortium from academia, industry and socio-economic agencies. The proposed training consortium is unique because the partners are specialized in a variety of disciplines, both technical and non-technical, all of utmost importance to the core issue: optimizing inclusion of children with hearing impairment in an oral society through evidence-based research. The consortium will provide comprehensive training of fellows to become communication experts, and enable the development of novel methods, tools and evaluation material that will suit the evolving needs of children with hearing impairment in a holistic manner.

Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: NMP.2013.2.3-2 | Award Amount: 880.60K | Year: 2013

Scope of this proposal is to establish a network of stakeholders - an Integrative Computational Materials Engineering expert group (ICMEg) - aiming at the creation of an open, global standard for information exchange between a heterogeneous variety of commercial and academic simulation tools. The vision of the ICMEg proposal is a new strategy of materials and process development, where a variety of academic and commercial simulation tools present and future can be easily combined across different process steps and bridging several length scales in a plug&play type architecture being based on an object oriented, standardized information exchange. Multi-scale in this context covers electronic, atomistic,mesoscopic and continuum models The Mission of ICMEg is to establish and to maintain a network of contacts to (1) simulation software providers around the world (2) governmental and international standardization authorities (3) ICME type users of simulation software (4) different associations in the area of materials and processing (5) academic developers of simulation software to define an ICME language in form of an open and standardized communication protocol to stimulate knowledge sharing in the field of multiscale materials design to communicate this standard worldwide to make it widely accepted to discuss and to decide about future amendments to the initial standard to establish a legal body for a sustainable further development The Approach of ICMEg to realize both its vision and its mission is to create a global network of all stakeholders in the area of ICME software and users by identifying all actors in the field of ICME related simulations creating an inventory of these stakeholders networking of all identified stakeholders in two international conferences composing a directory of all available simulation approaches establishing a common language for standardized information exchange secure sustainable further the common language by foundation of an international association identifying missing models and functionalities and proposing a roadmap for their development

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: NMP.2012.4.1-1 | Award Amount: 13.78M | Year: 2013

With numerous European industries heavily depended on imported REE raw materials, there is a need for EU to secure a viable supply of REE minerals as well as develop from the ground up the currently non-existent European REE extraction and processing industry. The goal of the EURARE project will be (i) to characterize the potential REE resources in Europe; and (ii) to research, develop, optimize and demonstrate technologies for the efficient and economically viable exploitation of currently available European REE deposits with minimum consequences to the environment. In the EURARE project, the mineral processing technologies currently used for the REEs minerals will be investigated for representative European REE ores, with a tendency for improvement by adopting new approaches for the complete ore utilization and minimal environmental consequences, establishing integrated mineral processing systems, with zero or close to zero tailings. The current state-of-the-art processes for REE extraction follows complicated, energy and resource intensive technologies. The EURARE project aims in developing novel cost-effective and resource-efficient REE extraction process, tailored specifically for European REE ore deposits as well as for European health, safety and environmental protection standards. As an added value to the work already described, EURARE will seek to demonstrate new sources for REE exploitation from industrial metallurgical waste which will not only be financial lucrative but will minimize the overall environmental footprint of the primary European metallurgical industry. Special attention in all cases will be given in health, safety and social issues, in light of naturally occurring radioactive elements. At the end of the EURARE project it is expected that a novel sustainable exploitation schema for Europes REE deposits will have been established

Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: SST.2013.6-1. | Award Amount: 2.05M | Year: 2013

Maritime Europe Strategy Action (MESA FOSTER WATERBORNE), main strategic objective (in line with WATERBORNE-TP) is to strengthen the effectiveness of the research and innovation capacities of the European maritime industry, by: - Optimization of the European maritime RDI strategies - Improvement of the stakeholders network, of the dissemination, of the use of the research results, and increasing the visibility of the R&I findings - Fostering the definition of the maritime R&I transport policies MESA, is (1) providing support to the WATERBORNE TP work, enlarging and maintaining it, (2) identifying 4 major themes (implemented via Thematic Technology Groups on Energy Efficiency, Safety, Production, E-Maritime) performing an in-depth analysis and assessment of the achievements at EU and National level, to foster future strategic lines in research and innovation, (3) updating the strategic research agenda and creating an innovation agenda contributing to close the gaps between research and market uptake, (4) enhancing a network for the exchange of ideas and priorities, (5) acting as major player for dissemination raising waterborne value chain profile and visibility in Europe. Foresight activity will provide market, societal and regulatory trends studies, contributing to transport RDI policies. A Integration Group will issue Strategic documents for the waterborne sector: VISIONS2030, Strategic Research Agenda, Innovation Agenda, Implementation Plan, homogenizing findings of the Thematic Technology Groups and the Foresight. A comprehensive communication strategy will be implemented including coverage of the TRA2014, 2016, Technology Workshops, Major Conferences, Newsletter, Brokerage Events, Show Cases of successful projects, TRIP liaison, etc. MESA involves 28 partners, (industrial, research, education, associations) ensuring the widest possible participation accustomed to work together since many years, in the majority of EU projects and in the WATERBORNE-TP.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: NMP-2007-3.5-2 | Award Amount: 10.80M | Year: 2008

The proposed project aims at creating new high precision manufacturing technologies to respond cost-effectively and eco-friendly to the mass customization paradigm within the production of complex shape micro parts, embedded systems and miniaturized products at micro/meso-scale level (from 10 to 10.000 micron range). The main objective of Integ-micro is the research and development of new hybrid and reconfigurable multitasking machines and combined processes based on integration of different ultra high precision techniques for the generation of 3D complex shape microcomponents made from different kinds of materials. Multitasking micromachining can be best described as the ability to perform multiple machining operations in one workholding configuration. This guarantees greater accuracy, reduced handling and plant area, faster throughput and increased productivity. The availability of several machining technologies on a single machine allows important synergies between the different machining methods. For instance, combining machining by chip removal and laser micro machine will provide the capability to remove (by laser) the burr remaining from the previous chip removal operation. Alternatively, chip removal machining and laser LIGA technique can be combined in order to machine small components that could not be produced otherwise. The project will bring high added value thanks to the minimum time loss in setting new production lines for strategic products through short reconfiguration time and reduced ramp-up phase. The above goals will be reached exploiting methods of sustainable production, including downscaling of machine size (machine size reduced of 5 times at least), new process chain approaches for dramatically reduced processing times and eco-friendly processes like dry ultra-high speed cutting (UHSC) at micro-meso domain (eliminate the use of cutting fluid to get the target of zero waste emission).

Agency: European Commission | Branch: H2020 | Program: IA | Phase: BIOTEC-3-2014 | Award Amount: 11.39M | Year: 2015

Oxygen functionalities are key functional groups in many of todays chemicals and materials. The efficient introduction of oxygen-functionalities into raw materials are key chemical transformations in bulk and fine chemicals. Innovative bio-catalytic oxidation routes using molecular oxygen (from air) under benign and mild (pH) conditions such as ambient temperature and pressure can greatly improve the sustainability and economics of processes, but were so far mainly been applied in the pharma segments. In this segment, the enzyme-catalyzed step often represents the highest added value and the high price of the end-product (> 1000/kg) justifies less than optimal enzyme production and limitations in its catalytic efficiency. In order to achieve the widening of industrial application of enzymatic bio-oxidation processes to also larger volume but lower price chemical markets, ROBOX will demonstrate the techno-economic viability of bio-transformations of four types of robust oxidative enzymes: P450 monooxygenases (P450s), Baeyer-Villiger MonoOxygenase (BVMOs), Alcohol DeHydrogenase (ADH) and Alcohol OXidase (AOX) for which target reactions have already been validated on lab-scale in pharma, nutrition, fine & specialty chemicals and materials applications. ROBOX will demonstrate 11 target reactions on large scale for these markets in order to prepare them for scale up to commercial-scale plants. ROBOX is industry-driven with 2 major industrial players and 6 SMEs. It will assess the potential of technologies applied to become platform technologies technologies (multi-parameter screening systems, computational methodologies, plug bug expression systems) for broad replication throughout the chemical industry. The markets addressed within ROBOX represent a joint volume of over 6.000 ktons/year. The introduction of bio-oxidation processes is expected to bring substantial reductions in cost (up to -50%), energy use (-60%), chemicals (-16%) and GHG-emissions (-50%).

Agency: European Commission | Branch: FP7 | Program: MC-ITN | Phase: PEOPLE-2007-1-1-ITN | Award Amount: 3.00M | Year: 2009

All aspects of speech processing are rapidly growing in commercial importance. A leading market analyst reports 129.8 million USD were generated by speech products in North America in 2004, but predicts these revenues will increase to nearly one billion USD by 2011. In order to accelerate the rate of advance in speech technology, a new elite of researchers are required who are well-versed in all aspects of speech processing, as opposed to the narrowly-concentrated specialists who are currently the norm. Educating such an elite class of researchers will be a primary goal of the SCALE, Speech Communication with Adaptive Learning, Initial Training Network. SCALE will be concerned with adaptive learning approaches to all areas of speech processing, with particular focuses on automatic speech recognition and synthesis, signal processing, human speech recognition, and machine learning. The primary goal of SCALE is to create an environment that will foster synergistic cooperation between researchers in each of the aforementioned disciplines. In particular, SCALE has three principal scientific objectives: 1. To bridge the gap between speech recognition and speech synthesis; 2. To bridge the gap between human and automatic speech recognition; 3. To bridge the gap between signal processing and adaptive learning. We plan to assess the improvements in these core technologies achieved in the course of the project through regular evaluations on standard benchmark tasks. We will also demonstrate the effectiveness of the interdiscplinary approach to research in speech processing proposed here through a series of high quality publications at international conferences and in prestigious journals. Finally, we propose to build cooperation between academia and industry through the inclusion of two major industrial partners in the consortium, whose presence will ensure the research training contributes directly to the next generation of speech products.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2013.6.5 | Award Amount: 24.19M | Year: 2014

AdaptIVe will enhance the performance and improve the acceptance of automated driving of cars and trucks. The project develops new and integrated automated functions to improve traffic safety by minimizing the effects of human errors and to enhance traffic efficiency by smoother flows and reduced congestion.The approach is based on a shared control concept, assuring proper collaboration between the driver and the automation system. This is realised using cooperative vehicle technologies, advanced obstacle sensors and adaptive schemes where the level of automation dynamically responds to the situation and driver status.The project will demonstrate and evaluate eight advanced vehicles seven cars and one truck with various combinations of automated functions. These implementations will be based on the needs of different environments and levels of traffic complexity, including motorways, urban scenarios and close-distance manoeuvres. Several common features developed in these vehicles will establish fundamental building blocks for the future exploitation of automated driving, in terms of architecture, fault-tolerance, and human factors. Communication technologies will be employed as a key enabler of highly automated schemes supporting cooperative traffic and improving road safety.In addition to the technological and ergonomic aspects, AdaptIVe will address important legal issues that might impact on the successful market introduction of automated systems; in particular product liability and road traffic laws. It will identify the legal implications for manufacturers and drivers and examine the need for corresponding changes in regulation.By demonstrating these results, AdaptIVe will significantly improve the knowledge base for automated driving and strengthen the position of European industries in the area of Intelligent Vehicles and road safety.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: GC-SST.2010.7-5. | Award Amount: 4.82M | Year: 2010

Increasing energy costs and stringent CO2 emission targets drive the growing market opportunity (and societal need) for fully electric vehicles (EVs). The ELVA project focuses on electric cars for city passengers and urban delivery where traffic volume is high and the impact on the local environment is most significant. Knowledge transfer to other vehicle types will be facilitated by a novel design approach to be developed by ELVA. The change in propulsion technology from internal combustion engines (ICE) to electric powertrains will lead to the integration of new components and systems, while others undergo changes or become obsolete. This opens up new freedom in design and clears the way for new vehicle concepts. ELVA is to deliver results that allow for full exploitation of this new freedom, while responding to changing future market demands. To achieve this key objective, the ELVA project generates, investigates and analyzes innovative design concepts for EVs. It delivers a wide range of advanced modular architectures which enable at least the same high level of intrinsic safety as known from current best in class conventional vehicles at minimal weight, maximised energy efficiency, optimized ergonomics & loading space at affordable costs as well as acceptable levels of comfort and driving performance. In particular ELVA delivers best practices and evidence based design rules for modular lightweight and safe architectures specific to EVs. These practices and design rules will feed into and partially replace existing experience-based design methodologies, which have been developed over more than a century of vehicle design around the internal combustion engine. ELVA will achieve a substantial impact with regard to a greener road transport system and a competitive car industry due to the strong involvement of leading industrial partners including 3 car makers that together are expected to produce a substantial part of all EVs sold in Europe in the next decade.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: AAT-2007-4.1-05 | Award Amount: 6.75M | Year: 2008

ACCENT addresses the relevance to the call 7.1: Aeronautics and Air Transport by Improving Cost efficiency and quality of safety critical aircraft engine components. The manufacture of safety critical rotating components in modern aero engines is by nature very conservative. In order to achieve the required engine performance, thermal and mechanical stresses are pushed to the maximum, which in turn leaves the choice of materials to exotic super alloys. These materials are classed as difficult to machine under normal circumstances, but when added to the changes in mechanical properties which occur naturally from part to part, consequently variable and often unpredictable tool life, and the ever present possibility of random and unexpected process anomalies, machining processes can never be fully optimised. Stringent legislative controls are placed on safety critical component manufacture to ensure that parts entering service will function correctly and safely to a declared service life, and in declaring the service life for such a part, the machinability issues stated above have to be taken into consideration. Hence manufacturing process parameters are often reduced or tools are changed early to ensure part surface integrity. The industry method adopted, is to freeze to process following process qualification to first article inspection, and successful part validation via laboratory examination and testing. Once frozen, no changes to process parameters are permitted without time consuming and costly re-validation. ACCENT will allow the European Aero Engine manufacturers to improve their competitiveness by applying adaptive control techniques to the manufacture of their components. Being able to adapt the machining process to the constantly changing tool and component conditions whilst operating in a multi-dimensional approved process window, processes will be optimised to the prevailing conditions and no longer frozen.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: AAT-2007-1.1-01;AAT-2007-1.1-02 | Award Amount: 7.09M | Year: 2008

All aerodynamic concepts for significant reduction of drag such as laminarisation require slim high-aspect-ratio wings. However, state-of-the-art high lift systems will suffer from the reduced construction space and do not cope with the required surface quality. Thus, SADE (Smart High Lift Devices for Next Generation Wings) develops suitable morphing high lift devices: The seamless smart leading edge device is an indispensable enabler for laminar wings and offers a great benefit for reduction of acoustic emissions, the smart single slotted flap with active camber capability permits a further increased lift. Due to versatile usability both devices also offer aerodynamic benefits by shape adaption in cruise flight. Morphing devices imply the integration of drive systems into tailored lightweight structures and therefore reduce complexity and mass. Furthermore, focussing on electric actuators the energy consumption can be reduced. However, the high elasticity required for efficient adaptability of the morphing structure is diametrically opposed to the structural targets of conventional wing design like stiffness and strength. To find the optimum compromise precise knowledge on target shapes for maximum high lift performance and sizing loads is mandatory. Therefore, SADE comprises all relevant disciplines for the investigation of morphing wings and operates a state-of-the-art virtual development platform. Nevertheless, the focus is clearly set on adaptive structures. SADE builds on available promising concepts for smart structures. The technological realisation and optimisation of these concepts towards the special requirements of full scale systems is the most essential challenge for morphing today. Another challenge results from the aeroelastic condition the structural system is optimised for. Hence, a realistic full scale section of a morphing wing will be manufactured and tested in the TsAGI T101 wind tunnel.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: NMP.2011.4.0-2 | Award Amount: 25.41M | Year: 2011

The mine of the future will exploit mineral raw materials at greater depths than today, requiring completely different approaches compared to todays deep mines, in order to get mineral rights. Only these eco-efficient mines will contribute to improved access to domestic mineral resources, secure the supply of mineral raw materials for Europe and reduce the import dependency. IntelliMine will contribute to realise these concepts of invisible, zero-impact and safe mines. The mine of tomorrow will run an integrated concept. All operations necessary for the eco-efficient provision of the minerals including waste management will be carried out underground. This will drastically reduce the volumes being transported, minimising above ground installations and thus the environmental impact. IntelliMine will develop innovative methods, technologies, machines and equipment for the safe, eco-innovative, intelligent and economical exploitation of mineral raw materials in the EU, including maintenance issues, especially at greater depths. It will investigate autonomous, highly selective mineral extraction processes and machinery based on new sensor technologies as well as innovative concepts for mass flow management and transportation. Such investigations have to be accompanied by rock mechanics and ground control issues as well as health, safety and environmental issues. The concept of an invisible, zero-impact mine requires a refined process underground that selectively extracts the minerals and therefore reduces waste production closer to the mineralisation. Therefore improved near to face processing methods including backfill procedures need to be developed. The necessary level of automation in mining operations can only be achieved by reaching a higher level of integration in all parts of a mine. Fully integrated underground technologies and processes for diagnosis and extraction as well as communication, health and safety issues are the key for the success of the concept.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: AAT.2012.1.4-2. | Award Amount: 30.14M | Year: 2012

Future aero engines will need to be more efficient and contribute to the reduction on environmental impact of air transportation. They must reach some standards of performance by reducing emissions and creating some savings on operation costs. EIMG consortium has launched since several years some initiatives to develop future engines in the frame of the European Committee research programmes. Within different project such as DREAM, VITAL, NEWAC or LEMCOTEC, EIMG is ensuring the development of innovative technologies in order to further reduce the fuel burn, emissions and noise. In order to ensure the technological breakthrough, future aero-engines will have higher overall pressure ratios (OPR) to increase thermal efficiency and will have higher bypass ratios (BPR) to increase propulsive efficiency. These lead to smaller and hotter high pressure cores. As core engine technologies have been addressed in the previous project, E-BREAK project will ensure the mandatory evolution of sub-systems. It is indeed required for enabling integration of engine with new core technologies to develop adequate technologies for sub-systems. E-BREAK will aim to adapt sub-systems to new constraints of temperature and pressure. The overall picture of these initiatives bring all technology bricks to a TRL level ensuring the possibility to integrate them in a new aero engines generation before 2020. In its 2020 vision, ACARE aims to reduce by 50% per passenger kilometer CO2 emissions with an engine contribution targeting a decrease by 15 to 20% of the SFC. NOX emissions would have to be reduced by 80 % and efforts need to be made on other emissions. E-BREAK will be an enabler of the future UHOPR integrated engine development, completing efforts done in previous or in on-going Level 2 programs.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: AAT.2011.1.4-2. | Award Amount: 67.80M | Year: 2011

The main objective of the LEMCOTEC project will be the improvement of core-engine thermal efficiency by increasing the overall pressure ratio (OPR) to up to 70 leading to a further reduction of CO2. Since NOx increases with OPR, combustion technologies have to be further developed, at the same time, to at least compensate for this effect. The project will attain and exceed the ACARE targets for 2020 and will be going beyond the CO2 reductions to be achieved by on-going FP6 and FP7 programmes including Clean Sky: 1.) CO2: minus 50% per passenger kilometre by 2020, with an engine contribution of 15 to 20%, 2.) NOx: minus 80% by 2020 and 3.) Reduce other emissions: soot, CO, UHC, SOx, particulates. The major technical subjects to be addressed by the project are: 1.) Innovative compressor for the ultra-high pressure ratio cycle (OPR 70) and associated thermal management technologies, 2.) Combustor-turbine interaction for higher turbine efficiency & ultra-high OPR cycles, 3.) Low NOx combustion systems for ultra-high OPR cycles, 4.) Advanced structures to enable high OPR engines & integration with heat exchangers, 5.) Reduced cooling requirements and stiffer structures for turbo-machinery efficiency, 6.) HP/IP compressor stability control. The first four subjects will enable the engine industry to extend their design space beyond the overall pressure ratio of 50, which is the practical limit in the latest engines. Rig testing is required to validate the respective designs as well as the simulation tools to be developed. The last two subjects have already been researched on the last two subjects by NEWAC. The technology developed in NEWAC (mainly component and / or breadboard validation in a laboratory environment) will be driven further in LEMCOTEC for UHPR core engines. These technologies will be validated at a higher readiness level of up to TRL 5 (component and / or breadboard validation in a relevant environment) for ultra-high OPR core-engines.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENERGY.2011.7.2-1 | Award Amount: 5.25M | Year: 2012

The growing share of electricity generation from intermittent renewable energy sources as well as increasing market-based cross border flows and related physical flows are leading to rising uncertainties in transmission network operation. In the mainland central Europe synchronous area due to large installations of renewable energy generation such as wind and photovoltaic, the difference between actual physical flows and the market exchanges can be very substantial. Remedial actions were identified by previous smart grid studies within the 6th European framework program in operational risk assessment, flow control and operational flexibility measures for this area. At the same time an efficient and sustainable electricity system requires an efficient usage of existing and future transmission capacities to provide a maximum of transportation possibilities. New interconnections and devices for load flow control will be integrated in future transmission networks and will offer new operational options. Further developments of coordinated grid security tools are one of the major challenges TSOs will face in future. The methods to be applied have to take into account all technological measures to enhance flexibility of power system operations. The zonal structure of the European energy market along with the legal responsibilities of TSOs for different system areas will continue to pose increasingly complex requirements to the system operators concerning the quality and accuracy of cooperation. The proposed UMBRELLA research and demonstration project is designed for coping with these challenging issues and boundary conditions. The toolbox to be developed will enable TSOs to ensure secure grid operation also in future electricity networks with high penetration of intermittent renewables. It enables TSOs to act in a coordinated European target system where regional strategies converge to ensure the best possible use of the European electricity infrastructure.

Agency: European Commission | Branch: FP7 | Program: CP-CSA-Infra | Phase: INFRA-2011-1.1.8. | Award Amount: 7.16M | Year: 2012

The ability to quantitatively analyze plant phenotypic traits (from single cells to plant and stand level) and their dynamic responses to the environment is an essential requirement for genetic and physiological research, and the cornerstone for enabling applications of scientific findings to bioeconomy. Whereas molecular profiling technologies allow today the generation of a large amount of data with decreasing costs largely due to automation and robotics, the understanding of the link between genotype and phenotype has progressed more slowly. Insufficient technical and conceptual capacity of the plant scientific community to probe existing genetic resources and unravel environmental effects limits faster progress in this field. The development of robust and standardized phenotyping applications depends on the availability of specialised infrastructure, technologies and protocols. Europe has become a key driver in defining innovative solutions in academic and industrial settings. However, the existing initiatives at the local or member-state level represent a fragmented research landscape with similar goals. The aim of this project is to create synergies between the leading plant phenotyping institutions in Europe as a nucleus for the development of a strong European Plant Phenotyping Network (EPPN). The project fosters the development of an effective European infrastructure including human resources, expertise and communication needed to support transnational access to user communities. Joint research activities will adapt and develop novel sensors and methods for application in plant phenotyping. Innovative phenotyping concepts integrating mechanistic, medium- and high throughput as well as field phenotyping will be developed and made available to the community. This project will strengthen Europes leading role in plant phenotyping research and application through the creation of a community of research institutes, universities, industry and SMEs.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2009.2.1 | Award Amount: 3.90M | Year: 2011

IntellAct addresses the problem of understanding and exploiting the meaning (semantics) of manipulations in terms of objects, actions and their consequences for reproducing human actions with machines. This is in particular required for the interaction between humans and robots in which the robot has to understand the human action and then to transfer it to its own embodiment. IntellAct will provide means to allow for this transfer not by copying movements of the human but by transferring the human action on a semantic level. IntellAct will demonstrate the ability to understand scene and action semantics and to execute actions with a robot in two domains. First, in a laboratory environment (exemplified by a lab in the International Space Station (ISS)) and second, in an assembly process in an industrial context.\nIntellAct consists of three building blocks: (1) Learning: Abstract, semantic descriptions of manipulations are extracted from video sequences showing a human demonstrating the manipulations; (2) Monitoring: In the second step, observed manipulations are evaluated against the learned, semantic models; (3) Execution: Based on learned, semantic models, equivalent manipulations are executed by a robot.\n\nThe analysis of low-level observation data for semantic content (Learning) and the synthesis of concrete behaviour (Execution) constitute the major scientific challenge of IntellAct.\nBased on the semantic interpretation and description and enhanced with low-level trajectory data for grounding, two major application areas are addressed by IntellAct: First, the monitoring of human manipulations for correctness (e.g., for training or in high-risk scenarios) and second, the efficient teaching of cognitive robots to perform manipulations in a wide variety of applications.\n\nTo achieve these goals, IntellAct brings together recent methods for (1) parsing scenes into spatio-temporal graphs and so-called semantic Event Chains, (2) probabilistic models of objects and their manipulation, (3) probabilistic rule learning, and (4) dynamic motion primitives for trainable and flexible descriptions of robotic motor behaviour. Its implementation employs a concurrent-engineering approach that includes virtual-reality-enhanced simulation as well as physical robots. Its goal culminates in the demonstration of a robot understanding, monitoring and reproducing human action.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: EEB-ICT-2011.6.5 | Award Amount: 5.84M | Year: 2012

Buildings are responsible for 40% of energy consumption and 36% of EU CO2 emissions, whilst the transportation sector is responsible for about 30% of the EU CO2 emissions. Achieving energy performance of neighbourhoods, including buildings, transportation systems and other supporting systems, is key to achieving the EU Climate & Energy objectives, namely a reduction of 20% of greenhouse gas emissions compared to 1990 levels by 2020 and a 20% energy savings in primary energy use by 2020. These challenging environmental targets can be met only by a mix of energy-saving and energy-efficiency measures, together with other relevant actions achieved through research and innovation. Improving the energy consumption and holistic performance of buildings and neighbourhood systems is a cost-effective way of fighting against climate change and improving energy security, while also creating new markets and new job opportunities, particularly in the building sector. COOPERATE will develop an open, scalable neighbourhood service and management platform that integrates local monitoring and control functions with a cloud based service platform for the delivery of innovative energy management, security and other services in order to progress towards energy positive neighbourhoods and achieving 2020 targets. COOPERATE will carry out a substantial validation of the concepts in two validation sites, the Bouygues Challenger campus and the CIT Bishopstown campus. In doing so, COOPERATE addresses the challenges of the call by developing management and control systems, and decision-support systems addressing the dynamics of energy supply and demand in neighbourhoods. COOPERATE will optimise the use of energy beyond the buildings, includes the integration of renewable energy sources and the connection to the electricity distribution grid, and will consider appropriate business models.

