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News Article | November 17, 2016

Boulder-based Room 214, a digital and social media marketing agency, announced that it was named one of the 2016 Best Places to Work in the country by Outside Magazine. Some of the attributes Outside Magazine highlighted are Room 214’s creative culture and an emphasis on a work-life balance. Room 214 offers unlimited paid days off, a dog-friendly office and weekly in-house activities ranging from happy hours to fun runs. It also offers profit sharing and 401(k) matching. Staff members recently improved on an employee incentive program that includes progressive recruitment bonuses and paid, in-state vacations after employees hit their 5-year anniversary with the agency. “This kind of recognition is on everyone in the agency,” said Room 214 Co-founder Jason Cormier. “When people can lead with humility, are really interested in doing their best work, and are acting out of love instead of fear -- well, that’s going to be a great place to work.” Room 214 values giving back, with its time, talent and treasure. In addition to its pro-bono work on behalf of nonprofits, the company hosts regular fundraisers, food drives and volunteer events involving the entire company. “This year’s list of Best Places to Work highlights employers who go above and beyond for their staff,” said Outside Online Editor Scott Rosenfield. “Included are organizations that emphasize a healthy work-life balance and promote, encourage and reward employees to live active and healthier lives.” The agency practices a unique model of open book management, offering complete financial transparency -- and a means for everyone (from intern to partner) to contribute to the company’s vision and success. In addition to Outside Magazine’s published list, Room 214 also just announced its inclusion as one of the Top 250 Private Companies in Colorado by ColoradoBiz magazine. About Room 214 Room 214 is a digital marketing and social media agency dedicated to helping brands connect with the people who matter most. Recognized as one of the Best Places to Work in America by Outside Magazine, a Top 250 Private Company by ColoradoBiz, and one of the fastest growing companies by Inc. Magazine, Room 214 succeeds by molding thoughtful insights into intriguing content -- and developing strategic marketing initiatives that integrate all facets of digital and social marketing for B2B and B2C companies. With headquarters in Boulder, Colo. services include: brand and messaging strategy; digital and social media campaign execution; consumer research and analytics; online advertising and search engine optimization; content creation with in-house copy, photography and video production capabilities. A sample of Room 214’s clients include: Sanrio (Hello Kitty), Panasonic, Boulder Brands, Crock-Pot, Mr. Coffee, Adobe, Verizon, Twitter, Western Union, Haribo and Whitewave Foods. Make the connection and join Room 214 in conversation at:, @Room_214,, and info(at)room214(dot)com.

Oldfield F.,University of Liverpool | Chiverrell R.C.,University of Liverpool | Lyons R.,University of Witwatersrand | Williams E.,Massachusetts Institute of Technology | And 6 more authors.
Aeolian Research | Year: 2014

Magnetic measurements and Diffuse Reflectance Spectroscopy are used in an attempt to differentiate dusts and dust sources in North Africa, over the Atlantic and in Barbados. Special attention is paid to dusts and to lacustrine clay and diatomite samples from the Bodélé Depression, in view of its alleged importance in trans-Atlantic and global dust generation. The results indicate that dusts from the Bodélé Depression can be distinguished from other dusts and potential sources in Niger, Chad, Burkina and Mali on the basis of their magnetic properties, notably their low magnetic concentrations, negligible frequency dependent magnetic susceptibility and distinctive IRM demagnetization characteristics. Dust from over the Atlantic and from Barbados, obtained from meshes in the 1960s and '70s have high frequency dependent susceptibility values, are quite distinctive from the Bodélé Depression samples and are more closely comparable to samples from elsewhere in the Sahara and especially the Sahel. The Diffuse Reflectance Spectroscopy data, though of limited value here, are not inconsistent with the inferences based on the magnetic measurements. Overall, the results obtained point to a wide range of sources for dusts both over North Africa itself and across the Atlantic. They do not offer support to the view that dusts from the Bodélé Depression have dominated supply across the Atlantic over the last five decades. © 2014 Elsevier B.V.

