CAMBRIDGE, MA, United States
CAMBRIDGE, MA, United States

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The disclosure relates to methods of improving safety, efficacy, or both, of pharmaceutically active aminothiol compounds by delivering them in a thiol-protected form and, preferably intracellularly.


Provided is an apparatus and technique for monitoring the drying, cure, film formation, and viscoelastic properties of liquids solidifiable liquid films, and the insitu measurement of viscoelastic properties of solidified films.


Patent
Res Group, Inc. and Soma | Date: 2015-07-27

A crushed bacterial cells can be obtained by culturing a gram-negative bacterium and physically crushing a body of the gram-negative bacterium, comprises all components including immunostimulatory components in the bacterial cells, and comprises LPSs having molecular weights of 20,000 or less as active ingredients. The crushed bacterial cells is effective as a health food, drug, skin-care product, bath agent, feedstuff for protecting crustaceans, shellfish, fish, poultry, farm animals and pet animals from infections, and a feed additive for growth promotion, and can provide an innate immunostimulatory substance derived from a gram-negative bacterial cells having infection-preventing effects and growth promoting effects, an inexpensive and practical microbial crushed bacterial cells, and a composition thereof.


Patent
The Government Of The United States and Res Group, Inc. | Date: 2016-08-12

A method for the prevention or treatment of human immunodeficiency virus infection by administering an effective amount of amifostine, phosphonol, or similar compound to an individual in need is provided.


A method and system platform for conducting mobile device market research into advertising effectiveness across varying media including mobile devices are disclosed. The method can include providing a previously defined data set comprising a list of mobile device respondents and related data. The method can include obtaining first party data for a subset of one or more mobile respondents from the list of mobile device respondents that participated in a predetermined activity. The method can include obtaining third party data for the subset of one or more mobile respondents that participated in the predetermined activity. The method can include correlating the first party data and the third party data. The method can include refining the previously defined data set based on the correlated first party data and third party data.


System and method for optimizing composition of a pool from which members are selected to serve on market research panels are described. In one embodiment, the system includes a database comprising a plurality of member profiles and survey data associated with the members and a datamart for periodically scanning the database to discover events and subsequently logging each of the discovered events in an event log. The system further includes an offense module for periodically evaluating the event log to determine whether one of the discovered events comprises an offense committed by one of the members and logging the offense in an offense log and an audit module for performing an audit of the one of the members and logging results of the audit in an audit log.


Patent
Res Group, Inc. | Date: 2016-09-14

Provided herein are topical formulations containing copper ions and methods of treating inflammatory, microbial, and arthritic conditions in various areas of the body using such formulations. Methods of treating osteoarthritis using topical copper ion treatments are provided. Methods of treating and preventing microbial infections using copper ion treatments are further provided, including methods of preventing biofilm. A topical treatment in its basic form comprises a biocompatible copper ion solution or suspension obtained by leaching of the copper ions from copper metal. The copper ion solution or suspension is combined with various carriers to form the copper ion treatment including creams, gels, lotions, foams, pastes, tampons, solutions, suppositories, body wipes, wound dressings, skin patches, and suture material. Methods of making the copper ion solution or suspension from solid copper metal in a biocompatible solution are also provided.


A method of matching a first entity to a second entity by evaluating Boolean expressions includes identifying a set of criteria vertices for a second entity vertex by traversing a graph database in a manner constrained to fact vertices identified for the second entity. The graph database relates fact vertices to the criteria vertices by edges corresponding to Boolean expressions for satisfying criteria for matching first entities to second entities. The method additionally includes selecting one of the first entities based on the criteria vertices of the set. The method further includes matching the first entity to the second entity based on the selection.


This disclosure is directed to artificially intelligent (AI) communication generation by traversing routes of a graph in a complex computing network. The intelligent communication generation is used for determining whether an input signal has certain desired signal attributes.


Copper ion treatments and methods of treatment are provided to treat various body conditions affecting the oral, respiratory and/or otic areas of the body. The copper ion treatments contain copper ions which bring about local and systemic therapeutic effects as a result of contacting anatomical tissue of the oral cavity, the nasal passages or ear canal. The copper ion treatments and methods involve copper ion-containing solutions, copper ion toothpaste and copper ion mouthwash. The copper ion-containing solutions can be delivered to the oral cavity by spraying or swabbing, can be delivered to the nostrils as spray, drops, or by swabbing, and can be delivered to the ear canal as spray, drops, or by swabbing. The copper ion toothpaste is used for brushing the teeth, and the copper ion mouthwash is used for rinsing the mouth.

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