Agency: European Commission | Branch: FP7 | Program: BSG-SME | Phase: SME-1 | Award Amount: 866.40K | Year: 2009

Membrane filtration has become a key technology for many environmental and industrial applications. Yet in spite of several cleaning options at hand, fouling phenomena such as cake layer formation and pore blocking still limit its performance. The objective of this project is to overcome these limits by developing, a high frequency back-pulsing device, integrating it into membrane filtration systems and transferring the knowledge gained to new, more competitive products and services offered by the SMEs involved. The key feature of the innovative back-pulse concept is a valve-less construction providing short response times, defined pulse shape and efficient membrane cleaning at minimal back-pulse flow. Selected membranes (polymeric and ceramic) and modules (capillary and flat sheet) will be tested. The integration of pulsing device and module is essential for successful scale up. It has to take into account inertia, viscosity and elasticity effects and gets prime attention in a dynamic modelling approach. The applications to be investigated range from the treatment of liquid residues of biomass-based power generation to treatment and reuse of process fluids and wastewater, including membrane bioreactor applications. The project addresses all critical points along the value chain from membrane supply to end-use. Its outputs include insight into the hydrodynamics of high frequency back-pulsing, novel back-pulsing devices, adapted membrane/module configurations and new applications for a new technique. The consortium includes 2 RTD partners focussing on technology (VITO), modelling (RWTH) and testing (FHNW), 4 SMEs manufacturing back-pulsing devices (Pirmatech), ceramic membranes (ATECH), polymeric membranes and filtration systems (Inge, A3), 1 SME as system integrator (Waterleau), 2 SME end-users (Agroservice, Bio-Energy Maasland) and one large end-user for demonstration (WSHD).

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENV.2013.6.2-2 | Award Amount: 16.30M | Year: 2013

SOLUTIONS will deliver a conceptual framework for the evidence-based development of environmental and water policies. This will integrate innovative chemical and effect-based monitoring tools with a full set of exposure, effect and risk models and assessment options. Uniquely, SOLUTIONS taps (i) expertise of leading European scientists of major FP6/FP7 projects on chemicals in the water cycle, (ii) access to the infrastructure necessary to investigate the large basins of Danube and Rhine as well as relevant Mediterranean basins as case studies, and (iii) innovative approaches for stakeholder dialogue and support. In particular, International River Commissions, EC working groups and water works associations will be directly supported with consistent guidance for the early detection, identification, prioritization, and abatement of chemicals in the water cycle. A user-friendly tool providing access to a set of predictive models will support stakeholders to improve management decisions, benefiting from the wealth of data generated from monitoring and chemical registration. SOLUTIONS will give a specific focus on concepts and tools for the impact and risk assessment of complex mixtures of emerging pollutants, their metabolites and transformation products. Analytical and effect-based screening tools will be applied together with ecological assessment tools for the identification of toxicants and their impacts. Beyond state-of-the-art monitoring and management tools will be elaborated allowing risk identification for aquatic ecosystems and human health. The SOLUTIONS approach will provide transparent and evidence-based lists of River Basin Specific Pollutants for the case study basins and support the review of the list of WFD priority pollutants.

News Article | November 16, 2016
Site: www.marketwired.com

SARATOGA, CA--(Marketwired - November 16, 2016) - Silexica, the industry leader in multicore software design automation addressing complex, multicore platforms today announced that the next generation of the company's SLX Tool Suite is shipping now. The SLX Tool Suite has been broadly adopted to automate the distribution of code onto large, multicore platforms. Based upon customer feedback, enhancements were made to this new version, which includes the SLX Parallelizer, SLX Mapper, SLX Generator, and SLX Explorer, resulting in tremendous productivity advancements. The updated tool suite broadens the type and kinds of models, supports additional languages, as well as improves the ease-of-use and early risk analysis. Building on its capability of exposing parallelism already available in sequential languages like C, the new version of the SLX Parallelizer now adds C++ language support as well. Significant improvements in the ease-of-use of the tool allows the user to simply point to an existing project on disk automating a number of steps that otherwise had to be done manually. This now allows the user to focus their attention on evaluating the tradeoffs and speedup estimations that the tool automatically provides taking into account the number of target cores and on-chip communication of the target platform. The SLX Mapper and SLX Generator currently solve the software-mapping problem of figuring out and automating which portion of the software should run on which of the available cores. This capability is enhanced in the new version by optimizing this mapping for key system parameters like power and energy in addition to throughput and latency. Target markets like wireless base stations, edge-computing devices and autonomous driving are being constrained by available power considerations and will therefore see benefits by applying these tools in optimizing their systems to meet their power and performance budgets. "In the near future deep challenges lie in optimizing communication and automotive applications onto multicores. We have successfully integrated the SLX Tool Suite into our multicore software development flow to address these challenges," said Noriyasu Nakayama, Manager Fujitsu Advanced Technologies Ltd. As the number of cores in a system continues to rise, the bottlenecks might no longer be in the performance characteristics needed of the cores themselves but rather in the communication between the cores, for example buses, network-on-chip, etc. By modeling this communication, the new release now allows the user to gather key insights into the communication congestion on chip and improve overall system performance of their applications on their multicore platforms. This release also supports 64-bit and PowerPC modeling capabilities for broader platform support. "We have been doing research based on the SLX Tool Suite for the last four years, first via collaborations with Professor Leupers and his students at RWTH Aachen University, then with the same elite group of experts at Silexica," said Dr. Xiaotao Chen, Director, Huawei Wireless R&D USA. "The System-level profiling and optimization toolset achieved surprising improvement in both performance and power efficiency over traditional approaches, from processing units (DSP/CPU) power analysis to network-on-chip power efficiency, all the way to power-aware mapping and scheduling of heterogeneous and hierarchical architectures for our wireless baseband applications." "We believe that as Moore's Law continues to slow down, and multicores fill the demand gap for computing, the industry must work together to build on common standards and open specifications to accelerate this development. That is why we are contribution our insights and capabilities to open standards like SHIM 2.0 from the Multicore Association, and this current release will cater to these open standards," CEO Maximilian Odendahl said today. The SLX Tool Suite is available for immediate download. Please contact sales@silexica.com for an evaluation copy. Today's software applications addressing complex, advanced products such as wireless baseband processing, edge computing, autonomous driving and embedded vision are driving the demand for more and more processors leading to large multi-core architectures. However, the techniques to efficiently program the heterogeneous multi-core environment largely remains a time consuming, inefficient manual process. Building on multicore research conducted over the last ten years, Silexica began solving this problem with the SLX Tool Suite about two and a half years ago, and we are seeing rapid adoption by hardware and software system architects and designers. Today, the SLX tools SLX Mapper, SLX Generator together deliver fully automated mapping of software tasks and processes onto multicore platforms, optimized for throughput, latency, or power. They leverage native programming toolchains via a source-to-source translation approach to automatically generate architecture aware and middleware-specific C codes. The SLX Explorer guides the selection of the best target hardware by providing insights into software performance/power prediction of the target application. Conversely, the SLX Parallelizer helps customers migrate legacy C, C++ applications into the multicore world giving deep insights into parallelization possibilities based on the target platform. Silexica is the leading provider of software design automation tools addressing the increasingly complex multicore platforms required to build today's embedded vision, automotive, edge computing and wireless baseband processing products. SLX tools from Silexica help embedded software developers, system architects and semiconductor providers to differentiate multicore based products. Silexica licenses its technology to renowned electronic companies around the globe and supports its customers from local offices in Germany, U.S., Japan and China. For more on Silexica, visit www.silexica.com

« IHS: connectivity, infotainment, safety to drive growth in automotive display systems to $18.6B by 2021; > 11% CAGR | Main | Uber passes 1-billion ride mark » A team at RWTH Aachen University has identified ethyllevulinate and 2-methyltetrahydrofuran as promising alternatives to cellulosic bioethanol with respect to cost and environmental impact based on a large-scale reaction screening study. In addition, the study of 97 reactions for 23 advanced biofuel candidates found that lignin-based biofuels can be excluded from further consideration and that methane, while attractive economically, shows significant environmental impact. The paper on their work is published in the ACS journal Energy & Fuels. The ongoing discussion on the feedstock change from fossil to renewable carbon sources opens up new perspectives in terms of novel conversion processes and high performance products. Nevertheless, a potential transition from fossil- to biobased products will only be realistic, if these substances not only exhibit promising properties but can be produced economically with low environmental impact. In contrast, biochemical conversion aims at low temperature refunctionalization of native molecular constituents of lignocellulosic biomass trying to reduce the energy demand of biofuel production by preserving the synthesis power of nature. Biomass is first fractionated into its main constituents cellulose, hemicellulose, and lignin using various pretreatment techniques. The fractions are then processed to so-called platform chemicals as building blocks of a variety of biobased products. The platform chemicals can be transformed by means of multistep molecular transformation to proposed biofuel molecules by a very large number of conceivable reaction pathways which comprise possible refunctionalization steps. The resulting set of pathways needs to be evaluated according to energetic, ecological, and economic performance metrics to assess the feasibility of an associated production process. … The main contribution of this paper is a comparison of reaction pathways for a large number of proposed novel biofuel molecules, which are accessible by biochemical conversion of lignocellulosic biomass. The researchers used Reaction Network Flux Analysis (RNFA), which they developed several years ago as an optimization-based screening tool aiming at a fast evaluation of a high number of conceivable reaction pathways. The RNFA, based on methods developed in metabolic engineering, systematically identifies and subsequently analyzes and ranks a large number of alternative reaction pathways based on limited data. This optimization-based method helps to detect promising production routes as well as bottlenecks in possible pathways. The reaction network is set up as a graph of arcs and nodes representing reactions and substances, respectively. The reaction network can then be analyzed by various performance criteria such as carbon efficiency or raw material cost. Typically, candidate pathways are investigated to analyze the trade-off between total annualized cost (TAC) and environmental impact (EI). The RNFA relies on data subject to uncertainty; to improve the results, the evaluation is complemented by a sensitivity analysis (SA) which accounts for the dependency of the results on model structures and parameters employed. For the biofuel study, the team classified fuels according to their molecular structure in fuel families due to the large number of proposed molecules and candidate reaction pathways. Each fuel family was first analyzed on its own; the researchers identified the top-scorer in each group in terms of minimal environmental impact and cost. These then were subject to more detailed sensitivity analyses. Ethanol served as the baseline. Ethanol was the top-scorer out of the analyzed fuel candidates in the alcohol family. Fermentation toward butanol produces acetone, butanol, and ethanol (ABE) in a molecular ratio of 3:6:1. The catalytic conversion of furfural yields a mixture of octanol, butyltetrahydrofuran, and dioctylether. These two cases result in a rather low selectivity toward the final product rendering these reaction pathways unattractive, if a pure-component fuel is aimed at as the only product. 2-Methylfuran (2-MF) was the top-scorer of the furan family, does not only show promising process performance due to pathways starting from cellulose and hemicellulose, and has already successfully been blended in a 90,000-km road-trial 2-MTHF was selected as the top-scorer in the tetrahydrofuran family, although the performance differences between it and the other members were small. The alkane, ether, and levulinate families all show good process performance in terms of TAC and EI. 6-Pentylundecane (PUD) and ethylfurfurylether (EFE) are the top-scorers of the alkane and the ether family, respectively. The performances of the levulinates are all within a reasonable range. Ethyllevulinate (EL), the identified top-scorer, shows an even better performance than ethanol though EL is the consecutive product of ethanol. Cyclohexanol was the top-scorer of the lignin-based fuels. In this paper, three most promising fuel candidates, namely, ethanol, ethyllevulinate, and 2-MTHF, exhibiting a competitive process performance in terms of TAC and EI were identified from 23 fuel candidates and 97 reaction pathways. The subsequent OAT analysis confirmed this ranking for a moderate level of parametric uncertainty. A more comprehensive, multiparametric MC [Monte Carlo] analysis showed that a clear differentiation between candidate fuels derived from cellulosic and hemicellulosic biomass fractions was not possible due to the significant level of uncertainty. The lignin-based fuels exhibit significantly worse performance, which can be explained by the complex structure of lignin preventing an efficient production of a specific pure-component fuel being competitive to cellulosic or hemi- cellulosic-based fuels. Parametric uncertainty is crucial and may even hinder an appropriate interpretation of the results. The study shows the importance of reducing the uncertainty in the parameters arising in the investment cost calculation as well as reaction yield in future work.

News Article | November 16, 2016
Site: www.newsmaker.com.au

SARATOGA, CA--(Marketwired - Nov 16, 2016) - Silexica, the industry leader in multicore software design automation addressing complex, multicore platforms today announced that the next generation of the company's SLX Tool Suite is shipping now. The SLX Tool Suite has been broadly adopted to automate the distribution of code onto large, multicore platforms. Based upon customer feedback, enhancements were made to this new version, which includes the SLX Parallelizer, SLX Mapper, SLX Generator, and SLX Explorer, resulting in tremendous productivity advancements. The updated tool suite broadens the type and kinds of models, supports additional languages, as well as improves the ease-of-use and early risk analysis. Building on its capability of exposing parallelism already available in sequential languages like C, the new version of the SLX Parallelizer now adds C++ language support as well. Significant improvements in the ease-of-use of the tool allows the user to simply point to an existing project on disk automating a number of steps that otherwise had to be done manually. This now allows the user to focus their attention on evaluating the tradeoffs and speedup estimations that the tool automatically provides taking into account the number of target cores and on-chip communication of the target platform. The SLX Mapper and SLX Generator currently solve the software-mapping problem of figuring out and automating which portion of the software should run on which of the available cores. This capability is enhanced in the new version by optimizing this mapping for key system parameters like power and energy in addition to throughput and latency. Target markets like wireless base stations, edge-computing devices and autonomous driving are being constrained by available power considerations and will therefore see benefits by applying these tools in optimizing their systems to meet their power and performance budgets. "In the near future deep challenges lie in optimizing communication and automotive applications onto multicores. We have successfully integrated the SLX Tool Suite into our multicore software development flow to address these challenges," said Noriyasu Nakayama, Manager Fujitsu Advanced Technologies Ltd. As the number of cores in a system continues to rise, the bottlenecks might no longer be in the performance characteristics needed of the cores themselves but rather in the communication between the cores, for example buses, network-on-chip, etc. By modeling this communication, the new release now allows the user to gather key insights into the communication congestion on chip and improve overall system performance of their applications on their multicore platforms. This release also supports 64-bit and PowerPC modeling capabilities for broader platform support. "We have been doing research based on the SLX Tool Suite for the last four years, first via collaborations with Professor Leupers and his students at RWTH Aachen University, then with the same elite group of experts at Silexica," said Dr. Xiaotao Chen, Director, Huawei Wireless R&D USA. "The System-level profiling and optimization toolset achieved surprising improvement in both performance and power efficiency over traditional approaches, from processing units (DSP/CPU) power analysis to network-on-chip power efficiency, all the way to power-aware mapping and scheduling of heterogeneous and hierarchical architectures for our wireless baseband applications." "We believe that as Moore's Law continues to slow down, and multicores fill the demand gap for computing, the industry must work together to build on common standards and open specifications to accelerate this development. That is why we are contribution our insights and capabilities to open standards like SHIM 2.0 from the Multicore Association, and this current release will cater to these open standards," CEO Maximilian Odendahl said today. The SLX Tool Suite is available for immediate download. Please contact [email protected] for an evaluation copy. Today's software applications addressing complex, advanced products such as wireless baseband processing, edge computing, autonomous driving and embedded vision are driving the demand for more and more processors leading to large multi-core architectures. However, the techniques to efficiently program the heterogeneous multi-core environment largely remains a time consuming, inefficient manual process. Building on multicore research conducted over the last ten years, Silexica began solving this problem with the SLX Tool Suite about two and a half years ago, and we are seeing rapid adoption by hardware and software system architects and designers. Today, the SLX tools SLX Mapper, SLX Generator together deliver fully automated mapping of software tasks and processes onto multicore platforms, optimized for throughput, latency, or power. They leverage native programming toolchains via a source-to-source translation approach to automatically generate architecture aware and middleware-specific C codes. The SLX Explorer guides the selection of the best target hardware by providing insights into software performance/power prediction of the target application. Conversely, the SLX Parallelizer helps customers migrate legacy C, C++ applications into the multicore world giving deep insights into parallelization possibilities based on the target platform. Silexica is the leading provider of software design automation tools addressing the increasingly complex multicore platforms required to build today's embedded vision, automotive, edge computing and wireless baseband processing products. SLX tools from Silexica help embedded software developers, system architects and semiconductor providers to differentiate multicore based products. Silexica licenses its technology to renowned electronic companies around the globe and supports its customers from local offices in Germany, U.S., Japan and China. For more on Silexica, visit www.silexica.com

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENERGY.2008.6.1.4 | Award Amount: 17.19M | Year: 2009

The overall objective of this project is to provide and demonstrate technical solutions which will allow the use of state-of-the-art highly efficient, reliable gas turbines in the next generation of IGCC plants, suitable for combusting undiluted hydrogen-rich syngas derived from a pre-combustion CO2 capture process, with high fuel flexibility. The recognised challenge is to operate a stable and controllable gas turbine on hydrogen-rich syngas with emissions and process parameters similar to current state-of-the-art natural gas turbine engines. This objective will have severe implications on the combustion technology, hot gas path materials, the aerodynamic performance of turbomachinery components, and the system as a whole. The project will address these issues in Subprojects: SP1: Combustion; SP2: Materials; SP3: Turbomachinery and SP4: System analysis. In addition, the project will also look into gas turbine fuel flexibility, which will be demonstrated in order to allow the burning of back-up fuels, such as natural gas, without adversely affecting the reliability and availability. This is an important operational requirement to ensure optimum use of the gas turbine. The H2-IGCC project coordinated by the European Turbine Network - gathers the whole value chain of gas turbine power plant technology, including Original Equipment Manufacturers, GT users/operators and research institutes with diverse key expertise needed to fulfil the objectives. Successful dissemination and implementation of the results will open up the market for IGCC with Carbon Capture and Storage (CCS), as it will improve the commercial competitiveness of IGCC technology. In particular, the integrated approach used in the project will enhance confidence and significantly reduce deployment times for the new technologies and concepts developed in this project. The vision is that this will allow for the deployment of high efficiency gas turbines in competitive IGCC plants with CCS technology by 2020.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: MG-2.1-2014 | Award Amount: 18.00M | Year: 2015

IN2RAIL is to set the foundations for a resilient, consistent, cost-efficient, high capacity European network by delivering important building blocks that unlock the innovation potential that exists in SHIFT2RAIL: innovative technologies will be explored and resulting concepts embedded in a systems framework where infrastructure, information management, maintenance techniques, energy, and engineering are integrated, optimised, shared and exploited. IN2RAIL will make advances towards SHIFT2RAIL objectives: enhancing the existing capacity fulfilling user demand; increasing the reliability delivering better and consistent quality of service; reducing the LCC increasing competitiveness of the EU rail system. To achieve the above, a holistic approach covering Smart Infrastructures, Intelligent Mobility Management (I2M)and Rail Power Supply and Energy Management will be applied. Smart Infrastructure addresses the fundamental design of critical assets - switches and crossings and tracks. It will research components capable of meeting future railway demands and will utilise modern technologies in the process. Risk and condition-based LEAN approaches to optimise RAMS and LCC in asset maintenance activities will be created to tackle the root causes of degradation. I2M researches automated, interoperable and inter-connected advanced traffic management systems; scalable and upgradable systems, utilising standardised products and interfaces, enabling easy migration from legacy systems; the wealth of data and information on assets and traffic status; information management systems adding the capability of nowcasting and forecasting of critical asset statuses. Rail Power Supply and Energy Management create solutions to improve the energy performance of the railway system. Research on new power systems characterised by reduced losses and capable of balancing energy demands, along with innovative energy management systems enabling accurate and precise estimates of energy flows.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: SST.2012.1.1-3. | Award Amount: 6.95M | Year: 2012

MERLINs main aim and purpose is to investigate and demonstrate the viability of an integrated management system to achieve a more sustainable and optimised energy usage in European electric mainline railway systems. MERLIN will provide an integrated optimisation approach that includes multiple elements, dynamic forecasting supply-demand scenarios and cost considerations to support operational decisions leading to a cost-effective intelligent management of energy and resources through: Improved design of existing and new railway distribution networks and electrical systems as well as their interfaces with the public grid and considering network interconnections Better understanding of the influence on energy demand of operations and operational procedures of the different elements of the railway system Identification of technologies and solutions able to further contribute to the optimisation of energy usage More efficient traction energy supply based on optimised use of resources Understanding of the cross-dependency between these different technological solutions to define optimum combinations for optimised energy usage Improving cost effectiveness of the overall railway system Contribution to European standardisation (TecRec) MERLIN will also deliver the interface protocol and the architecture for energy management systems in the railway domain, combining the technical development with new business model that would enable and foster their application.

News Article | November 29, 2016
Site: www.eurekalert.org

Combining the power of 27 data resources, Omnipath helps researchers see biological signalling pathways with unprecedented accuracy. Developed by researchers in the UK and Germany and published in Nature Methods, OmniPath offers a comprehensive, unified collection of literature-curated signalling pathways based on an analysis of 41,000 scientific papers. All the functions happening in our cells are controlled by groups of molecules working together through signalling pathways. Once the first molecule receives a signal, the next one is activated, and so on. When things go wrong in these pathways, cancer can develop. Many cancer drugs work by putting up roadblocks in a pathway, stopping the signal and hopefully the growth of cancerous tissue. To figure out how signalling pathways work, molecular biologists carry out and validate experiments, sometimes over many years, to characterise the exact interactions taking place between proteins. Researchers can share the results of these pathway studies in public databases, to build knowledge collectively. The data are put together with the results of thousands of published studies on molecular interactions. These are organised by expert 'curators' so they are discoverable, and can help researchers shape new experiments or analyse new results. There are now over 27 public databases on signalling interactions, each of which offers something different and many of which offer custom formats. OmniPath, developed by researchers at EMBL-EBI, RWTH Aachen University and the Earlham Institute, gives a unified view of all the 'literature-curated' signalling interactions in these databases. At its launch, OmniPath has references to more than 41,000 original studies, with data representing 36,557 interactions between 7,984 proteins. The interactome, which describes all the biological interactions in an organism, could include anywhere from 100,000 to 250,000 interactions in a human. That is a huge amount of information to piece together, so accuracy and consistency are paramount. "The work of data curators is invaluable because without them the data would never come together with the kind of precision you need in biology," says Dénes Türei, EIPOD postdoctoral fellow at EMBL-EBI. "It has been exciting to work together with people from so many disciplines, and produce this concise view into the collective, current knowledge of signalling pathways." "Researchers tend to trust the accuracy of curated resources, without looking too deeply into their actual content and methods," says Tamás Korcsmáros, Fellow of the Earlham Institute and Institute of Food Research. "Benchmarking studies have mainly focused on resources with interactions from high-throughput experiments, and even these have been few and far between." The new study provides comprehensive guidelines, based on an extensive examination of more than 50 data resources, to help researchers select the most appropriate data resource for their work. The data in OmniPath are primarily based on small-scale experiments, but its Pypath software makes it possible to add datasets obtained from large screening experiments or converted from reactions. Pypath (a Python module) lets users build custom signalling networks and combine them with other data. It is a powerful tool for incorporating pathways into bioinformatics workflows and makes the analysis behind OmniPath fully open source, transparent and easily reproducible. "We compared all manner of signalling data resources and clarified the properties of different datasets, which helps researchers make better-informed decisions in their analyses," says Julio Saez-Rodriguez, visiting group leader at EMBL-EBI and professor at RWTH Aachen. "It has already proved very valuable for the research within our groups, and we hope others will find it valuable as well." 1) Tamás Korcsmáros, Fellow at the Earlham Institute and the Institute of Food Research is available for interview. For press queries at Earlham Institute, please contact: Hayley London Marcomms Officer, Earlham Institute (EI) +44 (0)1603 450107 Hayley.London@earlham.ac.uk 2) Accompanying figures from paper can be accessed, here: https:/ 3) Paper: Turei D, Korcsmaros T and Saez-Rodriguez J (2016) Omnipath: guidelines and gateway for literature-curated signaling pathway resources. Nature Methods13(12); published online 29 November 2016. DOI: 10.1038/nmeth.4077 The Earlham Institute (EI) is a world-leading research institute focusing on the development of genomics and computational biology. EI is based within the Norwich Research Park and is one of eight institutes that receive strategic funding from Biotechnology and Biological Science Research Council (BBSRC) - £6.45M in 2015/2016 - as well as support from other research funders. EI operates a National Capability to promote the application of genomics and bioinformatics to advance bioscience research and innovation. EI offers a state of the art DNA sequencing facility, unique by its operation of multiple complementary technologies for data generation. The Institute is a UK hub for innovative bioinformatics through research, analysis and interpretation of multiple, complex data sets. It hosts one of the largest computing hardware facilities dedicated to life science research in Europe. It is also actively involved in developing novel platforms to provide access to computational tools and processing capacity for multiple academic and industrial users and promoting applications of computational Bioscience. Additionally, the Institute offers a training programme through courses and workshops, and an outreach programme targeting key stakeholders, and wider public audiences through dialogue and science communication activities.http://www. / @EarlhamInst

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.2.2 | Award Amount: 3.77M | Year: 2009

Deaf communities revolve around sign languages as they are their natural means of communication. Although deaf, hard of hearing and hearing signers can communicate without boundaries amongst themselves, there is a serious challenge for the deaf community in trying to integrate into educational, social and work environments, as the vast majority of Europeans do not have signing skills. The overall goal of SignSpeaker is to develop a new vision-based technology for translating continuous sign language to text, in order to improve the communication between deaf and hearing communities. To this end, at the beginning of the project a new scientific study will be carried out to increase the linguistic understanding of sign languages; this new knowledge about the nature of sign language structure from the perspective of machine recognition of continuous sign language is crucial for a further development of sign-language-to-text technologies. The breakthrough in the understanding of sign language will allow a subsequent breakthrough in the development a new vision-based technology for continuous sign language recognition and translation to text. The SignSpeaker system will track the dominant and non-dominant hand, as well as facial expressions and body posture, taking into account the signs performed before and after or, in other words, taking into account the context in which a sign has been realised; the new technology will be also signer and ambient-independent. SignSpeaker will be the first step to approach sign language recognition and translation to the levels already obtained in similar technologies like translating from text-to-speech and speech-to-text. But the impact of SignSpeakers results is much broader than the unique application in sign languages, because the results have also important applications in the industry for improving human-machine communication by gesture and for an automatic object and body part recognition and tracking in video streams.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: SST.2008.1.1.3. | Award Amount: 2.59M | Year: 2009

Noise Reducing Devices (barriers, claddings, covers and added devices following EN14388) play an important role in noise reduction: optimizing their global performance is of major concern towards Sustainable Surface Transport. QUIESST will merge, for the very first time and within a true holistic approach, true intrinsic products characteristics, whatever their materials and shapes, together with their extrinsic ones, in order to assess their actual global capacities to reduce the amount of people exposed to noise (END target). It will address 5 main topics: NEAR / FAR FIELD RELATIONSHIP: linking the intrinsic characteristics to the corresponding extrinsic far field effect; IN-SITU MEASUREMENT METHODS: developing methods relevant of the actual intended use, allowing long term performances control; COMPARING NRDs PERFORMANCES with different test methods: building a database comparing both existing and new tests results and providing the relevant relationship; OPTIMIZING NRDs GLOBAL PERFORMANCE through a HOLISTIC APPROACH: considering acoustic, non acoustic and global impact optimization, multicriteria optimization strategies, and possible global performance indicators; SUSTAINABILITY: defining the relevant generic criteria and developing the first existing NRDs overall sustainability assessment method. The final verifiable result will be the ACTUAL USE of the Guidebook to NRD optimisation as a reference tool for noise mitigation. QUIESST addresses the call as it concerns surface transport noise abatement (road AND rail), considers cost benefit analysis and addresses the END objectives, covers true holistic noise abatement solutions through wave propagation and systems for passive compensation. Its team, made of 14 partners from 9 countries integrates the relevant stakeholders: Infrastructures, Industry, Universities, Research Institutes and SME. It addresses important environmental and economic concerns and will contribute to promote EU NRDs industry.

