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Ferreira-Dias S.,University of Lisbon | Sandoval G.,Research Center istencia En Tecnologia seno Del Estado Of Jalisco | Plou F.,CSIC - Institute of Catalysis | Valero F.,Autonomous University of Barcelona
Electronic Journal of Biotechnology | Year: 2013

The potential of lipases (E.C. as biocatalysts for the production of fatty acid derivatives for the food and nutraceutical industries, such as flavouring esters, fatty acid esters of antioxidants and structured lipids, is enormous, mainly due to their high regio- and stereo-selectivities, in addition to the other well-known advantages of enzymatic processes. The replacement of chemical catalysts by lipases presents great benefits in terms of the nutritional properties of the obtained products and environmental care. The reactions performed for the production of these compounds, as well as the best operation conditions, the biocatalysts used, reactor types and operation mode, are addressed in this review. © 2013 by Pontificia Universidad Católica de Valparaíso, Chile.

Cuellar-Cruz M.,Research Center istencia En Tecnologia seno Del Estado Of Jalisco | Vega-Gonzalez A.,University of Guanajuato | Mendoza-Novelo B.,University of Guanajuato | Lopez-Romero E.,University of Guanajuato | And 3 more authors.
European Journal of Clinical Microbiology and Infectious Diseases | Year: 2012

Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis are able to form biofilms on virtually any biomaterial implanted in a human host. Biofilms are a primary cause of mortality in immunocompromised and hospitalized patients, as they cause recurrent and invasive candidiasis, which is difficult to eradicate. This is due to the fact that the biofilm cells show high resistance to antifungal treatments and the host defense mechanisms, and exhibit an excellent ability to adhere to biomaterials. Elucidation of the mechanisms of antifungal resistance in Candida biofilms is of unquestionable importance; therefore, this review analyzes both the chemical composition of biomaterials used to fabricate the medical devices, as well as the Candida genes and proteins that confer drug resistance. © Springer-Verlag 2012.

Baigts Allende D.,Research Center istencia En Tecnologia seno Del Estado Of Jalisco
Vitae | Year: 2016

Concern for the preservation of natural resources to the food supply due to rapid population growth has led to the exploration of alternative food sources that meet the demands of society. The need for a sustainable diet that reduces the environmental impact but that does not compromise the quality of the food is led by emergent protein producing that play the role of animal proteins but which are highly available, efficient and low cost. The use of foliar biomass for the production of proteins is seen as a viable option for sustainable food production to supply the nutritional demands and to be used as techno-functional ingredients in the development of food products by studying the molecular structure of proteins at different length scales and their interaction in order to determine the final products characteristics. © 2016, Universidad de Antioquia. All rights reserved.

Evangelista-Martinez Z.,Research Center istencia En Tecnologia seno Del Estado Of Jalisco
World Journal of Microbiology and Biotechnology | Year: 2014

The use of antagonist microorganisms against fungal plant pathogens is an attractive and ecologically alternative to the use of chemical pesticides. Streptomyces are beneficial soil bacteria and potential candidates for biocontrol agents. This study reports the isolation, characterization and antagonist activity of soil streptomycetes from the Los Petenes Biosphere Reserve, a Natural protected area in Campeche, Mexico. The results showed morphological, physiological and biochemical characterization of six actinomycetes and their inhibitory activity against Curvularia sp., Aspergillus niger, Helminthosporium sp. and Fusarium sp. One isolate, identified as Streptomyces sp. CACIS-1.16CA showed the potential to inhibit additional pathogens as Alternaria sp., Phytophthora capsici, Colletotrichum sp. and Rhizoctonia sp. with percentages ranging from 47 to 90 %. This study identified a streptomycete strain with a broad antagonist activity that could be used for biocontrol of plant pathogenic fungi. © 2013 Springer Science+Business Media Dordrecht.

Flores-Valdez M.A.,Research Center istencia En Tecnologia seno Del Estado Of Jalisco
Frontiers in Microbiology | Year: 2016

Tuberculosis (TB) remains as a global public health problem. In recent years, experimental evidence suggesting the relevance of in vitro pellicle (a type of biofilm formed at the air-liquid interface) production as a phenotype mimicking aspects found by Mycobacterium tuberculosis-complex bacteria during in vivo infection has started to accumulate. There are still opportunities for better diagnostic tools, therapeutic molecules as well as new vaccine candidates to assist in TB control programs worldwide and particularly in less developed nations. Regarding vaccines, despite the availability of a live, attenuated strain (Mycobacterium bovis BCG) since almost a century ago, its variable efficacy and lack of protection against pulmonary and latent disease has prompted basic and applied research leading to preclinical and clinical evaluation of up to 15 new candidates. In this work, I present examples of vaccines based on whole cells grown as biofilms, or specific proteins expressed under such condition, and the effect they have shown in relevant animal models or directly in the natural host. I also discuss why it might be worthwhile to explore these approaches, for constructing and developing new vaccine candidates for testing their efficacy against TB. © 2016 Flores-Valdez.

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