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Ghanizadeh A.,Research Center for Psychiatry and Behavioral science | Nouri S.Z.,Shiraz University of Medical Sciences | Nabi S.S.,Shiraz University of Medical Sciences
Eastern Mediterranean Health Journal | Year: 2012

Data are lacking about the prevalence of psychiatric disorders and suicidal behaviour in incarcerated adolescents in Asia. This cross-sectional study evaluated the prevalence of psychiatric disorders and the prediction of suicidal attempts in 100 incarcerated males aged 12-19 years in Shiraz. Data were collected in face-to-face interview using the Kiddie Schedule for Affective Disorders and Schizophrenia (Farsi version). The mean age was 16.8 (SD 1.3) years and mean age at first imprisonment was 16.0 (SD 1.5) years. Nearly 70% of the adolescents had at least one current psychiatric disorder, the commonest being: conduct disorder (55%), oppositional defiant disorder (48%) and attention deficit hyperactivity disorder (33%); 11% had major depressive disorder and 2% schizophrenia. In all, 20% had self-harmed without intent to kill themselves and 12% had attempted suicide, 50% of whom had tried more than once. In logistic regression analysis only self-harming behaviour and major depressive disorder were significant predictors of attempted suicide.

Ghanizadeh A.,Shiraz University of Medical Sciences | Ghanizadeh A.,Research Center for Psychiatry and Behavioral science | Faghih M.,Shiraz University of Medical Sciences
Sleep and Breathing | Year: 2011

Purpose: The aim of this study was to compare sleep problem categories of children with mental retardation without general medical condition (MR-GMC), children with MR co-occurring with GMC (MR+GMC), siblings of the MR children, and the general population. Method: This is the first study which separates MR children with GMC and those without GMC. The Children's Sleep Habits Questionnaire was completed by their parents to assess their children's sleep practices and behaviors such as the child's sleeping habits, sleeping arrangements, sleep anxiety, night wakening, parasomnias, and daytime sleepiness. Results: The clusters of bedtime resistance and sleep duration, wake up, parasomnia, sleep anxiety, and other problem categories were not different between MR children without GMC and the other two control groups of general population and siblings group. Parasomnia and other problem categories were more impaired in MR+GMC group than the three groups of MR-GMC, general population, and siblings. Conclusions: The lack of difference between the MR+GMC group and those in the control groups may suggest that medical predisposing factors may contribute to an increased rate of sleep problems in MR children, rather than their MR as a cause of sleep problems. Probably, management of the accompanying medical conditions of the MR children would improve their sleep; in other words, the sleep difficulties of the children with MR are more related to their general medical problems rather than their MR. © 2009 Springer-Verlag.

Ghanizadeh A.,Research Center for Psychiatry and Behavioral science | Ghanizadeh A.,Shiraz University of Medical Sciences
European Review for Medical and Pharmacological Sciences | Year: 2013

OBJECTIVE: Bruxism or sleep jaw clenching and grinding of the teeth is an unresolved area in dentistry, psychiatry, and medicine. While many therapeutic approaches are introduced, nearly all of them are not effective or some of them are invasive approach. Three children with sleep bruxismt-reated with hydroxyzine are reported. STUDY DESIGN: The parents reported the severity of sleep bruxism in their children. All the children used to co-sleep with their parents. Hydroxyzine 10 to 25 mg per night was administered for all of the three patients. They were followed up for one to two months. None of them had any remarkable general medical condition or temporomandibular joint problem. RESULTS: The parents reported a significant reduction in the score of Visual Analog Scale (VAS) after taking hydroxyzine for one month. Drug adverse effect was not reported or found. CONCLUSIONS: These reports suggest that hydroxyzine may be effective for the treatment of bruxism in children. It is worthwhile conducting placebo-controlled studies investigating the possible role of hydroxyzine for the treatment of bruxism in children.

Ghanizadeh A.,Research Center for Psychiatry and Behavioral science | Ghanizadeh A.,Shiraz University of Medical Sciences
Nordic Journal of Psychiatry | Year: 2015

Background: No published systematic review has ever assessed the efficacy and safety of reboxetine for treating of patients with attention deficit hyperactivity disorder (ADHD). Aim: This systematic review aimed to review the available evidence regarding the efficacy of reboxetine for treating ADHD. Method: The databases of Pubmed/Medline, Google scholar, SCOPUS and Web of Science were searched using the Keywords: "reboxetine", "ADHD" and "attention deficit hyperactivity disorder". The reference lists of the included studies were screened to find any possible other relevant articles. All the non-controlled and controlled clinical trials were included. Results: The current evidence mainly consists of un-controlled studies, such as case series. Only three of 33 studies were controlled clinical trials. They are from single sites and included a sub-sample of patients with ADHD. Conclusion: Non-controlled studies and controlled trials support the promising effect of reboxetine for treating ADHD in a sub-sample of patients that are without co-morbid psychiatric disorder and mental retardation. Reboxetine is tolerated well. However, more controlled trials are needed to reach any firm conclusion. © 2014 Informa Healthcare.

Javadpour A.,Research Center for Psychiatry and Behavioral science | Sahraian A.,Research Center for Psychiatry and Behavioral science | Rahman-Haghighi E.,Shiraz University of Medical Sciences
Shiraz E Medical Journal | Year: 2012

Background: Medical residents are a population who are at great risk to develop sleep disruption due to demanding clinical and academic duties. Knowing how much change in sleep wake pattern is associated with subsequent psychological distress could be useful to establish a systematic mental health program for medical residents. Method: a cross sectional study was conducted to explore the association between shift works and general health status of 128 medical residents. A self report sleep-wake questionnaire and general health questionnaire (GHQ) were used to test the pattern of sleep-wake and general health status respectively. Result: There was a significant correlation between sleep disruption and general health status of study sample (p=0.001).number of night shift was a predictor for general health among medical residents. Conclusion: sleep disruption due to shift work could be a predictor for mental morbidity. Reduce in night time shift among medical residents might prevent both physical and mental morbidity among them. © 2012, Shiraz E Medical Journal. All rights reserved.

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