Institute of Reproductive Genetics

Chicago, United States

Institute of Reproductive Genetics

Chicago, United States
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Verlinsky O.Yu.,Institute of Reproductive Genetics | Zhilenkova Yu.V.,North State Medical University | Kozlov A.V.,North State Medical University | Bessmeltsev S.S.,Federal Medical Biological Agency of Russia
Klinichescheskaya Laboratornaya Diagnostika | Year: 2017

The article presents the results of examination of 110 patients (57 males and 53 females aged from 2 to 58 years) with microcytic hypochromic anemia. The kit of laboratory markers comprised hematological parameters (MCV, Metier Index), biochemical (serum iron, ferritin), electrophoresis data (Hb, A2, Hb F) and molecular genetic analysis data (mutations of beta-globin gene). The application of this kit permitted to detected and to prove carriage of thalassemia mm 70 out of 110 patients with microcytic anemia. The proposed markers' kit can be applied in screening programs and in differential diagnostic of agents of beta-thalassemia and patients with iron-deficiency anemia.

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