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Redondo Beach, CA, United States

Grant
Agency: Department of Defense | Branch: Air Force | Program: SBIR | Phase: Phase II | Award Amount: 747.96K | Year: 2015

ABSTRACT: Redondo Optics Inc. (ROI) proposes to develop, ground and fly test, and deliver to the Air Force a low-cost next generation, aircraft ready, self-reference (T & P compensated) multi-point fiber optic oxygen sensor (FOxSense) network system for the real-time in-situ monitoring of the oxygen ullage environment for the closed-loop fuel tank inerting lightning protection warning system of tactical aircraft. The proposed next generation FOxSense system is based on the integration of ROIs proven and previously demonstrated state-of-the-art technologies: 1) the use of self-reference, temperature and pressure compensated, fuel inert fiber optic oxygen sensors 2) the use of fluorescence lifetime signal processing electronics; and 3) the use of advanced sensor calibration algorithms. In Phase II, the MIL-SPEC aircraft ready FOxSense oxygen network system will be qualified on a relevant tactical aircraft platform. In Phase IIB, ROI will engineer and produce a third generation fly qualifyable FOxSense oxygen monitoring system with a foot-print design that complies with the engineering requirements of the F-35 aircraft. In Phase III the FOxSense system will be transitioned to the Air Force for integration to the closed-loop OBIGS system of a tactical aircraft, and to the commercial avionics sector. BENEFIT: The self-reference multi-point FOxSense oxygen network system represents a new, innovative, and reliable solution for the in-situ measurement of the oxygen ullage fuel-tank environment of tactical jet fighter aircraft. Its aircraft ready compact package, lightweight, and power efficient multi-point FOxSense network system with build-in intrinsic T&P self-referencing, on-board embedded calibration, state-of-the-art data transmission, compatibility with existing fiber optic aircraft networks and cost affordable price makes it a very attractive solution for a large number of fuel-tank, cryogenic fuel-tanks, and cargo compartment fire prevention oxygen monitoring applications in aircraft, rotorcraft, space craft, submarines, and ships, as well as in the commercial medical, bio-tech, bio-remediation, nuclear, oil and gas, chemical and environment control industry.


Grant
Agency: National Aeronautics and Space Administration | Branch: | Program: SBIR | Phase: Phase I | Award Amount: 99.97K | Year: 2010

In-situ studies of the rocks, minerals, and soil on the Moon's surface provide a wealth of information during field geology and the mining phase for planetary resource identification. Sensitive optical spectroscopic instruments such as X-ray fluorescence spectrometers coupled with UV fluorescence spectroscopy is vital for lunar science. Many moon rock samples contain mineral oxides in the forms of Al2O3, TiO2, FeO, MnO, MgO, Cr2O3, Na2O and CaO. Further tests have shown that some of them exhibit fluorescence when exposed to UV light. Traditional UV fluorescence spectroscopy used in analysis of organic and inorganic materials utilizes power hungry, bulky lasers. Recently introduced UV-LED and semiconductor UV lasers with powers > 10 mW are small, reliable, and power efficient making them ideal for use in space exploration. Redondo Optics Inc, a world leader in design and development of fluorescent scientific instruments, proposes to develop a highly innovative and sensitive, light-weight, hand-held space qualified frequency domain fluorescence lifetime measurement system for NASA using heterodyne cross correlation technique. The instrument also includes an ultra miniature 340-780 nm spectrophotometer. The combined spectrometer utilizes lowest power COTS electronics components for fast and accurate estimation of fluorescence lifetimes to identify the rocks spectral signature.


Grant
Agency: Department of Defense | Branch: Office for Chemical and Biological Defense | Program: SBIR | Phase: Phase I | Award Amount: 99.84K | Year: 2010

Redondo Optics Inc. (ROI), a world leader in engineering and manufacturing of leading-edge nano-materials, optical sensors, fiber and integrated optics, and advanced photonics instrumentation proposes to develop and demonstrate an integrated electrophoretic nanofluidic biochip sensor platform for the accurate, reliable, and fast-throughput “label-less” THz spectroscopy finger printing of biological species and agents. Nanotechnology is emerging as the critical field for the next generation evolution of analytical biochip technology that will provide significant breakthroughs for affecting biomedicine. Miniaturization to the nanometer scale enables the probing of fundamental biological processes such as the epigenetic and genetic control factors of single molecules. Specifically, nanofluidic biochips can be use for the direct visualization of single DNA molecules. In Phase I, Redondo Optics will demonstrate an integrated THz nanofluidic biochip sensor platform that will enable the label-free fluid analysis of genetic material. The primary goal of this project is to validate and establish the use of the integrated THz nanofluidic biochip sensor platform as an analytical tool to allow the direct detection, identification, and classification of nucleic acids such as DNA and RNA in their native aqueous environment without the need of complex sample preparation procedures. In Phase II of this program, ROI will focus on the engineering development of a manufacturable optical nanolithography technology to enable the cost affordable production of disposable nanofluidic biochip arrays.


