GM Global Technology Operations LLC, Bilik and Russian Academy of Sciences | Date: 2017-05-10
Methods and systems for a vehicle cognitive radar are provided. The system includes a transmitter is configured to transmit a first plurality of transmittal signals for a cognitive radar system of a vehicle, the cognitive radar system having at least a first modality. An interface is configured to receive sensor data from one or more sensors having a second modality that is different from the first modality. A processor is coupled to the interface, and is configured to select an adjusted waveform for a second plurality of transmittal signals for the cognitive radar system using the sensor data.
Goshen, Harel and Russian Academy of Sciences | Date: 2017-03-22
A set for assembling a length and shape adjustable planter comprising (a) a plurality of elongate troughs being length customizable by cutting thereof; the elongate troughs having a longitudinal axis and a -inverted cross section; the elongate troughs interconnectable therebetween; (b) interconnecting members configured for interconnecting the elongate troughs in series; and (c) end members configured for mounting onto a free end of the elongate troughs. A surface of each trough at least partially is provided with a surface profile distributed over a length of the trough. The interconnecting members are securable on the surface profile.
GM Global Technology Operations LLC, Stainvas Olshansky, Bilik and Russian Academy of Sciences | Date: 2017-05-10
Methods and systems are provided for selectively analyzing radar signals of a radar system of a vehicle. A receiver is configured to receive a plurality of radar signals of a radar system of a vehicle. The interface is configured to obtain data from one or more sensors of the vehicle having a modality that is different from the radar system. The processor is coupled to the receiver and to the interface, and is configured to selectively analyze the plurality of radar signals based upon the data.
News Article | May 10, 2017
A new generation of higher-powered batteries for phones and cameras could result from ground-breaking research led by scientists at the University of Kent. Researchers from the University's School of Physical Sciences (SPS), working with scientists from other European institutions, formulated a recipe to increase the rate at which a solid material - an artificial mineral - can conduct charge. The team found that a phenomenon known as geometric frustration can be used in this process to increase the charge transport rate in the solid material in a way that is comparable with heating that material. Making use of this phenomenon, the team was able to 'tune' materials to be used in future batteries and fuel cells to speed up ionic conductivity. Lead researcher Dr Dean Sayle and his team in SPS found that geometric frustration broke up the regimented formation of atoms in the material, leading to a more disordered pattern. This disordered pattern allowed the charge to pass through the material at a much higher rate. Dr Sayle said: 'Disorder can be created by geometric frustration which might be understood as randomly giving two kinds of differently sized umbrellas to a regimented parade of people and telling them to put them up and come as close together as the size of the umbrellas allow. 'Naturally, this will lead to a destruction of the former formation towards a disordered formation exhibiting a large number of gaps. Similarly, we used geometric frustration to make the atoms disordered by mixing two differently sized atoms together which increased charge transport by 100,000'. As well as more powerful batteries, the new technique may lead to the development of new energy materials with zero- emissions. The paper, entitled Is Geometric Frustration-Induced Disorder a Recipe for High Ionic Conductivity? (Dean Sayle, Andre Duvel, Alan Chadwick, David Pickup, Silvia Ramos, Lewis Sayle, Emma Sayle, Thi Sayle, all University of Kent; Paul Heitjans, Leibniz Universita?t Hannover Germany; Pavel Fedorov, General Physics Institute of Russian Academy of Sciences, Russia; Gudrun Scholz, Humboldt-Universita?t zu Berlin Germany; Giannantonio Cibin, Diamond Light Source UK) is published in the Journal of the American Chemical Society. See: http://pubs. For further information and image requests contact Martin Herrema at the University of Kent Press Office. News releases can also be found at http://www. Established in 1965, the University of Kent - the UK's European university - now has almost 20,000 students across campuses or study centres at Canterbury, Medway, Tonbridge, Brussels, Paris, Athens and Rome. It has been ranked: third for overall student satisfaction in the 2014 National Student Survey; 16th in the Guardian University Guide 2016; 23rd in the Times and Sunday Times University Guide 2016; and 22nd in the Complete University Guide 2015. In the Times Higher Education (THE) World University Rankings 2015-16, Kent is in the top 10% of the world's leading universities for international outlook and 66th in its table of the most international universities in the world. The THE also ranked the University as 20th in its 'Table of Tables' 2016. Kent is ranked 17th in the UK for research intensity (REF 2014). It has world-leading research in all subjects and 97% of its research is deemed by the REF to be of international quality. Along with the universities of East Anglia and Essex, Kent is a member of the Eastern Arc Research Consortium. The University is worth £0.7 billion to the economy of the south east and supports more than 7,800 jobs in the region. Student off-campus spend contributes £293.3m and 2,532 full-time-equivalent jobs to those totals. In 2014, Kent received its second Queen's Anniversary Prize for Higher and Further Education.
