RARS

Mahabubnagar, India
Mahabubnagar, India
SEARCH FILTERS
Time filter
Source Type

Govardhan G.,P.A. College | Reddy K.H.P.,P.A. College | Reddy D.M.,P.A. College | Sudhakar P.,P.A. College | And 2 more authors.
Ecology, Environment and Conservation | Year: 2017

The present investigation was carried out using 58 mungbean germplasm lines for assessing genetic variability under two environments viz., irrigated and moisture stress. Mean performance of the genotypes for most of the characters was higher in irrigated than moisture stress condition. Considerably high variability was observed for most of the yield attributes in E1 (irrigated) as well as E2 (moisture stress) conditions. A perusal of mean values revealed that the genotype MGG 390 in irrigated condition and CN 9058 in moisture stress condition were found to be best for seed yield per plant suggesting that these genotypes could be used as donors for yield improvement in their respective conditions. In both irrigated and moisture stress conditions, the check varieties viz., MGG 347, MGG 348, MGG 351 and LGG 460 exhibited consistent per se performance for most of the yield attributes and yield. Copyright © EM International.


Govardhan G.,P.A. College | Reddy K.H.P.,P.A. College | Reddy D.M.,P.A. College | Sudhakar P.,P.A. College | And 2 more authors.
Ecology, Environment and Conservation | Year: 2017

The present investigation was carried out on mungbean germplasm lines for assessing genetic variability under two environments viz., irrigated and moisture stress. Mean performance of the genotypes for most of the characters was higher in irrigated than moisture stress condition. Considerably high variability was observed for most of the yield and drought related traitss in E1 (irrigated) as well as E2 (moisture stress) conditions. The genotypes TLM 80 for SCMR, WGG 42 for specific leaf area, LM 97 for relative water content, LM 55 for relative injury and LM 12 for Chlorophyll stability index and MGG 390 for seed yield per plant registered superior performance in desirable direction under irrigated condition. The genotypes TLM 80 for SCMR, KM 8-651 for specific leaf area, LM 236 for relative water content, MGG 378 for relative injury, LM 12 for chlorophyll stability index and CN 9058 for seed yield per plant were found to be best under moisture stress condition. In both irrigated and moisture stress conditions, MGG 351 exhibited consistent per se performance for seed yield and four drought related traits SCMR, specific leaf area, relative water content and chlorophyll stability index. Hence, these genotypes could be used in hybridization programme to impart drought tolerance. Copyright © EM International.


Govardhan G.,Sv Agricultural College | Reddy K.H.P.,Sv Agricultural College | Reddy D.M.,Sv Agricultural College | Sudhakar P.,Sv Agricultural College | Reddy B.V.B.,R.A.R.S.
Ecology, Environment and Conservation | Year: 2017

The present investigation was undertaken to unravel the genetics of seed yield and yield attributes in three crosses (MGG 347 × MGG 351, MGG 351 × LGG 460 and LGG 460 × LGG 528) of mungbean under both irrigated and moisture stress conditions. Six basic generations viz., P1′ P2′ F1′ F2′ B1 and B2 of each cross were subjected to generation mean analysis. The per se performance was higher in irrigated condition compared to mat in moisture stress condition for most of the characters studied except days to days to 50 per cent flowering and days to maturity, suggesting variability among various generations under both the conditions. Further, the estimates of scaling tests (A, B, C and D) indicated appreciable amount of epistasis was present in majority of the characters of three crosses under both conditions. Duplicate type of epistasis was predominant for the inheritance of the same trait in different crosses and for different traits in the same cross. Hence, specific handling of individual cross in segregating generations would be advantageous for improvement of these traits and to modify the genetic architecture of mungbean for attaining higher yield under irrigated and/or moisture stress conditions. Copyright © EM International.


Sivajothi S.,C.V.Sc. | Rayulu V.C.,C.V.Sc. | Bhaskar Reddy B.V.,RARS | Malakondaiah P.,C.V.Sc. | And 2 more authors.
Journal of Parasitic Diseases | Year: 2016

The field isolates of Trypanosoma evansi was collected from the infected cattle and it was propagated in rats. Trypanosoma evansi parasites were separated from the blood of infected rats by using diethylaminoethyl cellulose column chromatography. Whole cell lysate antigen (WCL) was prepared from purified trypanosomes by ultrasonication and centrifugation. The prepared WCL antigen was further purified by 50 % ammonium sulphate precipitation. Protein concentration of WCL antigen of T. evansi was 60 mg/ml. Protein concentration was adjusted to 1.0 mg/ml in PBS, pH 8.0 and stored at −200 C. Polypeptide profiles of WCL antigen of T. evansi was determined by sodium dodecyl sulphate polyacrylamide gel electrophoresis. A total of eight polypeptide bands of the size ranging from 25 to 85 kDa in WCL antigen of T. evansi were obtained. Five prominent bands with molecular weight of 74, 60, 53, 42 and 37 kDa and three light bands with molecular weight of 85, 34 and 25 kDa were observed. © 2014, Indian Society for Parasitology.


