Rāichūr, India
Rāichūr, India

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Nallam S.R.,RIMS | Chiruvella S.,RIMS | Karanam S.,RIMS
Indian Journal of Anaesthesia | Year: 2017

Background and Aims: The ideal dose of dexmedetomidine for brachial plexus block is a matter of debate. This study was carried out to evaluate 50 μg or 100 μg of dexmedetomidine added to 0.5% levobupivacaine, with regard to the duration of analgesia. Our study also sought to assess the onset and duration of sensorimotor blockade, haemodynamic effects, sedation and adverse effects. Methods: One hundred adult patients undergoing upper limb surgeries under supraclavicular brachial plexus block were randomly allocated into two groups. Group LD50 received 29 ml of 0.5% levobupivacaine plus 50 μg of dexmedetomidine diluted in 1 ml of normal saline. Group LD100 received 29 ml of 0.5% levobupivacaine plus 100 μg of dexmedetomidine diluted in 1 ml of normal saline. Duration of analgesia was the primary outcome. Onset and duration of sensorimotor blockade, haemodynamic variables, sedation score, and adverse effects were secondary outcomes. The data were analysed with Students’ t-test and Chi-square test. Results: The onset of sensory block and motor block was 14.82 ± 3.8 min and 19.75 ± 6.3 min, respectively, in group LD50, while it was 11.15 ± 1.7 min and 14.3 ± 4.2 min, respectively, in group LD100. The duration of analgesia was significantly prolonged in group LD100 (1033.6 ± 141.6 vs. 776.4 ± 138.6 min; P = 0.001). The incidence of bradycardia and sedation was observed in significantly more patients in group LD100. Significantly fewer patients in group LD100 required rescue analgesia. Conclusion: The 100 μg dose of dexmedetomidine in brachial plexus block hastens the onset and prolongs the duration of sensorimotor blockade and analgesia, but with higher incidence of bradycardia and sedation. © 2017 Indian Journal of Anaesthesia.

Samatha P.,RIMS | Venkateswarlu M.,RIMS | Siva Prabodh V.,NRIMS
Journal of Clinical and Diagnostic Research | Year: 2012

Introduction: Dyslipidaemia is one of the common disorders which is seen in most of the diabetes patients, which causes cardio vascular disorders.This study was conducted to compare the lipid profile of diabetic patients and healthy controls. Methods: The lipid profiles and the fasting blood sugar values of 160 known diabetics and 160 healthy subjects were studied. Their serum samples were assessed for fasting blood glucose (FBG), total cholesterol (TC), triacylglycerols (TG), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) by using standard biochemical methods. Results: The mean total cholesterol, triacylglycerols, LDL-C and the fasting blood sugar levels were highly significant in the diabetics as compared to those in the controls. The mean HDL-C concentration was non significantly lower in female diabetics as compared to that in the male diabetics. The correlation studies showed a non significant negative correlation of FBG with HDL-C and a positive correlation of FBG with TC, TG and LDL-C. Conclusion: The frequencies of the high TC, high TG and high LDL-C levels were higher in the diabetic group, thus indicating that diabetic patients were more prone for dyslipidaemia, which could cause cardiovascular disorders.

Patil B.,RIMS | Patil D.,Navodaya Medical College RaichurKarnataka
Indian Journal of Forensic Medicine and Toxicology | Year: 2016

This study conducted on 500 patients who visited the emergency and Casualty of RIMS Hospital, Raichur, Karnataka, India. To study the pattern of cases in the Casualty of hospital and to study the case mix pattern was the main objective of the study. Medicine and its allied specialties contributed to the maximum number of patients attending the casualty. Maximum number of patients visiting the casualty had small complaints and did not suff er from any life threatening problems, which actually required Care and admission for the purpose of emergency medical care. This results in increase of unnecessary workload for the staff working mainly in the Casualty, deputed there for providing emergency care. © 2015, Indian Journal of Forensic Medicine and Toxicology. All rights reserved.

