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Claudia C.,Romanian Academy INCE CSCBA | Horatiu S.,Romanian Academy INCE CSCBA | Iudith I.,Romanian Academy INCE CSCBA | Vasile B.,Romanian Academy INCE CSCBA
Romanian Biotechnological Letters | Year: 2014

In this study we want the tested the capsaicin (CPS) effect in activation the TRPV1 receptor in mouse sperm- acrosomial reaction. The role of vanilloid (TRPV1) in sperm functions involved in fertilization will be studied by evaluating the effect of capsaicin selective antagonists of TRPV1, on spontaneous and induced acrosome reaction (AR). The vanilloid (TRPV1) receptors, plays a crucial role in controlling functionality of sperm, with the impact on reproduction. The TRPV1 binding was detected in fertile sperm and this is reactive of the capsaicin caused the sperm membrane depolarization due to the Na+ influx and calcium channels (VGCC) opening. © 2014 University of Bucharest. Source

Iudith I.,Romanian Academy INCE CSCBA | Amalia S.,Romanian Academy INCE CSCBA | Horatiu S.,Romanian Academy INCE CSCBA | Mihai E.L.,Romanian Academy INCE CSCBA
Romanian Biotechnological Letters | Year: 2013

The Romanian Turcana sheep it is a national breed with multiple quality: adaptability in rough climate, rusticity but with insufficient production of actual necessity. The research team collected samples from animals in Transylvania area to identify valuable genotypes resistance to scrapie disease. For classical scrapie the codon 171 is thought to be the major determinant of susceptibility, with glutamine (Q) and histidine (H) conferring susceptibility and arginine (R) resistance. The results of county analysis shows evidence 46 alanine (A) at codon 136 that confers resistance to scrapie prion structural changes. The presence of glutamine (Q) or histidine at codon 171 may send some characters of resistance to scrapie that was not detected in these samples. The analytical results from 126 samples the presence of glutamine (Q) in codon 171 of prion structural changes that confer resistance to scrapie prion. It is identify the case of scrapie with clinical signs with genotype ARQ/ARQ considered very low susceptibility to scrapie in Europe. © 2013 University of Bucharest. Source

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