Singh P.,MPUAT | Kubsad V.S.,UAS | Kalpana R.,TNAU | Alse U.N.,VNMKV | Sujathamma P.,RARS
Indian Journal of Agronomy | Year: 2015

Field experiments were conducted under All India Coordinated Sorghum Improvement Project (AICSIP) at 6 locations during rainy seasons of 2009 and 2010 in a split plot design having 3 fertility levels, viz., control (0:0:0 kg/ ha of N: P2 O5 :K2 O), recommended dose of nutrients-RDF (80:40:40 kg/ha of N: P2 O5 : K2 O) and 150% of RDF (120:60:60 kg/ha of N: P2 O5 : K2 O) in main-plots, while 8 sorghum cultivars including 3 hybrids (‘CSH 14’, ‘CSH 16’, ‘CSH 23’) and 5 varieties (‘SPV 462’, ‘CSV 15’, ‘CSV 17’, ‘CSV 23’, ‘SPV 1616’) constituted the sub-plot to find out their effects on productivity and nutrient-use efficiency in rainy-season grain sorghum [Sorghum bicolor (L.) Moench]. Results revealed that increasing levels of fertility up to 150% RDF significantly increased the grain yield (3.28 t/ha), nutrient uptake, net returns (25.97 ×103 /ha) and benefit: cost ratio (1.79) as compared to control. Hybrids produced 20.6% higher grain yield over varieties. Among hybrids ‘CSH 16’ (3.07 t/ha) and among varieties ‘SPV 462’ (2.56 t/ha) produced the maximum grain yields. The nutrient-use efficiency (NUE) was higher in hybrids (6.66 kg grain/kg NPK) than the varieties (5.54 kg grain/kg NPK). Increasing fertility levels from 100% RDF to 150% RDF increased the NUE of all the test hybrids, but decreased the efficiency of varieties except ‘CSV 17’. © 2015 Indian Society of Agronomy. All rights reserved.


DUBLIN--(BUSINESS WIRE)--Opsona Therapeutics Ltd (‘Opsona’), the innate immune drug development company focused on novel therapeutic approaches to treat oncology, autoimmune and other inflammatory diseases, today announces the preliminary results from its ongoing prospective, open label Phase I/II study being conducted with OPN-305 in second-line lower (Low and intermediate-1) risk myelodysplastic syndrome (MDS) which created interest when presented recently at the 58th Annual Meeting of the American Society of Hematology (ASH) in San Diego by Prof Garcia-Manero from the MD Anderson Cancer Center. OPN-305 is a novel proprietary humanized IgG4 monoclonal antibody (MAb) against Toll-Like Receptor 2 (TLR2), a key target within the innate immune system. Opsona has recently received orphan drug designation from the United States Food and Drug Administration for MDS. The study in patients with lower risk, red cell transfusion dependent, MDS who have failed hypomethylating agents (HMA) ± an erythropoiesis stimulating agent is ongoing in collaboration with MD Anderson Cancer Center in Houston USA with additional sites now being added in the USA. As of December 2016, 24 eligible patients have been enrolled, 11 at 5 mg dose and 13 at 10 mg/kg. A total of 15 (75%) patients are evaluable for response. Hematological improvement has been seen in 53% (8/15) with 3 (20%) patients achieving transfusion independence and of these 2/5 (40%) were receiving 10 mg/kg while on OPN-305 monotherapy. 12 patients remain on study. Median age was 72 years (range 42-87). Nine (43 %) patients were classified as Low risk and 15 (63%) as Intermediate-1 risk by IPSS. Thirteen patients (61%) had diploid cytogenetics, 8 (38%) RAEB,5 (23%) RCMD, 3 (14%) RA, 2 (10%) RARS, and 1 (4%) 5q-, RCMD-RS, CMML. The median number of prior HMA therapies was 2 (range 1-4) with a median duration of prior therapies from time of diagnosis to enrollment of 22.7 months (range 6.3-56.1). The median number of OPN-305 cycles administered is 5 (2-22) with 5 of 9 (55.5%) patients having received azacitidine add-back after 16 weeks of OPN-305 monotherapy. A total of 5 (29%) patients developed AEs related to OPN-305 all grade 1 with gastrointestinal disorders being the most frequent (23.5%). At this point, no significant drug related toxicity or unexpected infectious complications have been seen and combination with azacitidine has been well tolerated. To date three (20%) patients were taken off study due to progression to AML and 4 (27%) due to no response all at the 5 mg/kg dose. There is no evidence of treatment related anti-drug antibodies or statistically significant dynamic changes in cytokines in any of the patients. Myelodysplastic syndromes are a complex and heterogeneous group of bone marrow failure disorders characterized by ineffective hematopoiesis and poor prognosis. There is an urgent need for the development of well tolerated, novel therapies in the treatment of MDS which can delay progression, improve patient survival and quality of life and reduce the social and economic burden of transfusion dependence. Commenting on today’s announcement Mary Reilly VP Pharmaceutical Development & Operations said “OPN-305 data emerging in this heavily pre-treated group of patients is very encouraging, the unmet need for a safe and tolerable product for this patient population is significant and we are happy to be in collaboration with the MD Anderson Cancer Center one of the leading clinical center’s in this hematological area” Opsona is a leading immunology drug development company, focused on novel therapeutic approaches to key targets of the innate immune system associated with a wide range of major human diseases, including cancer, autoimmune and other inflammatory diseases. The company was founded in 2004 by three world-renowned immunologists at Trinity College, Dublin. Opsona has a strong international investor consortium including: Amgen Ventures, BB Biotech Ventures, EMBL Ventures, Enterprise Ireland, Fountain Healthcare Partners, Inventages Venture Capital, Novartis Venture Fund, Omnes Capital, Roche Venture Fund, Seroba Life Sciences, Shire and Sunstone Capital.