Agency: European Commission | Branch: H2020 | Program: SGA-RIA | Phase: FETFLAGSHIP | Award Amount: 89.00M | Year: 2016

This project is the second in the series of EC-financed parts of the Graphene Flagship. The Graphene Flagship is a 10 year research and innovation endeavour with a total project cost of 1,000,000,000 euros, funded jointly by the European Commission and member states and associated countries. The first part of the Flagship was a 30-month Collaborative Project, Coordination and Support Action (CP-CSA) under the 7th framework program (2013-2016), while this and the following parts are implemented as Core Projects under the Horizon 2020 framework. The mission of the Graphene Flagship is to take graphene and related layered materials from a state of raw potential to a point where they can revolutionise multiple industries. This will bring a new dimension to future technology a faster, thinner, stronger, flexible, and broadband revolution. Our program will put Europe firmly at the heart of the process, with a manifold return on the EU investment, both in terms of technological innovation and economic growth. To realise this vision, we have brought together a larger European consortium with about 150 partners in 23 countries. The partners represent academia, research institutes and industries, which work closely together in 15 technical work packages and five supporting work packages covering the entire value chain from materials to components and systems. As time progresses, the centre of gravity of the Flagship moves towards applications, which is reflected in the increasing importance of the higher - system - levels of the value chain. In this first core project the main focus is on components and initial system level tasks. The first core project is divided into 4 divisions, which in turn comprise 3 to 5 work packages on related topics. A fifth, external division acts as a link to the parts of the Flagship that are funded by the member states and associated countries, or by other funding sources. This creates a collaborative framework for the entire Flagship.

Agency: European Commission | Branch: FP7 | Program: NOE | Phase: ICT-2009.2.2 | Award Amount: 7.57M | Year: 2010

Linguistic diversity is a corner stone of our multicultural European society. To preserve this essential asset in the age of the emerging information and knowledge society, Europe needs ICT technologies and applications at affordable costs that\n\n enable communication, collaboration and participation across language boundaries\n secure their language users equal access to the information and knowledge society\n support each language in the advanced functionalities of networked ICT\n\nPrerequisites of these applications are advances in several fields of Human Language Technologies (HLT) such as\n\n machine translation (MT) including automatic translation and machine assisted human translation\n technologies for information and knowledge management including IR, crosslingual IR and corporate memories\n technologies for document and content production and management (including authoring tools, language checking and interactive content applications)\n technologies for intuitive interfaces to all types of technology (including multimodal user interfaces, speech interfaces for interactive mobile applications, robot control interfaces)\n\nBuilding a single EU information space reflecting and supporting the cultural diversity of our continent as an adequate foundation for the multilingual European information and knowledge society is a major challenge. Because of the complexity of human language and the number of languages to be included this challenge demands a large collective effort of research and language communities as well as several industrial sectors.\n\nT4ME shall seek progress by approaching open problems in collaboration with other research fields such as machine learning, social computing, cognitive systems, knowledge technologies and multimedia content. It shall mobilize and strengthen the European HLT community encompassing researchers, developers and language professionals through networking of research and by creating new schemes of sharing resources and efforts.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2009.6.1 | Award Amount: 21.87M | Year: 2010

The eCoMove project will create an integrated solution for road transport energy efficiency by developing systems and tools to help drivers sustainably eliminate unnecessary fuel consumption (and thus CO2 emissions), and to help road operators manage traffic in the most energy-efficient way. By applying this combination of cooperative systems using vehicle-infrastructure communication, the project aims to reduce fuel consumption by 20% overall. This target can be achieved by:\n\n Saving unnecessary kilometers driven (optimising routes)\n Helping driver to save fuel (optimising driver behaviour)\n Managing traffic more efficiently (optimising network management)\n\nThe eCoMove concept rests on the idea that, for a given trip by a particular driver in a particular vehicle, there is some least possible fuel consumption that could be achieved by the perfect eco-driver travelling through the perfectly eco-managed road network. In reality, both drivers and traffic management systems fall short of this ideal, and much fuel is wasted and CO2 emitted unnecessarily.\nThe eCoMove innovations will target the two sources of this avoidable fuel consumption: private trips and freight/logistics trips.\n\nThis integrated project (IP) will structure into six different sub-projects:\n1. Coordination and Management.\n2. Core Technology Integration both to develop common core technologies and to ensure strong technical coordination across the IP.\n3. ecoSmartdriving to develop solutions for eco-driving support for car drivers,\n4. ecoFreight & Logistices, for both eco-driving support for trucks and eco-freight and logistics management.\n5. ecoTrafficManagement & Control to develop applications for cooperative eco-traffic network management.\n6. Validation & Evaluationto validate the performance and effectiveness of all applications in a number of urban, non-urban and motorway environments.\n\nKey objectives of eCoMove innovation are to develop and validate the following applications:\n ecoSmartDriving to improve driver eco-performances, including: ecoTripPlanning, on trip dynamic green routing, ecoDriving support, ecoPostTrip and ecoMonitoring;\n ecoDriver Coaching System and in-vehicle Truck eCoNavigation for good vehicle drivers\n cooperative ecoFleet Planning and Routing for environmental sound ecoFreight & Logistics\n ecoAdaptive Balancing & Control system as well as cooperative Fuel-efficient Motorway system as means for ecoTrafficManagement & Control.\n\nThese important eCoMove innovations are enabled by the use of cooperative information exchange, such as vehicle fuel consumption data & route destination by the traffic system, the traffic lights phase data, speed and route recommendations by the vehicle.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: AAT-2007-4.4-01 | Award Amount: 65.12M | Year: 2008

Even though composite materials are more and more used in modern airframes, many significant improvements are still achievable. Firstly, the substitution of the assembly of many small composite parts by a single one-shot large part provides additional weight reduction. Secondly, the final assembly line process must be adapted to composite properties (lack of ductility, stiffness). Thirdly, if the appropriate level of confidence and cycle time was available, Simulation-based design would provide a faster and less expensive path to find the optimal structures than the current development process, which relies on physical tests. Lastly, more conductive composites are necessary to avoid additional weight for system protection. The aim of MAAXIMUS (More Affordable Aircraft structure through eXtended, Integrated, & Mature nUmerical Sizing) is to demonstrate the fast development and right-first-time validation of a highly-optimised composite airframe. The MAAXIMUS objectives related to the highly-optimised composite airframe are: 50% reduction of the assembly time of large composite sections; 10% reduction of manufacturing & assembly recurring costs; 10% reduction of the structural weight. The MAAXIMUS objective related to a faster development is to reduce by 20% the current development timeframe of aircraft structures and by 10% the corresponding cost. The MAAXIMUS objective related to the right-first-time structure is to additionally reduce the airframe development costs by 5% through the delivery of a predictive virtual test capability for large composite structures with a quantified level of confidence, to avoid late and costly changes This will be achieved through coordinated developments on a physical platform, to develop and validate the appropriate composite technologies for low weight aircraft and a virtual structure development platform, to identify faster and validate earlier the best solutions through major improvements in airframe Simulation-base design.

Agency: European Commission | Branch: H2020 | Program: IA | Phase: GV-4-2014 | Award Amount: 28.42M | Year: 2015

The ECOCHAMPS project addresses topic GV-4-2014, Hybrid Light and Heavy Duty Vehicles. The work will, in a single coordinated project, address all aspects of this topic and will be conducted by 26 partners representing the European automotive industry (OEMs (EUCAR), suppliers (CLEPA), ESPs and universities (EARPA)) including members of ERTRAC and EGVIA. The objective is to achieve efficient, compact, low weight, robust and cost effective hybrid powertrains for both passenger cars and commercial vehicles (buses, medium and heavy duty trucks) with increased functionality, improved performance, comfort, safety and emissions below Euro 6 or VI, all proven under real driving conditions. The five demonstrator vehicles, for this purpose developed to TRL 7, that use the hybrid powertrains will among other give a direct cost versus performance comparison at two system voltage levels in the light duty vehicles, and include the modular and standardized framework components in the heavy duty vehicles. Achieving these innovations affordably will strengthen technical leadership in powertrains, enable a leading position in hybrid technology and increases the competitiveness of European OEMs. The vehicles will be ready for market introduction between 2020 and 2022 and (price) competitive to the best in-class (full hybrid) vehicles on the market in 2013. More importantly, the technology devised will impact on the reduction of CO2 emissions and the improvement of air quality. The project proposes to reach a 20% powertrain efficiency improvement and a 20% powertrain weight and volume reduction, with a 10% cost premium on the base model for the demonstrator. To meet air quality targets the project will prove, via independently supervised testing, real driving emissions at least below Euro 6 or VI limits and by simulation show the potential of the passenger car technologies to reach Super Low Emission Vehicle standards.

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: ART-06-2016 | Award Amount: 3.00M | Year: 2016

Automated Road Transport (ART) is seen as one of the key technologies and major technological advancements influencing and shaping our future mobility and quality of life. The ART technology encompasses passenger cars, public transport vehicles, and urban and interurban freight transport and also extends to the road, IT and telecommunication infrastructure needed to guarantee safe and efficient operations of the vehicles. In this framework, CARTRE is accelerating development and deployment of automated road transport by increasing market and policy certainties. CARTRE supports the development of clearer and more consistent policies of EU Member States in collaboration with industry players ensuring that ART systems and services are compatible on a EU level and are deployed in a coherent way across Europe. CARTRE includes a joint stakeholders forum in order to coordinate and harmonise ART approaches at European and international level. CARTRE creates a solid knowledge base of all European activities, supports current activities and structures research outcomes by enablers and thematic areas. CARTRE involves more than 60 organisations to consolidate the current industry and policy fragmentation surrounding the development of ART.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: AAT.2011.4.4-3. | Award Amount: 50.74M | Year: 2011

The project proposal concerns the challenges posed by the physical integration of smart intelligent structural concepts. It addresses aircraft weight and operational cost reductions as well as an improvement in the flight profile specific aerodynamic performance. This concerns material concepts enabling a conformal, controlled distortion of aerodynamically important surfaces, material concepts enabling an active or passive status assessment of specific airframe areas with respect to shape and potential damages and material concepts enabling further functionalities which to date have been unrealizable. Past research has shown the economic feasibility and system maturity of aerodynamic morphing. However, few projects concerned themselves with the challenges arising from the structural integration on commercial aircraft. In particular the skin material and its bonding to the substructure is challenging. It is the aim of this project proposal to demonstrate the structural realizability of individual morphing concepts concerning the leading edge, the trailing edge and the winglet on a full-size external wing by aerodynamic and structural testing. Operational requirements on morphing surfaces necessitate the implementation of an independent, integrated shape sensing system to ensure not only an optimal control of the aerodynamic surface but also failure tolerance and robustness. Developments made for structural health monitoring will be adapted to this task. Similar systems optimized for rapid in-service damage assessment have progressed to a maturity which allows their inclusion in the next generation of aircraft. However, the time consuming application of these sensor systems has to be further improved by integration at the component manufacturing level. The additional benefit of a utilization of these adapted systems for part manufacture process and quality control shall be assessed in SARISTU. Addressing the Nanotechnology aspect of the call, benefits regarding significant damage tolerance and electrical conductivity improvements shall be realized at sub-assembly level.

News Article | December 8, 2016
Site: www.spie.org

Achieving efficient sunlight collection over an entire day is a demanding task for stationary devices. The problem becomes even more complex when the harvested photons have to be absorbed within layers limited to a few hundreds of nanometers (or less) in thickness. This optical challenge can be addressed by a light in-coupling element that operates over a broad angular and spectral range, and that is also capable of trapping the collected light to maximize photon-to-electron conversion efficiency. Solutions developed in the silicon photovoltaic (PV) industry that rely on microscale pyramidal texturization of the absorber for light trapping are not suited to systems made of thin layers. In contrast, experimental nanophotonic approaches employing, for example, planar photonic crystals and diffraction gratings or plasmonic structures have been successfully implemented within or next to the active layer of thin-film solar cells.1, 2 An alternative route consists of integrating a light-harvesting, polymer-based coating onto the planar thin-film stack that does not affect charge-collection properties and could enable fully flexible devices.3 In this context, biomimetic structures—mostly subwavelength and inspired by moth eyes—exhibit broadband omnidirectional anti-reflection (AR) but lack the light-trapping contribution.4 For this reason, we have replicated structures that decorate plant surfaces to produce a light-harvesting layer that combines all the previously mentioned attributes.5 More specifically, we have focused on rose petal epidermal cells, which are densely packed and convexly shaped, and display a height and width of few tens of microns (see Figure 1). Figure 1. Schematic illustration of the replica approach based on plant epidermal cells. Yellow arrows show light in-coupling, which is enhanced in the solar cell as a result of its bioinspired microstructured coating. KIT: Karlsruhe Institute of Technology. The structures that we have replicated improve light management in two ways. First, the high packing factor and aspect ratio (i.e., the ratio of the length of the vertical axis to the base diameter) of the cells confer excellent AR properties, regardless of the wavelength or the angle of incidence (AOI). The main light-collection effect of the conical microstructures is fully described by the principles of ray optics and originates from the ability of the reflected light to bounce back onto a neighboring epidermal cell. Shallow nanocorrugation on the surface of the epidermal cells assists the light in-coupling mechanism to a lesser extent. Second, each epidermal cell acts as a microlens that broadens the distribution of the light-propagation angle. Thus, the optical path length is enhanced in the underlying solar cell, which results in a higher photon absorption probability and device efficiency. Before testing our method in operating PV devices, we first analyzed the optical properties of replicas obtained from different plant species. We realized this step by pouring transparent polymer directly onto the biosurfaces, resulting in an exact copy of the micro/nanostructures over a few square centimeters. We determined that the aspect ratio of the epidermal cells was the essential parameter for achieving low reflection at high AOI (see Figure 2). In fact, the integrated front-side reflection could be kept as low as 7% for an AOI of 80° by using an aspect ratio of 0.6, as found in rose petals. Figure 2. (a) Reduced reflection losses on the replica-coated surface (left) compared to the uncoated one (right). (b) Measured overall (diffuse +direct) reflection spectra of a flat resist layer and of the rose structure stacked on a black absorber for a moderate (20°) and a high (80°) angle of incidence (AOI). Owing to its remarkable AR properties, we selected the rose petal replica and imprinted it into a transparent polymer layer positioned atop a substrate comprising state-of-the-art organic solar cells. The latter were based either on PTB7-Th:PC BM-type or on PDTP-DFBT:PC BM-type polymer active layers absorbing up to 800 and 900nm, respectively. Notably, we measured a relative efficiency enhancement (with respect to an unpatterned device) of up to 13% under normal incidence, which we attribute solely to the optical effects. The most important benefits were captured for high AOI (see Figure 3). Indeed, we demonstrated a short-circuit current density enhancement of 44% at AOI =80°, that is, more than 3× higher than that obtained at AOI =0°. Figure 3. (a) Diagram of a solar cell integrating the rose structure shown with the light distribution in the glass substrate (measured by confocal laser scanning microscopy). (b) Measured overall reflection spectra of the organic solar cell with the rose structure and without (‘flat resist’) for AOIs of 20°and 80°. (c) Cosine-corrected short-circuit current density plotted as a function of the AOI for the two configurations investigated. ITO: Indium tin oxide. ZnO: Zinc oxide. PTB7-Th:PC BM: Polymer blend. MoO : Molybdenum trioxide. Ag: Silver. In summary, we have shown that plant epidermal cell replicas can be used as efficient light-harvesting elements that satisfy both the spectral and angular requirements imposed by PV. As these structures can be imprinted via a one-step process in a variety of materials and subsequent to solar cell fabrication, our approach is cost-effective, versatile, and can easily be applied to any PV technology. The plant replica structures can also be exploited for improving light management in other technologies. For example, they can be applied to organic LED substrates to enhance their light-extraction efficiency. Recent reports have shown that structural disorder can strongly impact the optical properties of photonic biostructures as well as artificial and complex light-harvesting designs.6, 7 Consequently, we are now conducting a numerical analysis of the various types of disorders encountered in rose epidermal cells, which will enable us to fine-tune our plant selection criteria. R.H. and A.M. acknowledge financial support from the Karlsruhe School of Optics and Photonics. A.M., A.S., and A.C. thank the Federal Ministry of Education and Research for funding under contract 03EK3504 (Project TAURUS), and G.G. acknowledges the support of the Helmholtz Postdoctoral Program (FE.5370.0169.0008). The authors thank Martin Theuring (NEXT ENERGY – EWE Research Centre for Energy Technology), Raphael Schmager and Benjamin Fritz (Light Technology Institute, Karlsruhe Institute of Technology, KIT), Hendrik Hölscher (Institute for Microstructure Technology, KIT), and Joachim Daumann (Botanischer Garten Karlsruhe). The experiments were performed using facilities at the Light Technology Institute, the Institute for Microstructure Technology, and the Zoological Institute at KIT. Karlsruhe Institute of Technology (KIT) Ruben Hünig is pursuing his PhD at the Light Technology Institute (LTI) at KIT on light-management structures for thin-film solar cells. His work currently focuses on plant surfaces as light-harvesting elements. Adrian Mertens studied physics at KIT and is now doing his PhD at the LTI and the Material Research Centre for Energy Systems at KIT. The main focus of his work is the investigation of angle-dependent absorption in organic single and tandem solar cells as well as the impact of scattering layers on the performance of such devices. Michael Hetterich is coordinator of the Thin-Film Photovoltaics Group at the LTI and the Institute of Applied Physics at KIT. His current research activities focus on the development and investigation of novel solar cell absorber materials as well as device modeling and optimization. Uli Lemmer received a diploma degree from the RWTH Aachen University, Germany, in 1990 and his PhD from the University of Marburg, Germany, in 1995. In 2002, he was appointed a full professor and director of the LTI. Alexander Colsmann heads the Organic Photovoltaics Group at the LTI and the Material Research Centre for Energy Systems at KIT. His further research interests include solar cells for building integration, perovskite solar cells, organic LEDs, printed electronics, printable electrodes, charge carrier transport, and electrical doping of organic semiconductors. Guillaume Gomard is the group leader for the ‘Nanophotonics’ activities at the LTI. His current research encompasses the analysis of disordered photonic crystals, scattering stochastic ensembles, and hierarchical bio-inspired photonic structures and their implementation within optoelectronic devices for enhanced efficiencies. 1. C. Trompoukis, I. Abdo, R. Cariou, I. Cosme, W. Chen, O. Deparis, A. Dmitriev, et al., Photonic nanostructures for advanced light trapping in thin crystalline silicon solar cells, Phys. Status Solidi A 212, p. 140-155, 2015. doi:10.1002/pssa.201431180 4. J. W. Leem, X.-Y. Guan, M. Choi, J. S. Yu, Broadband and omnidirectional highly-transparent coverglasses coated with biomimetic moth-eye nanopatterned polymer films for solar photovoltaic system applications, Sol. Energ. Mater. Sol. Cells 134, p. 45-53, 2015. doi:10.1016/j.solmat.2014.11.025 6. R. H. Siddique, G. Gomard, H. Hölscher, The role of random nanostructures for the omnidirectional anti-reflection properties of the glasswing butterfly, Nat. Commun. 6, p. 6909, 2015. doi:10.1038/ncomms7909 7. L. C. Andreani, A. Bozzola, P. Kowalczewski, M. Liscidini, Photonic light trapping and electrical transport in thin-film silicon solar cells, Sol. Energ. Mater. Sol. Cells 135, p. 78-92, 2015. doi:10.1016/j.solmat.2014.10.012

Misiorny M.,Jülich Research Center | Misiorny M.,Adam Mickiewicz University | Hell M.,Jülich Research Center | Wegewijs M.R.,Jülich Research Center | Wegewijs M.R.,RWTH Aachen
Nature Physics | Year: 2013

Superparamagnetism of magnetic adatoms and molecules-preferential alignment of their spins along an easy axis-is a useful effect for nanoscale applications as it prevents undesired spin reversal. The underlying magnetic anisotropy barrier-a quadrupolar energy splitting-originates from spin-orbit interaction and can nowadays be probed by electronic transport measurements. Here we predict that in a much broader class of systems, quantum dots with spins larger than 1/2, superparamagnetism can arise without spin-orbit interaction: by attaching them to ferromagnets, a quadrupolar spintronic exchange field is generated locally. It is observable by means of conductance measurements and leads to enhanced spin filtering even in a state with zero average spin. Analogously to the spintronic dipolar exchange field, giving rise to a local spin torque, the effect is susceptible to electric control and increases with tunnel coupling as well as with spin polarization. © 2013 Macmillan Publishers Limited.

Rit A.,RWTH Aachen | Spaniol T.P.,RWTH Aachen | Maron L.,CNRS Laboratory of Physics and Chemistry of Nano-Objects | Okuda J.,RWTH Aachen
Angewandte Chemie - International Edition | Year: 2013

Solubility problems solved: The first examples of discrete soluble zinc dihydride adducts with NHC ligands reacted with CO2 to produce formate species and efficiently catalyzed the dehydrocoupling of silanes with methanol. These compounds were characterized both in solution and in the solid state (see picture). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Van Aerde K.I.,Jülich Research Center | Van Aerde K.I.,Royal Netherlands Academy of Arts and Science | Feldmeyer D.,Jülich Research Center | Feldmeyer D.,RWTH Aachen | Feldmeyer D.,Julich Aachen Research Alliance
Cerebral Cortex | Year: 2015

The medial prefrontal cortex (mPFC) has been implicated in cognitive and executive processes including decision making, working memory and behavioral flexibility. Cortical processing depends on the interaction between distinct neuronal cell types in different cortical layers. To better understand cortical processing in the rat mPFC, we studied the diversity of pyramidal neurons using in vitro whole-cell patch clamp recordings and biocytin staining of neurons, followed by morphological analysis. Using unsupervised cluster analysis for the objective grouping of neurons, we identified more than 10 different pyramidal subtypes spread across the different cortical layers. Layer 2 pyramidal neurons possessed a unique morphology with wide apical dendritic field spans and a narrow basal field span. Layer 3 contained the only subtype that showed a burst of action potentials upon current injection. Layer 5 pyramidal neurons showed the largest voltage sags. Finally, pyramidal neurons in layer 6 (L6) showed a great variety in their morphology with 39% of L6 neurons possessing tall apical dendrites that extend into layer 1. Future experiments on the functional role of the mPFC should take into account the great diversity of pyramidal neurons. © 2013 The Author.

Valov I.,RWTH Aachen | Valov I.,Jülich Research Center | Waser R.,RWTH Aachen
Advanced Materials | Year: 2013

Filament formation and dissolution in the system Ag(Cu)/ZrO2/Pt were observed by Liu et al. [Adv. Mater. 2012, 24, 1844]. Their explanation of the phenomena is shown here to be inappropriate. Various situations, including the "bipolar electrode" shown in the figure, are considered and the difference between the behavior in electrochemical metallization memories (ECMs) and valence change memories (VCMs) outlined. Of crucial importance for distinguishing ECM from VCM behavior, that is, the effects of cation and anion migration, is the choice of the solid materials used to transport metal cations. A possible explanation of the phenomena is proposed. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Weis S.,RWTH Aachen | Hausmann M.,Durham University
Neuroscientist | Year: 2010

Functional cerebral asymmetries (FCAs), which constitute a basic principle of human brain organization, are supposedly generated by interhemispheric inhibition of the dominant on the nondominant hemisphere. It has repeatedly been shown that FCAs are sex specific: While they are relatively stable in men, they change during the menstrual cycle in women, indicating that sex hormones might play an important role in modulating functional brain organization and brain asymmetries in particular. Modern brain imaging techniques like functional magnetic resonance imaging (fMRI) allow for the noninvasive study of the mechanisms underlying changing FCAs. Imaging data show that in women the inhibitory influence of the dominant on the nondominant hemisphere is reduced with rising levels of sex hormones in the course of the menstrual cycle. Apart from modulating interhemispheric inhibition, sex hormones also seem to change functional organization within hemispheres. These results reveal a powerful neuromodulatory action of sex hormones on the dynamics of functional brain organization in the female brain. They may further contribute to the ongoing discussion of sex differences in brain function in that they help explain the dynamic part of functional brain organization in which the female differs from the male brain. © 2010 The Author(s).

Linn E.,RWTH Aachen | Linn E.,Jülich Research Center | Rosezin R.,Jülich Research Center | Kugeler C.,Jülich Research Center | And 2 more authors.
Nature Materials | Year: 2010

On the road towards higher memory density and computer performance, a significant improvement in energy efficiency constitutes the dominant goal in future information technology. Passive crossbar arrays of memristive elements were suggested a decade ago as non-volatile random access memories (RAM) and can also be used for reconfigurable logic circuits. As such they represent an interesting alternative to the conventional von Neumann based computer chip architectures. Crossbar architectures hold the promise of a significant reduction in energy consumption because of their ultimate scaling potential and because they allow for a local fusion of logic and memory, thus avoiding energy consumption by data transfer on the chip. However, the expected paradigm change has not yet taken place because the general problem of selecting a designated cell within a passive crossbar array without interference from sneak-path currents through neighbouring cells has not yet been solved satisfactorily. Here we introduce a complementary resistive switch. It consists of two antiserial memristive elements and allows for the construction of large passive crossbar arrays by solving the sneak path problem in combination with a drastic reduction of the power consumption. © 2010 Macmillan Publishers Limited. All rights reserved.

