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Edinburgh of the Seven Seas, Saint Helena

Smith J.K.,RHSC Edinburgh
BMJ case reports | Year: 2010

Infantile botulism is a rare cause of neuromuscular weakness resulting from ingestion of Clostridium botulinum-an anaerobic Gram-positive bacillus found universally in soil. The only definite food source known to cause infantile botulism is honey; previously, links to formula milk have been postulated but not definitely sourced. We present an interesting case report of a 2-month-old infant with this rare condition, including the diagnostic difficulties that ensued. A brief overview of the condition follows. This is the first case in the UK in which C botulinum was successfully isolated from both the patient and the suspected source-a jar of honey. The importance of food labelling as a public health message is highlighted. Source


Smith J.K.,RHSC Edinburgh | Al-Essa S.,St Johns Hospital | Ramlingham S.,Royal Infirmary
BMJ Case Reports | Year: 2010

This case report describes twins presenting approximately 24 h apart both with enterovirus meningoencephalitis. The presenting symptoms are described along with laboratory results. Both had extremely high white cell counts in cerebrospinal fluid, which were predominantly lymphocytes. Clinical course and outcomes are described. There was a potential delay in diagnosis of the second twin given the pathology of the twin sibling and the symptoms presented. Source


Smith J.K.,RHSC Edinburgh
BMJ case reports | Year: 2010

This case report describes twins presenting approximately 24 h apart both with enterovirus meningoencephalitis. The presenting symptoms are described along with laboratory results. Both had extremely high white cell counts in cerebrospinal fluid, which were predominantly lymphocytes. Clinical course and outcomes are described. There was a potential delay in diagnosis of the second twin given the pathology of the twin sibling and the symptoms presented. Source


Smith J.K.,RHSC Edinburgh | Burns S.,PICU | Cunningham S.,RHSC Edinburgh | Freeman J.,PICU | And 2 more authors.
BMJ Case Reports | Year: 2010

Infantile botulism is a rare cause of neuromuscular weakness resulting from ingestion of Clostridium botulinum - an anaerobic Gram-positive bacillus found universally in soil. The only definite food source known to cause infantile botulism is honey; previously , links to formula milk have been postulated but not definitely sourced. We present an interesting case report of a 2-month-old infant with this rare condition, including the diagnostic difficulties that ensued. A brief overview of the condition follows. This is the first case in the UK in which C botulinum was successfully isolated from both the patient and the suspected source - a jar of honey. The importance of food labelling as a public health message is highlighted. Source

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