Grant
Agency: Department of Health and Human Services | Branch: National Institutes of Health | Program: SBIR | Phase: Phase I | Award Amount: 222.93K | Year: 2015

DESCRIPTION provided by applicant The goal of this proposal is to develop a convenient and portable electrophoretic plasmonic nanopore EPN GeneS tm DNA sequencing system that will enable the rapid reliable and automated DNA sequencing of an entire human genome within minutes at a cost $ that will revolutionize biological research and medicine The fundamental innovation is based on an electrophoretic plasmonic nanopore system nm use to slow and control the translocation rate of single stranded DNA molecules over wide ranges to enable accurate fast throughput massively parallel and real time single base pair optical recognition The propose EPN GeneS tm sequencer uses a cost effective and disposable fully integrated electrophoretic plasmonic nanopore EPN biochip that is interrogated via a custom andquot Smartandquot cell phone attachment device that integrates opto fluidics for electrophoretic fluid motion control standard multi wavelength semiconductor laser diodes pump andamp stokes to excite the vibrational modes of the translocating DNA and label free visualization of the scattered Raman spectral signature of the DNA base pair sequence using holographic filters integrated to the high resolution cell phone camera to acquire and process the sequence images via web connectivity resulting in a cost affordable $ DNA sequencing device In Phase I we will demonstrate the capability to control translocation rate of long DNA i e Lambda DNA molecule through the fractal plasmonic nanoporous structures to enable the real time recognition of the base pair DNA sequence using optical imaging techniques In Phase II we will optimize and integrate the EPN GeneS tm nanofluidic biochips to achieve a cost affordable $ high quality and reliable complete DNA sequencing device PUBLIC HEALTH RELEVANCE Complete sequencing of the human genome is this millenniumandapos s discovery goal Rapid advances in DNA sequencing is ushering the era of personal genomics to the point that every individual will have access to the complete DNA sequence of their genome for a modest cost In Phase I of this program ROI will demonstrate the capability to electrophoretically slow and control the translocation rate of long ssDNA through the fractal plasmonic nanoporous andquot roofandquot structure and identify in real time the translocating ssDNA single base pairs using SECARS imaging techniques If successful a complete sequence of a long ssDNA from a sample such as Lambda DNA will be determined In Phase II ROI will optimize and integrate the EPN GeneS tm nanofluidic biochips to a low cost opto fluidics prototype system that can transition to FDA approval and early entry to the next generation sequencing commercial market


Grant
Agency: Department of Defense | Branch: Office for Chemical and Biological Defense | Program: SBIR | Phase: Phase II | Award Amount: 749.48K | Year: 2011

Redondo Optics Inc. (ROI), proposes to develop and demonstrate a next generation integrated electrophoretic nanofluidic biochip (INTRay-Nanochip) sensor platform for the"label-less"THz spectroscopy finger printing of biological species and agents. In the proposed Phase II of this program, ROI will focus on the engineering development of a manufacturable optical nanolithography technology to enable the cost affordable production of disposable fully integrated electrophoretic nanofluidic biochip arrays, and to use the develop nanofluidic biochips for the extensive THz testing and assessment of the INTRay-Nanochip effectiveness for the THz fingerprinting detection, identification, and classification of biological materials and/or bio-agent targets. Nanotechnology is emerging as the critical field for the next generation evolution of analytical biochip technology that will provide significant breakthroughs for affecting biomedicine. At the completion of the Phase II program, ROI will have develop a manufacturable cost affordable nanolithography production of disposable INTRay-Nanochip arrays for the accurate label-less THz spectroscopy detection and identification of biological species such as DNA, RNA, proteins, and enzymes to enable the detection and identification of biological species. The range of commercial applications for the INTRay-Nanochip technology is very broad covering fields as different as pharmaceutical development, food testing, clinical diagnostics, forensics, environmental analysis, and biodefense.

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