Zander J.,KTH Royal Institute of Technology | Mahonen P.,RWTH Aachen
IEEE Communications Magazine | Year: 2013

Data rates of mobile communications have increased dramatically during the last decade. The industry predicts an exponential increase of data traffic that would correspond to a 1000-fold increase in traffic between 2010 and 2020. These figures are very similar to ones reported during the last Internet boom. In this article we assess the realism of these assumptions. We conjecture that wireless and mobile Internet access will emerge as a dominant technology. A necessary prerequisite for this development is that wireless access is abundant and becomes (almost) free. A consequence is that the projected capacity increase must be provided at the same cost and energy consumption as today. We explore technical and architectural solutions that have realistic possibility to achieve these targets. We ask if Moore's law, which has successfully predicted the tremendous advances in computing and signal processing, will also save the day for high-speed wireless access. We argue that further improvements of the PHY layer are possible, but it is unlikely that this alone provides a viable path. The exponential traffic increase has to be matched mainly by increasing the density of the access networks as well as providing a modest amount of extra spectrum. Thus, the future research challenges are in designing energy-and cost-efficient short-range architectures and systems that support super-dense deployments. A non-technical complication is that such infrastructures are likely to lead to highly fragmented markets with a large number of operators and infrastructure owners. © 1979-2012 IEEE.

Monakhov K.Y.,RWTH Aachen | Bensch W.,University of Kiel | Kogerler P.,RWTH Aachen | Kogerler P.,Jülich Research Center
Chemical Society Reviews | Year: 2015

Polyoxovanadates (POVs), known for their wide applicability and relevance in chemical, physical and biological sciences, are a subclass of polyoxometalates and usually self-assemble in aqueous-phase, pH-controlled condensation reactions. Archetypical POVs such as the robust [VIV18O42]12- polyoxoanion can be structurally, electronically and magnetically altered by heavier group 14 and 15 elements to afford Si-, Ge-, As- or Sb-decorated POV structures (heteroPOVs). These main-group semimetals introduce specific chemically engineered functionalities which cause the generally hydrophilic heteroPOV compounds to exhibit interesting reactivity towards organic molecules, late transition metal and lanthanoid ions. The fully-oxidised (VV), mixed-valent (VV/VIV and VIV/VIII), "fully-reduced" (VIV) and "highly-reduced" (VIII) heteroPOVs possess a number of intriguing properties, ranging from catalytic to molecular magnet characteristics. Herein, we review key developments in the synthetic and structural chemistry as well as the reactivity of POVs functionalised with Si-, Ge-, As- or Sb-based heterogroups. © The Royal Society of Chemistry 2015.

Zilles K.,Heinrich Heine University Düsseldorf | Zilles K.,Jülich Research Center | Amunts K.,Jülich Research Center | Amunts K.,RWTH Aachen
Science | Year: 2012

Are there unifying principles behind the structural complexity of the cerebral cortex?

Bolger A.M.,Max Planck Institute of Molecular Plant Physiology | Bolger A.M.,RWTH Aachen | Lohse M.,Max Planck Institute of Molecular Plant Physiology | Usadel B.,RWTH Aachen | Usadel B.,Jülich Research Center
Bioinformatics | Year: 2014

Motivation: Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling of paired-end data and high performance. We have developed Trimmomatic as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data. Results: The value of NGS read preprocessing is demonstrated for both reference-based and reference-free tasks. Trimmomatic is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested. Availability and implementation: Trimmomatic is licensed under GPL V3. It is cross-platform (Java 1.5+ required) and available at http://www.usadellab.org/cms/index.php?page= trimmomatic. © The Author 2014.

Beneke M.,RWTH Aachen | Falgari P.,Durham University | Schwinn C.,Durham University
Nuclear Physics B | Year: 2010

We consider the total production cross section of heavy coloured particle pairs in hadronic collisions at the production threshold. We construct a basis in colour space that diagonalizes to all orders in perturbation theory the soft function, which appears in a new factorization formula for the combined resummation of soft gluon and Coulomb gluon effects. This extends recent results on the structure of soft anomalous dimensions and allows us to determine an analytic expression for the two-loop soft anomalous dimension at threshold for all production processes of interest. © 2009 Elsevier B.V. All rights reserved.

Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: REGIONS-2007-1-01 | Award Amount: 788.42K | Year: 2008

The provinces Salzburg (AT) & North Rhine-Westfalia (GE) are collaborating at political level and through economic partnerships. BRIDGE2GEO intensifies the existing links and initiates science-business partnerships within and between the regions in order to enhance S&T-based development. The cross-cutting topic is Geographic Information. Building on earlier joint actions, technological developments & recent trends in advanced visualisation and social interaction in web2.0 will be bridged (social nets, Wikis, Second Life). Within five Strategic Networks the benefit of GI-technology will be brought to different economic sectors with affinity to selected competence priorities of the two regions. Strategies, communication & business models will be elaborated via the challenging GIS 2.0 window to promote implementation of GI-services. Special regard will be given to the European GMES initiative. Universities, research institutes and SMEs in both regions are strong players in the standardization initiatives OGC and INSPIRE. In BRIDGE2GEO the regions strengthen their structural support of RTD activities intensifying the role of RTD in EU economic development. Impacts of BRIDGE2GEO are: 1. intra-cluster (scienceindustryregional policy) 2. intra-regional (coherent research policies, development of USPs in both research and industry, complementing measures within regional structural funds) 3. transnational (structures & instruments for sustainable co-operation & improvement of market access) BRIDGE2GEO will promote synergies between regional and research policies of the two regions. Through intensive involvement of the regional development agencies RTD strategies will be integrated into the economic development strategies as a basis for more focused use of the Structural Funds for R&D activities. SMEs and research will benefit from jointly prepared relations into emerging markets. Collaboration with RTD initiatives in convergence countries will be developed.

Agency: European Commission | Branch: H2020 | Program: IA | Phase: LCE-08-2014 | Award Amount: 13.74M | Year: 2015

TILOS aims to demonstrate the optimal integration of local scale energy storage in a fully-operated, smart island microgrid that will also communicate with a main electricity grid. The main objective of the project will be the development and operation of a prototype battery storage system, based on NaNiCl2 batteries, provided with an optimum, real-environment smart grid control system and coping with the challenge of supporting multiple tasks, ranging from microgrid energy management, maximization of RES penetration and grid stability, to export of guaranteed energy amounts and provision of ancillary services to the main grid. The battery system will support both stand-alone and grid-connected operation, while proving its interoperability with the rest of microgrid components, including demand side management aspects and distributed, residential heat storage in the form of domestic hot water. At the same time, TILOS project addresses the high-priority area of the specific call concerning island regions. In doing so, apart from Tilos island, TILOS also engages the islands of Pellworm, La Graciosa and Corsica, aiming to create an island platform that will enable transfer of technological experience by making use of the smart grid system of Pellworm on the one hand, and by offering new case studies for the development of similar projects on the other. Elaboration of new case studies will be enabled by the development of an advanced microgrid simulating tool, i.e. the Extended Microgrid Simulator, offering the potential for the detailed examination of different battery technologies and microgrid configurations (stand-alone, grid connected and power market-dependent systems). Finally, by also addressing social issues, through public engagement, and by developing novel business models and policy instruments, TILOS puts emphasis on the market diffusion of the developed battery storage system and the integrated energy solution implemented on the island of Tilos.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: KBBE-2007-3-1-03 | Award Amount: 11.21M | Year: 2008

Replacing fossil oil with renewable resources is perhaps the most urgent need and the most challenging task that human society faces today. Cracking fossil hydrocarbons and building the desired chemicals with advanced organic chemistry usually requires many times more energy than is contained in the final product. Thus, using plant material in the chemical industry does not only replace the fossil material contained in the final product but also save substantial energy in the processing. Of particular interest are seed oils which show a great variation in their composition between different plant species. Many of the oil qualities found in wild species would be very attractive for the chemical industry if they could be obtained at moderate costs in bulk quantities and with a secure supply. Genetic engineering of vegetable oil qualities in high yielding oil crops could in a relatively short time frame yield such products. This project aims at developing such added value oils in dedicated industrial oil crops mainly in form of various wax esters particularly suited for lubrication. This project brings together the most prominent scientists in plant lipid biotechnology in an unprecedented world-wide effort in order to produce added value oils in industrial oil crops within the time frame of four years as well as develop a tool box of genes und understanding of lipid cellular metabolism in order for rational designing of vast array of industrial oil qualities in oil crops. Since GM technologies that will be used in the project are met with great scepticism in Europe it is crucial that ideas, expectations and results are communicated to the public and that methods, ethics, risks and risk assessment are open for debate. The keywords of our communication strategies will be openness and an understanding of public concerns.

RWTH Aachen and Jülich Research Center | Date: 2013-07-16

Disclosed is a memory element, a stack, and to a memory matrix in which the memory element can be used. Also disclosed is a method for operating the memory matrix, and to a method for determining the true value of a logic operation in an array comprising memory elements. The memory element has at least a first stable state 0 and a second stable state 1. By applying a first write voltage V_(0), this memory element can be transferred into the high-impedance state 0 and by applying a second write voltage V_(1), it can be transferred into the likewise high-impedance state 1. By applying a read voltage V_(R), the magnitude of which is smaller than the write voltages V_(0 )and V_(1), the memory element exhibits different electrical resistance values. In the parasitic current paths occurring in a memory matrix, the memory element acts as a high-impedance resistor, without in principle being limited to unipolar switching. A method has been disclosed, using an array comprising the memory elements which can be turned into a gate for arbitrary logic operations.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.1.1 | Award Amount: 19.06M | Year: 2008

Gigabit Home Access Networks are a pivotal technology to be developed if the EU Vision of the Future Internet is to be realised. Consumers will require such HANs to be simple to install, without any new wires, and easy enough to use so that information services running on the HAN will be just another utility, as, for instance, electricity, water and gas are today. The OMEGA HAN is centred round the needs of the user: gigabit RF and optical links, combined with more robust wide-area RF and visible-light communications will provide wireless connectivity within and the home and its surroundings. Combined with power-line communications this provides a home backbone without new wires. A technology-independent MAC layer will control this network and provide services as well as connectivity to any number of devices the user wishes to connect to it in any room in a house/apartment, and further, this MAC layer will allow the service to follow the user from device to device. In order to make this vision come true, substantial progress is required in the fields of optical-wireless and RF physical layers, in protocol design, and in systems architectures. For OMEGA, an interdisciplinary team from leading institutes and companies in this broad range of technologies has been assembled. OMEGA will provide a substantial consumer pull for next-generation broadband by enabling the sharing of large-date user-generated content, which will, in turn, raise the expectation for higher data rates. Also, at the same time, a push from service providers will take place, as they see the possibility of delivering new high-bandwidth services to the user throughout the home. OMEGA will present significant market opportunities for all the EU actors in the communications industry, but most importantly empower citizens by offering access to novel emotional experiences while addressing ageing, isolation, and health challenges, and thus making an important contribution to the vision of FP7.

Agency: European Commission | Branch: H2020 | Program: IA | Phase: LCE-02-2016 | Award Amount: 22.78M | Year: 2017

Five DSOs (CEZ distribuce, ERDF, EON, Enexis, Avacon) associated with power system manufacturers, electricity retailers and power system experts, propose a set of six demonstrations for 12 to 24 months. Within three years, they aim at validating the enabling role of DSOs in calling for flexibility sources according to local, time-varying merit orders. Demonstrations are designed to run 18 separate use cases involving one or several of the levers increasing the local energy system flexibility: energy storage technologies (electricity, heat, cold), demand response schemes with two coupling of networks (electricity and gas, electricity and heat/cold), the integration of grid users owning electric vehicles, and the further automation of grid operations including contributions of micro-grids. The use cases are clustered into three groups. Three use cases in Sweden and the Czech Republic address the enhancement of the distribution network flexibility itself. Five use cases in France, Germany and Sweden demonstrate the role of IT solutions to increase drastically the speed of automation of the distribution networks, which can then make the best use of either local single or aggregated flexibilities. Ten use cases in Czech Republic, France, The Netherlands and Sweden combine an increased network automation and an increased level of aggregation to validate the plausibility of local flexibility markets where both distributed generation and controllable loads can be valued. Replicability of the results is studied by the DSOs and industry with an in-depth analysis of the interchangeability and interoperability of the tested critical technology components. Dissemination targeting the European DSOs and all the stakeholders of the electricity value chain will be addressed by deployment roadmaps for the most promising use cases, thus nourishing the preparation of the practical implementation of the future electricity market design, the draft of which is expected by end of 2016.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: EINFRA-5-2015 | Award Amount: 4.05M | Year: 2015

High performance Computing is becoming a fundamental tool for the progress of science and engineering and as such for economic competitiveness. The growing complexity of parallel computers is leading to a situation where code owners and users are not aware of the detailed issues affecting the performance of their applications. The result is often an inefficient use of the infrastructures. Even when the need to get further performance and efficiency is perceived, code developers may not have sufficient insight on its detailed causes for addressing the problem properly. This may lead to blind attempts to restructure codes and consequent lack of efficiency. The objective of POP is to operate a Centre of Excellence in Computing Applications in the area of Performance Optimisation and Productivity. POP will offer the service of precisely assessing the performance of computing application of any sort, from a few hundred to many thousand processors. Also, POP will show its Customers the issues affecting the performance of their code and the most optimal way to alleviate them. POP will target code owners and users from all domains, including infrastructure operators, academic and industrial users. The estimated population of such applications in Europe is 1500 and within the project lifetime POP has the ambition of serving over 150 such codes. The Added Value of POPs services is the savings generated in the operation and use of a code, which will result in a significant Return on Investment (fixing a code costs less than running it below its optimal levels) by employing best-in-class services and release capacity for resolving other priority issues. POP will be a best-in-class centre. By bringing together the European world-class expertise in the area and combining excellent academic resources with a practical, hand-on approach, it will improve the access to computing applications, thus allowing European researchers and industry to be more competitive.

Agency: European Commission | Branch: FP7 | Program: CSA | Phase: ICT-2009.6.2 | Award Amount: 1.86M | Year: 2011

During the lifetime of the different Field Operational Tests (FOT) carried out both at National and European levels, there is a crucial need for a networking platform allowing individual FOTs to benefit from each others experiences as well as giving a better overview of the scattered activities.While FOT-Net 1 was focussing on building up the FOT network and promoting methodology, FOT-Net 2 explicitly addresses requests articulated by the FOT network which need common European positions.The prime goal of FOT-Net 2 is to increase the momentum achieved in FOT-Net 1 and further develop the strategic networking of existing and future National, European and Global FOTs e.g. US and Japan. During 36 months, the FOT Network will meet in six bi-annual FOT stakeholders meetings and three international FOT meetings.FOT-Net 2 also focuses on methodology based on recent FOT experiences. Through three targeted meetings, it will gather the relevant experts to revise and adapt in six months the FESTA methodology for FOTs on ADAS, Nomadic devices, Cooperative systems, and, in addition, address Naturalistic Driving Studies.FOT-Net 2 will create five new expert working groups in order to clarify critical topics related to the legal and ethical issues, data analysis, incident definition, impact assessment, and data sharing.The revised FESTA methodology will be promoted through six seminars supported by webinars.FOT-Net 2 will create a new web-based inventory of existing tools for data acquisition, database structure, data analysis to facilitate the setup of new FOTs.FOT-Net 2 will act as a multiplier for the dissemination and awareness of FOT activities especially in terms of inter-activities support and outreach.Finally, FOT-Net 2 will evaluate contributions of FOTs to policy goals and market deployment using an improved methodology for stakeholders analysis.The action includes all stakeholder and expert groups playing a role in existing and planned FOTs

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: MG-8.6-2016 | Award Amount: 599.94K | Year: 2016

The concept of this project is to organise two competitions for transport research awards to be announced at the TRA conference in 2018 - A Young researchers competition with the goal of stimulating the interest among young researchers/students in the field of sustainable surface transport. - A competition for senior researchers in the field of innovative surface transport concepts based on results only from EU-funded projects.

Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: SST.2008.6.0.7. | Award Amount: 300.00K | Year: 2009

This is a proposal for an early-stage research student competition a kind of Transport Research Olympics to complement the goals of the Transport Research Arena conference, TRA, in Brussels in 2010. The goal is to stimulate interest among young researchers in the conference and contribute to establishing it as the premier Transport event in the world. This activity will directly support the TRA event and reinforce its profile as a major European and internationally important conference. At the same time it will strengthen European research in surface transport by promoting collaboration and inter-disciplinarity and be recognising and rewarding excellence. The YEAR competition will be in two stages. In the first stage, up to about 600 students will submit abstracts, clearly specifying the deliverables and practical outputs of their research. There will be a network of about 80 judges, experts in surface transporation research, to encourage a wide participation from all over Europe. The abstracts will be hosted on a website which will constitute a showcase of early stage research in Europe. There will be about 6 categories, four for research which tracks, as far as possible, the core areas of the TRA conference a fifth future vision category and a sixth inter-disciplinary category which promotes the linking of pure science, socio-economics and applied science. In the second stage, about 50 finalists will be brought to the TRA-2010 conference to present their work in the form of posters and other displays. There will be gold, silver and bronze medals for each of the 6 categories and winners will be featured prominently at the conference to stimulate interest among delegates, journalists and the general public. The exhibition will be in a prominent area to encourage a wide ranging discussion between students and delegates who constitute future potential employers and stakeholders in road transport.

Agency: European Commission | Branch: FP7 | Program: JTI-CP-FCH | Phase: SP1-JTI-FCH.2010.2.4 | Award Amount: 3.06M | Year: 2012

The aim of HyTime is to deliver a bioprocess for decentral H2 production from 2nd generation biomass with a productivity of 1-10 kg H2/d. The novel strategy in HyTime is to employ thermophilic bacteria which have shown superior yields in H2 production from biomass in the previous FP6 IP HYVOLUTION. Biomass in HyTime is grass, straw, molasses or unsold organic goods from supermarkets. The biomass is fractionated and converted to H2 at high efficiency unique for thermophilic fermentation. Dedicated bioreactors and gas upgrading devices for biosystems will be constructed to increase productivity. The H2 production unit will be independent of external energy supply by applying anaerobic digestion to valorize residues. HyTime adds to the security of supply H2 from local sources and eradicates geopolitical dependence. HyTime builds on HYVOLUTION with 5 partners expanding their research efforts. Three new industrial partners, 2 of which are NEW-IG members, have joined this team with specialist expertise in 2nd generation biomass fractionation and gastechnology. This way a pan-european critical mass in agro- and biotechnological research, the energy and hydrogen sector is assembled to enforce a breakthrough in bioH2 production. The participation of prominent specialists with interdisciplinary competences from academia (1 research institute and 2 universities) and industries (3 SMEs and 2 industries) warrants high scientific quality and rapid commercialization by exploitation of project results and reinforces the European Research Area in sustainable issues. The partners in HyTime have a complementary value in being developers or stake-holders for new market outlets or starting specialist enterprises stimulating new agro-industrial activities to boost the realization of H2 from renewable resources. The concept of HyTime will facilitate the transition to a hydrogen economy by increasing public awareness of the benefits of a clean and renewable energy carrier.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2009.3.1 | Award Amount: 6.11M | Year: 2010

STEEPER addresses the development of Beyond CMOS energy-efficient steep subthreshold slope transistors based on quantum mechanical band-to-band tunnelling (tunnel FETs), with the aim of reducing the operation voltage of nanoelectronic circuits to sub-0.5V, and their power consumption by one order of magnitude.\nSTEEPER focuses on two technology tracks, united by same device principle, shared performance boosters, and compatibility with silicon CMOS. These are (i) Ultra-Thin-Body Silicon-On-Insulator technology for planar, tri-gate and nanowire tunnel FETs featuring ultra-low standby power and smartly exploiting additive boosters: high-k dielectrics, SiGe source, strain, and improved electrostatic design, and (ii) a III-V nanowire platform on silicon, as unique material to control staggered or broken bandgap boosters and devise a high performance (high-Ion, steep slope) implementation of tunnel FETs. Platform (i) will enable a hybrid platform combining high performance (HP) CMOS and low standby power (LSTP), low voltage tunnel FETs, supporting energy efficient hybrid CMOS/Tunnel-FET digital and analog/RF circuit design. In line with ITRS, STEEPER will evaluate in platform (ii) the physical and practical limits of boosting the performance of tunnel FETs with III-V nanowires on silicon, and resulting advantages for HP digital circuits.\nThe development of the two technology platforms are interactive and collaborative in terms of performance boosters, and will benefit from simulation and modelling support by the academic partners, and from investigation of the potentially critical variability and sensitivity of tunnel FETs. Industrial benchmarking is proposed at device and circuit levels by the key involved industries, and the figures of merit of hybrid CMOS/tunnel FET digital and analog circuit design will be investigated.\nThe project targets energy efficient nanoelectronic technology for high volume markets covering digital, analog/RF and mixed mode applications.

Agency: European Commission | Branch: FP7 | Program: MC-ITN | Phase: FP7-PEOPLE-ITN-2008 | Award Amount: 4.31M | Year: 2009

The MULTIMOD Training Network will have duration of 48 months and will bring together 8 academic research groups with 5 industrial partners from 8 European countries to undertake innovative research and scientific research training in Multi-Scale Computational Modeling of Chemical and Biochemical Systems. The network will provide unique cross- and multi-disciplinary training opportunities for 19 ESRs (each for 3 years) with background in chemistry, chemical engineering, physics, biology and applied mathematics. The MULTIMOD training network will address the objectives of a) equipping young researchers at the start of their careers with the knowledge and skills required for Europes knowledge-based economy and society and b) overcoming the fragmentation that exists across the European chemical/biochemical research sector. MULTIMOD will intend to raise the efficiency of the chemical/biochemical research sector and improve Europes attractiveness for researchers by (a) concentrating on advances in process modeling and simulation and (b) offering decisive training and transfer of knowledge opportunities. The operation and scope of the training network will be in accordance with the objective identified in the SusChem report Vision for 2025 and Beyond as the urgent need to train the next generation of individuals able to work across the boundaries of chemistry, biology, chemical and biochemical engineering.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENERGY.2009.7.3.3 | Award Amount: 3.76M | Year: 2010

Electric and plug-in hybrid vehicles (EV, PHEV) have the potential to contribute significantly to solving contemporary and future environmental and economic challenges of mobility. Various projects in different EU member states are currently addressing the subject in an isolated manner. The G4V consortium consisting of major European electric utilities and distinguished academic institutions are now adopting a holistic European approach to analyse the impact of a mass introduction in detail in order to optimise the grid infrastructure and make use of the inherent opportunities this represents for the operation of smart grids and energy efficiency. The objective of the project is to develop an analytical framework for the planning of technological developments in the grid infrastructure and the definition of related ICT and policy requirements in order to cope with the mass introduction of EV and PHEV. On the one hand, the aim is to clearly understand the effects of a mass introduction under physically given parameters and taking into account local aspects in different EU member states. On the other hand, the opportunities consisting in active demand and storage possibilities will be extensively explored as these also imply options for managing the possible negative impacts on the grid. The project will deliver recommendations on aspects such as possible ICT solutions, grid services anticipating, RES integration, prediction of mobile customers who are potential energy traders and the impact of dedicated tariffs. To ensure an open and holistic approach, the project will take all stakeholders into account and has established an advisory board consisting of institutions along the whole value chain. The project will generate fast and openly available results within 18 months: An analytical framework to evaluate the impact of a large scale introduction on the grid infrastructure and a visionary road map for the year 2020 and beyond.