Kannan R.,CFD Research Corporation | Wang Z.J.,Room
Computers and Fluids | Year: 2010

The direct discontinuous Galerkin (DDG) method was developed by Liu and Yan to discretize the diffusion flux. It was implemented for the discontinuous Galerkin (DG) formulation. In this paper, we perform four tasks: (i) implement the direct discontinuous Galerkin (DDG) scheme for the spectral volume method (SV) method, (ii) design and implement two variants of DDG (called DDG2 and DDG3) for the SV method, (iii) perform a Fourier type analysis on both methods when solving the 1D diffusion equation and combine the above with a non-linear global optimizer, to obtain modified constants that give significantly smaller errors (in 1D), (iv) use the above coefficients as starting points in 2D. The dissipation properties of the above schemes were then compared with existing flux formulations (local discontinuous Galerkin, Penalty and BR2). The DDG, DDG2 and DDG3 formulations were found to be much more accurate than the above three existing flux formulations. The accuracy of the DDG scheme is heavily dependent on the penalizing coefficient for the odd ordered schemes. Hence a loss of accuracy was observed even for mildly non-uniform grids for odd ordered schemes. On the other hand, the DDG2 and DDG3 schemes were mildly dependent on the penalizing coefficient for both odd and even orders and retain their accuracy even on highly irregular grids. Temporal analysis was also performed and this yielded some interesting results. The DDG and its variants were implemented in 2D (on triangular meshes) for Navier-Stokes equations. Even the non-optimized versions of the DDG displayed lower errors than the existing schemes (in 2D). In general, the DDG and its variants show promising properties and it indicates that these approaches have a great potential for higher dimension flow problems. © 2010 Elsevier Ltd.

PubMed | Room
Type: Journal Article | Journal: Social cognitive and affective neuroscience | Year: 2014

Lifetime experiences shape peoples attitudes toward sexual stimuli. Visual sexual stimulation (VSS), for instance, may be perceived as pleasurable by some, but as disgusting or ambiguous by others. VSS depicting explicit penile-vaginal penetration (PEN) is relevant in this respect, because the act of penetration is a core sexual activity. In this study, 20 women without sexual complaints participated. We used functional magnetic resonance imaging and a single-target implicit association task to investigate how brain responses to PEN were modulated by the initial associations in memory (PEN-hot vs PEN-disgust) with such hardcore pornographic stimuli. Many brain areas responded to PEN in the same way they responded to disgust stimuli, and PEN-induced brain activity was prone to modulation by subjective disgust ratings toward PEN stimuli. The relative implicit PEN-disgust (relative to PEN-hot) associations exclusively modulated PEN-induced brain responses: comparatively negative (PEN-disgust) implicit associations with pornography predicted the strongest PEN-related responses in the basal forebrain (including nucleus accumbens and bed nucleus of stria terminalis), midbrain and amygdala. Since these areas are often implicated in visual sexual processing, the present findings should be taken as a warning: apparently their involvement may also indicate a negative or ambivalent attitude toward sexual stimuli.

PubMed | Room
Type: | Journal: Advances in experimental medicine and biology | Year: 2011

Stem cells are unspecialized precursor cells that mainly reside in the bone marrow and have important roles in the establishment of embryonic tissue. They also have critical functions during adulthood, where they replenish short-lived mature effector cells and regeneration of injured tissue. They have three main characteristics: self-renewal, differentiation and homeostatic control. In order to maintain a pool of stem cells that support the production of blood cells, stromal elements and connective tissue, stem cells must be able to constantly replenish their own number. They must also possess the ability to differentiate and give rise to a heterogeneous group of functional cells. Finally, stem cells must possess the ability to modulate and balance differentiation and self-renewal according to environmental stimuli and whole-organ needs to prevent the production of excessive number of effector cells.(1) In addition to formation of these cells, regulated movement of stem cells is critical for organogenesis, homeostasis and repair in adulthood. Stem cells require specific inputs from particular environments in order to perform their various functions. Some similar trafficking mechanisms are shared by leukocytes, adult and fetal stem cells, as well as cancer stem cells.(1,2) Achieving proper trafficking of stem cells will allow increased efficiency of targeted cell therapy and drug delivery.(2) In addition, understanding similarities and differences in homing and migration of malignant cancer stem cells will also clarify molecular events of tumor progression and metastasis.(2) This chapter focuses on the differentiation, trafficking and homing of the major types of adult bone marrow stem cells: hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs) and the termstem cell will refer to adult stem cells unless otherwise specified.

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