COSTA MESA, Calif., Dec. 5, 2016 /PRNewswire/ -- According to the J.D. Power 2016 Large Commercial Insurance Study,SM the key variables driving overall commercial insurance customer satisfaction are insurer profitability and broker expertise. The highest-performing broker in this year's st...

Metri B.C.,BLDEUs Shri B M Patil Medical College | Jyothi P.,BLDEUs Shri B M Patil Medical College | Peerapur B.V.,RIMS
Indian Journal of Medical Sciences | Year: 2011

Background: Recently, the isolation of this pathogen in hospital settings is increasing and multidrug-resistant strains are emerging; these strains present a challenge for clinician and the clinical microbiologist because of their increased occurrence in nosocomial infection. The current study was done to find out the antibiotic sensitivity pattern of Citrobacter species from various clinical specimens. Materials and Methods: Samples were collected from patients in accordance with standard protocols. Citrobacter species were identified by conventional biochemical tests. Antibiotic susceptibility of the isolates was done by disc diffusion method according to National Committee for Clinical Laboratory Standards (NCCLS) recommendations. Results: Out of 563 isolates of Citrobacter, majority were from pus (48.1%), followed by urine (24.3%), sputum (20.3%), body fluids (05.2%), blood (02.1%). C. koseri was the predominant species [391 (70%)] isolated. Infection was nosocomialy acquired in 493 (87.4%) patients. The mean age was 39.5 years. Anti-biograms of Citrobacter isolates revealed that effective agent against Citrobacter isolates was imipenem (91.8% sensitive), followed by piperacillin/tazobactam (58.3%) and amikacin (53.4%). Conclusion: Citrobacter isolates resistant to multiple anti-microbial agents have emerged, including strains resistant to imipenem, making it an emerging nosocomial pathogen. Therefore, the results of this study suggest that surveillance of anti-microbial resistance in Citrobacter is necessary. Antibiotic policy should be formulated in the hospital. Depending on the antibiotic sensitivity pattern of the Citrobacter isolates, antibiotics should be used, and proper infection control measures should be strictly followed to prevent spread of this pathogen.

Pujari V.M.,R.I.M.S. | Suryakar A.N.,Dr Vm Government Medical College | Ireddy S.,R.I.M.S.
Biomedical Research | Year: 2010

The imbalance in to oxidants and antioxidants leads to the condition called oxidative stress. The oxidative stress is considered as one of the etiopathological factors for development and /or exacerbation of psoriasis. Therefore we undertook this study to determine serum levels of oxidants (Malondialdehyde MDA, Nitric oxide NO) and antioxidants (Total Antioxidant Status TAS, Superoxide Dismutase SOD) and it's correlation with severity of psoriasis. In present research work we have studied 90 clinically diagnosed psoriasis patients and 90 age and sex matched healthy control subjects. Our results showed increased concentration of oxidants; MDA, NO, and decreased concentration of TAS as well as activity of SOD in the serum of psoriasis patients. Observations of our study clearly indicate positive correlation of increasing serum oxidants and negative correlation of decreasing serum antioxidants with PASI scour i.e. severity of psoriasis.

Background: The stress response associated with laryngoscopy and intubation may have catastrophic sequelae especially in susceptible patients. We compared the attenuation of stress response with fentanyl citrate and lignocaine hydrochloride and saline (control). Methods: Following institutional ethical committee approval and written informed consent, ninety adult patients (ASA- I, 18-60 years of either sex) were enrolled in this randomized, double - blind placebo controlled study at RIMS hospital,Imphal during the period from August 2009 to July 2010. Patients were divided into three groups: Group A (n=30) to receive fentanyl citrate 2μg/kg IV 5 min before induction, Group B (n=30) to receive lignocaine hydrochloride 1.5 mg/kg IV and Group C (n=30) to receive saline (control). The parameters monitored were heart rate, blood pressure (systolic, diastolic and mean arterial pressure) every minute for the first 5 min. and then every 5 min. upto 20 minutes. Results: Fentanyl caused significant attenuation of the stress response during laryngoscopy and intubation (p=0.001 for HR, p= 0.003 for SBP and p=0.004 for MAP) compared with lignocaine or saline (placebo). We could not appreciate lignocaine to be superior to saline. Conclusion: Fentanyl citrate 2μg/kg IV given 5 min. before laryngoscopy and intubation significantly attenuated the stress response when compared with either lignocaine 1.5 mg/kg IV or saline.

