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Palakkad, India

Malagan M.A.,Vishwanath Katti Institute of Dental science | Biswas P.P.,Royal Dental College | Muddaiah S.,Coorg Institute of Dental science | Reddy R.,Jodhpur Dental College General Hospital | And 4 more authors.
Journal of Clinical and Diagnostic Research | Year: 2014

Aim: To evaluate the rapidity and amount of separation of four different types of separators (i.e. Elastomeric separators, Dumbbell separators, Kesling springs and NEET springs) and also the percentage of loss of these separators. Materials and Methods: The separating effect of 4 different types of separators (i.e. Elastomeric separators, Dumbbell separators, Kesling springs and NEET springs) were assessed for 3 days, and the separated space between molars and premolars were noted separately for three consecutive days. The number and types of lost separators were recorded at the same time. The amount of separation between molars and 2nd premolar in each quadrant was measured separately with a leaf gauge (sensitivity 5/100mm) and noted on each day.Results: Dumbbell separators proved to be the fastest in producing separation and they produced consistently greater amount of separation on all three days. Conclusions: The Dumbbell separator would be ideal for situations where in rapid separation is needed, and also in cases where in the patient comes with the loss of separators. Source

Palukunnu B.,Royal Dental College | Ravindran N.,Sree Narayana institute of medical science
BMJ Case Reports | Year: 2014

Non-extraction treatment has gained popularity for corrections of mild-to-moderate class II malocclusion over the past few decades. The distalization of maxillary molars is of significant value for treatment of cases with minimal arch discrepancy and mild class II molar relation associated with a normal mandibular arch and acceptable profile. This paper describes our experience with a 16-year-old female patient who reported with irregularly placed upper front teeth and unpleasant smile. The patient was diagnosed to have angles class II malocclusion with moderate maxillary anterior crowding, deep bite of 4 mm on a skeletal class II base with an orthognathic maxilla and retrognathic mandible and normal growth pattern. She presented an ideal profile and so molar distalization was planned with the first-class appliance. Molars were distalised by 8 mm on the right and left quadrants and class I molar relation achieved within 4 months. The space gained was utilised effectively to align the arch and establish a class I molar and canine relation. Copyright 2014 BMJ Publishing Group. All rights reserved. Source

Paranjyothi M.V.,Farooquia Dental College | Mukunda A.,Royal Dental College
Journal of Oral and Maxillofacial Pathology | Year: 2013

Clear cell hidradenoma (CCH) is a benign tumor of skin appendage. This lesion is commonly seen on the head, face, extremities and rarely in the oral cavity. The clinical appearance of this lesion is not specific and differential diagnosis from other lesions, both benign and malignant, can only be made after complete removal of the lesion. Histopathology of these lesions is often confused with tumors of salivary glands because of their striking resemblance. In this case of oral CCH, histopathology was an important aid in the diagnosis and hence, CCH should be considered in the differential diagnosis of lesions of the oral cavity. Source

Bastian A.M.,Royal Dental College | Yogesh T.L.,Mahe Institute of Dental science | Kumaraswamy K.L.,Rajiv Gandhi Institute of Dental science | Kumaraswamy K.L.,Farooquia Dental College
Indian Journal of Cancer | Year: 2013

Apoptosis is a process of programmed cell death occurring in multicellular organisms in whom development, maintenance and sculpturing organs and tissues. Taken together, apoptotic processes are of widespread biological significance; being involved in e.g. development, differentiation, proliferation/homoeostasis, regulation and function of the immune system and in the removal of defected harmful cells. Dys regulation of apoptosis can play a primary or secondary role leading to cancer whereas excessive apoptosis contributes to neuro degeneration, autoimmunity, AIDS, and ischemia. Gaining insight into the techniques for detecting apoptotic cells will allow the development of more effective, higher specific and therefore better-tolerable therapeutic approaches. The goal of this review article is to provide a general overview of current knowledge, on the various technical approaches for detecting apoptotic cells. Source

Gilbert G.H.,University of Alabama at Birmingham | Qvist V.,Royal Dental College | Moore S.D.,University of Alabama at Birmingham | Rindal D.B.,HealthPartners Dental Group | And 3 more authors.
Journal of Public Health Dentistry | Year: 2010

Objectives: Effectively addressing regulatory and human participant protection issues with Institutional Review Boards (IRBs, or ethics committees) and grants administration entities is an important component of conducting research in large collaborative networks. A dental practice-based research network called "DPBRN" (http://www.DPBRN.org) comprises dentists in two health maintenance organizations, several universities, seven US states, and three Scandinavian countries. Our objectives are to describe: a) the various human participants and regulatory requirements and solutions for each of DPBRN's five regions; b) their impact on study protocols and implementation; and c) lessons learned from this process. Methods: Following numerous discussions with IRB and grants administrative personnel for each region, some practitioner-investigators are attached to their respective IRBs and contracting entities via sub-contracts between their organizations and the network's administrative site. Others are attached via Individual Investigator Agreements and contractually obligated via Memoranda of Agreement. Results: IRBs approve general operations under one approval, but specific research projects via separate approvals. Various formal IRB and grants administrative agreements have been arranged to customize research to the network context. In some instances, this occurred after feedback from patients and practitioners that lengthy written consent forms impeded research and raised suspicion, instead of decreasing it. Conclusions: Instead of viewing IRBs and institutional administrators as potentially adversarial, customized solutions can be identified by engaging them in collegial discussions that identify common ground within regulatory bounds. Although time-intensive and complex, these solutions improve acceptability of practice-based research to patients, practitioners, and university researchers. © 2009 American Association of Public Health Dentistry. Source

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