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Patent
Rapid Micro Biosystems | Date: 2015-04-24

The present invention features general-purpose microbiological growth media capable of supporting growth of microorganisms on membranes. The media contain casein digest, soybean digest, animal tissue digest, yeast extract, dextrose, a phosphate buffer, hemin, and L-cystine. The invention features an all-purpose microbiological growth media that can support the growth of anaerobes, molds, injured spores, and general aerobic bacteria to a greater extent than other media.


Patent
Rapid Micro Biosystems | Date: 2016-03-01

The invention enables efficient, rapid, and sensitive enumeration of living cells by detecting microscopic colonies derived from in situ cell division using large area imaging. Microbial enumeration tests based on the invention address an important problem in clinical and industrial microbiologythe long time needed for detection in traditional testswhile retaining key advantages of the traditional methods based on microbial culture. Embodiments of the invention include non-destructive aseptic methods for detecting cellular microcolonies without labeling reagents. These methods allow for the generation of pure cultures which can be used for microbial identification and determination of antimicrobial resistance.


This report studies Microbial Detection System in Global market, especially in North America, Europe, China, Japan, Southeast Asia and India, focuses on top manufacturers in global market, with production, price, revenue and market share for each manufacturer, covering  BioMerieux  ThermoFisher Scientific  EMD Millipore  MOCON Inc.  Celsis  Particle Measuring Systems (PMS)  Pharmtech  BioVigilant  Rapid Micro Biosystems Inc.  Charm Sciences  TAILIN  Molecular Devices  Merck Millipore  QIKUN SCIENCE  Instant Bioscan  BioLumix  Analytik Jena  Vitek  MicroBio  Promega Market Segment by Regions, this report splits Global into several key Regions, with production, consumption, revenue, market share and growth rate of Microbial Detection System in these regions, from 2011 to 2021 (forecast), like  North America  Europe  China  Japan  Southeast Asia  India Split by product type, with production, revenue, price, market share and growth rate of each type, can be divided into  Type I  Type II  Type III Split by application, this report focuses on consumption, market share and growth rate of Microbial Detection System in each application, can be divided into  Application 1  Application 2  Application 3 Global Microbial Detection System Market Research Report 2016  1 Microbial Detection System Market Overview  1.1 Product Overview and Scope of Microbial Detection System  1.2 Microbial Detection System Segment by Type  1.2.1 Global Production Market Share of Microbial Detection System by Type in 2015  1.2.2 Type I  1.2.3 Type II  1.2.4 Type III  1.3 Microbial Detection System Segment by Application  1.3.1 Microbial Detection System Consumption Market Share by Application in 2015  1.3.2 Application 1  1.3.3 Application 2  1.3.4 Application 3  1.4 Microbial Detection System Market by Region  1.4.1 North America Status and Prospect (2011-2021)  1.4.2 Europe Status and Prospect (2011-2021)  1.4.3 China Status and Prospect (2011-2021)  1.4.4 Japan Status and Prospect (2011-2021)  1.4.5 Southeast Asia Status and Prospect (2011-2021)  1.4.6 India Status and Prospect (2011-2021)  1.5 Global Market Size (Value) of Microbial Detection System (2011-2021) 7 Global Microbial Detection System Manufacturers Profiles/Analysis  7.1 BioMerieux  7.1.1 Company Basic Information, Manufacturing Base and Its Competitors  7.1.2 Microbial Detection System Product Type, Application and Specification  7.1.2.1 Type I  7.1.2.2 Type II  7.1.3 BioMerieux Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.1.4 Main Business/Business Overview  7.2 ThermoFisher Scientific  7.2.1 Company Basic Information, Manufacturing Base and Its Competitors  7.2.2 Microbial Detection System Product Type, Application and Specification  7.2.2.1 Type I  7.2.2.2 Type II  7.2.3 ThermoFisher Scientific Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.2.4 Main Business/Business Overview  7.3 EMD Millipore  7.3.1 Company Basic Information, Manufacturing Base and Its Competitors  7.3.2 Microbial Detection System Product Type, Application and Specification  7.3.2.1 Type I  7.3.2.2 Type II  7.3.3 EMD Millipore Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.3.4 Main Business/Business Overview  7.4 MOCON Inc.  7.4.1 Company Basic Information, Manufacturing Base and Its Competitors  7.4.2 Microbial Detection System Product Type, Application and Specification  7.4.2.1 Type I  7.4.2.2 Type II  7.4.3 MOCON Inc. Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.4.4 Main Business/Business Overview  7.5 Celsis  7.5.1 Company Basic Information, Manufacturing Base and Its Competitors  7.5.2 Microbial Detection System Product Type, Application and Specification  7.5.2.1 Type I  7.5.2.2 Type II  7.5.3 Celsis Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.5.4 Main Business/Business Overview  7.6 Particle Measuring Systems (PMS)  7.6.1 Company Basic Information, Manufacturing Base and Its Competitors  7.6.2 Microbial Detection System Product Type, Application and Specification  7.6.2.1 Type I  7.6.2.2 Type II  7.6.3 Particle Measuring Systems (PMS) Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.6.4 Main Business/Business Overview  7.7 Pharmtech  7.7.1 Company Basic Information, Manufacturing Base and Its Competitors  7.7.2 Microbial Detection System Product Type, Application and Specification  7.7.2.1 Type I  7.7.2.2 Type II  7.7.3 Pharmtech Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.7.4 Main Business/Business Overview  7.8 BioVigilant  7.8.1 Company Basic Information, Manufacturing Base and Its Competitors  7.8.2 Microbial Detection System Product Type, Application and Specification  7.8.2.1 Type I  7.8.2.2 Type II  7.8.3 BioVigilant Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.8.4 Main Business/Business Overview  7.9 Rapid Micro Biosystems Inc.  7.9.1 Company Basic Information, Manufacturing Base and Its Competitors  7.9.2 Microbial Detection System Product Type, Application and Specification  7.9.2.1 Type I  7.9.2.2 Type II  7.9.3 Rapid Micro Biosystems Inc. Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.9.4 Main Business/Business Overview  7.10 Charm Sciences  7.10.1 Company Basic Information, Manufacturing Base and Its Competitors  7.10.2 Microbial Detection System Product Type, Application and Specification  7.10.2.1 Type I  7.10.2.2 Type II  7.10.3 Charm Sciences Microbial Detection System Production, Revenue, Price and Gross Margin (2015 and 2016)  7.10.4 Main Business/Business Overview  7.11 TAILIN  7.12 Molecular Devices  7.13 Merck Millipore  7.14 QIKUN SCIENCE  7.15 Instant Bioscan  7.16 BioLumix  7.17 Analytik Jena  7.18 Vitek  7.19 MicroBio  7.20 Promega


