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Zincir S.B.,Research Hospital for Psychiatric and Neurological Disorders | Izci F.,Research Hospital for Psychiatric and Neurological Disorders | Eratalay A.,Research Hospital for Psychiatric and Neurological Disorders | Semiz U.B.,Research Hospital for Psychiatric and Neurological Disorders
Klinik Psikofarmakoloji Bulteni | Year: 2014

Interferon alpha (IFN- α) is commonly used in the treatment of viral hepatitis because of its stimulating effects on the immune response. While psychiatric adverse effects such as depression, mania or psychosis that arise during interferon alpha treatment have been well documented in the literature, the data regarding interferon-induced obsessive-compulsive disorder is rare. The case of a 59-year-old woman, who developed obsessive compulsive disorder and depression during interferon treatment for hepatitis C is presented here. This paper emphasizes the importance of regular monitoring and early treatment intervention for psychiatric symptoms and interdisciplinary collaboration during the course of interferon therapy in the early treatment period.


Bozkurt Zincir S.,Research Hospital for Psychiatric and Neurological Disorders | Sunbul M.,Marmara University | Zincir S.,Golcuk Military Hospital | Aydin Sunbul E.,Research Hospital for Psychiatric and Neurological Disorders | And 5 more authors.
Scientific World Journal | Year: 2014

Background. The primary purpose of this study was to investigate adult-child caregiver burden in heart failure (HF) patients. Secondary purpose of the study was to identify the possible influencing factors for caregiver burden and depressive symptoms in a young adult-child caregiver group. Methods. A total of 138 adult-child caregivers and 138 patients with HF participated in this study. Caregivers' burden, depressive symptoms, and anxiety levels were assessed by using Zarit Caregiver Burden Scale (ZCBS), Beck Depression Inventory, and State-Trait Anxiety Inventory, respectively. Results. The mean ZCBS scores of the female caregivers were significantly higher than male caregivers. Approximately one-third of the adult-child caregivers had at least mild depressive symptoms. Caregivers with higher depressive symptoms had higher levels of caregiver burden. There were positive correlations between caregiving time, severity of depressive symptoms, and perceived caregiver burden. There was a negative correlation between education level of caregivers and perceived caregiver burden. Age, socioeconomic level, and marital status of patients were affecting factors for depressive symptoms in caregivers. Among caregiver characteristics, gender, marital status, and ZCBS scores seem to influence the depression in caregivers. Conclusions. The study findings suggest significant levels of burden and depressive symptoms even in adult-child caregivers of HF patients. © 2014 Selma Bozkurt Zincir et al.

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