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Kuzmin A.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Linde V.,Rostov Scientific Research Institute of Obstetrics and Pediatrics
Gynecological Endocrinology | Year: 2014

Study objective: Tubal factor accounts for 25-30% of cases of female infertility. Laparoscopy "Gold Standard" for tubal evaluation. However, it is known that during the initial infection of the fallopian tube mucosal damage occurs, a condition which plays a decisive role in reproduction. Materials and methods: In this prospective randomized study, 468 infertile women with evidence of fallopian tube disease were included. In this, for 256 patients (group 1) after laparoscopic salpingolysis, salpingostomy we performed an additional step operation transcervical falloposcopy tubal dilatation (TFTD). 212 patients (group 2) produced only laparoscopic salpingolysis, salpingostomy. Results: As a result, TFTD patency of the fallopian tubes for coaxial catheter was restored in 50 (78%) of 64 tubes with bilateral total occlusion, in 238 (93%) of 254 with partial occlusion of the bilateral, in 14 (58%) of 24 total unilateral occlusion and 26 (92%) of 28 with partial unilateral occlusion. Total number of pregnancies for one year in the first group of patients was 152 (59.3%), in the second 57 (27.1%), of which in the first group 147-intrauterine pregnancies (57.4%) and in the second-46 (21.7%). Conclusion: Falloposcopy surgeon provides good opportunities for the diagnosis and treatment of intralumen lesions. Significant increase in the frequency of uterine pregnancy in the case of an additional step-TFTD during salpingolysis, salpingostomy in patients with tubal factor infertility. © 2014 Informa UK Ltd. Source


Narezhnaya E.,Southern Federal University | Krukier I.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Avrutskaya V.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Degtyareva A.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Igumnova E.A.,Southern Federal University
Biomeditsinskaya Khimiya | Year: 2015

The conditions for the identification and determination of Glutamic acid by capillary zone electrophoresis without their preliminary derivatization have been optimized. The effect of concentration of buffer electrolyte and pH on determination of Glutamic acid has been investigated. It is shown that the 5 Mm borate buffer concentration and a pH 9.15 are optimal. Quantitative determination of glutamic acid has been carried out using a linear dependence between the concentration of the analyte and the area of the peak. The accuracy and reproducibility of the determination are confirmed by the method "introduced - found". Glutamic acid has been determined in the placenta homogenate. The duration of analysis doesn't exceed 30 minutes. The results showed a decrease in the level of glutamic acid in cases of pregnancy complicated by placental insufficiency compared with the physiological, and this fact allows to consider the level of glutamic acid as a possible marker of complicated pregnancy. Source


Gudz E.B.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Botasheva T.L.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Radysh I.V.,Peoples Friendship University of Russia | Avrutskaya V.V.,Rostov Scientific Research Institute of Obstetrics and Pediatrics
Human Ecology | Year: 2012

The article presents the characteristics of the daily cycle "wake-sleep" in women with physiological pregnancy and the risk of interruption. Significant differences in the sleep structure in normal and abnormal pregnancy have been established. It has been detected that changes in nocturnal sleep in abnormal pregnancies were characterized by reduced quantity and increased duration of the sleep cycles, multiple segmentation of sleep phases, lots of awakenings, and increased motor activity during sleep, increased number of apnea compared to normal pregnancy. Source


Pogorelova T.N.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Linde V.A.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Gunko V.O.,Rostov Scientific Research Institute of Obstetrics and Pediatrics | Selyutina S.N.,Rostov Scientific Research Institute of Obstetrics and Pediatrics
Biomedit︠s︡inskai︠a︡ khimii︠a︡ | Year: 2016

The levels of zinc, copper, iron, and magnesium ions, and some of their binding proteins have been investigated in an amniotic fluid under the fetal growth retardation (FGR). FGR, developed under conditions of placental insufficiency, is characterized by a decrease in the content of zinc, iron, and magnesium ions and by an increase in the copper content in the amniotic fluid in the II and III trimesters of pregnancy. During these trimesters the levels of ceruloplasmin, ferritin, and Ca2+,Mg2+-ATPase were lower in FGR, while the level of zinc-a-2-glycoprotein was higher than during the same periods of normal pregnancy. Changes in the parameters studied in the amniotic fluid were associated with developmental disorders of the newborns. These changes obviously have a pathogenetic importance in the development of FGR, and the levels of metal ions and their ratio in the amniotic fluid can be used as markers of the pre- and postnatal pathology.Abstract available from the publisher. Source

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