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Cunha R.G.,Research and Development Institute
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference | Year: 2010

Cardiovascular diseases are the main causes of mortality, not only in Brazil, but around the world. The use of acupuncture as a complementary and alternative treatment for cardiovascular diseases has been suggested for animals as well as human beings. Possible advantages in using acupuncture are the low cost of treatment and low risks of collateral damage from a combination of acupuncture with other medical treatments. The purpose of this study is to assess the effect of traditional acupuncture with needles and laser acupuncture on arterial pressure and peripheral circulation of inferior limbs in patients with circulatory deficiency. Ten acupuncture points were stimulated in 40 individuals, being that 20 were stimulated by Aluminum gallium arsenide (AlGaAs) laser with emission in the red spectral region (650 nm) using an energy density of 2,4 J/cm2, and 20 were stimulated by systemic acupuncture needles. The analysis of peripheral circulation was performed based on the measurement of arterial pressure of the ankle and arms, using sphygmomanometer and Doppler equipment. The variance of the revascularization index of the laser acupuncture group was 0,057, and 0.030 for the needles group with p= 0,006. These results show that only those treated with laser acupuncture exhibit a significant increase in systolic pressure of their lower limbs, with a consequent improvement of the Revascularization Index, suggesting that different stimuli on acupuncture points generate different variations of peripheral resistance of lower limbs. is column.

Gavrilova V.,Ss. Cyril and Methodius University of Skopje | Kajdzanoska M.,Ss. Cyril and Methodius University of Skopje | Kajdzanoska M.,Research and Development Institute | Gjamovski V.,Ss. Cyril and Methodius University of Skopje | Stefova M.,Ss. Cyril and Methodius University of Skopje
Journal of Agricultural and Food Chemistry | Year: 2011

The phenolic profile of four blueberry varieties (Vaccinium corymbosum L., cv. Toro, Legacy, Duke and Bluecrop) and two varieties (Rosenthal and Rovada) of red currants (Ribes rubrum L.) and black currants (Ribes nigrum L.) cultivated in Macedonia have been analyzed using HPLC coupled to diode-array detection and tandem mass spectrometry with electrospray ionization. A complex profile of anthocyanins, flavonols, flavan-3-ols and hydroxycinnamic acid derivatives has been assayed in acetone-acetic acid (99:1, v/v) extracts. Anthocyanins comprised the highest content of total phenolic compounds in currants (>85%) and lower and variety dependent in blueberries (35-74%). Hydroxycinnamic acid derivatives comprised 23-56% of total phenolics in blueberries and 1-6% in currants. Chlorogenic acid was the major hydroxycinnamic acid in blueberries, only in the Legacy variety, two malonyl-caffeoylquinic acid isomers were major components. Flavonols, mainly quercetin and myricetin glycosides, were a minor group, but glucosides of laricitrin and syringetin were also detected in the blueberry varieties counting for 10-34% of total flavonols. From flavan-3-ols, catechin was detected in most samples; the dimer B2 was specific for blueberries whereas epigallocatechin was detected in currants. © 2011 American Chemical Society.

Chuengsamarn S.,Srinakharinwirot University | Chuengsamarn S.,Brigham and Womens Hospital | Rattanamongkolgul S.,Srinakharinwirot University | Luechapudiporn R.,Chulalongkorn University | And 3 more authors.
Diabetes Care | Year: 2012

OBJECTIVE - To assess the efficacy of curcumin in delaying development of type 2 diabetes mellitus (T2DM) in the prediabetic population. RESEARCH DESIGN AND METHODS - This randomized, double-blinded, placebo-controlled trial included subjects (n = 240) with criteria of prediabetes. All subjects were randomly assigned to receive either curcumin or placebo capsules for 9months. To assess the T2DM progression after curcumin treatments and to determine the number of subjects progressing to T2DM, changes in β-cell functions (homeostasis model assessment [HOMA]-β, C-peptide, and proinsulin/insulin), insulin resistance (HOMA-IR), anti-inflammatory cytokine (adiponectin), and other parameters were monitored at the baseline and at 3-, 6-, and 9-month visits during the course of intervention. RESULTS - After 9 months of treatment, 16.4% of subjects in the placebo group were diagnosed with T2DM, whereas none were diagnosed with T2DM in the curcumin-treated group. In addition, the curcumin-treated group showed a better overall function of β-cells, with higher HOMA-β (61.58 vs. 48.72; P < 0.01) and lower C-peptide (1.7 vs. 2.17; P < 0.05). The curcumin-treated group showed a lower level of HOMA-IR (3.22 vs. 4.04; P < 0.001) and higher adiponectin (22.46 vs. 18.45; P < 0.05) when compared with the placebo group. CONCLUSIONS - A 9-month curcumin intervention in a prediabetic population significantly lowered the number of prediabetic individuals who eventually developed T2DM. In addition, the curcumin treatment appeared to improve overall function of β-cells, with very minor adverse effects. Therefore, this study demonstrated that the curcumin intervention in a prediabetic population may be beneficial. © 2012 by the American Diabetes Association.

Yu J.,Research and Development Institute
Applied Mechanics and Materials | Year: 2014

Using the method of numerical simulations to study fluid dynamic characteristic of underwater vehicle rotary motion, using the N-S equation k-ω turbulence model description of the steady rotation of the vehicle, this paper studies the numerical calculation method of aircraft rotating derivative underwater, using UDF programming to produce a stable pressure rotation the flow field, set up an numerical turning basin. Then based on the simulation analysis the influence of the different radius of gyration and different angle of attack on the vehicle motion. © (2014) Trans Tech Publications, Switzerland.

Chon K.,Gwangju Institute of Science and Technology | Kim S.J.,Research and Development Institute | Moon J.,Machinery Metals and Construction Examination Bureau | Cho J.,Gwangju Institute of Science and Technology
Water Research | Year: 2012

The effects of the combined coagulation-disk filtration (CC-DF) process on the fouling characteristics and behavior caused by interactions between effluent organic matter (EfOM) and the membrane surfaces of the ultrafiltration (UF) and reverse osmosis (RO) membranes in a pilot plant for municipal wastewater reclamation (MWR) were investigated. The feed water from secondary effluents was treated by the CC-DF process used as a pretreatment for the UF membrane to mitigate fouling formation and the permeate from the CC-DF process was further filtered by two UF membrane units in parallel arrangement and fed into four RO modules in a series connection. The CC-DF process was not sufficient to mitigate biofouling but the UF membrane was effective in mitigating biofouling on the RO membrane surfaces. Fouling of the UF and RO membranes was dominated by hydrophilic fractions of EfOM (e.g., polysaccharide-like and protein-like substances) and inorganic scaling (e.g., aluminum, calcium and silica). The desorbed UF membrane foulants included more aluminum species and hydrophobic fractions than the desorbed RO membrane foulants, which was presumably due to the residual coagulants and aluminum-humic substance complexes. The significant change in the surface chemistry of the RO membrane (a decrease in surface charge and an increase in contact angle of the fouled RO membranes) induced by the accumulation of hydrophilic EfOM onto the negatively charged RO membrane surface intensified the fouling formation of the fouled RO membrane by hydrophobic interaction between the humic substances of EfOM with relatively high hydrophobicity and the fouled RO membranes with decreased surface charge and increased contract angle. © 2012 Elsevier Ltd.

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