Reutlingen, Germany
Reutlingen, Germany

Reutlingen University is a university of applied science in Reutlingen in the southern German state of Baden-Württemberg. Enrollment stands at about 5,800 students, a quarter of whom are international and exchange students. Reutlingen University's campus sits on the southwestern edge of Reutlingen, close to recreation and sport areas . Two bus lines serve the campus, and the town center is a 20-minute walk away. Two neighborhood centers are each a five-minute walk from campus and the dormitories, featuring shopping centers, banks, and doctors.The university offers undergraduate and graduate programs in the main fields of: International business Information and organization Technologies . Wikipedia.


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News Article | November 2, 2016
Site: www.prnewswire.com

Cadence, X-FAB, Coventor and Reutlingen University offering a first prize of $5000 for leading-edge ingenuity in MEMS and mixed-signal designs SAN JOSE, Calif., Nov. 2, 2016 /PRNewswire/ -- Cadence Design Systems, Inc. (NASDAQ: CDNS), Coventor, X-FAB and Reutlingen University have...


Steinbuch R.,Reutlingen University
Journal of Bionic Engineering | Year: 2011

The optimisation of earthquake resistance of high buildings by multi-tuned mass dampers was investigated using bionic algorithms. In bionic or evolutionary optimisation studies the properties of parents are crossed and mutated to produce a new generation with slightly different properties. The kids which best satisfy the object of the study, become the parents of the next generation. After a series of generations essential improvements of the object may be observed. Tuned mass dampers are widely used to reduce the impact of dynamic excitations on structures. A single mass system and multi-mass oscillators help to explain the mechanics of the dampers. To apply the bionic optimisation strategy to high buildings with passive tuned mass dampers subject to seismic loading a special beam element has been developed. In addition to the 6 degrees of freedom of a conventional beam element, it has 2 degrees of freedom for the displacements of the dampers. It allows for fast studies of many variants. As central result, efficient designs for damping systems along the height of an edifice are found. The impact on the structure may be reduced essentially by the use of such dampers designed to interact in an optimal way. © 2011 Jilin University.


Chen D.Q.,Texas Christian University | Mocker M.,Reutlingen University | Mocker M.,Erasmus University Rotterdam | Preston D.S.,Texas Christian University | Teubner A.,University of Munster
MIS Quarterly: Management Information Systems | Year: 2010

Information systems strategy is of central importance to IS practice and research. Our extensive review of the literature suggests that the concept of IS strategy is a term that is used readily; however, it is also a term that is not fully understood. In this study, we follow a perspective paradigm based on the strategic management literature to define IS strategy as an organizational perspective on the investment in, deployment, use, and management of IS. Through a systematic literature search, we identify the following three conceptions of IS strategy employed implicitly in 48 articles published in leading IS journals that focus on the construct of IS strategy: (1) IS strategy as the use of IS to support business strategy; (2) IS strategy as the master plan of the IS function; and (3) IS strategy as the shared view of the IS role within the organization. We find the third conception best fits our defi-nition of IS strategy. As such, we consequently propose to operationalize IS strategy as the degree to which the organi-zation has a shared perspective to seek innovation through IS. Specifically, our proposed IS strategic typology suggests an organization's IS strategy falls into one of the two defined categories (i.e., IS innovator or IS conservative) or is simply undefined. We also develop measures for this new typology. We argue that the proposed instrument, which was cross-validated across both chief information officers and senior business executives, has the potential to serve as a diagnostic tool through which the organization can directly assess its IS strategy. We contend that our reconceptualization and operationalization of IS strategy provides theoretical and practical implications that advance the current level of understanding of IS strategy from extant studies within three predominant literature streams: strategic IS planning, IS/business strategic alignment, and competitive use of IS.


Since November 2011 the standard DIN 4709 stipulates performance tests for Micro-CHP units in Germany. In contrast to steady state measurements of the CHP unit itself, the test according to DIN 4709 includes the thermal storage tank as well as the internal control unit, and it is based on a 24 h test cycle following a specified thermal load profile. Hence, heat losses from the storage tank are as well taken into account as transient losses of the CHP unit. In addition, the control strategy for loading and unloading the storage tank affects the test results. The DIN 4709 test cycle has been applied at the test stand for Micro-CHP units at Reutlingen University, and results for the Micro-CHP unit WhisperGen and the EC Power units XRGI 15® and XRGI 20® are available. During the analysis a method has been developed to evaluate the results in case the test cycle does not end in a time slot between 24 and 24.5 h after the starting as demanded by DIN 4709. Since this method has been successfully applied to the test of various CHP units of different size and technology so far, it is suggested to incorporate it to DIN 4709 during the next revision of the standard. The performance numbers obtained reveal the differences in efficiencies measured at steady-state on the one hand and following the DIN 4709 test cycle on the other hand. While the deviations in electrical efficiencies are small, thermal efficiencies according to DIN 4709 fall below steady state data by 3-6 percentage points. This is attributed to transient thermal losses and heat losses from the storage tank, which are not included in steady state and separate testing of the CHP unit, only. © 2013 Elsevier Ltd.


