New Brunswick, NJ, United States
New Brunswick, NJ, United States

Rutgers, The State University of New Jersey, , commonly referred to as Rutgers University, Rutgers, or RU, is an American public research university and the largest institution for higher education in New Jersey.Originally chartered as Queen's College on November 10, 1766, Rutgers is the eighth-oldest college in the United States and one of the nine "Colonial Colleges" founded before the American Revolution. The college was renamed Rutgers College in 1825 in honor of Colonel Henry Rutgers , a New York City landowner, philanthropist and former military officer, whose generous donation to the school allowed it to reopen after years of financial difficulty. For most of its existence, Rutgers was a private liberal arts college affiliated with the Dutch Reformed Church and admitted only male students. The college expanded its role in research and instruction in agriculture, engineering, and science when it was named as the state's sole land-grant college in 1864 under the Morrill Act of 1862. It gained university status in 1924 with the introduction of graduate education and further expansion. However, Rutgers evolved into a coeducational public research university after being designated "The State University of New Jersey" by the New Jersey Legislature in laws enacted in 1945 and 1956. It is one of only two colonial colleges that later became public universities.Rutgers has three campuses located throughout New Jersey. The New Brunswick campus straddles the Raritan River in New Brunswick and adjacent Piscataway. Two regional campuses are located in Newark and Camden, with additional facilities elsewhere in New Jersey. Instruction is offered by 9,000 faculty members in 175 academic departments to over 45,000 undergraduate students and more than 20,000 graduate and professional students.Rutgers is considered to be a Public Ivy, a term coined to describe public universities that offer an academic climate comparable to that in the Ivy League. The University is accredited by the Middle States Association of Colleges and Schools and is a member of the Committee on Institutional Cooperation, the Association of American Universities and the Universities Research Association Wikipedia.


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Patent
Princeton University and Rutgers University | Date: 2016-08-22

The American Cancer Society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the United States of which 219,440 would be lung and bronchus related. The standard treatments for NSCLC include surgery, chemotherapy, radiation, laser and photodynamic therapy, all with various success rates depending on the stage of the cancer. National Cancer Institute assesses, however, that results of standard treatment are generally poor with only a 15 percent 5-year survival rate for combined cancer stages. Challenges facing the current chemotherapy drugs include excessive toxicity to healthy tissues and limited ability to prevent metastases. A dual drug delivery system described herein selectively targets the lung to deliver anti-cancer drugs and inhibit the formation of metastases.


Patent
Rutgers University | Date: 2016-08-15

The invention provides bipartite inhibitors of bacterial RNA polymerase having the general structural formula (I): X--Y(I) wherein X is an moiety that binds to the rifamycin binding site of a bacterial RNA polymerase, Y is a moiety that binds to the GE23077 binding site of a bacterial RNA polymerase, and is a linker. The invention also provides compositions comprising such compounds, methods of making such compounds, and methods of using said compounds. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy.


A bonding element, a bonding element matrix and composite materials with a wide range of attractive properties that may be optimized, including, but not limited to, mechanical properties, thermal properties, magnetic properties, optical properties and nuclear properties, as a result of a first layer and second layer structure or core, first layer, and second layer structure of the bonding elements, as well as methods for making the bonding elements and the corresponding ceramic and/or composite materials.


Patent
Rutgers University and Lehigh University | Date: 2016-10-26

Augmented or synergized anti-inflammatory constructs are disclosed including anti-inflammatory amino acids covalently conjugated with other anti-inflammatory molecules such as nonsteroidal anti-inflammatory drugs, vanilloids and ketone bodies. Further conjugation with a choline bioisostere or an additional anti-inflammatory moiety further augments the anti-inflammatory activity.


Patent
Rutgers University | Date: 2016-05-31

Recombinant bacterial triple-helical collagen-like proteins comprising two or more repetitive sequences of Gly-Xaa-Yaa yielding high-stability polymeric constructs without the need for post-translational modifications and which may incorporate one or more functional domains of biological or structural importance. The polymers are capable of high-yield production for a variety of applications


The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.


Patent
Rutgers University | Date: 2016-10-19

Bone tissue materials comprising insulin-mimetic agents, such as suitable zinc, vanadium, tungsten, molybdenum, niobium, selenium, and manganese compounds, for facilitating spinal fusion of vertebrae M spinal fusion surgical procedures, and methods thereof. Additionally provided is a bone tissue kit for facilitating fusion of vertebrae in a spinal fusion surgical procedure including a composition formulated for facile application in a spinal fusion procedure comprising an insulin-mimetic agent and a pharmaceutically acceptable carrier. Yet further provided is an implantable device for enhancing spinal fusion including a prosthetic implant configured to stabilize and promote the fusion of two adjacent vertebrae, wherein the bone tissue contacting surfaces of the prosthetic implant are coated with a composition comprising an insulin-mimetic agent.


Patent
Rutgers University | Date: 2017-02-22

The present invention provides a probe set for in situ hybridization that enables detection of individual mRNA molecules. The present invention also provides a kit or a hybridization solution comprising a probe of the invention and a method of detecting a first target sequence of individual mRNA molecules in a cell.


A comprehensive overview of advances in the synthesis of organoborane polymers for optical, electronic, and sensory applications, is presented. Study of conjugated main chain organoboron polymers obtained through hydroboration of 2,5-diethynylthiophene derivatives with BCl3/Et3SiH mixture showed that polymers are differently colored depending on the substituents on the alkynyl groups. Luminescent polymer gels prepared by hydroboration polymerization of MesBH2 showed the occurrence of partial gelation when the reaction is performed in relatively concentrated THF solution. Tin-boron exchange reactions are also studied as a potentially milder and more selective polymerization method showing that the polycondensation process occurs between a bifunctional haloborane and a ditin species.


Sellwood J.A.,Rutgers University
Reviews of Modern Physics | Year: 2014

Disk galaxies evolve over time through processes that may rearrange both the radial mass profile and the metallicity distribution within the disk. This review of such slow changes is largely, though not entirely, restricted to internally driven processes that can be distinguished from evolution driven by galaxy interactions. It both describes our current understanding of disk evolution and identifies areas where more work is needed. Stellar disks are heated through spiral scattering, which increases random motion components in the plane, while molecular clouds redirect some fraction of the random energy into vertical motion. The recently discovered process of radial migration at the corotation resonance of a transient spiral mode does not alter the underlying structure of the disk, since it neither heats the disk nor causes it to spread, but it does have a profound effect on the expected distribution of metallicities among the disk stars. Bars in disks are believed to be major drivers of secular evolution through interactions with the outer disk and with the halo. Once the material that makes up galaxy disks is converted into stars, their overall angular momentum distribution cannot change by much, but that of the gas is generally far more liable to rearrangement, allowing rings and pseudobulges to form. While simulations are powerful tools from which we have learned a great deal, those of disks may suffer from collisional relaxation that requires some results to be interpreted with caution. © 2014 American Physical Society.

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