Drabowicz J.,Polish Academy of Sciences |
Drabowicz J.,Jan Dlugosz University in Czestochowa |
Krasowska D.,Polish Academy of Sciences |
Lopusinski A.,Polish Academy of Sciences |
And 2 more authors.
Current Organic Chemistry | Year: 2010
This review presents the use of cyclic tri- and pentavalent amidoesters and diamides with a stereogenic phosphorus as chiral stoichiometric auxiliaries in asymmetric synthesis. It shows that these compounds are especially useful for the preparation of selected acyclic enantiomerically (diastereomerically) pure (or enriched) tricoordinated-trivalent and tetracoordinated-pentavalent derivatives and as precursors of stereogenic phosphorus-containing carbanions. Their utility in a few other asymmetric reactions is also discussed.
De Blieck A.,Research Group SynBioC |
Masschelein K.G.R.,Research Group SynBioC |
Dhaene F.,Research Group SynBioC |
Rozycka-Sokolowska E.,Jan Dlugosz University in Czestochowa |
And 3 more authors.
Chemical Communications | Year: 2010
Trialkyl and silylated dialkyl phosphites were evaluated as phosphorus nucleophiles for the addition to quinolines in a strong acidic medium allowing consecutive 1,4- and 1,2-addition breaking up the aromatic stabilisation, thereby leading to 2,4-diphosphono-1,2,3,4-tetrahydroquinolines in one single reaction step in moderate to good yields (2-84%). © 2010 The Royal Society of Chemistry.