News Article | May 10, 2017
LAFAYETTE, IN, May 10, 2017-- William Leon McBride is a celebrated Marquis Who's Who biographee. As in all Marquis Who's Who biographical volumes, individuals profiled are selected on the basis of current reference value. Factors such as position, noteworthy accomplishments, visibility, and prominence in a field are all taken into account during the selection process.Marquis Who's Who, the world's premier publisher of biographical profiles, is proud to name Dr. McBride a Lifetime Achiever. An accomplished listee, Dr. McBride celebrates many years' experience in his professional network, and has been noted for achievements, leadership qualities, and the credentials and successes he has accrued in his field.A respected and long-standing figure in his industry, Dr. McBride most recently served as the Arthur G. Hansen Distinguished Professor for Purdue University, a position he has held since 2001.In addition to his status as Lifetime Achiever, Dr. McBride has previously received the Silver Medal from the Institute of Philosophy at the Russian Academy of Sciences, and has been recognized as a Decorated Chevalier of the Ordre des Palmes Academiques. Furthermore, Dr. McBride has been a featured listee in Who's Who in America, Who's Who in American Education, Who's Who in the Midwest and Who's Who in the World.About Marquis Who's Who :Since 1899, when A. N. Marquis printed the First Edition of Who's Who in America , Marquis Who's Who has chronicled the lives of the most accomplished individuals and innovators from every significant field of endeavor, including politics, business, medicine, law, education, art, religion and entertainment. Today, Who's Who in America remains an essential biographical source for thousands of researchers, journalists, librarians and executive search firms around the world. Marquis publications may be visited at the official Marquis Who's Who website at www.marquiswhoswho.com
Russian Academy of Sciences, DuPont Company, Ovchinnikov, Bobkova, Medvinskaya, Samokhin and Nekrasov | Date: 2017-04-19
The present invention relates to the field of genetic engineering and medicine. Proposed is a method for treating neurodegenerative diseases and Alzheimers disease that includes the intranasal administration to a subject of a therapeutically effective amount of the YB-1 protein and/or active fragment and/or derivative thereof.
News Article | May 11, 2017
Members of the Faculty of Biology of the Lomonosov Moscow State University have studied arctic ground squirrels, inhabiting the Indigirka river basin, and found out that their relatives now inhabit Kamchatka. The scientists have shared with the research results in an article, published in Scientific Reports journal. Beringian ground squirrels are model organisms, used by scientists for studies of trans-Beringian connections (namely, connections between the Old and New Worlds, established at existence time of the terrestrial Bering Land Bridge at the site of the Bering Strait). Studies of so called arctic ground squirrels, inhabiting the Indigirka river basin, Urocitellus glacialis, have revealed new data, concerning trans-Beringian connections. This fossil species was described by Boris Vinogradov, a Soviet zoologist. The description was made on the basis of three carcasses, found in 1946 by unnamed prisoners of GULAG in vertical excavations (shafts) at a depth of 12.5 meters. Preservation of the mummified carcasses of ground squirrels was so good that even ectoparasites (lice) were found in their hair. It's a unique case as actually no hair coat is usually preserved. Later on a biologist named Igor Gromov, paid attention to the fact that fossils of Citellus glacialis resemble Beringian ground squirrels, inhabiting Alaska, but not northeastern Asia. It became a step up towards studying the glacialis form with the help of molecular genetic methods. The scientists were interested in conducting this research even in the 90-s, however, lack of any experience of operating with ancient DNA among Russian scientists at that time was a formidable obstacle on this way. The complexity of such DNA sequence lies in the fact that DNA degradates with time as a result of dehydration of carcasses, low temperatures or strong salt content. That's why special processing of ancient DNA before its studying is necessary. Marina Faerman-Arkchangelskaya, who graduated from the Anthropology Department of the Lomonosov Moscow State University, currently working at the Hebrew University of Jerusalem, helped the scientists to solve this problem. She showed the Moscow colleagues how to work with ancient DNA and sequenced cytochrome b gene in the U. glacialis paratype. The substance has been extracted from tissue samples of a ground squirrel, so that one could estimate degree of relationship with present-day representatives, basing on this gene. She also organized dating the sample on the new device - AMS (Accelerator mass spectrometer), started working in Novosibirsk. It allows to date, basing on tissue microsamples, what prevents destroying the sample. In usual devices you need a sample at the rate of 5 grams of carbon, what means a whole skull of a ground squirrel or a dog shoulder bone. Consequently, in cases of small animals you take the larger half of a sample for dating. The analysis results show that the U. glacialis form is three times older than supposed to be - it's 30 000-year-old. The scientists have conducted extraction and sequence of all present-day and another three fossil samples in Russia. The U. Glacialis species has proved to be very near to present-day Beringian ground squirrels (Urocitellus parryii), however, at that moment specialists knew its closest relatives only from the New World, from the Alaska Peninsula. The scientists have also established that Beringian ground squirrels colonized Eurasia at least twice. It was likely connected with glaciation, before which ground squirrels managed to distribute in Asia from America. Later they became extinct in Asia cause