Ruhr University Bochum , located on the southern hills of central Ruhr area Bochum, was founded in 1962 as the first new public university in Germany since World War II. Instruction began in 1965.The Ruhr-University Bochum is one of the largest universities in Germany and part of the Deutsche Forschungsgemeinschaft, the most important German research funding organization.The RUB has been very successful in the Excellence Initiative by the German Federal and State Governments , a competition among Germany's most prestigious universities. It was one of the few institutions left competing for the title of an "elite university", but did not succeed in the last round of the competition. There are currently nine universities in Germany that hold this title.The University of Bochum was one of the first universities in Germany to introduce international Bachelor and Master degrees, which replaced the traditional German Diplom and Magister. Except for a few special cases this process has been completed and all degrees been converted. Today, the university offers a total of 150 different study programs from all fields.Ruhr University is financed and administered by the state of North Rhine-Westphalia. Currently, 38,675 students are enrolled, and the university employs over 5,500 staff , making it one of the ten largest universities in Germany . Kurt Biedenkopf, who later became prime minister of the state of Saxony, was director of the university from 1967 to 1969.Unlike a number of traditional universities, the buildings of Ruhr University are all centralized on one campus, except for the Faculty of Medicine, which also includes some hospitals in Bochum and the Ruhr area. Although the centralized university campus utilizes 1960s architecture almost exclusively, mainly consisting of 14 almost identical high-rise buildings, it is located at the edge of a green belt on high ground adjacent to the Ruhr valley. Wikipedia.
Meier J.J.,Ruhr University Bochum
Nature Reviews Endocrinology | Year: 2012
In healthy humans, the incretin glucagon-like peptide 1 (GLP-1) is secreted after eating and lowers glucose concentrations by augmenting insulin secretion and suppressing glucagon release. Additional effects of GLP-1 include retardation of gastric emptying, suppression of appetite and, potentially, inhibition of β-cell apoptosis. Native GLP-1 is degraded within ∼2-3 min in the circulation; various GLP-1 receptor agonists have, therefore, been developed to provide prolonged in vivo actions. These GLP-1 receptor agonists can be categorized as either short-acting compounds, which provide short-lived receptor activation (such as exenatide and lixisenatide) or as long-acting compounds (for example albiglutide, dulaglutide, exenatide long-acting release, and liraglutide), which activate the GLP-1 receptor continuously at their recommended dose. The pharmacokinetic differences between these drugs lead to important differences in their pharmacodynamic profiles. The short-acting GLP-1 receptor agonists primarily lower postprandial blood glucose levels through inhibition of gastric emptying, whereas the long-acting compounds have a stronger effect on fasting glucose levels, which is mediated predominantly through their insulinotropic and glucagonostatic actions. The adverse effect profiles of these compounds also differ. The individual properties of the various GLP-1 receptor agonists might enable incretin-based treatment of type 2 diabetes mellitus to be tailored to the needs of each patient. © 2012 Macmillan Publishers Limited. All rights reserved. Source
Steinbach I.,Ruhr University Bochum
Annual Review of Materials Research | Year: 2013
This review presents a phase-field model that is generally applicable to homogeneous and heterogeneous systems at the mesoscopic scale. Reviewed first are general aspects about first- and second-order phase transitions that need to be considered to understand the theoretical background of a phase field. The mesoscopic model equations are defined by a coarse-graining procedure from a microscopic model in the continuum limit on the atomic scale. Special emphasis is given to the question of how to separate the interface and bulk contributions to the generalized thermodynamic functional, which forms the basis of all phase-field models. Numerical aspects of the discretization are discussed at the lower scale of applicability. The model is applied to spinodal decomposition and ripening in Ag-Cu with realistic thermodynamic and kinetic data from a database. © Copyright © 2013 by Annual Reviews. All rights reserved. Source
Kramer U.,Ruhr University Bochum
Annual Review of Plant Biology | Year: 2010
During the history of life on Earth, tectonic and climatic change repeatedly generated large territories that were virtually devoid of life and exhibited harsh environmental conditions. The ability of a few specialist pioneer plants to colonize such hostile environments was thus of paramount ecological importance for the continuous maintenance of primary production over time. Yet, we know very little about how extreme traits evolve and function in plants. Recent breakthroughs have given first insights into the molecular basis underlying the complex extreme model trait of metal hyperaccumulation and associated metal hypertolerance. This review gives an introduction into the hyperaccumulator research field and its history; provides an overview of hyperaccumulator germplasm; describes the state of the art of our understanding of the physiological, molecular, and genetic basis underlying metal hyperaccumulation and its evolution; and highlights future research needs and opportunities. Copyright © 2010 by Annual Reviews. All rights reserved. Source
Lunze J.,Ruhr University Bochum
IEEE Transactions on Automatic Control | Year: 2012
The task of synchronizing autonomous agents is solved by a networked controller that steers the agents towards a common trajectory. This technical note extends existing analysis and design methods towards sets of linear agents with individual dynamics. A necessary and sufficient synchronization condition is proved and it is shown that the agents can be synchronized by an appropriate networked controller if and only if their dynamics intersect. © 2012 IEEE. Source
Basf and Ruhr University Bochum | Date: 2015-11-20
The present invention relates to a process for preparing at least one sheet silicate comprising Ga and/or Zn, and based thereon, a framework silicate, preferably of the RRO structure type, to the sheet silicate and framework silicate themselves and to the uses of the silicates, especially of the framework silicate, preferably as catalysts.