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Lawrenceville, NJ, United States

Rider University is a private, coeducational and nonsectarian university located chiefly in the Lawrenceville section of Lawrence Township in Mercer County, New Jersey, United States. It consists of five academic units: the College of Business Administration, the College of Liberal Arts, Education and science, the College of Continuing Studies, and the Westminster College of the Arts. In addition to regional accreditation, the undergraduate and graduate programs in business are accredited by AACSB, and the professional education graduate programs are accredited by NCATE. As of 2014 there are 5,400 undergraduate and graduate students attending. Wikipedia.

Grushow A.,Rider University
Journal of Chemical Education | Year: 2011

A rationale for the removal of the hybrid atomic orbital from the chemistry curriculum is examined. Although the hybrid atomic orbital model does not accurately predict spectroscopic energies, many chemical educators continue to use and teach the model despite the confusion it can cause for students. Three arguments for retaining the model in the chemical curriculum are presented. These arguments are then refuted and methods for teaching chemistry without invoking the hybrid atomic orbital model are presented to show how the model can be removed from the chemistry curriculum with little negative effect. Copyright © 2011 American Chemical Society and Division of Chemical Education, Inc. Source

Lowrey P.L.,Rider University | Takahashi J.S.,University of Texas Southwestern Medical Center
Advances in Genetics | Year: 2011

The mammalian circadian system is a complex hierarchical temporal network which is organized around an ensemble of uniquely coupled cells comprising the principal circadian pacemaker in the suprachiasmatic nucleus of the hypothalamus. This central pacemaker is entrained each day by the environmental light/dark cycle and transmits synchronizing cues to cell-autonomous oscillators in tissues throughout the body. Within cells of the central pacemaker and the peripheral tissues, the underlying molecular mechanism by which oscillations in gene expression occur involves interconnected feedback loops of transcription and translation. Over the past 10 years, we have learned much regarding the genetics of this system, including how it is particularly resilient when challenged by single-gene mutations, how accessory transcriptional loops enhance the robustness of oscillations, how epigenetic mechanisms contribute to the control of circadian gene expression, and how, from coupled neuronal networks, emergent clock properties arise. Here, we will explore the genetics of the mammalian circadian system from cell-autonomous molecular oscillations, to interactions among central and peripheral oscillators and ultimately, to the daily rhythms of behavior observed in the animal. © 2011 Elsevier Inc. Source

Spiegelberg B.D.,Rider University
Journal of Receptors and Signal Transduction | Year: 2013

Emerging data suggest that interaction with reversible protein acetylation is an important mediator of GPCR-initiated changes in transcription and other processes. Alteration of acetylation downstream of GPCR activation occurs through a variety of mechanisms, including kinase-dependent and-independent regulation of histone deacetylases (HDACs) and histone acetyltransferases (HATs). The prominence of both GPCR and acetylation in pathology and drug development efforts highlights the importance of understanding cross-talk between these two signaling mechanisms. © 2013 Informa Healthcare USA, Inc. Source

Grushow A.,Rider University
Journal of Chemical Education | Year: 2012

This letter is in response to those who do not wish to retire the hybrid atomic orbital model. The argument is made that students in general and organic chemistry lack the necessary background skills to properly understand orbital bonding models, and thus, teaching these models in these courses leads many students to generate misconceptions. © 2012 American Chemical Society and Division of Chemical Education, Inc. Source

Dombrowski S.C.,Rider University | Watkins M.W.,Baylor University
Psychological Assessment | Year: 2013

Development of the Woodcock-Johnson (3rd ed.; WJ-III; Woodcock, McGrew & Mather, 2001a) was guided in part by Carroll's (1993) 3-stratum theory of cognitive abilities and based on confirmatory factor analysis (CFA), even though Carroll used exploratory factor analysis (EFA) to derive his theory. Using CFA, McGrew and Woodcock (2001) found a 9-factor model across all age ranges. To determine if the 9-factor structure holds for the full WJ-III battery, we applied currently recognized best practices in EFA to 2 school-aged 42-subtest correlation matrices (ages 9-13 and 14-19 years). Six factors emerged at the 9-13 age range, while 5 factors were indicated at the 14-19 age range. The resulting 1st-order factors displayed patterns of both convergence with and divergence from the WJ-III results presented in the Technical Manual. These results also revealed a robust manifestation of general intelligence (g) that dwarfed the variance attributed to the lower order factors. It is surprising that this study represents the first time the WJ-III full battery was subjected to EFA analyses given the instrument's significant use by practitioners and that it served as the initial evidentiary basis for Cattell-Horn-Carroll (CHC) theory. The lack of confirmation of CFA results with EFA methods in the current study permits questioning of the structure of the WJ-III and its relationship with CHC theory. Additional independent, structural analyses are clearly indicated for the WJ-III full test battery before we can be confident in its structure. © 2013 American Psychological Association. Source

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