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Chaudhary V.,Rohilkhand Medical College and Hospital
Indian journal of public health | Year: 2010

The deadly disease swine flu is, without a speck of doubt, causing a massive havoc among the common people of India and has created fear across the various strata of the society. The objective was to find out the awareness, perception, and myths of school going children of class 9 th to 12 th toward swine flu. The present cross-sectional study was carried out in two randomly selected (using random number table) senior secondary schools of Bareilly among 400 students of class 9 th to 12 th . A total of 200 students were selected from each school. Chi-square test was applied for statistical analysis. Almost all the students (97.75%) have heard about of swine flu and are aware of it as a disease entity. Fever was found to be the main symptom while coughing and sneezing were main way of spread of swine flu known to them. About 97% of the students mention use of mask as most effective way to prevent them from swine flu. Knowledge of availability of medicine was present in less than half of the students. TV was found to be the main source from which they get knowledge (79%), and they are trying to get knowledge (53.2%) of swine flu. Among them, 74% students were taking precaution against swine flu. Source

Pokhrel A.K.,University of California at Berkeley | Bates M.N.,University of California at Berkeley | Verma S.C.,Regional Tuberculosis Center | Joshi H.S.,Rohilkhand Medical College and Hospital | And 2 more authors.
Environmental Health Perspectives | Year: 2010

Background: In Nepal, tuberculosis (TB) is a major problem. Worldwide, six previous epidemiologic studies have investigated whether indoor cooking with biomass fuel such as wood or agricultural wastes is associated with TB with inconsistent results. Objectives: Using detailed information on potential confounders, we investigated the associations between TB and the use of biomass and kerosene fuels. Methods: A hospital-based case-control study was conducted in Pokhara, Nepal. Cases (n = 125) were women, 20-65 years old, with a confirmed diagnosis of TB. Age-matched controls (n = 250) were female patients without TB. Detailed exposure histories were collected with a standardized questionnaire. Results: Compared with using a clean-burning fuel stove (liquefied petroleum gas, biogas), the adjusted odds ratio (OR) for using a biomass-fuel stove was 1.21 [95% confidence interval (CI), 0.48-3.05], whereas use of a kerosene-fuel stove had an OR of 3.36 (95% CI, 1.01-11.22). The OR for use of biomass fuel for heating was 3.45 (95% CI, 1.44-8.27) and for use of kerosene lamps for lighting was 9.43 (95% CI, 1.45-61.32). Conclusions: This study provides evidence that the use of indoor biomass fuel, particularly as a source of heating, is associated with TB in women. It also provides the first evidence that using kerosene stoves and wick lamps is associated with TB. These associations require confirmation in other studies. If using kerosene lamps is a risk factor for TB, it would provide strong justification for promoting clean lighting sources, such as solar lamps. Source

Singh A.,Rohilkhand Medical College and Hospital
Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH | Year: 2012

Although there has been a considerable reduction in the infective causes of ocular morbidity, the global burden of blindness has not significantly altered for over a decade. To find the extent of ocular morbidity in different subgroups of the rural population and to study the factors associated with ocular morbidity. A cross-sectional study was conducted at the Jasra and Saidabad blocks of Allahabad District. A total of eight villages were selected by multistage random sampling technique. The data were analyzed with SPSS Software. Among 9,736 people surveyed, 931 cases of eye diseases were identified. Ocular morbidity was highest (40.92 %) among those aged above 60 years. A higher morbidity was also observed among females (53.60 %), illiterates (69.50 %) and those belonging to low socioeconomic strata (42.86 %). The main causes of ocular morbidity in the study population were cataract (41.89 %), uncorrected refractive errors (21.59 %), xerophthalmia (10.20 %) and glaucoma ( 4.83 %). Programs for cataract surgery, detection and treatment of glaucoma, correction of refractive errors and vitamin A prophylaxis for xerophthalmia need to be targeted to further reduce the burden of ocular morbidity. © NEPjOPH. Source

Kapoor P.,Indraprastha Apollo Hospital | Kapoor A.K.,Rohilkhand Medical College and Hospital
Journal, Indian Academy of Clinical Medicine | Year: 2013

Coenzyme Q10 is a fat soluble vitamin-like substance produced by the human body. It is necessary for proper functioning of many organs and for basic functioning of cells. It is found throughout the body. Coenzyme Q10 is used both as a food supplement and as an important antioxidant. It is a component of the electron transport chain and plays a key role in producing energy in mitochondria in the form of ATP that functions like a rechargeable battery in the transfer of energy. Coenzyme Q10 levels are reported to decrease with age and to be low in cardiac conditions, Parkinson's disease, cancer, diabetes, muscular dystrophies, HIV/AIDs, etc. Some drugs also lower Coenzyme Q10 levels. It is not only used as an important nutrional supplement by millions of people all over world but is also used in a number of clinical conditions namely CHF, diabetes, gum disease, Huntington's disease, Parkinson's disease, etc. Coenzyme Q10 is fairly safe and well tolerated. Source

Pandey M.K.,Rohilkhand Medical College and Hospital | Mittra P.,Rohilkhand Medical College and Hospital | Maheshwari P.K.,P.A. College
Journal of Clinical and Diagnostic Research | Year: 2012

Context: Free radicals have been implicated in the development of acute and chronic diseases of the brain e.g. Epilepsy, Cerebrovascular diseases, Parkinson's disease, Alzheimer's disease, etc. The present study was designed to assess the oxidative stress in epilepsy, since very few of such studies have been designed in human beings. Aims: To study the level of the lipid peroxidation products i.e. malondialdehyde (MDA) as a marker of oxidative stress in epilepsy patients. Settings and Design: This case control study had 170 samples which comprised Group I(n-90) patients of epilepsy as the cases, which were compared with Group II (n-80) which were age and sex matched controls. Methods and Materials: The lipid peroxidation product i.e. MDA formation was estimated by assessing the levels of thio-barbituric acid reactive substances (TBARS) by using spectrophotometry. Statistical Analysis Used: The statistical analysis was done by using the SPSS software and the results were described by using the unpaired T test and p values. Results: In the present study, the mean MDA value in Group I (2.38 ±0.31) was significantly raised (p<0.01) than in Group II (2.15±0.36), thus suggesting that the MDA values were raised in epilepsy. The mean MDA level after 1 year of therapy was 2.25±0.25, with a p value of <0.05, thus suggesting a reduction in the oxidative stress with therapy. Conclusions: The level of the lipid peroxidation is significantly higher in epilepsy as compared to the control and oxidative stress increases which were found with the duration of the epilepsy. The oxidative stress had no significant difference in the males and females. The oxidative stress was found to reduce on adequate antiepileptic therapy. Source

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