Mudium R.,RIMS | Kolasani B.,RIMS
Journal of Clinical and Diagnostic Research | Year: 2014

Aims and objectives: The study was aimed to evaluate the anticonvulsant effect of hydro-alcoholic seed extract of croton tiglium in rats and mice. Materials and Methods: Forty eight each of rats and mice of either sex were randomised into four groups and subjected to seizures induced by electroconvulsiometer and pentylenetetrazole. The hydroalcoholic seed extract of croton tiglium (250 and 500mg/kg) was studied for its anticonvulsant effect using sodium valproate (200mg/kg) as standard and distilled water as control. The parameters observed were time for onset of HLE (Hind Limb Extension) and duration of HLE in electrically induced seizures, and time for onset of convulsions and duration of convulsions in chemically induced seizures. Mortality of the animals over 24 hours was observed in both the models. For testing statistical significance between various groups unpaired student t-test was used. Observations and Results: In electrically induced seizures croton tiglium produced dose dependant prolongation of time for onset of HLE and a reduction in duration of HLE and in chemically induced convulsions, it prolonged time for onset of convulsions and reduced the duration of convulsions indicating its anticonvulsant effect in both models. However anticonvulsant effect was less compared to sodium valproate. There was a higher percentage of mortality in croton tiglium group in chemically induced convulsions when compared to sodium valproate. Conclusion: Croton tiglium has dose dependant anticonvulsant effect in electrically induced seizures, while in pentylenetetrazole induced seizures the protection is very minimal.

Patil D.,Navodaya Medical College | Patil B.,RIMS
Indian Journal of Forensic Medicine and Toxicology | Year: 2016

100 patients diagnosed as suff ering from Hypertension were included for the study. About 100 healthy volunteers were also included in the control group. The finger print patterns observed between Hypertensive individuals and controls. Hypertensive patients showed increase in frequency of number of loops as compared to control group. Hypertensive patients also showed decrease in frequency of whorls as compared to the control group. However these findings were not statistically significant. © 2015, Indian Journal of Forensic Medicine and Toxicology. All rights reserved.

Patil D.,Navodaya Medical College | Patil B.,RIMS
Indian Journal of Forensic Medicine and Toxicology | Year: 2016

A survey was conducted on 200 medical students and interns in Navodaya medical college Raichur Karnataka India to assess their attitude and knowledge regarding medico legal autopsy. The study also included the knowledge of the procedure, attitude and perception towards medico legal autopsy. In present study majority of students were aware where medico legal post mortem examination is mandatory as per the laws followed in the country. They also have awareness regarding viscera for chemical analysis and histo pathological examination for the purpose of medico legal autopsy. 60%males and 40% females were included in the study. 97% medicos believed that medico legal autopsy is mandatory. 98% thought that autopsy means viscera examination for histo pathological examination and chemical analysis. 85% students opined that the post mortem examination is done to the cause of death 50% opined that post mortem examination means causing disfigurement of the dead body. 70% denied that the post mortem examination procedure is a disrespect to the dead body. 90% opined that they were knowledgeable about the procedure of post mortem examination. 50%were comfortable and another 50%were were not comfortable on the first exposure to post mortem examination procedure. 80% opined that students should watch more autopsies. 60% opined positively for conducting post mortem examination on relatives when required. 90% students said that they don’t have personal disliking for viewing autopsy and did not have unpeeled experience of them. © 2015, Indian Journal of Forensic Medicine and Toxicology. All rights reserved.

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