Agency: European Commission | Branch: H2020 | Program: Shift2Rail-RIA | Phase: S2R-OC-IP5-01-2015 | Award Amount: 999.60K | Year: 2016

SMART main goal is to increase the quality of rail freight, as well as its effectiveness and capacity, through the contribution to automation of railway cargo haul at European railways. In order to achieve the main goal, SMART will deliver the following measurable objectives: complete, safe and reliable prototype solution for obstacle detection and initiation of long distance forward-looking braking, short distance wagon recognition for shunting onto buffers which can be integrated into planned Autonomous Train Operation (ATO) module, development of a real-time marshalling yard management system integrated into IT platform available at the market. The SMART prototype solution for obstacle detection will provide prototype hardware and software algorithms for obstacle detection, as well as standardised interfaces for integration into ATO module. The system will combine two night vision technologies - thermal camera and image intensifier with multi-stereo vision system and laser scanner in order to create fusion system for short (up to 20 m) and long range ( up to 1000 m) obstacle detection during day and night operation, as well as operation during impaired visibility. By this planned fusion of sensors, the system will be capable, beside reliable detection of obstacle up to 1000 m, to provide short range (< 200 m) wagon recognition for shunting operations with a \/- 5 cm distance estimation tolerance. The real-time marshalling yard management system will provide optimization of available resources and planning of marshalling operations in order to decrease overall transport time and costs associated with cargo handling. The yard management system will provide real time data about resources available over open and TAF/TSI standard data formats for connection to external network systems and shared usage of marshalling yards between different service providers.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: LCE-01-2016-2017 | Award Amount: 4.04M | Year: 2016

Storages are unavoidable components of the future smart grid with large share of variable renewable generation. However, the unit-cost of energy, that is retrieved from storages, is several times higher than the cost of energy consumed upon its output from RES. Therefore, there is a strong requirement on the optimisation of storage capacities deployed in the grid. This is especially true for the small energy sites such as DER and prosumers microgrids which are the segments, targeted by the SHAR-Q bottom-up concept. The principal objective of the SHAR-Q is to optimize the storage capacities deployed in the grid with the help of a peer-to-peer interoperability network that connects neighbourhooding RES\Storage ecosystems into a collaboration framework. Thus, the optimization of storage capacities can be achieved through their sharing among the participating actors. To get connected to the SHAR-Q network, an open interoperability gateway with semantic interface descriptors will be provided that will be based on the most adopted standards in the field. Moreover, the users will be provided with an ability to manage their contribution to the collaborative models on their own in a way that resembles the well-known social web portals (e.g. users can control with whom they wish to share specific storage capacities). The viability of the collaborative business models will be proven through added-value services, deployed over the SHAR-Q interoperability network, that will be demonstrated in 3 different pilots, targeting 3 different segments of end-users such as neighborhoods of distributed RES, coalitions of prosumers and locations with e-vehicle charging stations. The SHAR-Q research and innovation activities will be driven by the opinion of stakeholders involved in the SHAR-Q stakeholder advisory board. Their feedback will be carefully monitored throughout the project duration. Such approach is supposed to maximise the adoption potential of the SHAR-Q concept.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: NMP-2008-3.2-1 | Award Amount: 29.36M | Year: 2009

The F3 consortiums vision is that the EUs chemical industrys competitive position would be strongly enhanced if it could operate modular continuous plant (F3 plant) which combines world scale continuous plant efficiency, consistency and scalability with the versatility of batch operation. Our project will deliver such a radically new production mode based on: a) Plugandplay modular chemical production technology, capable of widespread implementation throughout the chemical industry. This technology uses generic backbone facilities designed for rapid interfacing with standardized process equipment containers (PEC). The PEC house process equipment assemblies (PEA) composed of intensified process equipment for fast, flexible future chemical production b) Holistic process design methodology applying process intensification concepts and innovative decision tools. This will accelerate process development and provides a substantial reduction in energy consumption, raw material usage and plant volumes. Our consortium of leading academic & research institutions and 7 major synthetic chemical producing industrial companies has 3 main goals: 1. To prove the technical feasibility of the F3 mode of manufacturing by building and operating a 0.1 to 30 kg/hr demonstration facility, 2. To demonstrate that operation of F3 plant will be more economical, ecoefficient and more sustainable than conventional production modes like large scale continuous or small to medium scale batch processing. 3. To drive a step change in the technology available to EU chemical production and engineering companies by designing intensified equipment for reaction and down stream processing, dissemination of standards for plug and play modular plant and providing open access to the backbone facility Our estimates indicate that the F3 concept will generate additional new business and will save 3.75 billion euro when existing products change to the F3 mode of manufacture.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: BG-07-2015 | Award Amount: 5.51M | Year: 2016

Objectives: 1) to improve the observation and predictions of oil spreading in the sea using novel on-line sensors on-board vessels, fixed structures or gliders, and smart data transfer into operational awareness systems; 2) to examine the true environmental impacts and benefits of a suite of marine oil spill response methods (mechanical collection in water and below ice, in situ burning, use of chemical dispersants, bioremediation, electro-kinetics, and combinations of these) in cold climate and ice-infested areas; 3) to assess the impacts on biota of naturally and chemically dispersed oil, in situ burning residues and non-collected oil using biomarker methods and to develop specific methods for the rapid detection of the effects of oil pollution; 4) to develop a strategic Net Environmental Benefit Analysis tool (sNEBA) for oil spill response strategy decision making. A true trans-disciplinary consortium will carry out the project. Oil sensors will be applied to novel platforms such as ferry-boxes, smart buoys, and gliders. The environmental impacts of the oil spill response methods will be assessed by performing pilot tests and field experiments in the coastal waters of Greenland, as well as laboratory tests in Svalbard and the Baltic Sea with the main focus on dispersed oil, in situ burning residues and non-collected oil. The sNEBA tool will be developed to include and overarch the biological and technical knowledge obtained in the project, as well as integrate with operational assessments being based on expertise on coastal protection and shoreline response. This can be used in establishing cross-border and trans-boundary cooperation and agreements. The proposal addresses novel observation technology and integrated response methods at extreme cold temperatures and in ice. It also addresses the environmental impacts and includes a partner from Canada. The results are vital for the off-shore industry and will enhance the business of oil spill response services.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.5.1 | Award Amount: 21.96M | Year: 2008

Each year Cardiovascular Disease (CVD) causes over 1.9 million deaths in the EU, causing direct health costs of 105 billion. Coronary Heart Disease (CHD), half of all CVD deaths, is the single most cause of death in Europe. Heart Failure (HF) a CHD being the most frequent cause of hospitalization for people over 65 has 10 million patients in the EU. Current treatment of HF entails recommendations from clinicians on medication, diet and lifestyle. Patients only receive feedback at doctors visits, or when facing symptoms. Daily monitoring, close follow up, and help on treatment routine is lacking. Non-adherence to the treatment regime is a major cause of suboptimal clinical benefit.HeartCycle will provide a closed-loop disease management solution to serve both HF and CHD patients, including hypertension, diabetes and arrhythmias as possible co-morbidities. This will be achieved by multi-parametric monitoring of vital signs, analysing the data and providing automated decision support, to derive therapy recommendations.The system will contain a patient loop interacting directly with the patient to support the daily treatment. It will show the health development, including treatment adherence and effectiveness. Being motivated, compliance will increase, and health will improve. The system will also contain a professional loop involving medical professionals, e.g. alerting to revisit the care plan. The patient loop is connected with hospital information systems, to ensure optimal and personalised care.Europes health system is undergoing radical changes due to an aging population. Its moving from reactive towards preventative care, and from hospital care to care at home. Tomorrows patients will become more empowered to take their health into their own hands. New ICT is required to enable this paradigm shift.HeartCycle, coordinated by Philips leading in electronics and health care , includes experts on textiles, ICT, decision support and user interaction.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-27-2015 | Award Amount: 3.74M | Year: 2016

In nearly every sector of industrial manufacturing surface processing techniques are used, e.g. for structuring or polishing of aesthetical or functional surfaces. In many applications laser based surface processing techniques already achieve highest precision and quality. But often the throughput is limited. State of the art for many applications in laser surface processing is the utilization of one round laser beam. The idea of ultraSURFACE is to increase the throughput for laser surface processing by at least a factor of 10 without any drawbacks in the quality of the processing results. Therefore, two different optics concepts will be realised and combined with a fast and synchronized machine, scanner and optics control. Optics Concept 1 refers to a dynamic and flexible beam-shaping approach with piezo-deformable mirrors which enables the realisation and the fast adaption of application specific intensity distributions. This will allow significant increase in feed speed and track offset and therefore of throughput. Optics Concept 2 is a beam splitting approach which allows simultaneous processing with multiple laser beams and thus a significant increase of throughput. For both concepts the implementation of prototypes is planned as well as their industrial validation in different fields of application (laser structuring, laser polishing, laser thin-film processing). The main ultraSURFACE Objectives are uSO1 Dynamic and flexible beam-shaping optics for laser surface processing uSO2 Multi-beam optics for parallel laser surface processing uSO3 Ultrafast synchronisation of optics and machine for 3D processing uSO4 Validation in industrial scenarios

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: LCE-07-2016-2017 | Award Amount: 5.00M | Year: 2016

Future energy systems will use renewable energy sources to minimise CO2 emissions. Currently large generators powered by fossil fuel turbines maintain the stability and quality of energy supplies through their inertia. The inertia of these generator-turbine groups gives providers a significant time window in which to react to network events. We urgently need to find ways to stabilise energy systems with up to 100% RES (where inertia is often lost due to power converter mediated energy transfer) to generate RE-SERVEs so that society can relax in the knowledge that it has a stable and sustainable energy supply. RE-SERVE will address this challenge by researching new energy system concepts, implemented as new system support services enabling distributed, multi-level control of the energy system using pan-European unified network connection codes. Near real-time control of the distributed energy network will be enabled by innovative 5G based ICT. Energy system use case scenarios supplied by energy providers will form the basis of energy system models. Performance characteristics of the new control mechanisms will be investigated through integration of energy simulations and live 5G communications. We will create a pan-European multi-site simulation test-bed, bringing together the best facilities in Europe. RE-SERVE results include published models of system support services, innovative architectures for the implementation of the services, performance tests on our pan-European real-time simulation, and live, test-beds, a model for pan-European unified network connection codes and actions to promote results to standardisation organisations, all of which maintain the RE-SERVE in energy systems. Commercialisation of results will result in breakthroughs in the efficient utilisation of use of RES, a spin-off and a wide range of enhanced professional solutions and services.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: LCE-23-2016 | Award Amount: 10.00M | Year: 2016

The GEMex project is a complementary effort of a European consortium with a corresponding consortium from Mexico, who submitted an equivalent proposal for cooperation. The joint effort is based on three pillars: 1 Resource assessment at two unconventional geothermal sites, for EGS development at Acoculco and for a super-hot resource near Los Humeros. This part will focus on understanding the tectonic evolution, the fracture distribution and hydrogeology of the respective region, and on predicting in-situ stresses and temperatures at depth. 2 Reservoir characterization using techniques and approaches developed at conventional geothermal sites, including novel geophysical and geological methods to be tested and refined for their application at the two project sites: passive seismic data will be used to apply ambient noise correlation methods, and to study anisotropy by coupling surface and volume waves; newly collected electromagnetic data will be used for joint inversion with the seismic data. For the interpretation of these data, high-pressure/ high-temperature laboratory experiments will be performed to derive the parameters determined on rock samples from Mexico or equivalent materials. 3 Concepts for Site Development: all existing and newly collected information will be applied to define drill paths, to recommend a design for well completion including suitable material selection, and to investigate optimum stimulation and operation procedures for safe and economic exploitation with control of undesired side effects. These steps will include appropriate measures and recommendations for public acceptance and outreach as well as for the monitoring and control of environmental impact. The consortium was formed from the EERA joint programme of geothermal energy in regular and long-time communication with the partners from Mexico. That way a close interaction of the two consortia is guaranteed and will continue beyond the duration of the project.

Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2015-ETN | Award Amount: 4.09M | Year: 2015

The ModLife project is a European Training Network initiative that brings together 5 leading European universities, 4 global industrial players and 2 SMEs to undertake research and training in the area of product-process innovation, optimization monitoring and control for life sciences and biotechnology industries. Modlife aims to develop Advanced Model-Based Optimization, Monitoring and Control as Enabling Technologies for bioprocess-product development and innovation tailored for the needs in life science industries. ModLife ETN will address excellence in research and training of next generation biochemical and process engineers in life sciences industries through: (1) Offering comprehensive training and knowledge transfer opportunities in multidisciplinary and multi-sectoral fields for training early stage researchers with multidisciplinary knowledge and competences bridging engineering and life sciences (2) Integrating and creating synergies among individually excellent but otherwise fragmented bioprocess engineering research centers across the European union in life sciences and biotechnology industries, (3) Building on advances in modeling and simulation, to develop cutting edge model-based enabling technologies and applications for optimization, monitoring and control for bioprocess and product development and innovation. The ModLife ETN aims at next generation of high performance computing tools and in-situ measurements for increasing efficiency, innovation and competitiveness of Europes life sciences and processing industries. Ultimately Modlife aims to help Europe realize the promising potential of life sciences and biotechnology- considered the next frontier technologies with profound impacts to knowledge based economy, by building the capacity to translate lab-scale life science discoveries to large scale new products and processes to match the human needs for health, nutrition and wellbeing.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: NMP-2008-3.3-1 | Award Amount: 4.56M | Year: 2009

Non-hierarchical production networks are a common environment of todays manufacturing companies. Each company is facing multiple and dynamic relationships within several networks. This complex situation causes permanent delivery delays. Delayed supplies lead to wasteful turbulences in the entire network and to expensive compensations. For the European manufacturing industry the loss of efficiency is estimated to be 1 billion Euros per year. Besides the costs the missing delivery reliability leads to poor customer satisfaction and increased lead times. The key objective of inTime is to improve delivery reliability in each customer-supplier relationship balancing production in the overall network. In order to foster delivery reliability each supply has to be rewarded according to his delivery performance. Today only a minority of supplies is successfully secured by manual negotiated delivery penalties. Due to the high variation of supplies manual levelling of incentives is a time consuming process. Therefore a fair share of risk between customer and supplier is not transparent. inTime will reach transparency by developing a market based negotiation mechanism rewarding delivery reliability at minimum transaction costs. Key innovation of the project is to establish an electronic market for trading reliability incentives. Besides the development of the market mechanism, the integration into the entire order process requires several novelties which have to be developed simultaneously: - The negotiation mechanism supports a new kind of order prioritisation. To realise this potential new planning and sequencing algorithms are needed. - In order to gain transparency on the criticality of each supply, functions analysing the internal risk and related costs of the required parts have to be developed. - Enabler for inTime is an automated order data communication. To avoid redundant developments inTime will apply the existing communication platform myOpenFactory.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.4.2 | Award Amount: 3.70M | Year: 2008

Public administrations represent the largest information bound professional communities: among them the judicial sector is one of the largest, where the needs of cooperation are critical creating an exceedingly large improvement potential through adoption of novel content management techniques and development of new solutions for its specific needs of retrieval and semantic analysis. This potential is even larger considering the growing trans-national cooperation also among several national law systems, highlight the need to adapt the technological profiles of new member states. In this context JUMAS is the leverage able to converge to an actionable knowledge starting from the content revolution. In particular, JUMAS envisages a system for the embedded semantic extraction from multimedia data that join into an advanced knowledge management system. Moreover JUMAS is tailored at managing situations in which multiple cameras and audio-source are used to record assemblies in which people debates and event sequences need to semantically reconstructed for future consultation. The project has several objectives:\n1.\tKnowledge Models and Spaces: Search directly in the audio and video source without a verbatim transcription of the proceedings.\n2.\tKnowledge and Content Management: Exploit hidden semantics in audiovisual digital libraries in order to facilitate search and retrieval, intelligent processing and effective presentation of multimedia information.\n3.\tSensor and Multimedia Integration: Information fusion deriving from multimodal sources in order to improve accuracy in automatic transcription and annotation phases.\n4.\tEffective Information Management: Streamline and Optimize the document workflow allowing the analysis of (un)structured information for document search and evidence base assessment.\n5.\tICT Infrastructure: Service Oriented Architecture supporting a large scale audio/video retrieval system focusing on scalability, interoperability and modularity.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: NMP.2011.2.2-2 | Award Amount: 4.09M | Year: 2012

Lung cancer is the most common cancer in terms of both incidence and mortality, worldwide. With a median age at diagnosis of 71, lung cancer is mainly affecting the aging population. Airway stenosis is a key problem with significant morbidity and premature death. Endobronchial stenting is a proven therapy to keep the airways open. Nevertheless the currently used clinical stents have major disadvantages either by rapid re-occlusion due to tumour ingrowths (metal stents) or massive mucus retention due to the interrupted mucociliary function (coated stents). The aim of the project is to develop a viable endobronchial stent (syn. PulmoStent) for the treatment of broncho-tracheal cancer diseases. The concept is based on the combination of stent technologies with the principles of tissue engineering. The PulmoStent is a multi-layered structure providing (1) a functional respiratory epithelium on the luminal side, which allows the maintenance of the mucociliary function in the stented area, (2) an embedded micro- or nanosphere formulations, enabling the sustained, local release of tumour-specific therapeutics in combination with (3) a mechanical separating layer on the external side, enabling a local tumour suppression to avoid stent displacement and restenosis by a growing tumour. The PulmoStent is a step change beyond the state-of-the-art from a passive to a viable and functional active implant tailored to the patient. It focuses on a clearly identified clinical need for the treatment of lung cancer. The combination of different kinds of biomaterials to a co-scaffold system for the bio-functionalization of the stent will lead to an improved performance of endobronchial stents and thereby to longer durability. The novel PulmoStent will improve the quality of life and increase the life expectancy of lung cancer patients, because of the reduced mucus retention in the stented area, and herewith the reduced risk of life-threatening pneumonia and the local tumour suppression.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: GC.SST.2012.1-4. | Award Amount: 3.11M | Year: 2012

In the next 20 years the number of small and light-weight full electric vehicles will substantially increase especially in urban areas. These Small Electric Vehicles (SEVs) shows distinctive design differences compared to the traditional car (e.g. no bonnets, vertical windscreens, outstanding wheels). Thus the consequences of impacts of SEVs with vulnerable road users (VRU) and other (heavier) vehicles will be different from traditional collisions. These fundamental changes are not adequately addressed by current vehicle safety evaluation methods and regulations. VRU protection, compatibility with heavier opponents and the introduction of active safety systems have to be appropriately taken into account in order to avoid any SEV over-engineering (e.g. heavy or complex vehicle body) by applying current regulations and substantially impair the SEVs (environmental) efficiency. Therefore the project SafeEV aims based on future accident scenarios to define advanced test scenarios and evaluation criteria for VRU, occupant safety and compatibility of SEVs. Moreover, industrial applicable methods for virtual testing of these scenarios and criteria (e.g. a method for active occupant safety assessment) will be developed. These methods are applied in order to derive protection systems for enhanced VRU and occupant safety for SEVs. The evaluation of one developed hardware system will be used to demonstrate the potential and applicability of these new methods. Dedicated best practice guidelines for VRU and occupant safety evaluation of SEVs will ensure a sustainable impact for industry and regulative organisations beyond the project duration. With the new evaluation methods developed, vehicle safety for SEV on urban roads in the next decade will be adequately addressed resulting in less fatalities and injuries without compromising vehicle efficiency. Moreover cost-efficient development of SEVs will be made possible by the new virtual testing methodologies developed.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: GC.SST.2012.1-1.;GC.NMP.2012-2 | Award Amount: 10.47M | Year: 2012

Lightweight materials such as carbon-fibre reinforced plastics have been used up to now mostly in high-performance cars with relatively high cost & low production volumes. Instead the electric cars of the future require lightweight solutions that not only enable specific design requirements to be respected but are also cost effective and sustainable throughout their lifecycle. ENLIGHT aims to accelerate the technological development of a portfolio of innovative thermoset, thermoplastic, bio-based and hybrid materials which together offer a strong potential to reduce weight and overall carbon footprint to enable their viable application to medium-high volume EVs in 2020-25. Through the collaboration of EUCAR, CLEPA and EARPA, ENLIGHT will act as an open innovation platform, integrating valuable insights from other EU research projects with a holistic design approach. Five demonstrator modules of a future EV architecture will be developed, validating the performance of the materials in structurally demanding parts of the car. The demonstration and evaluation of the lightweight potential will be supported virtually with a full vehicle model.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: MG-1.1-2014 | Award Amount: 8.97M | Year: 2015

AGILE targets multidisciplinary optimization using distributed analysis frameworks. The involvement of many disciplinary analyses ranging up to high levels of fidelity and agile workflow management are considered to be state-of-the-art and starting point for AGILE. Advanced optimization techniques and strategies will be developed in order to exploit available computing systems and to gain faster convergence to optimal solutions. Surrogates, decomposition, robust design and uncertainties, global-local optimization, mixed fidelity optimization and system-of-system optimization are central fields of research. Operating the coupled numerical system and interpreting the high fidelity results requires collaboration of heterogeneous specialists. Techniques for collaboration are the second scientific objective of AGILE using the research on optimization techniques as use case. The interactions between humans and the interactions of the design team with the numerical system both are investigated. Knowledge-enabled information technologies will be developed in order to support the collaboration process constituting the third, outer-most layer of the nested research concept. Novel technologies are iteratively implemented, tested and enhanced. Use cases are realistic overall aircraft design tasks for conventional, strut-braced, box-wing and BWB configurations. The project is set up to proof a speed up of 40% for solving realistic MDO problems compared to todays state-of-the-art. The resulting technologies will be made available; amongst others via an Open MDO Test Suite. Reduced development costs and reduced time to market will enable a more agile way of collaboration and joint development and experimenting on innovative products. AGILE pronounces the collaboration of SME, RES and HES in order to contribute to IND-centred virtual extended enterprises. AGILE considers all pre-existing conventions and will contribute to the CRESCENDO results and dissemination plan.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: SST-2007-2.1-01 | Award Amount: 4.37M | Year: 2008

Faced with a trend towards increasing freight transport, a global market that is constantly growing and the need for a resource-saving transport system, it is mandatory that European transport policy shifts the balance between all transport systems.`Intelligent MegaSwapBoxes for Advanced Intermodal Freight Transport (TelliBox) as an all-purpose loading unit will actively promote the EUs objectives of achieving intermodal integration and operational optimisation. By drawing together the ideas and contributions of freight forwarders, manufacturers and scientists, the scientific aim is to achieve an all-purpose, intermodal loading unit that is applicable to transport via road, rail, short sea and inland shipping. The advantages of containers and semitrailers will be combined by a MegaSwapBox. Challenges facing the development are that the MegaSwapBox has to - be trimodal, - be stackable and applicable for handling from the top, - use existing low floor wagons for rail transport, - provide an adaptable chassis for road transport, - have an optimised cargo volume of 100m with an internal height of 3m, - have loading facilities from three sides (completely openable doors), - offer improved safety features against pilferage. Within six decisive project steps, an interdisciplinary European consortium will realise three optimised and certified prototypes which will be tested on an intermodal European corridor (PL-D-NL-UK). TelliBox will achieve its objectives by combining new materials with innovative and intelligent constructions. A complementary bundle of scientific evaluation methods and profitability calculations will reduce project risk, and the integration of all interest groups will ensure that the MegaSwapBox is accepted. The project TelliBox seeks to successfully introduce the MegaSwapBox onto the market with a view to encouraging the standardisation of new loading units in the long run.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SPIRE-01-2014 | Award Amount: 6.00M | Year: 2015

In many aspects batch processes are superior to continuous. Therefore it is worthwhile to take advantage of recent progress in sensor technologies, modelling and automation to develop a new paradigm for the design and conduction of batch processes: a) operation at maximum efficiency, b) dynamic, quality driven process trajectories rather than fixed schedules c) detailed analysis and tracking of all relevant process and product parameter. The main objective of the proposed project is the maximization of efficiency (reg. quality, energy, raw materials, and costs) of batch processes. Integrated process control is essential for an efficient operation of industrial batch processes: it tracks the evolution of product properties, detects deviations from the target values for product quality and derives corrective actions at a stage when an automatic compensation of deviations from an optimal trajectory is still possible. This contributes to optimal energy and raw material utilisation, shortens production time and enhanced the product quality. With the ambition to deliver solutions with relevance to all sectors of the process industries, the RECOBA consortium represents a selection of batch processes operating industries and partners across the value chain of batch process control, among them 3 global players from the polymer industry (BASF), the steel industry (TKSE), and the silicon metal industry (ELKEM). Within RECOBA there will be developed and validated: (1) new & innovative solutions for the measurement of different types of quality aspects, (2) new models to realise integrated process control of batch processes & suitable online parameter adaptation technologies to keep these models valid, (3) control modules to realise concepts for real-time, model based & closed loop process control, which are easily adaptable to existing batch processes in various industrial sectors, (4) business models to approach relevant industrial sectors for a future market entry.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: NMP-2009-3.2-2 | Award Amount: 5.14M | Year: 2010

Wind turbines and aeronautic are sectors where Europe is leading the world class competition. To guarantee this competitiveness, their productivity has to be improved. The adoption of an automation strategy is a key factor to increase productivity. In the wind turbine manufacturing, the assembly is one of the core processes. Most of these assembly operations are manual which has the quality of being the most flexible way to do the work. The main objective for COSMOS is the design/development/implementation of a control system for factory management with a flexible, modular and evolvable automation approach which will permit to increase the assembly factory productivity by 20% without losing flexibility, focused on wind turbine assembly process although the solution will be suitable for other sectors. Cost models will be defined to assist in establishing the economically optimum factorys configuration and automation level. The achievement of the main objective will be obtained by fulfilling the following technical objectives: -Create a factory organisation conception based on intelligent factory units for facilitating the self-adaptation to production changes under a flexible and modular automation configuration basis. -Develop the distributed control system architecture according to such factory organisation. -Develop the service layer infrastructure between control system and equipment involved in production. COSMOS system features: -Autonomous behaviour of the factory units. -Multilayer decentralised control. The control will work in three interconnected levels. -Interoperable connectivity with factory units equipment/devices. -Local intelligence (self-adaptation to different parts conditions without human intervention). -Collaboration among equipment/devices to complete specific tasks. COSMOS will be implemented as a pilot installation for the assembly of wind turbines nacelles (most critical and added value part).

Agency: European Commission | Branch: FP7 | Program: CSA | Phase: ICT-2013.6.5 | Award Amount: 1.77M | Year: 2014

FOT-Net Data is a Support Action for international co-operation that targets efficient sharing and re-use of global data sets. It continues European and international networking activities in the domain of Field Operational Tests (FOT).During the lifetime of the different FOTs carried out both at national and European levels, there is a crucial need for a networking platform allowing individual FOTs to benefit from each others experiences as well as giving a better overview of the scattered activities.While FOT-Net 1&2 were focusing on setting up the FOT network and maintaining the FOT methodology, FOT-Net Data explicitly addresses the need to exploit the collected data. The prime goal of FOT-Net Data is to maintain and increase the momentum achieved in FOT-Net and develop the strategy for sharing and exploiting collected FOT data in National, European and international FOTs (e.g. US and Japan). FOT-Net Data develops and promotes a framework for sharing data. It takes into account the pre-requisites necessary in the FOTs, such as legal agreements, to enable future re-use of collected data. More importantly, it addresses the actual data sharing and the procedures, templates and services needed for successful research on data gathered in earlier projects. It builds a detailed catalogue of available data, enabling organizations to easily assess the value of different data sets for their research purposes.FOT-Net Data will act as a multiplier for the dissemination and awareness of FOT activities especially in terms of inter-activities support and outreach. During 36 months, the FOT Network will meet in 4 FOT data sharing workshops, 5 webinars, one FESTA revision workshop, 3 European concertation meetings and 3 international FOT meetings. The action includes stakeholder and expert groups playing a key data management role in previous and ongoing FOTs.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: FoF.NMP.2013-8 | Award Amount: 6.21M | Year: 2013

The current maintenance policies, including e.g. RCM (Reliability Centred Maintenance) and TPM (Total Productive Maintenance), can be generally useful in answering questions such as how much maintenance should be done on this machine? How frequently should this part be replaced? How many spare parts should be kept in stock? How should the shutdown be scheduled? It is generally accepted that the vast majority of maintenance models are aimed at answering efficiency questions, i.e. questions of the form How can this particular machine be operated more efficiently? and NOT effectiveness questions (the top 5 ones!), like: Q1: How can reliability, repair and EOL be included in a robust and integrated Life Cycle Cost (LCC) and Life Cycle Assessment (LCA) model of the factory (to be used for decision making along factory life cycle)? Q2: Which are the most cost-effective and optimal Repair strategies we should tailor for sets of components/machines of the factory? Q3: Which machine and/or components should we improve and how can we reduce repair time and cost? Q4: Which are the most environmental-effective EOL strategies we should tailor for sets of components/machines of the factory? Q5: How can we assess the remaining life of Re-usable components and which are most valuable Renovation technologies for the machine tools? the EASE-R3 project aims at developing a novel Integrated framework for a cost-effective and easy Repair, Renovation and Re-use of machine tools within modern Factory (machining shop floor), oriented both to SME and large OEM/end-users, and covering the entire life cycle of the system (from design stage throughout operative life).

Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: Fission-2011-2.3.1 | Award Amount: 1.29M | Year: 2012

The European Sustainable Nuclear Industrial Initiative was launched in November 2010 to anticipate the development a fleet of fast reactors with closed cycle. Three fast neutron technologies have been selected: the Sodium cooled Fast Reactor with the ASTRID prototype the Lead cooled Fast Reactor with the ALFRED demonstrator which will be preceded by a pilot plan MYRRHA the Gas cooled Fast Reactor with the ALLEGRO demonstrator With the objective of future assessment of these advanced reactor concepts, the SARGEN_IV Project is intended to gather safety experts from recognized European Technical Safety Organizations from Designers and Vendors as well as from Research Institutes and Universities to: - develop and provide a tentative commonly agreed methodology for the safety assessment, - identify open issues in the safety area, mainly addressing and focussing on assessment relevant ones, - detect and underline new fields for R&D in the safety area - provide a roadmap and preliminary deployment plan for safety-related R&D, including cost estimation. Firstly, the proposed methodology requires the identification and the ranking of the main safety issues related to these reactors which needs a strong collaboration with other European projects as CP-ESFR, GoFastR, LEADER and CDT.. Secondly, a review of the safety methodologies proposed by international organizations and those issued from national practices and European consortia in order to define the tentative commonly agreed methodology which will be therefore applied to specific safety issues relevant for the selected reactors. The project beneficiaries are convinced that fostering to harmonization of the various European safety approaches will be very beneficial and will streamlining EURATOM contribution to Generation IV International Forum in the safety field. It will also improve relations between safety assessment and research programmes efficiency in the development of new concepts.

Agency: European Commission | Branch: FP7 | Program: CP-TP | Phase: NMP-2007-3.1-2 | Award Amount: 4.74M | Year: 2008

SERVIVE net proposes the enlargement of the assortment of customizable clothing items currently on offer, the enhancement of all co-design aspects (functionality and fun) and the development and testing of a new production model based on decentralized networked SME cells.The Servive net will not only seamlessly link critical Mass-Customisation (MC) enabling services, but more important it will adapt these services to the specific needs and preferences of well-defined target customer groups. It will also enable all necessary interactions of customers with value-chain actors in transparent ways, thus enabling and encouraging the active participation of end consumers in the configuration of the customised items. The selected product configuration will in turn influence the production scenario (see the extended Micro-Factory concept below). Central to this scenario is the concept of Virtual Customer Advisor (VCA), which, depending on the profile of the customer will recommend the optimum product configuration, based either on style preferences (Style Advisor), functional requirements (e.g. for protective clothing/ sportswear) or body morphology and physical disability or problem figure related issues. On the upstream part of the chain, the Servive net will introduce the innovative organisational concept of the Networked Micro-Factory, directly linked to the concept of User-centred Production Configuration. The MF concept promotes the idea of decentralized production close to retailers and consumers (proximity advantage). MFs can range from networked small size but high-tech MC production sites, to sites equipped with automatic knitting machines, or even semi-automatic 3D assembly centres (single-ply cutter \ sewing robots). Knowledge-based web services will relate to style expertise, human body expertise and data, material and specific manufacturing knowledge.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: NMP.2011.3.2-1 | Award Amount: 5.58M | Year: 2012

In response to world-wide changes in the chemical/biopharmaceutical industry, new market requirements for specific end-use product properties as well as to stricter energy, safety and environmental constraints a revolutionary approach is needed regarding equipment design, plant operation and new production paradigms that will result in better products and processes. Process intensification (PI) is the key technological pathway to drastically improve the sustainability of the chemical and biopharmaceutical processes by replacing the existing, inefficient plant equipment with new, intensified operations. PI comprises the development of novel equipment and production methods that can bring dramatic improvements in manufacturing and processing and lead to safer, cleaner, smaller and cheaper production routes. PI is expected to open up the way for the production of new products, unblock the potential for plant operation under less stable conditions and reform entire business models to foster just-in-time or distributed production. In a series of recent publications and roadmaps, PI has been identified as the path for sustainable development. The OPTICO project aims at overcoming the present limitations on implementing PI by establishing a new methodological design approach for sustainable, intensified chemical/biopharmaceutical plant design and operation through a flexible, integrated multi-scale modeling framework coupled with advanced process analytics tools and modern optimization/control techniques. It is envisaged that, within a 3 year time frame, the proposed work will enable the innovative process design and promote a substantial improvement in chemical/biopharmaceutical plant efficiency by reducing energy consumption, operating costs, handled volumes and generated wastes as well as by improving the process efficiency and safety.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.9.9 | Award Amount: 5.94M | Year: 2013

The ScaleQIT vision is to develop a conceptual platform for potentially disruptive technologies, advance their scope and breadth and speed up the process of bringing them from the lab to the real world. ScaleQIT will address the engineering side of quantum information processing (QIP), analyzing and implementing realistic scenarios for scaling-up superconducting hybrid systems for quantum computing and quantum simulation. The work will be based on proven, well-functioning circuits and components that show great promise for integration into useful QIP systems. ScaleQIT will develop a quantum processor based on microwave resonators and waveguides coupling a small (5-10) number of superconducting qubits of the transmon type. It will achieve most of the functionalities required by DiVincenzos criteria, and will meet many of the challenges defined by the European Quantum Information and Processing Roadmap. For the development of a useful scalable platform, the ScaleQIT project will address a wide range of challenging issues, and take them far beyond the state of the art for multi-qubit platforms, addressing several central issues: feed-back and feed-forward control; error correction; quantum memory; quantum interfaces; algorithms and protocols for computing and simulation; design of scalable architectures for high performance quantum computing.ScaleQIT aims for groundbreaking applications to quantum simulation of physical systems. If successful, it may already in the short term have a disruptive effect on the development of quantum information science. In the longer term, it can be expected to have a disruptive effect on the science of computation: combining functional processor units with, say, 10 qubits, into larger distributed systems will eventually have simulation power that rivals that of powerful digital computers. By really building and testing larger quantum-engineering systems, ScaleQIT will be a path-finder on the road to developing solid-state fault-tolerant quantum architectures.

Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: AAT.2013.7-7. | Award Amount: 534.35K | Year: 2013

As mentioned in the Executive Summary of the Strategic Research & Innovation Agenda, Aviation has an important role to play in reducing greenhouse gas emissions as well as noise and local air quality issues. The continuous increase of air passenger transport generates an increasing use of hydrocarbon fuel with excessive emission of CO2 and NOX (greenhouse gases, pollutants and noise). It is well known that commercial aircraft operations impact the atmosphere by the emissions of greenhouse gases and greenhouse gas precursors, and also through the formation of contrails and cirrus clouds. In 2011, during the Aerodays in Madrid, the EC launched the future of Aeronautics in the ACARE Flight Path 2050 Vision for the Aircraft report containing the ambitious goals on the environmental impact with 90% reduction in NOx emissions, 75% reduction in CO2 emissions per passenger kilometer, and the reduction of the noise in by 65%, all relative to year 2000. To achieve the ACARE Strategic Research & Innovation Agenda green aeronautics technologies will play a more and more dominant role in mastering the challenge on Protecting the environment and the energy supply. GRAIN2 Supported Action, based on the same collaborative and win-win spirit introduced in former EU-China GRAIN project, will provide inputs and roadmaps for the development of large scale simulation strategies for greener technologies to meet the above future requirements on emissions, fuel consumption and noise. To reach these targets, green technologies efforts will have to be collected and prospected in three major lines: Air vehicle, Air Transport System and Sustainable Energies. Three folds to be investigated as future greening technologies: 1) Greening the aircraft and the aero engine 2) Greening the operational environment 3) Reducing the carbon foot print of aviation via sustainable alternative fuels

Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: Fission-2012-2.3.2 | Award Amount: 1.40M | Year: 2012

The ALLIANCE project focuses on the preparatory phase for developing the ALLEGRO demonstrator. This is based on the Gas Fast Reactor (GFR) concept, one of the 2 alternative systems under the SET-Plans European Sustainable Nuclear Industrial Initiative (ESNII), expected to be built in Central Europe. ALLIANCE covers a number of preliminary studies on fuel management, R&D roadmap & infrastructures needs, and siting, as well as the licensing roadmap, preliminary design and safety analysis. ALLIANCE will integrate experience and knowledge gained from the past or ongoing related initiatives. Arguments on why GFR technology could be accepted in Europe as a complementary option of SFR will be clearly stated. Furthermore map and highlight of national or regional initiatives supporting the development of this technology and list of countries interested in the hosting of the ALLEGRO demonstrator on its territory. The conditions for the site selection should be defined within this project. In addition the project specification on licensing and construction period will be suggested. For the R&D activities as well as for the operational and decommissioning phases specifications should be elaborated. These specifications would cover the licensing roadmap, financing and project organisation setup. According to the latest concept, a common Centre of Excellence will be created in Central Europe for GFR studies. The creation of the Centre will be the first step towards integration of fuel and reactor safety research in the region.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2009.1.1 | Award Amount: 5.05M | Year: 2010

The need for the radio spectrum for the rapidly growing broadband access services is evident. Abundant and fast access to spectrum has three main advantages: it fosters rapid innovation in wireless systems and services lowering entry barrier on the market; it enables affordable mobile broadband access to all; and makes new energy efficient wireless systems possible. Secondary use of already licensed, but poorly inefficiently used spectrum, (Cognitive Radio )has been proposed as a solution to make more efficient use of the spectrum. Low spectrum occupancy in a number of measurement campaigns worldwide has been the basis for claims of large gains in spectrum efficiency by cognitive radio. However, little research has been done to substantiate these claims. The QUASAR project aims at bridging this gap between the claims made in conventional cognitive radio research and practical implementation by assessing and quantifying the real-world benefits of secondary (opportunistic) access to primary (licensed) spectrum. The analysis is based on two key features of cognitive radio: the ability of the secondary users to discover the opportunity to use the spectrum, and assessing the electromagnetic impact of secondary user transmissions on primary system (receivers). Novel approaches are taken as we go beyond the conventional notion of detecting spectrum holes into treating spectrum opportunity discovery as a data fusion problem, as well as new schemes that cope interference from multiple uncoordinated secondary users. QUASAR will provide a comprehensive analysis of the techno-economical environment and provide detailed roadmaps and guidelines on how to apply and analyze new opportunistic spectrum access business models. The project will finally provide specific and reasoned proposals to go beyond the current regulatory framework. A balanced project team will provide results of high scientific quality and strong impact on the regulatory process and wireless business.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: Fission-2010-2.3.1 | Award Amount: 10.12M | Year: 2011

In line with the Sustainable Nuclear Energy Technology Platform (SNETP) Strategic Research Agenda (SRA) and Deployment Strategy (DS), the ARCHER project will extend the state-of-the-art European (V)HTR technology basis with generic technical effort in support of nuclear cogeneration demonstration. The partner consortium consists of representatives of conventional and nuclear industry, utilities, Technical Support Organisations, R&D institutes and universities. They jointly propose generic efforts composed of: -System integration assessment of a nuclear cogeneration unit coupled to industrial processes -Critical safety aspects of the primary and coupled system: oPressure boundary integrity oDust oIn-core hot spots oWater and air ingress accident evaluation -Essential HTR fuel and fuel back end R&D oPIE for fuel performance code improvement and validation oBack end research focused on radiolysis -Coupling component development: oIntermediate heat exchanger development oSteam generator assessment -High temperature material R&D: oCompletion of graphite design curves oMaking use of the experience of state of the art metal in conventional industry -Nuclear cogeneration knowledge management, training and communication The activities proposed are imbedded in the international framework via GIF; direct collaboration within the project with international partners from the US, China, Japan, and the republic of Korea; and cooperation with IAEA and ISTC. The proposal is a technical building block supporting nuclear cogeneration as fossil fuel alternative for industry and as such supports a high potential contribution to European energy strategy as defined in the SET-Plan. The results of the proposal will be reported to SNETP, to support the strategic pillar of other uses of nuclear energy, and the establishment of a Nuclear Cogeneration Industrial Initiative, which shall include effective (international) nuclear cogeneration demonstration.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENERGY.2013.5.1.2 | Award Amount: 8.19M | Year: 2013

Major sources for human made CO2 emissions comprise the energy and the industrial sector including cement production. One of the most appropriate concepts to capture CO2 from such point sources is the oxyfuel combustion. The main energy demand for this method results from the O2 generation, which is usually done by air liquefaction. This energy demand can substantially be lowered using thermally integrated separation modules based on ceramic oxygen transport membranes (OTM). It is least if the OTM is integrated in a 4-end mode, which entails that the permeating oxygen is swept and directly diluted using recirculated flue gas. Up to 60% reduction in capture energy demand compared to cryogenic air separation and up to 40% reduction compared to post-combustion capture approaches can be achieved. GREEN-CC will provide a new generation high-efficiency capture process based on oxyfuel combustion. The focus lies on the development of clear integration approaches for OTM-modules in power plants and cement industry considering minimum energy penalty related to common CO2 capture and integration in existing plants with minimum capital investment. This will be attained by using advanced process simulations and cost calculations. GREEN-CC will also explore the use of OTM-based oxyfuel combustion in different highly energy-demanding industrial processes, e.g. oil refining and petrochemical industry. However, highly permeable membrane materials show a chemical instability against CO2 and other flue gas components. One major challenge faced by GREEN-CC is therefore to identify and develop membrane materials, components, and a PoC-module for the 4-end mode OTM integration. The desired membrane assembly will consist of a thin membrane layer supported on substrates with engineered porosity and oxygen reduction catalysts with high and stable activity in flue gas. As proof of concept, a planar membrane module will be developed which involves technical hurdles like joining technology

Agency: European Commission | Branch: FP7 | Program: BSG-SME | Phase: SME-1 | Award Amount: 1.50M | Year: 2011

The present project, ALL4REST, is focused on the development of comfort-improved rest systems, using non-obstrusive technologies that promote deeper, more restorative sleep and prevent nocturnal awakenings. The successful solutions will reduce awakenings and/or reduce time to sleep after an awakening and reduce sleep onset latency. Within the global comfort improvement, physical and thermal parameters will be investigated, establishing quantitative and qualitative evaluation of comfort and sleep quality system. To achieve it, use of biomaterials and research of new ones, eco-friendly technologies and processes in fabrics destined to rest will allow the development of new products focused on obtaining an improved rest system.

Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: NMP.2012.2.3-1 | Award Amount: 1.34M | Year: 2012

Currently, there is a lack of consistent coordination between the activities of the various ETPs, which has led to a diverse range of ideas as to what is important to European materials developments, and consequently a somewhat fragmented support for these developments. In 2010, a group of ETPs (EuMaT, Suschem, Manufuture, FTC, ESTEP and SMR) with most significant material agenda, came together to create an Alliance for Materials (A4M). The driver for this collaboration was to ensure a Value Chain coverage to improve the speed of implementation of innovations in Europe that address the Grand Societal Challenges but with a clear attention to the competitiveness aspects too, in agreement with at least two of the pillars of Horizon 2020. Among the fundamental concepts of A4M is the Value Chain concept. It is regarded as the key element driving synergistic benefits through a common path which integrates players, resources and strategies starting from the fundamental aspects of materials science up to the industrial system that produces and/or transforms materials into valuable products. Alliance for Materials initiatives (A4M) is a new way of thinking; a partnership and networking in Materials Research and Innovation. With the MatVal proposal, A4M intends to enter into its crucial implementation phase creating the condition for a real enlargement of the network to the sector oriented ETPs active along the different value chains and concomitantly bringing together other relevant actors of the European Materials community, for a real integration of voices and visions. The key objectives include: To contribute to the implementation of the A4M view and strategy To integrate the diversity of ideas in Materials across ETPs To rely on a Value Chain based concept as main driver for a credible integration To speed up industrial exploitation of materials To pull together all the key materials technologies to support the Commission in establishing priorities

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2009.1.1 | Award Amount: 5.53M | Year: 2010

The main goal of the FARAMIR project is to research and develop techniques for increasing the radio environmental and spectral awareness of future wireless systems. The proposed holistic approach starts from the development of spectrum sensing hardware investigating how such functionality could be efficiently integrated to handheld devices. In the next step, we will combine measurements performed at multiple nodes in a cooperative fashion on a network level, not only to identify spectrum opportunities but also to localize any sources of primary transmissions or interference. This information will be fused to a radio environmental map, which provides the basis for system optimisation. Channel allocation, interference avoidance, and protocol parameter configuration are only selected examples for potential optimisation problems. The consortium will take a practical approach and prototype most of the project innovations showing their real-world value in radio resource optimisation.\n\nAdditionally, extensive spectrum measurements will be conducted at several locations in Europe to provide a valuable basis for spectrum modelling and increase the understanding how spectrum use changes in time, frequency, and space. This task will be implemented in an open access fashion not only enabling the community to access the measurement results but also allowing third-parties to benefit from the FARAMIR measurement setups. The results will naturally improve the design of the radio environmental map and the pursued optimisation solutions.\n\nThe high quality consortium possesses a unique combination of expertise from across the whole value chain of the wireless business starting from a semiconductor research institute, via an infrastructure and two complementary device manufacturers, to a network operator and a regulator, some of whom already participate in pertinent standardisation work. Additionally, four well-acclaimed university partners join their efforts in FARAMIR.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.6.6 | Award Amount: 14.63M | Year: 2011

ecoDriver addresses the need to consider the human element when encouraging green driving, since driver behaviour is a critical element in energy efficiency. The focus of the project is on technology working with the driver. The project aims to deliver the most effective feedback to drivers on green driving by optimising the driver-powertrain-environment feedback loop. It will carry out a substantial programme of work to investigate how best to win the support of the driver to obtain the most energy-efficient driving style for best energy use. Feedback coverage will include preview of the upcoming situation, optimising the current driving situation as well as post-drive feedback and learning. The project will address this across a wide range of vehicles -- e.g. cars, light trucks and vans, medium and heavy trucks and buses -- covering both individual and collective transport, and will optimise feedback to drivers for both nomadic devices and built-in systems and compare the effectiveness of each. The project will evaluate HMIs and feedback to drivers via both nomadic devices and built-in systems and compare the effectiveness of each. In each case a range of HMIs and feedback styles will be assessed. The project aims to examine driving not only with current and near-term powertrains but also with a full range of future vehicles, including various types of hybrid and plug-in electric vehicles. A comprehensive evaluation will be carried out both in the laboratory (a variety of driving simulators) and in real world driving in both the private and fleet contexts. Scenarios will be developed to assess the implications for the future effectiveness of green driving support. The target of ecoDriver is to deliver a 20% improvement in energy efficiency by autonomous means alone, which opens up the possibility of greater than 20% savings in combination with cooperative systems.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2007.6.2 | Award Amount: 21.57M | Year: 2008

The Intelligent Car Initiative has identified road safety, energy efficiency, and traffic congestion as the main challenges currently being faced by European transportation. Despite their severity, these issues may be improved with the use of new in-vehicle technologies currently not available in the market. However, implementing new technologies implies a risk to manufacturers. Factors such as different markets, user acceptance, and real-world driving conditions are difficult to assess before in-the-field testing. This restricts our capabilities for making the correct business and political decisions for deployment, and for understanding which aspects would benefit from further development the most. The goal of EuroFOT is to identify and coordinate an in-the-field testing of new Intelligent Vehicle Systems with the potential for improving the quality of European road traffic. This permits assessing their effectiveness on actual roads, while determining how they perform towards the intended objectives. In addition, this offers an early publicity of the technologies, and enables the analysis of the user acceptance and its subsequent potential for market penetration. This will be accomplished through a series of discrete steps. First, EuroFOT will specify a test plan identifying proper driving scenarios, factors with maximum safety potential, and expected results. Subsequent steps will involve the recruitment and training of customers, with the necessary installation of data loggers into their vehicles. In this way, customers will drive and collect data under normal driving conditions. During the final section, EuroFOT will analyse both objective and subjective data describing the driver behaviour and adaptation, vehicle dynamics, and system acceptance. This will permit EuroFOT to be considered representative of ordinary driving conditions in European roads, and ultimately evaluate the overall effectiveness and feasibility of Intelligent Vehicle Systems.

Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-EJD | Phase: MSCA-ITN-2015-EJD | Award Amount: 3.72M | Year: 2016

In many cases energy, water and resources contained in wastewater may have significant value if recovered. Therefore, the EU is currently confronted with a paradigm shift from wastewater treatment to resource recovery. To facilitate this shift, the SuPER-W European Joint Doctorate programme trains early-stage researchers (ESRs) in developing technologies for water, energy, nutrient and metal reuse, and bioproduction from (waste)water. The ESRs obtain knowledge and skills needed to turn environmental problems into economic opportunities. SuPER-W focuses not only on technology development through research, but the ESRs are also trained in translating research into policy, creative problem-solving, identification of bottlenecks for effective implementation of resource recovery technologies, development of business cases and urban/industrial ecosystems, and assessment of sustainability and the role of public perception and policy in innovation. Furthermore, they acquire a set of commercial, entrepreneurial and managerial skills that prepare them as future leaders. All ESRs are supervised by at least 2 promoters from 2 universities and co-supervised by a researcher from a non-academic partner organisation. Moreover, they conduct an internship in the non-academic sector in the first and last project year, contributing to more effective dissemination and exploitation of their research results. To organise the training, SuPER-W brings together leading researchers from 5 renowned universities and 12 associated non-academic partner organisations, including industrial partners involved in technology development, SMEs focused on consultancy/engineering, a service provider, a government agency, and professional network organisations. ESRs who successfully defend the PhD thesis and finish the doctoral training programme receive a double or joint PhD degree, jointly awarded by the universities of his/her promoters, as well as a joint doctoral training certificate of SuPER-W.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: GV-8-2015 | Award Amount: 8.20M | Year: 2016

Batteries are not yet the ideal energy container they were promised to be. They are expensive, fragile and potentially dangerous. Moreover the current EV cannot compete yet with traditional vehicles when it comes to driving range and flexibility. EVERLASTING intends to bring Li-ion batteries closer to this ideal by focusing on the following technology areas. Predicting the behavior of battery systems in all circumstances and over their full lifetime. This enables accurate dimensioning and choice of the correct battery type, leading to lower cost. It also facilitates the development of a powerful battery management system during all stages of its evolution from idea to fully tested product. Sensing signals beyond the standard parameters of current, voltage and temperature. This multi-sensing approach provides more varied and in-depth data on the status of the battery facilitating a pro-active and effective management of the batteries, preventing issues rather than mitigating them. Monitoring the status of the battery by interpreting the rich sensor data. By intelligently combining this information with road, vehicle and driver data we intend to offer accurate higher-level driver feedback. This induces a bigger trust and hence a lower range anxiety. Managing the battery in a proactive way, based on a correct assessment of its status. Efficient thermal management and load management results in increased reliability and safety and leads to lower overall cost through an increased lifetime. Defining a standard BMS architecture and interfaces and gathering the necessary support in the market. This allows an industry of standard BMS components to flourish which will result in lower cost.

Agency: European Commission | Branch: H2020 | Program: ERC-ADG | Phase: ERC-ADG-2015 | Award Amount: 2.38M | Year: 2016

One of the great mysteries in the natural sciences is the dominance of matter over antimatter in the universe. According to our present understanding, the early universe contained the same amount of matter and antimatter. If the universe had behaved symmetrically as it developed, every particle would have been annihilated by one of its antiparticles. We therefore owe our very existence to mechanisms that have led to a world where something that we call matter remains. We propose to study such mechanisms by searching for electric dipole moments (EDMs) of charged hadrons in a new class of precision storage rings. Our project will lay the foundations for a new European flagship research infrastructure. The breaking of the combined charge conjugation and parity symmetries (CP-violation) in the Standard Model is not strong enough to explain the observed excess of matter and further sources of CP-violation must be sought. These sources could manifest themselves in Electric Dipole Moments of elementary particles, which occur when the centroids of positive and negative charges are mutually and permanently displaced. The observation of an electric dipole moment will elucidate the mechanisms which led to the matter that dominates the universe. Although the measurement principle, the time development of the polarization vector subject to a perpendicular electric field, is simple, the smallness of the effect makes this an enormously challenging project. This can only be mastered through the common effort of an international team of accelerator and particle physicists, working closely with engineers. The proponents of this design study and the research environment at the Forschungszentrum Jlich (Germany), including the conventional storage ring COSY, provide the optimal basis for one of the most spectacular possibilities in modern science: finding an EDM as a signal for new physics beyond the Standard Model and perhaps explaining the puzzle of our existence.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: GC.SST.2011.7-10. | Award Amount: 4.23M | Year: 2011

CO2 emissions, noise emissions and other negative impacts caused by present urban delivery concepts and specifically by the delivery vehicles are unsustainable in present and future European urban life. Fully electric light delivery vehicles (LDV) not only offer zero local CO2 emissions and close-to-zero noise emissions. The change in propulsion technology from ICE to electric powertrains will lead to the integration of new components and systems, while others undergo changes or become obsolete. The possibility to integrate the electric motor into the wheel further increases the design freedom, especially if also suspension and regenerative braking can be integrated into it. This opens up new freedom in design and clears the way for new urban delivery vehicle concepts. DELIVER is to produce and physically showcase design research results that allow for full exploitation of this new freedom, while responding to changing future market demands. To achieve this key objective, the project generates, investigates and analyzes innovative design concepts for electric LDVs with motorized wheels. It delivers a range of advanced architectures which enable at least the same high level of intrinsic safety as known from current best in class conventional vehicles at minimal weight, maximised energy efficiency (40 % better than best-in-class ICE benchmark), optimized ergonomics & loading space at affordable costs as well as acceptable levels of comfort and driving performance. The program will culminate in a driving concept validation vehicle which will embody the optimum integration of systems as researched during the design and development stage. The purpose of the vehicle is to validate the research results with the highest degree of reality possible within the budget. Some specific targets will be verified by simulation such as crash. DELIVER can achieve substantial impact due to the strong involvement of leading industrial partners.

