Monastir, Tunisia
Monastir, Tunisia

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Souid G.,Research Unit Mycotoxines | Souayed N.,Research Unit Mycotoxines | Yaktiti F.,Research Unit Mycotoxines | Maaroufi K.,Research Unit Mycotoxines
Ecotoxicology and Environmental Safety | Year: 2013

Cadmium (Cd) is a non-essential metal which could be toxic in traces for aquatic species. Increasing Cd concentrations in sea water is mainly related to waste waters provided from growing industrial and agricultural activities. The present study investigated the accumulation of Cd (0.5. mg/L) in different tissues of Sparus aurata under a short term exposure (2, 4 and 24. h) using the atomic absorption. This work investigated also the impact of the metal on oxidative stress biomarkers and acetyl cholinesterase activity (AchE). Our results showed that Cd accumulation in different tissues depends largely on the length of the exposure period to the metal. Indeed, the highest concentrations were obtained after 24. h. Cd accumulation in tissues was in the following order: intestines>liver>gills>dorsal muscle. Cadmium administration increased significantly catalase activity (CAT), glutathione level (GSH) and malondialdehyde production (MDA) after 24. h of exposure. In contrast, AchE activity was decreased after the same period of exposure to the metal. There were no significant changes in oxidative stress biomarkers after 2 and 4. h of exposure, except for superoxide dismutase (SOD) activity which attained the highest level after 4. h. These results suggest that short-term exposure of Sparus aurata to Cd (0.5. mg/L) induced an important metal accumulation in intestine and a notable oxidative stress response. © 2012.


Souid G.,Research Unit Mycotoxines | Souayed N.,Research Unit Mycotoxines | Yaktiti F.,Research Unit Mycotoxines | Maaroufi K.,Research Unit Mycotoxines
Drug and Chemical Toxicology | Year: 2015

The present work aimed to look at the distribution and accumulation pattern of Lead (Pb) within the fish body after 2 h, 4 h and 24 h of waterborne exposure to the metal at 0.75 mg/L. Tests of lead acute toxicity and bioaccumulation were performed in the common fish species Sparus aurata. In our study, we assessed the oxidative stress damages extent after 2 h, 4 h and 24 h of exposure to lead using the enzymatic stress biomarkers: Superoxide Dismutase (SOD), Catalase (CAT) and Gluthathione (GSH). The lipid peroxidation (LPO) was also investigated by dosing Malondyhaldéhyde (MDA) quantities in the liver tissue. The acute neurotoxicity of Pb was evaluated in the dorsal white muscle using the Acethylcholenesterase (AchE) activity. The liver tissue accumulates preferentially the metal, followed by the intestines, the gills and finally the dorsal muscle. The antioxidant response failed to prevent the lipid peroxidation and the neurotoxic effect of lead after 24 h of exposure. © 2015 Informa Healthcare USA, Inc. All rights reserved.

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