Saritha R.,Reg Agril Research Station | Dharma Reddy K.,RARS
Pestology | Year: 2013

Investigations were made to study the spatial distribution of whiteflies on Sunflower. Based on the variance-mean ratio, chi-square test and dispersion indices thrips have shown aggregated distribution and negative binomial model fitted the population pattern. Intraplant distribution studies indicated that the middle strata provided the most reliable estimate of the whitefly population on sunflower.


Saritha R.,Reg Agril Research Station | Dharma Reddy K.,RARS
Pestology | Year: 2013

Investigations were made to study the spatial distribution of leaf hoppers on Sunflower. Based on the variance-mean ratio, chi-square test and dispersion indices thrips have shown aggregated distribution and negative binomial model fitted the population pattern. Intraplant distribution studies indicated that the middle strata provided the most reliable estimate of the leaf hopper population on sunflower.


Gouri Shankar V.,RARS | Venkata Ramana Rao P.,APRRI and RARS | Bindu Priya P.,RARS | Nagesh Kumar M.V.,RARS | And 2 more authors.
Sabrao Journal of Breeding and Genetics | Year: 2013

Maintenance of genetic purity of a hybrid is essential to exploit its full potential. Genetic purity is generally assessed by conducting grow out test (GOT) where morphological and floral characters are analyzed, however results may be influenced by the environment. Further, it is expensive and time consuming. DNA based markers are rapid, reliable and cost effective for hybrid purity assessment. Several molecular markers such as RAPD, ISSR, AFLP, SSR, EST-SSR are being used for purity determination. Co-dominant markers are preferred over dominant markers as they reveal the heterozygous condition of the hybrid accurately. SSR markers are reliable markers for purity assessment. Because of inherent limitations of SSR markers, EST-SSR markers are considered as high quality markers as they give sharp, clear, and robust amplification. In this study, the parents (DPC-9, CS-1 and CS-18) of the two castor hybrids PCH-111 (DPC-9 × CS-1) and PCH-222 (DPC-9 × CS-18) were screened using 283 EST-SSR markers, nine markers showed polymorphism between DPC-9 and CS-1 and 10 between DPC-9 and CS-18 whereas 3 expressed polymorphism among 3 parents. As castor is highly cross pollinated crop and cytoplasmic male sterility system is not yet reported, the possible impurities in hybrid seed are selfing of female parent and pollination of female parent by unknown pollen parent. Selfed seed of female parent can be identified using single polymorphic marker, however contamination of female parent with unknown male parent can be detected reliably by using more number of polymorphic markers. © Society for the Advancement of Breeding Research in Asia and Oceania (SABRAO) 2013.


A variety with big boll hirsutum cotton coupled with high yield and desirable fiber quality parameters such as 2.5% span length, with optimum strength and micronaire value (fineness) ensures better income and premium price for quality in the market. MCU5, LRAS166, and other pure-bred varieties were cultivated in the upland cotton G hirsutum group, but these genotypes had smaller boll size of nearly 3.6 to 4.2 gram. Standard and uniform agronomic practices were adopted in the entire field to get uniform expression in all the plants. The upland cotton selection Hyps 156 has an attractive plant type with high combining ability for heterosis breeding programs. The seed Industry has been highly benefited by using this variety as male parent in heterosis breeding program and developed a large number of commercially marketed hybrids in conventional and subsequently as GMO cotton forms of the BG-I and BG-II types.

Loading RARS collaborators
Loading RARS collaborators