Wang L.,RWTH Aachen | Wang L.,Shanghai JiaoTong University
Journal of Fluid Mechanics | Year: 2010

Geometrical and dynamical properties of turbulent flows have been investigated by streamline segment analysis. Starting from each grid point, a streamline segment is defined as the part of its streamline bounded by the two adjacent extremal points of the velocity magnitude. Physically the streamline segments can be extended into a more meaningful concept, namely the streamtube segments, which are non-overlapping and space filling. This decomposition of the flow allows for new insights into vector-related statistics in turbulence. According to the variation of velocity, the streamline segments can be sorted into positive and negative segments. The overall properties of turbulent flows can be newly understood and explained from the statistics of these segments with simple structures; for instance, the negative skewness of the velocity derivative becomes naturally a kinematic outcome. Furthermore, from direct numerical simulations conditional statistics of pressure and kinetic energy dissipation along the streamline segments are evaluated and discussed. © 2010 Cambridge University Press.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: FI.ICT-2011.1.8 | Award Amount: 19.26M | Year: 2013

Change is the name of the game in energy! The shift to sustainability is visible everywhere. It is now a European priority to combine solutions which utilise energy generation from renewable energy sources and optimize energy usage efficiency into a Smart Energy System based on the introduction of Future Internet technologies. At the same time, business innovation needs to be encouraged to ensure that job creating SMEs can thrive in the new energy eco-system. FINESCE will organize and run user trials in 7 European countries, building on investments of billions of Euro, addressing efficient energy usage in residential and industrial buildings, developing a new prosumer energy marketplace, building a cross-border private virtual power plant, and using electric vehicles as an element of demand response systems, enabling energy providers to move from reactive to pro-active energy network management by providing them with Future Internet ICT, enabling them to better balance volatile solar and wind energy generation with demand for energy. The FINESCE trials will prove the practical applicability of Future Internet technologies and the FI-WARE Generic Enablers to the challenges of the energy sector. FINESCE will develop an active community of innovative SMEs, preparing them for the exploitation of the emerging business opportunities in energy, creating jobs, social impact and economic growth. FINESCE builds on and extends the results of the FI-PPP FINSENY project to realise sustainable real time smart energy services.The consortium includes globally leading energy and ICT operators, manufacturers and service providers and outstanding research organisations and SMEs, from 15 countries, contributing directly to tightly focused trials and business innovation. It has the scale and scope to ensure that the FINESCE results drive the FI-WARE and Future Internet success and long-term exploitation internationally.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: NMP.2011.3.2-1 | Award Amount: 4.58M | Year: 2012

Transition of processing industries towards a more sustainable model of manufacturing is one of key priority topics for European Research Area. This transition requires adoption of novel reactor technologies, greener reactions and the increase in the use of intelligent systems in processing industries. The latter means improving processes through use of real-time information and ability to affect processes in real time. The long-term vision of COOPOL is to develop new methods and tools for modeling and control, based on real-time sensing, which will facilitate the development of a new paradigm of processes: intensive, low-impact, sustainable chemical technologies. The COOPOL consortium is focusing on one of the key areas of interest to European Chemical Industries, namely the polymer industry. Within the chemicals sector polymer production plays a significant role, with European market share of 25% and providing employment to 1.6 million people within EU27. Many polymer products are manufactured using batch and semi-batch reactors. In most cases the process parameters, such as temperature profile, feeds, etc follow a specific time schedule, which has been fixed after an expensive period of product and process development. This tight recipe schedule is sensitive against disturbances e.g., unexpected variation in operating conditions, variation in feed purity etc., which inevitably leads to variations in polymer structure andto inter-batch variability and off-spec products. Furthermore, the use of empirically determined recipes with fixed-time controls does not allow intensification of the process which requires time-varying feeds and reactor temperature to run the reaction faster and hence closer to its limits, and also to switching from a semi-batch to other reactor or process types. COOPOL addresses the complex issues of real-time process control based on advanced models and on-line sensors, to develop a generic basis for widely applicable sustainable intensified processes. COOPOL will develop a new process control approach, linking molecular level information and understanding of the reaction chemistry with real-time sensing, rigorous modeling based on first principles, subsequent model reduction and non-linear model-predictive control (NMPC) with economic objectives, called dynamic real-time optimisation (DRTO). The approach of COOPOL is to develop robust real-time optimisation-based control and sensing methodologies and through their application to achieve, in parallel, the intensification of (i) the existing processes, and (ii) the development of novel intensive smart-scale processes. The approach of COOPOL will deliver significant advance in the state-of-the-art in model-based predictive control and at the same time produce tangible and exploitable benefits for European industry in the short, medium and long-term.

« Volvo Cars to launch UK’s largest autonomous driving trial | Main | Onboard Dynamics receives $3M from ARPA-E, others for innovative CNG refueling technology » Volkswagen is working with partners from industry and science on the German Federal Ministry for Economic Affairs and Energy’s SLAM research project (Schnellladenetz für Achsen und Metropolen, Fast charging network for road axes and metropolitan areas). The SLAM project has a total budget of €12.9 million (US$14.6 million) and will receive support from the Federal Ministry for Economic Affairs and Energy to the extent of €8.7 million (US$9.8 million) by August 2017. The German government designated SLAM as one of seven “flagship projects in electric mobility”. A central component of SLAM is the “Golden Test Device” prototype co-developed by Volkswagen which will be unveiled at the Hannover Messe industrial trade show. The Golden Test Device is a standardized testing device to check quickly and cost-effectively the compatibility of new electric vehicles and charging stations produced by different manufacturers. A further aim is to provide an internationally accepted testing reference for connecting electric vehicles to charging stations. Volkswagen will be showing a prototype of the device at the joint stand of the United States Department of Energy/ANL and the Joint Research Centre of the European Commission at the Hannover Messe. Volkswagen took into account all the technical requirements for vehicles and charging stations and defined various test scenarios in collaboration with national and international partners to develop the device. SLAM’s mission includes setting up a fund-based research network of up to 600 fast-charging stations to collect basic data for the research and analysis of suitable charging infrastructures according to the CCS-DC standard (combined charging system). This includes simulation and location scenarios to forecast demand for new charging stations, developing business models for site operators and a uniform access and billing system. SLAM includes the development of CCS to support charging at more than 150 kW and also takes into account conditions for private investors. Volkswagen’s project partners are the BMW Group, Daimler AG, Porsche AG, Deutscher Genossenschaftsverlag, EnBW, the RWTH Aachen University and the Institute of Human Factors and Technology Management (IAT, Stuttgart).

« ROEV Association forms to promote public EV charging interoperability | Main | Renault-Nissan Alliance installing 90 new charge spots for COP21 summit in Paris » Researchers of the Institute for Advanced Sustainability Studies (IASS) in Potsdam and the Karlsruhe Institute of Technology (KIT) have achieved the proof-of-principle for a innovative technique to extract hydrogen (H ) from methane (CH ) without the formation of CO as a byproduct. At this stage, cost estimates are uncertain, since methane cracking is not yet a fully mature technology. However, preliminary calculations show that it could achieve costs of €1.9 to €3.3 per kilogram of hydrogen at German natural gas prices—without taking the market value of the solid black carbon byproduct of the process into consideration. Most of the world’s hydrogen production is currently based on conventional technologies such as steam methane forming (SMR), which also uses natural gas as feedstock but releases significant amounts of carbon dioxide in the process. CO emissions from the ammonia industry alone amount to approximately 200 million tons per year—by comparison, Germany generates around 800 million tons of carbon dioxide per year. By contrast, methane cracking—the separation of methane’s hydrogen and carbon molecular components—occurs at high temperatures (750°C and above) but does not release any harmful emissions. The main by-product of methane cracking—solid black carbon—is also an increasingly important industrial commodity. It is already widely employed in the production of steel, carbon fibres and many carbon-based structural materials. The black carbon derived from the novel cracking process is of high quality and is a particularly pure powder. Its value as a marketable product therefore enhances the economic viability of methane cracking. Alternatively, black carbon can be stored away, using procedures that are much simpler, safer and cheaper than the storing of carbon dioxide. Methane cracking itself is not an entirely new idea: in the last two decades, many experiments in different institutions have been carried out that have proven its technical feasibility. But these past attempts were limited by issues such as carbon clogging and low conversion rates. The IASS and KIT team built an experimental reactor that could demonstrate the potential of methane cracking and overcome previous obstacles. The starting point is a novel reactor design, as proposed by Nobel Laureate and former IASS Scientific Director Professor Carlo Rubbia and that is based on liquid metal technology. Fine methane bubbles are injected at the bottom of a column filled with molten tin. The cracking reaction happens when these bubbles rise to the surface of the liquid metal. Carbon separates on the surface of the bubbles and is deposited as a powder at the top end of the reactor when they disintegrate. This idea was put to the test during a series of experimental campaigns that ran from late 2012 to the spring of 2015 in KIT’s KALLA (KArlsruhe Liquid Metal LAboratory). Researchers were able to evaluate different parameters and options, such as temperature, construction materials and residence time. The final design is a 1.2-meter-high device made of a combination of quartz and stainless steel, which uses both pure tin and a packed bed structure consisting of pieces of quartz. The innovative reactor is resistant to corrosion, and clogging is avoided because the microgranular carbon powder produced can be easily separated. The reactor thus satisfies the technical preconditions that would be needed for the continuous operation of an industrial-scale reactor. While these remain laboratory-scale experiments, researchers can extrapolate from them to gain insights into how methane cracking could be integrated into the energy system and, more specifically, what its contribution to sustainability could be. To this end, the IASS is collaborating with RWTH Aachen University to conduct a life cycle assessment (LCA) of a hypothetical commercial methane cracking device based on a scaling-up of our prototype. The LCA assumes that some of the produced hydrogen is used to generate the required process heat. The compared hydrogen production technologies were steam methane reforming (SMR) and water electrolysis coupled with renewable electricity. With respect to emissions of carbon dioxide equivalent per unit of hydrogen, the LCA showed that methane cracking is comparable to water electrolysis and more than 50% cleaner than SMR. In the next phase of the process, the IASS and KIT will focus on optimising some aspects of the reactor design, such as the carbon removal process, and progressively scaling it up to accommodate higher flow rates.

News Article | November 10, 2016
Site: www.prweb.com

Kinases play important roles in many biological signaling pathways, as an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates. Kinase inhibitors are, therefore, potentially found as actives in typical phenotypic screens. DiscoverX is sponsoring a free webinar on the interplay of kinase broad profiling and phenotypic screening, which will provide details on the design of the Janssen kinase inhibitor broad profiling project and its impact on general early kinase drug discovery projects. The team at Janssen Research & Development will be sharing two examples during this webinar, the mouse embryonic stem cell stemness assay, run in collaboration with Dundee DSTT, and the literature reported splicing corrector assay of pre-Lamin A. They will share results of how kinase inhibitor broad profiling and chem-bioinformatic analyses developed in the IMI OpenPhacts consortium can impact target deconvolution after phenotypic screening. The outcomes of these analyses are lists of potential kinase targets for further biological validation. DiscoverX has arranged for Dr. Edgar Jacoby, senior principal scientist in computational chemistry at Janssen Research & Development, to be the presenter during this webinar. Jacoby received his doctorate in computational chemistry from RWTH Aachen University, before doing post-doctoral work in molecular biophysics at Harvard Medical School and the University of Chicago. In 2013, he joined Janssen Research & Development as a senior principal scientist in computational chemistry. Prior to joining Janssen Research & Development, Jacoby worked at Servier doing research framework in molecular modeling. He has also worked at the Combinatorial Chemistry Group at Novartis Central Technologies as lab head for the in-silico design of combinatorial compound libraries, as well as led the Molecular and Library Informatics Group in the Novartis Center of Proteomic Chemistry in Basel from 2002 to 2012. LabRoots will host the webinar December 7, 2016, beginning at 9:00 a.m. PT, 12:00 p.m. ET. To learn more about this event, or to register for free, click here. About DiscoverX DiscoverX Corporation, headquartered in Fremont, CA, USA, is a leader in the design, manufacture and sale of biochemical and cell-based assays for the drug discovery & life science markets. This industry-leading portfolio of products and services, under the KINOMEscan®, PathHunter® and BioMAP® brands, are used to aid life science research and enable rapid development of safe and effective biologic and small molecule drugs, by improving research productivity, effectiveness of screening, lead optimization & bioanalytical campaigns, as well as providing predictive tools that deliver physiologically relevant insights on drug molecules from early discovery through pre-clinical development. DiscoverX embodies an innovative approach to creating life science tools that have been widely adopted across the globe in pharmaceutical, biotechnology and academic laboratories. About LabRoots LabRoots is the leading scientific social networking website and producer of educational virtual events and webinars. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

News Article | December 15, 2016
Site: www.eurekalert.org

Professor Britta Nestler of Karlsruhe Institute of Technology (KIT) is granted the 2017 Gottfried Wilhelm Leibniz Prize by the German Research Foundation (DFG). With this highest endowed German science prize in the amount of EUR 2.5 million, DFG honors the mathematician and physicist for her research into computer-aided materials modeling. "Professor Britta Nestler most successfully conducts interdisciplinary computer-aided materials research and is among the top scientists in her discipline," says the President of KIT, Professor Holger Hanselka. "In 2001, she was Germany's youngest professor and since then has been granted a number of prizes, including the State Research Award of Baden-Württemberg in 2007. She very much deserves the Leibniz Prize and we are proud of Britta Nestler." "The career of Britta Nestler is a success story," says Professor Oliver Kraft, KIT Vice President for Research. "She is an excellent and highly committed scientist, who has largely influenced her discipline in Germany. I am very pleased that she now receives the most important research prize in Germany. This once again reflects our scientists' strength in research. Congratulations to Britta Nestler." How does the microstructure of a material develop during production, i.e. during casting or rolling of sheet metal? Which influence does heat or mechanical loading have on the service life of e.g. power plant boilers or solar facilities? To answer these questions, Britta Nestler studies the microstructures of materials by means of computer-aided simulations. She combines expertise in materials science and software technology and develops realistic three-dimensional models of materials based on multiscaled and multiphysical approaches. Theoretical findings obtained from microstructure modeling on supercomputers are incorporated in close-to-practice research projects together with industry, among others to improve brake disks, corrosion prognoses, and medical diagnostics. Her studies, among others, focus on the structure of crystals, fabrication processes, porous media, crack propagation, or phase transition between the liquid and solid when alloys solidify. As a materials researcher, she cooperates with geologists to analyze e.g. the formation of grain structures in rock and helps better understand the processes of geological history and use of geothermal energy. In cooperation with energy researchers, she develops foam structures within integrated phase change materials for use in latent heat storage systems. Since 2010, Britta Nestler has been conducting research and teaching at Karlsruhe Institute of Technology (KIT), where she is member of the Board of Directors of the Institute for Applied Materials. In addition, she was appointed Director of the Computational Materials Science and Engineering Department of the Institute of Materials and Processes of Karlsruhe University of Applied Sciences (HsKA) in 2008. In the same year, she established the Steinbeis Transfer Center "Materials Simulation and Process Optimization" that is also headed by her. Since 2001, Nestler has been professor of HsKA. Before, she spent several research periods abroad and also worked in industry. Britta Nestler has four children. In 2000, Britta Nestler was conferred her doctorate by RWTH Aachen University, where she previously received her diplomas in physics and mathematics. As a third subject, she studied pedagogics. Among the prizes she received so far is the State Award for Applied Research (2007) of the Baden-Württemberg Ministry of Science, Research, and the Arts. Together with the Department of Informatics of Karlsruhe University of Applied Sciences, she received the State Teaching Award (2009). In addition, Nestler was granted the Research Prize of Karlsruhe University of Applied Sciences in 2014, the Materials Science and Technology Prize of the Federal of European Materials Societies (FEMS) in 2004, and the Richard von Mises Prize of the Society for Applied Mathematics and Mechanics (GAMM) in 2002. Since 2010, Nestler has succeeded in acquiring funding for research and education in the amount of more than EUR 5.5 million. Apart from Britta Nestler, seven scientists of KIT have been granted the Leibniz Prize by DFG so far. Since 1986, the Leibniz Prize has been awarded annually by DFG. It was established to honor outstanding scientists for research in all areas of science. The prize money in the amount of about EUR 2.5 million can be spent by the winners according to their own ideas and without bureaucratic expenditure for their scientific work within a period of up to seven years. This year, the Leibniz Prize goes to ten scientists. So far, 348 researchers have won the Prize that is considered one of the most important science awards worldwide. Seven Leibniz Prize winners were awarded the Nobel Prize afterwards. The Leibniz Prizes will be handed over on March 15, 2017 in Berlin. Karlsruhe Institute of Technology (KIT) pools its three core tasks of research, higher education, and innovation in a mission. With about 9,300 employees and 25,000 students, KIT is one of the big institutions of research and higher education in natural sciences and engineering in Europe. KIT - The Research University in the Helmholtz Association Since 2010, the KIT has been certified as a family-friendly university.

News Article | March 11, 2016
Site: www.materialstoday.com

The organizers of the International Glass Fiber Symposium, taking place from 17–19 October 2016 in Aachen, Germany, have released details of the event. According to the Institut für Textiltechnik of the RWTH Aachen University (ITA) and the Institute of Mineral Engineering of RWTH Aachen University (GHI), the aim of the conference is to build a bridge from the manufacturing of the glass fibers to the composite material users covering every intermediate step. The conference will feature producers as well as operators to exchange information on the latest developments in the field. Problems can be discussed from the producers as well as the operator’s point-of-view. ‘Many conferences are aligned exclusively to topics like 'carbon fibers' or generally focus on fiber composite structures,’ the organizers said in a press release. ‘The topic 'glass fibers' mostly takes a backseat and is never focused on its own although the market of high modulus fibers consists up to 90% of glass fibers. This is the reason why the conference offers an ideal ground to cover the whole topic from raw material all the way to the end-product.’ This story uses material from RWTH Aachen University, with editorial changes made by Materials Today. The views expressed in this article do not necessarily represent those of Elsevier.

News Article | November 29, 2016
Site: www.eurekalert.org

Research networks to investigate topics such as practices of comparison, neutrinos, dark matter, and the robustness of vision; around €120 million in funding for an initial 4-year period The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) will establish 14 new Collaborative Research Centres (CRCs). This was decided by the responsible Grants Committee during its autumn session in Bonn. The new CRCs will receive a total of 117.4 million euros in funding. There will also be a 22 percent programme allowance for indirect project costs. Seven of the 14 networks set up are CRC/Transregios, which will be spread across multiple research sites. All of the new CRCs will be funded for an initial four-year period starting on 1 January 2017. In addition to the 14 new Collaborative Research Centres, the Grants Committee also approved the extension of 15 existing CRCs for an additional funding period. As a result, the DFG will be funding a total of 268 Collaborative Research Centres from January 2017. The new Collaborative Research Centres in detail (in alphabetical order by their host universities, including the name of the applicant universities): Little is currently known about the history, social and cultural causes, functions and impacts of comparison - despite frequent speculation about the increase in comparisons in certain epochs and in modern societies. In the Collaborative Research Centre "Practices of Comparisons: Ordering and Changing the World", researchers from the fields of history, literature studies, philosophy, history of art, political science and law will investigate how the historically variable practices of comparison link to routines, rules, institutions and discourses - and can thus create structures but also trigger medium-range dynamics or overarching change. (Host university: Bielefeld University, Spokesperson: Professor Dr. Angelika Epple) Industrial forming processes for metals cause damage within the material. It is not known how the damage caused by forming processes such as rolling or deep-drawing is influenced, how it changes throughout the process chain or what impact it has on subsequent component behaviour. The CRC/Transregio "Damage Controlled Forming Processes" therefore aims to develop new methods and technologies to control and predict damage as well as component characteristics. (Host university: Technical University of Dortmund, Spokesperson: Professor Dr.-Ing. A. Erman Tekkaya; additional applicant university: RWTH Aachen University) The aim of the CRC/Transregio "Mobile Material Characterisation and Localisation by Electromagnetic Sensing" is to trial new approaches to mobile material detectors. This would enable the material properties of any object to be determined, even if it were concealed behind a wall, making it possible to locate unconscious persons in a building filled with smoke or contaminated with poisonous gases, or to detect burning cables inside walls, for example. To achieve this it is necessary to develop mobile detectors that record data in a frequency range from several gigahertz to terahertz, which can be used to precisely localise and characterise a complex environment. (Host university: University of Duisburg-Essen, Spokesperson: Professor Dr.-Ing. Thomas Kaiser; additional applicant university: University of Bochum) Myeloid cells - the immune cells of the brain - play an important role in the function of the central nervous system. They are the focus of the work of the CRC/Transregio "Development, Function and Potential of Myeloid Cells in the Central Nervous System (NeuroMac)". Using some of the latest methods in molecular immunology and neuroscience, such as in-vivo microscopy and genome editing, the researchers will investigate the role of myeloid cells in diseases such as stroke, multiple sclerosis, Alzheimer's and Huntington's disease. (Host university: University of Freiburg, Spokesperson: Professor Dr. Marco Prinz; additional applicant universities: Free University of Berlin and Humboldt University of Berlin) The Collaborative Research Centre "N-Heteropolycycles as Functional Materials" is concerned with the field of organic electronics and will investigate new, entirely organic semiconductors. As the fundamental building blocks for semiconductors, the research network will use what are known as N-heteropolycycles and study their characteristics. The researchers intend to address the complete spectrum of chemical synthesis, method development and the physical and theoretical characterisation of organic semiconductors, including the question of the effects of the material properties of N-heteropolycycles in optoelectronic components, such as solar cells. (Host university: University of Heidelberg, Spokesperson: Professor Dr. Lutz H. Gade) In algebra, where exact calculations are essential, modern high-performance computers with mathematical software have enormous computing potential which so far has not been fully exploited. The researchers in the CRC/Transregio "Symbolic Tools in Mathematics and their Application" plan to further develop existing computer algebra systems which they have largely developed themselves and in doing so, answer fundamental questions in mathematics. They also plan to make the software available as an open-source system. (Host university: Technical University of Kaiserslautern, Spokesperson: Professor Dr. Gunter Malle; additional applicant universities: RWTH Aachen University; Saarland University) Symplectic geometry has its roots in classical mechanics, where it enables a coordinate-free formulation of the basic equations of motion and therefore a deeper understanding of the underlying dynamics. The CRC/Transregio "Symplectic Structures in Geometry, Algebra and Dynamics" will investigate symplectic structures and the application of symplectic techniques to topics in geometry, algebra, dynamic systems, topology, combinatorics and optimisation. The network will forge links with disciplines in which the potential of a symplectic approach has been little or not fully realised or which themselves can contribute new methodologies to the study of symplectic questions, for example computer science. (Host university: University of Cologne, Spokesperson: Professor Dr. Hansjörg Geiges; additional applicant university: University of Bochum) How is information organised and structured in language? The factor of 'prominence' plays a central role in the formation of language structures. Through its formulated question, the Collaborative Research Centre "Prominence in Language" will bring together many areas of linguistics, such as phonetics/phonology, morphology, syntax, semantics, pragmatics and discourse. It will also investigate the relationships between linguistic prominence and general cognitive mechanisms such as the accentuation of attention, thus forging links with psychology and clinical linguistics. (Host university: University of Cologne, Spokesperson: Professor Dr. Klaus von Heusinger) Contrary to a long-held view, bacteria are highly organised units whose function is guaranteed by the precise positioning of biomolecules inside them. The CRC/Transregio "Spatiotemporal Dynamics of Bacterial Cells" will consider many different aspects of cellular organisation, such as the spatiotemporal regulation of cell division, growth and morphogenesis, the organisation and segregation of chromosomal DNA and the dynamics of the formation of (membrane) protein complexes. In this way, the CRC/Transregio aims to identify the molecular systems responsible for controlling these cellular processes and better understand the spatiotemporal dynamics of bacterial cells. (Host university: University of Marburg, Spokesperson: Professor Dr. Martin Rudolf Thanbichler; additional applicant university: LMU Munich) The CRC/Transregio "Rationality and Competition: The Economic Performance of Individuals and Firms" brings together representatives of behavioural economics and neoclassical economics. They aim to explain how distortions and anomalies in the behaviour of individuals and companies are connected and what economic policy measures can effectively protect consumers and employees against poor decisions and exploitation. (Host university: LMU Munich, Spokesperson: Professor Dr. Klaus Schmidt; additional applicant university: Humboldt University of Berlin) A Munich-based Collaborative Research Centre will investigate "Neutrinos and Dark Matter in Astro- and Particle Physics (NDM)". The researchers are primarily interested in neutrinos, the most common particles of matter in the universe, and dark matter, which is responsible for cosmic dynamics on galactic and even larger scales. Among the topics they will address is the still unanswered question of whether neutrinos are their own antiparticles and whether they have sterile partners. The answer to this question could explain why our world consists of more matter than antimatter. (Host university: Technical University of Munich, Spokesperson: Professor Dr. Elisa Resconi) The high resource demands of construction, a fast-growing world population, especially in urban areas, and the changing needs of inhabitants create a need for fundamentally new architectural concepts. The aim of the Collaborative Research Centre "Adaptive Envelopes and Structures for the Future Built Environment" is therefore to develop concepts for adaptive buildings. The network will investigate the potential of adaptive elements for load-bearing structures, envelope systems and interior fittings, with a view to designing buildings which can actively react to external influences. (Host university: University of Stuttgart, Spokesperson: Professor Dr.-Ing. Werner Sobek) Our sense of sight enables us to identify objects reliably even under very different conditions; we therefore have robust visual inference. This ability demands complex calculations, which are performed by the nerve cells in the visual system. The aim of the Collaborative Research Centre "Robust Vision - Inference Principles and Neural Mechanisms" is to uncover the principles and algorithms that make robust vision possible. The researchers will also use technical algorithms of human learning and computer vision research to draw conclusions about biological vision. (Host university: University of Tübingen, Spokesperson: Professor Dr. Matthias Bethge) Predicting the extent to which pollutants will remain in and alter our landscapes in the long term is a major challenge in geosciences and environmental research, all the more so as the extremely complex processes are very difficult to measure with laboratory experiments. The Collaborative Research Centre "Catchments as Reactors: Metabolism of Pollutants on the Landscape Scale (CAMPOS)" will therefore investigate the transport and conversion of pollutants in the large-scale and long-term process chains found in nature. The researchers will utilise innovative observation systems and numerical landscape models with a view to laying the foundations for more reliable predictions about future soil and water quality in the face of climate and land use change. (Host university: University of Tübingen, Spokesperson: Professor Dr. Peter Grathwohl) Further information will be provided by the spokespersons of the Collaborative Research Centres. Contact at the DFG Head Office: Dr. Klaus Wehrberger, Head of the Research Centres Division, Tel. +49 228 885-2355, Klaus.Wehrberger@dfg.de More details about the funding programme and the funded Collaborative Research Centres are available at: http://www.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: NMP-2008-3.4-1 | Award Amount: 11.94M | Year: 2009

The project uttermost objective is to foster and strengthen the primacy of Future European Manufacturing by defining the next generation Virtual Factory Framework. The VFF will promote major time and cost savings while increasing performance in the design, management, evaluation and reconfiguration of new or existing facilities, supporting the capability to simulate dynamic complex behaviour over the whole life cycle of Factory, approached as a complex long living Product. Thus the project will research and implement the underlying models and ideas at the foundation of a new conceptual framework designed to implement the next generation Virtual Factory, also meant to lay the basis for future applications in this research area. This approach identifies four key Pillars: a Reference Model for factory planning, based on the new industrial key paradigm Factory as a Product; the VF Manager core, meant to handle the common space of abstract objects representing the Factory; a set of decoupled Functional Modules for supporting the factory design, reconfiguration, evaluation, management, and a Integration of Knowledge at different layers as engine for the modules aiming at giving reality to the envisioned Learning Factory. The Virtual Factory, deployed according to the VFF concept, has to be permanently synchronised with the Real Factory aiming to achieve time and cost savings in the design, ramp-up, management, evaluation and reconfiguration of the Real Production itself. The proposed pillars foster the implementation of a holistic, modular, open and scalable Virtual Factory meant to achieve clear, well identified and measurable goals for the real production system according to quantitative indicators/measures: Time for factory design, re-configuration, re-engineering -50%; Ramp-up time -30%; Capability Index Cp >=2.0. Moreover, a strong qualitative factor has to be considered: Democratisation.

