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Kharchenko V.P.,Russian Center for Roentgeno Radiology Research | Panshin G.A.,Russian Center for Roentgeno Radiology Research | Gvarishvili A.A.,Russian Center for Roentgeno Radiology Research
Voprosy Onkologii | Year: 2011

Our study was conducted in patients with primary squamous cell carcinoma of the trachea and adenoid cystic carcinoma (191) (radical surgery - 90; combined treatment - 101). The former pathology was relatively more aggressive. Combined treatment proved more effective as compared with surgery alone (5- and 10-year survival after surgery was 79 and 64%; combined treatment - 92 and 79%, respectively). Source


Kharchenko V.P.,Russian Center for Roentgeno Radiology Research | Chkhikvadze V.L.,Russian Center for Roentgeno Radiology Research | Sdvizhkov A.M.,Russian Center for Roentgeno Radiology Research
Voprosy Onkologii | Year: 2010

The paper deals with immediate and end results of surgical treatment of 435 elderly patients (70 years old and more) with gastric cancer and peculiarities of postoperative complications and outcome influencing the postoperative course of the disease. Metastasis to the regional lymph nodes appeared to be a prognostic factor of crucial importance in the latter period: 5-year recurrence-free (N0) survival was 60.3%±5.2 vs. 17.6%±10.3 (in 1-6 lymph nodes) and 5.2%±5.0 (in 7-15 lymph nodes) (N1). Source


Izmilov T.R.,Russian Center for Roentgeno Radiology Research | Panshin G.A.,Russian Center for Roentgeno Radiology Research | Datsenko P.V.,Russian Center for Roentgeno Radiology Research
Voprosy Onkologii | Year: 2010

Data on the treatment of 278 patients with brain tumors grade III-IV were evaluated, end-results compared and relevant prognostic factors identified. On our view, average fractionated radiotherapy is not inferior to standard fractionation modalities. It offers an advantage of using different single target doses. In primary patients with high-grade malignancies, an index (Karnofsky) of less than 60% appeared to be the most significant practical factor of prognosis. Both age and tumor size proved significant. Source


Datsenko P.V.,Russian Center for Roentgeno Radiology Research | Podolsky P.N.,Russian Center for Roentgeno Radiology Research | Panshin G.A.,Russian Center for Roentgeno Radiology Research | Sotnikov V.M.,Russian Center for Roentgeno Radiology Research | Bozhenko V.K.,Russian Center for Roentgeno Radiology Research
Voprosy Onkologii | Year: 2010

Basic hematological features of CEA/ABVD medication for Hodgkin's disease were studied. An effective model was worked out on the principle of data discrimination for predicting different leukocytic toxicities induced by cytostatics-1 administration, once in two weeks. It might predict individual limits (dosage and intervals) of a chemotherapy course unless a colony-stimulation technique is used. Source


Kaprin A.D.,Russian Center for Roentgeno Radiology Research | Pavlov A.Yu.,Russian Center for Roentgeno Radiology Research | Ivanov S.A.,Russian Center for Roentgeno Radiology Research | Gafanov R.A.,Russian Center for Roentgeno Radiology Research
Voprosy Onkologii | Year: 2011

Despite its side-effects, most of which are reversible, efficiency of hormonal therapy of prostate cancer has been demonstrated. Advantages of intermittent hormonal therapy have been evaluated in a number of phase II clinical tests. As a result, side-effects were shown to decrease and quality of life improved. Preliminary phase III tests failed to detect any negative effect of intermittent hormonal therapy on tumor progression-free survival as compared with continuous hormonal therapy. Source

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