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Bagirova N.S.,Research Institute of Clinical Oncology
Klinichescheskaya Laboratornaya Diagnostika | Year: 2015

The diagnostic of infections of blood flow using technique of hemofermentation (blood inoculation) is one of the most significant functions oflaboratory of clinical microbiology. The effectiveness of the given technique depends on many factors, includingcriteria of evaluation of clinical significance of episode of bacteriemia and isolated microorganism applied by physician-microbiologist. The intelligent analysis of received results is needed. The physician-microbiologist has to determine ifmicroorganism isolated from given blood sample, is a genuine agent of infections of blood flow or it is only effect of contamination of analyzed sample at certain stage. The article presents data concerning taxonomic structure of microorganisms isolated under episodes of bacteriemia of adult oncologic hematologic patients during 2005-2013. The criteria of evaluation of clinical significance of episode of bacteriemia and isolated microorganism are described. The given criteria are developed in the N.N. Blokhin Russian oncological research center and are applied since 1977. The cases of contamination and genuine bacteriemia are established. The comparative analysis of international data and results of one's own study are carried out. Source

Nechushkina I.V.,Research Institute of Pediatric Oncology and Hematology | Karseladze A.I.,Research Institute of Clinical Oncology
Voprosy Onkologii | Year: 2015

Morphological structure of tumor influences on the clinical course of the disease in children with germ cell tumors. Patients with ovarian dysgerminoma at the time of diagnosis are significantly older than patients with immature teratoma and yolk sac tumor. Immature teratoma and mixed germ cell tumors are significantly larger compared to other germ cell tumors. Yolk sac tumor and embryonal carcinoma are the most common cause of emergency surgical interventions and are accompanied by rupture of tumor capsule. Source

Trusilova E.V.,Research Institute of Clinical Oncology | Besova N.S.,Research Institute of Clinical Oncology | Bagrova S.G.,Research Institute of Clinical Oncology | Gorbunova V.A.,Research Institute of Clinical Oncology | And 2 more authors.
Voprosy Onkologii | Year: 2013

There is presented the clinical observation of combined treatment of a patient with metastatic gastric cancer. The patient underwent combined chemotherapy for metastatic initially inoperative gastric cancer with metastases to the liver, paragastric lymph nodes as well as canceromatosis of the peritoneum with complete resorption of distant metastases, which allowed performing radical surgery. As a result of the combined treatment the patient is currently under dynamic observation without signs of disease. Duration of the patient's life at the moment is 44 months. Source

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