The overall objective of PARADDISE project is to rationalize, to structure and to make available to the stakeholders of manufacturing value chain the knowledge and the tools for combining two antithetical processes: Laser Metal Deposition (LMD) and Machining (milling and turning). The project will develop expert CAx technologies, smart components and monitoring and control systems tailored for the hybrid process in a cost-effective way and with structured knowledge about LMD process. The PARADDISE solution will offer a synergetic combination among: i) the high flexibility for the designs and for the materials to be used, the high material efficiency and the high savings in material resources and its associated costs of the LMD operations; and ii) the high accuracy, the high robustness and the high productivity of subtractive operations. The solution will be integrated in the ZVH45/1600 Add\Process hybrid machine from IBARMIA manufacturer (PARADDISE partner), which is already available in the market as well as at TECNALIAs facilities (PARADDISE coordinator). Thus, the PARADDISE project will conceive a process-machine-tools solution. By means of this combined manufacturing process, large scale manufacturers of value-added metallic components will be able to achieve high quality and high productivity with a minimum use of material and energy resources when manufacturing those parts, which will lead to a reduction in manufacturing costs. In that way, the PARADDISE project intends to boost and to spread the use of Laser Metal Deposition (LMD) technology along the life cycle of value-adding metal components.

Beneke M.,RWTH Aachen | Falgari P.,University Utrecht | Klein S.,RWTH Aachen | Schwinn C.,Albert Ludwigs University of Freiburg
Nuclear Physics B | Year: 2012

We compute the total top-quark pair production cross section at the Tevatron and LHC based on approximate NNLO results, and on the summation of threshold logarithms and Coulomb enhancements to all orders with next-to-next-to-leading logarithmic (NNLL) accuracy, including bound-state effects. We findσtt̄(Tevatron)=(7.22-0.47+0.31-0.55+0.71) pb,σtt̄(LHC,s=7 TeV)=(162.6-7.6+7.4-14.7+15.4) pb for mt=173.3 GeV. The implementation of joint soft and Coulomb resummation, its ambiguities, and the present theoretical uncertainty are discussed in detail. We further obtain new approximate results at N3LO. © 2011 Elsevier B.V..

Dewald U.,Karlsruhe Institute of Technology | Fromhold-Eisebith M.,RWTH Aachen
Environmental Innovation and Societal Transitions | Year: 2015

This paper proposes that spatial dynamics of new environmental technologies can be better understood when positioned in a multi-scalar theoretical framework based on innovation system approaches. We combine territorial innovation system concepts with a technological innovation systems (TIS) perspective. The investigation of photovoltaic (PV) technology in Germany indicates that the relevance of different scales and actor constellations shifts in the course of a 'maturing' innovation system. First, the convergence of regional and institutional subsystems forms a temporary window of opportunity for a robust TIS formation within a national framing. Second, consolidation according to basic patterns of the underlying national innovation system takes place. This is illustrated by the robust performance of German mechanical PV equipment suppliers within a globalized PV value chain. The empirical findings allow for drafting a theoretical framework that offers a generalized view on this shifting spatial context pattern of an emerging environmental technology. © 2015 Elsevier B.V. All rights reserved.

Jahnen-Dechent W.,RWTH Aachen | Heiss A.,RWTH Aachen | Schafer C.,RWTH Aachen | Ketteler M.,Klinikum Coburg GmbH
Circulation Research | Year: 2011

The final step of biomineralization is a chemical precipitation reaction that occurs spontaneously in supersaturated or metastable salt solutions. Genetic programs direct precursor cells into a mineralization-competent state in physiological bone formation (osteogenesis) and in pathological mineralization (ectopic mineralization or calcification). Therefore, all tissues not meant to mineralize must be actively protected against chance precipitation of mineral. Fetuin-A is a liver-derived blood protein that acts as a potent inhibitor of ectopic mineralization. Monomeric fetuin-A protein binds small clusters of calcium and phosphate. This interaction results in the formation of prenucleation cluster-laden fetuin-A monomers, calciprotein monomers, and considerably larger aggregates of protein and mineral calciprotein particles. Both monomeric and aggregate forms of fetuin-A mineral accrue acidic plasma protein including albumin, thus stabilizing supersaturated and metastable mineral ion solutions as colloids. Hence, fetuin-A is a mineral carrier protein and a systemic inhibitor of pathological mineralization complementing local inhibitors that act in a cell-restricted or tissue-restricted fashion. Fetuin-A deficiency is associated with soft tissue calcification in mice and humans. © 2011 American Heart Association, Inc.

Zalesskiy S.S.,RAS N. D. Zelinsky Institute of Organic Chemistry | Danieli E.,RWTH Aachen | Blumich B.,RWTH Aachen | Ananikov V.P.,Saint Petersburg State University
Chemical Reviews | Year: 2014

The unique feature of the NMR approach is the diversity of chemical and physical properties at different structural levels that can be accessed using a single instrument. The state-of-the-art of modern science brings a number of outstanding research challenges. In the field of chemistry, these include green chemistry procedures, especially cost-efficient and sustainable production of chemicals and pharmaceuticals. Highly efficient, selective, stable, and recyclable catalysts as well as protocols for asymmetric transformations are key requirements for modern catalysis. NMR spectroscopy has been recognized as a valuable tool for promoting research in organic synthesis and catalysis. Another milestone en route to reducing the size of NMR equipment was the improvement of sensitivity obtained with the development of miniature radio frequency coils used to excite and detect the NMR signals of mass-limited samples.

The application relates to a method for determining beam parameters of a charge carrier beam, a measuring device, and a charge carrier beam device. The charge carrier beam (4) from a charge carrier beam device (1) is guided, by means of a beam deflection unit (3), over a slit aperture arrangement which is provided in an aperture device (7) and which has one or more slit apertures (8). Measurement plane coordinates of the beam components that penetrate the slit aperture arrangement are determined. On the basis of the measurement plane coordinates, the aperture device automatically moves in such a way that a measuring aperture (9) arranged in the aperture device moves over a predefined measurement reference point. The beam parameter is measured by the measuring aperture. In a measuring device (5) suitable for carrying out said method, the slit aperture arrangement has at least two non-parallel slit aperture sections (12, 13, 15, 16) which can be part of a single continuous slit aperture.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: MG-1.10-2015 | Award Amount: 1.80M | Year: 2016

The proposed project, IMAGE, is relevant to Topic MG-1.10-2015, aiming to enhance the EU-China collaborative effort focusing on Innovative methods and numerical technologies for airframe and engine noise reduction. The project consortium consists of 12 partners. The purpose of IMAGE is to investigate experimentally and numerically innovative airframe and engine noise-reduction technologies and, in a systematic conjunction, to develop robust methodologies of addressing these technologies. Airframe noise is addressed by tackling landing gears and high-lift devices, and engine noise through its fan component. Fundamental investigations of three key control strategies are carried out: plasma actuation, turbulence screens and innovative porous materials, on a platform of three configurations, relevant to airframe and aero-engine noise generation and control, including a wing mock-up, tandem cylinder and engine-fan duct. Beyond this, IMAGE explores further the installation effect of aeroacoustic engine-jet/wing interaction with a simplified configuration, as well as low-noise concepts and optimal noise-actuation methods by means of aeroacoustic optimization. The project will conclude a comprehensive understanding of the physical mechanisms concerning flow-induced airframe and engine-fan noise generation, propagation and control, and of further improvement of beam-forming technology and noise source identification in aero-acoustic experimental analysis. The experiment will generate well-documented database, supporting the development of numerical modelling and simulation methodologies for reliable validation and verification. To this end, with technical synthesis and industrial assessment, the noise control methods will be optimized and be facilitated towards potential industrial use, and the methodologies developed should form a robust part of advanced tools in industrial practice.

ASML Netherlands B.V. and RWTH Aachen | Date: 2016-03-24

A lithographic manufacturing system produces periodic structures with feature sizes less than 10 nm and a direction of periodicity (D). A beam of radiation (1904) having a range of wavelengths in the EUV spectrum (1-100 nm or 1-150 nm) is focused into a spot (S) of around 5 m diameter. Reflected radiation (1908) is broken into a spectrum (1910) which is captured (1913) to obtain a target spectrum signal (ST). A reference spectrum is detected (1914) to obtain a reference spectrum signal (SR). Optionally a detector (1950) is provided to obtain a further spectrum signal (SF) using radiation diffracted at first order by the grating structure of the target. The angle of incidence () and azimuthal angle () are adjustable. The signals (ST, SR, SF) obtained at one or more angles are used to calculate measured properties of the target, for example CD and overlay.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2013.3.2 | Award Amount: 4.75M | Year: 2013

Big Data requires Big Pipes. Driven by mobile devices, cloud computing and machine-to-machine Internet, the amount of data processed by data centres continues to grow with a steep progression. Ongoing trends in server virtualisation and green computing morph the data centre architecture and place increasing constraints on the interconnect technology. To meet the need for increased bandwidth, transceiver compactness, reduced power consumption and cost effectiveness for the next generation of data centre and campus-wide communications systems, we are going to develop Broadband Integrated and Green Photonic Interconnects for High-Performance Computing and Enterprise Systems (BIG PIPES). BIG PIPES will reach the industry target of 400 Gbps transceiver modules with a highly integrated technology aiming at aggressively extending the limits of compactness, power consumption (below 30mW/Gbps) and cost-effectiveness, with the objective of providing an optical engine for future 12x25 Gbps CXP and 16x25 Gbps CFP4 modules. To deconstrain the switch board architecture, we will package these optical engines in mid-board optical modules. High campus-wide data throughput is expected to be pivotal in supporting growing data-centre dimensions, as well as modularity in data centre architectures. To enable ultra-broadband transceivers optimally utilising a single integrated light source, we will develop spectrally efficient links reaching 1 Tbps and above. The developed communication system technologies will leverage integrated, mode-locked comb sources to allow both compactness and novel system architectures. The research project will comprise the development of tailored comb sources, the exploration of novel system architectures, as well as the development of photonic devices and assembly technologies enabling system integration. A research intensive SME and the market leader in the high performance InfiniBand segment will keep the project focused on an industrial roadmap.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2009.3.6 | Award Amount: 3.88M | Year: 2010

The current trend in computing architectures is to replace complex superscalar architectures with small homogeneous processing units connected by an on-chip network. This trend is mostly dictated by inherent silicon technology frontiers, which are getting as closer as the process densities levels increase. The number of cores to be integrated in a single chip is expected to rapidly increase in the coming years, moving from multi-core to many-core architectures. This trend will require a global rethinking of software and hardware design approaches.\nThis class of computing systems (Many-core Computing Fabric) promises to increase performance, scalability and flexibility if appropriate design and programming methodologies will be defined to exploit the high degree of parallelism exposed by the architecture. Other potential benefits of Many-core Computing Fabric include energy efficiency, improved silicon yield, and accounting for local process variations. To exploit these potential benefits, effective run-time power and resource management techniques are needed. With respect to conventional computing architectures, Many-core Computing Fabric offers some customisation capabilities to extend and/or configure at run-time the architectural template to address a variable workload.\nThe 2PARMA project aims at overcoming the lack of parallel programming models and run-time resource management techniques to exploit the features of many-core processor architectures. To this purpose, a proper Consortium has been set up to gather the required expertise in the areas of system/application software and computing architectures.The 2PARMA project focuses on the definition of a parallel programming model combining component-based and single-instruction multiple-thread approaches, instruction set virtualisation based on portable bytecode, run-time resource management policies and mechanisms as well as design space exploration methodologies for Many-core Computing Fabrics.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.2.1 | Award Amount: 4.26M | Year: 2013

SPENCER will break new ground for cognitive systems in populated environments. While there is an increasing focus on making robots more socially aware, related approaches are still limited in their capacity to perceive, model and learn human social behavior and respond with appropriate actions in real-time from mobile platforms. SPENCER will systematically address these problems and advance the fields of perception of individual humans and groups, normative human behavior learning and modeling, socially-aware mapping, and socially-aware task, motion and interaction planning under real-world conditions. In particular, by addressing these problems simultaneously in a multi-disciplinary project team, we will exploit synergies which will enable us to design cognitive systems that reach new levels of autonomy, efficiency, robustness, and safety in populated environments, optimizing the trade-off between objective and subjective performance measures. The project is motivated by an end-user market-pull and a technology-push. End-users seek innovative solutions to guide people and efficient mobile information provision. Robotics research meanwhile, has become suitably advanced to start considering humans as more than objects but as people with relationships, social rules and culturally diverse backgrounds. To this end, SPENCER will combine robotics research with social signal processing and socio-psychological user studies that will guide the learning process of socially normative robot behaviors into the relevant directions. The SPENCER consortium includes a large European airline as end-user that will deploy the SPENCER robotic demonstrator for the purpose of smart flow management of transfer passengers at the Amsterdam Schiphol Airport. This deployment has a large exploitation potential and is an excellent benchmark of the research developed in SPENCER given the demanding nature of airports as highly populated real-world environments.

Agency: European Commission | Branch: FP7 | Program: CP | Phase: ICT-2011.4.2 | Award Amount: 10.37M | Year: 2012

Today Europe is facing larger and more critical language challenges than ever before. The production of multilingual content now far outpaces our ability to translate it by human effort and we must turn to automatic methods to cope. Thus, effective and innovative alternatives must be provided to Europes citizens and businesses. High performing machine translation technology can be part of the solution.\nRecent advances in machine translation (MT) technology now show great promise, as systems can be trained automatically from data and achieve respectable performance, even from speech input. However, MT still has very high maintenance costs, and is unsuited to cope with many of todays digital medias relentlessly changing streams of information, across different topics, styles, and genres.\nBridges Across the Language Divide (EU-BRIDGE) proposes to advance speech translation to the point where it can deal with the varying input conditions occurring in digital media, and is able to automatically adapt itself to the changing domains.\nTraining data for modern state-of-the-art statistical speech translation models has become a valuable resource that is difficult and expensive to collect in sufficient quantities for all languages and domains of interest. EU-BRIDGE will therefore seek to reduce the cost of data collection and the dependency on collected data.\nIn its research EU-BRIDGE will address European and non-European languages of high importance to the businesses and citizens of Europe, also dealing with the problem of addressing under-resourced languages and their specific peculiarities.\nEU-BRIDGE will further be working on European infrastructure and network services in order to provide European businesses with a tangible benefit when operating in a multilingual market, e.g. TV captioning and translation. EU-BRIDGE has identified four use cases which will be serviced by its infrastructure and which will proof the concept of EU-BRIDGE to stimulate use by many more use case developers in the future.

Agency: European Commission | Branch: FP7 | Program: JTI-CS | Phase: JTI-CS-2011-3-SFWA-02-019 | Award Amount: 799.12K | Year: 2013

The BirdStrike project aims to establish a validated bird strike analysis capability, which enables the SFWA partners to simulate bird impact on a CFRP leading edge for a NLF wing. This will be achieved by setting up a combined program of test and analysis to determine the extent of damage and criteria to be applied to analyses of leading edge panels for NLF wings. The main scientific and technical work comprises six main research objectives in agreement to the present Call for Proposals (CfP) topic: 1) Analysis of bird strikes on flat and representative curved panels at various angles of impact, using an existing bird impact model that will be provided by the SFWA Partners. 2) Design and analysis of a supporting frame for bird-strike impact tests on flat and representative curved panels. 3) Manufacturing of an agreed number of flat and representative curved panels that include supporting stringers, sparcaps or other structural features. 4) Completion of impact tests at various angles. 5) Validation of analyses and numerical models. 6) Delivery of a tool that can predict the extent of damage in a representative Composite LE geometry.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-17-2014 | Award Amount: 4.00M | Year: 2015

A European Digital Single Market free of barriers, including language barriers, is a stated EU objective to be achieved by 2020. The findings of the META-NET Language White Papers show that currently only 3 of the EU-27 languages enjoy moderate to good support by our machine translation technologies, with either weak (at best fragmentary) or no support for the vast majority of the EU-27 languages. This lack is a key obstacle impeding the free flow of people, information and trade in the European Digital Single Market. Many of the languages not supported by our current technologies show common traits: they are morphologically complex, with free and diverse word order. Often there are not enough training resources and/or processing tools. Together this results in drastic drops in translation quality. The combined challenges of linguistic phenomena and resource scenarios have created a large and under-explored grey area in the language technology map of European languages. Combining support from key stakeholders, QT21 addresses this grey area developing (1) substantially improved statistical and machine-learning based translation models for challenging languages and resource scenarios, (2) improved evaluation and continuous learning from mistakes, guided by a systematic analysis of quality barriers, informed by human translators, (3) all with a strong focus on scalability, to ensure that learning and decoding with these models is efficient and that reliance on data (annotated or not) is minimised. To continuously measure progress, and to provide a platform for sharing and collaboration (QT21 internally and beyond), the project revolves around a series of Shared Tasks, for maximum impact co-organised with WMT. To support early technology transfer, QT21 proposes a Technology Bridge linking ICT-17(a) and (b) projects and opening up the possibility of showing technical feasibility of early research outputs in near to operational environments.

Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: AAT.2011.6.3-2. | Award Amount: 3.29M | Year: 2011

The future air transport system will be confronted with new challenges: it must be safer, greener and more effective than the current system. There will be more global industrial competition and fossil fuel reserves will diminish leading to increased fuel prices. New radical ideas, methods and technologies are needed to respond to these challenges and to keep Europe world leader in aviation. One of the ideas that came from the Out of the Box project was to launch and recover aircraft by using ground-based power. Several ideas were proposed like using microwave power technology, hoisting aircraft in the air, aircraft carriers type of aircraft launch and recovery etc. The GABRIEL proposal is based on a system using magnetic levitation technology to enable aircraft take-off and landing. This unique solution will reduce aircraft fuel consumption since aircraft weight can be reduced as no undercarriage will be needed, less fuel needs to be carried onboard and engines can be smaller as less thrust is needed. Using ground power will also reduce CO2 and NOx emissions at airports whilst noise levels can be substantially reduced since only airframe noise will be produced during take-off. Airport capacity can be increased by introducing multiple launch and recovery ramps thus alleviating the problem of limited runway capacity in Europe. Gabriel will investigate if such a system is feasible and cost effective. Magnetic levitation is already a developed and deployed technology in rail transportation. However, research is needed to prove the technical feasibility of the concept in air transportation. GABRIEL will investigate how to adapt the existing magnetic levitation technology and to redesign the aircraft and more particularly its fuselage. The project will also study the feasibility of launch and recovery in connection to operating limits and aircraft flight controls. Operational and safety issues will be studied extensively. A small scale test will be designed to validate, assess the feasibility and estimate the limits of the assisted take-off and landing concept. The issue of emergency landings will be addressed. The project will also perform an extensive cost benefit analysis, covering the effects on fuel savings, environmental benefits, new airport infrastructures and the required power supply. The GABRIEL is a typical out of the box project that involves 12 partners from 7 European countries. The project will last for 36 months.

Agency: European Commission | Branch: FP7 | Program: MC-ITN | Phase: FP7-PEOPLE-2011-ITN | Award Amount: 4.21M | Year: 2012

The proposed project COPA-GT has been structured to provide training of a multi-disciplinary and intersectorial nature for young Fellows in Europe in the field of propulsion and electric power generation systems. The young researchers will obtain expertise in gas turbines engine (GT) design, based on fluid and structural mechanics, combustion, acoustics and heat transfer. They will become familiar with tools to design and operate innovative GT engines, taking into account the whole diversity of physics involved, in a consistent and integrated way, to improve the system performances and reliability, adapt them to future sustainable fuels and operation conditions, and lower their environmental impact. This implies a strong expertise in High Performance Computing (HPC) and physics, for the use of the most advanced numerical simulation tools, that are run on the most powerful computers. What is new and original in this project, is that the Fellows will be trained on the integrated engine design, taking into account component performance and interaction. Untill now all training and design was focused on individual components, postponing component interaction till commissioning of the engine, which has led to severe delays and difficulties in changing operating conditions in the past. With the advanced hard and software tools available at the partners institutions the young researchers will be able to develop an integrated engine performance prediction.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-07-2014 | Award Amount: 6.94M | Year: 2015

The SSICLOPS project will focus on techniques for the management of federated private cloud infrastructures, in particular cloud networking techniques (within software-defined data centres and across wide-area networks). Key deliverables from the project will include a meta data description language for workloads, resources and policies, a flexible scheduling system using meta data, workload-specific adaptations to TCP/IP stacks, and data center performance analysis tools. Addressing topics, such as dynamic configuration, automated provisioning and orchestration of cloud resources the SSICLOPS projects will investigate high-performance, vertically integrated network stacks for intra/inter-cloud communication and efficient, scalable, and secure intra/inter-DC and client-facing transport mechanisms. The project will design, implement, demonstrate, and evaluate three specific use cases, namely a cloud-based in-memory database, the analysis of physics experiment data, and the prototypical extension of network stacks for a telecom provider in the SSICLOPS testbed.

Agency: European Commission | Branch: H2020 | Program: IA | Phase: LCE-08-2014 | Award Amount: 13.14M | Year: 2015

Integration of distributed small/medium size storage systems can allow operating distribution grids much more flexibly, thus realizing smart grid features like local demand-supply balancing, congestion relief, peak shaving and effective RES integration. However, few technologically mature decentralized storage systems are commercially available today at affordable prices, while both viable business models and the underlying legal and regulatory framework are lagging behind. As an answer ELSA will implement and demonstrate an innovative solution integrating low-cost second-life Li-ion batteries and other direct and indirect storage options, including heat storage, demand-side management, as well as use of intermittent RES. The core idea is to consider Storage as a Service towards building and district managers for local energy management optimization, and towards DSO for enhanced network operations. ELSA will adapt, build upon, and integrate close-to-mature (TRL>=5) storage technologies and related ICT-based energy management systems for the management and control of local loads, generation and single or aggregated real or virtual storage resources, including demand response, in buildings, districts and distribution grids. Data models ensuring interoperability among building, districts and DSOs and novel business models enabled by energy storage as-a-service will be developed. Different configurations will be demonstrated along six test sites, where a set of different storage technologies will be integrated. Safety issues and social acceptance will be dealt with by communication and product reliability demonstration. A technical, economic and environmental validation, involving relevant stakeholders, will be carried out to nurture the European-wide replication of the ELSA concept, prepare the ground for a concrete roll out of the resulting TRL9 technologies and provide input for regulatory framework adaptation.

Agency: European Commission | Branch: FP7 | Program: BSG-SME | Phase: SME-1 | Award Amount: 1.48M | Year: 2011

European SMEs which produce high precision parts by means of hard turning are facing a steady loss of competitiveness in their growing markets since existing manufacturing technologies do not fulfil increasing demands on part quality and variety. During the last years the competition has worsen due to up-coming low wages countries outside Europe and an increasing cost pressure. Additionally these days the economic crisis causes a tremendous drop in orders. To sustainably ensure the survival and competitiveness of the SMEs a technology must be provided which enables a faster part-production with concomitantly better part-qualities. This technology has to consist of an automated production system integrated in one lathe which ensures a reliable flexible production of high-precision parts of hardened steel. To achieve this goal, the development of several components to be merged into an innovative production system for the reliable production of high-precision parts of hardened steel by means of the combined process of hard turning and polishing is obligatory. These components will encompass the following: - a new developed monitoring system will detect and avoid the generation of undesirable surface defects like so called white layers. - an optical measurement device will calibrate a new tool directly and measure the cutting edge geometry and wear of the tool in order to compensate form errors in conjunction with the controlling of the lathe - the system will be completed by a polishing device to be able to produce up to optical surface qualities. To reach the envisaged high-level efficiency of the production system concerning the quality and production times the process strategy of the combined process of hard turning and polishing will be developed. Thus the easiTAP system enables the SMEs to a reliable production and a drastic reduction of non-productive times and thus to a significant increase of their productivity.

Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: SST-2007-4.1-04 | Award Amount: 466.45K | Year: 2009

In 2005, around 41,600 people were killed and more than 1.7 million injured in European road accidents. Although the number of road fatalities has declined by more than 17% since 2001, greater efforts will have to be made if the European Commissions target of halving the number of deaths on the roads by 2010 is to be met. To realise the targets for road safety in the future, stakeholders indicate the necessity of integrating research capacities currently existing or emerging as far as possible. For this purpose the general objectives of COVER are to develop a harmonised and consistent direction of research and to accelerate the implementation of research findings of four complementary EU and US initiatives dealing with road and, in particular, vehicle safety. To maximise the benefits gained from the individual initiatives synergies between the projects will be fully exploited by coordinating the exchange and usage of results, joining dissemination actions towards relevant stakeholders, and exchanging of best practices and policies with respect to relevant aspects like test methods and deployment strategies. For the objective of dissemination both towards relevant high-level stakeholders and the general public a coordinated approach will be an important factor in providing a clear message and obtaining the necessary visibility. This visibility of research results will be the precondition of the effective deployment in vehicle safety products and enhanced test and evaluation methods Subsequently, COVER brings together coordinators of three FP7 and, relevant for harmonisation with the US, one USDOT initiative. Together with partners from the participating projects the coordinators identified joined research activities needed to enable the introduction of new vehicle safety technologies and related test and evaluation methods in an efficient (cost and time) manner.