A system-wide analysis of cell signaling requires detecting and quantifying many different proteins and their posttranslational modification states in the same cellular sample. Here, we present Protocols for two miniaturized, array-based methods, one of which provides detailed information on a central signaling protein and the other of which provides a broad characterization of the surrounding signaling network. We describe a bead-based array and its use in characterizing the different forms and functions of β-catenin, as well as lysate microarrays (reverse-phase protein arrays) and their use in detecting and quantifying proteins involved in the canonical and noncanonical Wnt signaling pathways. As an application of this dual approach, we characterized the state of β-catenin signaling in cell lysates and linked these molecule-specific data with pathway-wide changes in signaling. The Protocols described here provide detailed instructions for cell culture methods, bead arrays, and lysate microarrays and outline how to use these complementary approaches to obtain insight into a complex network at a systems level.


Zolghadr K.,Reutlingen University
Methods in molecular biology (Clifton, N.J.) | Year: 2012

The understanding of cellular processes and their physiopathological alterations requires comprehensive data on the abundance, distribution, modification and interaction of cellular components. On the one hand, artificially introduced fluorescent fusion proteins provide information about their distribution and dynamics in living cells but not on endogenous factors. On the other hand, antibodies can detect endogenous proteins, posttranslational modifications and other cellular components but mostly in fixed and permeabilized cells. Here we highlight a new technology based on the antigen-binding domain of heavy-chain antibodies (VHH) from Camelidae. We have demonstrated that these VHH domains can be fused with fluorescent proteins and expressed in living cells. Those fluorescent antigen-binding proteins-called chromobodies-can be used to detect and trace proteins and other cellular components in vivo. In principle chromobodies can detect any antigenic structure including posttranslational modifications or nonprotein components and thereby dramatically expand the quality and quantity of information that can be gathered in high-content analyses. Here we demonstrate the suitability of this technology to follow apoptosis in living cells in real time.


Bell C.-M.,Reutlingen University
Chemical Engineering and Processing: Process Intensification | Year: 2016

In thermopervaporation the same economically favorable driving force as in membrane distillation, i.e., a temperature difference between feed and permeate for the transport, is used but with non-porous thin-film composite membranes. Membrane pores cannot be wetted and long-term operational stability can be achieved with the appropriate coating layer, but normally with a decrease of the flux compared to membrane distillation with porous hydrophobic membranes.Porous asymmetric PVDF membranes were made to achieve low permeation resistance and pores which could be overcoated with polyelectrolyte polymers. This coating prohibits pore wetting and strongly reduces adsorption of organic substances.Those membranes showed a high permeation rate for water due to a structure of phase-separated hydrophilic and hydrophobic three-dimensional domains. The permeation rates of these composite membranes for water is between 6 and 12 l/(h m2) at a feed temperature of 60 °C and permeate at a temperature of 40 °C of a 2% saline solution feed depending on the operational parameters. This is only a slight reduction of 10-15% in permeation rate compared to membrane distillation with porous hydrophobic membranes.In whey dewatering experiment this membrane showed a constant performance over 4 days in intermittent operation mode and stability in cleaning with strong alkaline solution. © 2016 Elsevier B.V.


This article examines the impact of international power politics on trade liberalization and organized labour. Using regional and bilateral free trade agreements (FTAs) in the Asia-Pacific region as a case study, it discusses how China's economic rise and the ensuing interstate rivalry in the region have contributed to the proliferation of FTAs. In examining the politics of nation-states and organized labour in the Asia-Pacific with regard to FTAs, it identifies economic nationalism as a barrier to transnational labour solidarity. With a critical examination of alternative trade policies, this article explores alternative venues for global social justice and labour solidarity. © 2014 © 2014 Taylor & Francis.


Yu X.,Reutlingen University | Schneiderhan-Marra N.,Reutlingen University | Joos T.O.,Reutlingen University
Clinical Chemistry | Year: 2010

BACKGROUND: Over the last 10 years, DNA microarrays have achieved a robust analytical performance, enabling their use for analyzing the whole transcriptome or for screening thousands of single-nucleotide polymorphisms in a single experiment. DNA microarrays allow scientists to correlate gene expression signatures with disease progression, to screen for disease-specific mutations, and to treat patients according to their individual genetic profiles; however, the real key is proteins and their manifold functions. It is necessary to achieve a greater understanding of not only protein function and abundance but also their role in the development of diseases. Protein concentrations have been shown to reflect the physiological and pathologic state of an organ, tissue, or cells far more directly than DNA, and proteins can be profiled effectively with protein microarrays, which require only a small amount of sample material. CONTENT: Protein microarrays have become wellestablished tools in basic and applied research, and the first products have already entered the in vitro diagnostics market. This review focuses on protein microarray applications for biomarker discovery and validation, disease diagnosis, and use within the area of personalized medicine. SUMMARY: Protein microarrays have proved to be reliable research tools in screening for a multitude of parameters with only a minimal quantity of sample and have enormous potential in applications for diagnostic and personalized medicine. © 2009 American Association for Clinical Chemistry.


Patent
Reutlingen University | Date: 2015-06-24

The invention relates to a method for a marker-free demarcation of distinct areas of a tissue in vitro, comprising the steps of recording at least two different spectra and/or spectral images of the tissue, analyzing the recorded spectra and/or spectral images by a multivariate data analysis to segment the tissues into distinct areas of similar spectral signature, and classifying each area as physiological, pathological or dead according to its spectral signature.

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