of cooling, and after warming a new part of ground squirrels came from Alaska. Nikolai Formozov, a Leading researcher in the Laboratory of Vertebrate Behavior, existing at the Department of Vertebrate Zoology of the Faculty of Biology at the Lomonosov Moscow State University and the article author shares: "In the course of the work we ask ourselves if there are somewhere descendants of the first colonization wave in Eurasia. Kamchatka was the most appropriate region from this point of view but we didn't have substances from there at that time. But suddenly we got unexpected support. Igor Shpilenok, a famous blogger and photographer, was busy with months-long photographic surveying of animals in the Kronotsky Nature Reserve. Once the Moscow researchers reached out to him and asked to assist in gathering tissue samples of ground squirrels, then a fox, named Alisa, inhabited nearby Igor, began to bring ground squirrels to the doorstep of his lodge. Already first samples, gathered by Alisa, precisely proved the hypothesis - ground squirrels from Kamchatka appeared to be close relatives of the glacialis form. The fox was wilde bur quite closely communicated with people and sometimes brought ground squirrels as they are an easy target in that places. Probably, it's a trust mark, like when cats bring caught mice to their masters and get surprised that they are reluctant to eat mice." The scientists notice that their project substantially contributes to understanding trans-Beringian connections and dispersal routes of various animals in the Pleistocene in northeastern Asia. The project has been done in cooperation with the scientists from the Ministry of Healthcare of the Russian Federation; I.D. Papanin Institute for Biology of Inland Water, Russian Academy of Sciences; Institute of Physicochemical and Biological Problems in Soil Science, Russian Academy of Sciences; Zoological Institute, Russian Academy of Sciences; Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Sciences; Diamond and Precious Metals Geology Institute of the Siberian Branch of the Russian Academy of Sciences; Penza State University, Weizmann Institute of Science and Hebrew University of Jerusalem, Israil.
Ugrumov M.V.,Russian Academy of Sciences
Advances in Pharmacology | Year: 2013
In addition to catecholaminergic neurons possessing all the enzymes of catecholamine synthesis and the specific membrane transporters, neurons partly expressing the catecholaminergic phenotype have been found a quarter of a century ago. Most of them express individual enzymes of dopamine (DA) synthesis, tyrosine hydroxylase (TH), or aromatic l-amino acid decarboxylase (AADC), lacking the DA membrane transporter and the vesicular monoamine transporter, type 2. These so-called monoenzymatic neurons are widely distributed throughout the brain in ontogenesis and adulthood being in some brain regions even more numerous than dopaminergic (DA-ergic) neurons. Individual enzymes of DA synthesis are expressed in these neurons continuously or transiently in norm and pathology. It has been proven that monoenzymatic TH neurons and AADC neurons are capable of producing DA in cooperation. It means that l-3,4-dihydroxyphenylalanine ( l-DOPA) synthesized from l-tyrosine in monoenzymatic TH neurons is transported to monoenzymatic AADC neurons for DA synthesis. Such cooperative synthesis of DA is considered as a compensatory reaction under a failure of DA-ergic neurons, for example, in neurodegenerative diseases like hyperprolactinemia and Parkinson's disease. Moreover, l-DOPA, produced in monoenzymatic TH neurons, is assumed to play a role of a neurotransmitter or neuromodulator affecting the target neurons via catecholamine receptors.Thus, numerous widespread neurons expressing individual complementary enzymes of DA synthesis serve to produce DA in cooperation that is a compensatory reaction at failure of DA-ergic neurons. © 2013 Elsevier Inc.
Dykman L.A.,Russian Academy of Sciences |
Khlebtsov N.G.,Russian Academy of Sciences
Chemical Reviews | Year: 2014
Recent progress in understanding how size, shape, and surface properties of gold nanoparticles (GNPs) affect their uptake and intracellular fate is studied. The selective penetration of GNPs into cancer and immune cells and the interaction of GNPs with immune cell receptors is also studied. The cellular uptake of spherical GNPs is a receptor-mediated process, the effectiveness of which depends on the size of particles and on the density of ligand coating. Most experimental data accrued for colloidal gold particles confirm the existence of an optimal diameter range, whereas the specific optimal size for uptake may depend on cell type. With an increase in the particle aspect ratio, the effectiveness of GNP uptake into cells decreases; the exocytosis time may also decrease. GNP uptake into cells of the immune system activates the production of pro-inflammatory cytokines, a finding that indicates directly that GNPs are immunostimulatory.
Dykman L.,Russian Academy of Sciences |
Khlebtsov N.,Chernyshevsky Saratov State University
Chemical Society Reviews | Year: 2012
Gold nanoparticles (GNPs) with controlled geometrical, optical, and surface chemical properties are the subject of intensive studies and applications in biology and medicine. To date, the ever increasing diversity of published examples has included genomics and biosensorics, immunoassays and clinical chemistry, photothermolysis of cancer cells and tumors, targeted delivery of drugs and antigens, and optical bioimaging of cells and tissues with state-of-the-art nanophotonic detection systems. This critical review is focused on the application of GNP conjugates to biomedical diagnostics and analytics, photothermal and photodynamic therapies, and delivery of target molecules. Distinct from other published reviews, we present a summary of the immunological properties of GNPs. For each of the above topics, the basic principles, recent advances, and current challenges are discussed. © The Royal Society of Chemistry 2012.