London R.,Rapid Micro Biosystems | Schwedock J.,Rapid Micro Biosystems | Sage A.,Rapid Micro Biosystems | Valley H.,Rapid Micro Biosystems | And 4 more authors.
PLoS ONE | Year: 2010

Background: The power and simplicity of visual colony counting have made it the mainstay of microbiological analysis for more than 130 years. A disadvantage of the method is the long time required to generate visible colonies from cells in a sample. New rapid testing technologies generally have failed to maintain one or more of the major advantages of culture-based methods. Principal Findings: We present a new technology and platform that uses digital imaging of cellular autofluorescence to detect and enumerate growing microcolonies many generations before they become visible to the eye. The data presented demonstrate that the method preserves the viability of the microcolonies it detects, thus enabling generation of pure cultures for microbial identification. While visual colony counting detects Escherichia coli colonies containing about 5×106 cells, the new imaging method detects E. coli microcolonies when they contain about 120 cells and microcolonies of the yeast Candida albicans when they contain only about 12 cells. We demonstrate that digital imaging of microcolony autofluorescence detects a broad spectrum of prokaryotic and eukaryotic microbes and present a model for predicting the time to detection for individual strains. Results from the analysis of environmental samples from pharmaceutical manufacturing plants containing a mixture of unidentified microbes demonstrate the method's improved test turnaround times. Conclusion: This work demonstrates a new technology and automated platform that substantially shortens test times while maintaining key advantages of the current methods. © 2010 London et al.


Patent
Rapid Micro Biosystems | Date: 2010-03-19

The invention enables efficient, rapid, and sensitive enumeration of living cells by detecting microscopic colonies derived from in situ cell division using large area imaging. Microbial enumeration tests based on the invention address an important problem in clinical and industrial microbiologythe long time needed for detection in traditional testswhile retaining key advantages of the traditional methods based on microbial culture. Embodiments of the invention include non-destructive aseptic methods for detecting cellular microcolonies without labeling reagents. These methods allow for the generation of pure cultures which can be used for microbial identification and determination of antimicrobial resistance.


Patent
Rapid Micro Biosystems | Date: 2012-11-07

The invention provides a device for growing cellsreferred to as a cassette. The cell culturing device includes a housing that contains a lid having an optically clear window; a fluid distribution channel; a sample injection port fluidically connected to the fluid distribution channel; a base housing a porous media pad; and a media injection port fluidically connected to the media pad. The lid mates to the base to form a sterile seal; the fluid distribution channel is disposed over the media pad, which is viewable through the optical window; and sample fluid introduced into the fluid distribution channel is distributed evenly to the media pad, e.g., via a plurality of channels. The invention also provides kits that include cassettes of the invention and a tube set.


PubMed | Rapid Micro Biosystems
Type: Journal Article | Journal: PDA journal of pharmaceutical science and technology | Year: 2015

New recommendations for the validation of rapid microbiological methods have been included in the revised Technical Report 33 release from the PDA. The changes include a more comprehensive review of the statistical methods to be used to analyze data obtained during validation. This case study applies those statistical methods to accuracy, precision, ruggedness, and equivalence data obtained using a rapid microbiological methods system being evaluated for water bioburden testing. Results presented demonstrate that the statistical methods described in the PDA Technical Report 33 chapter can all be successfully applied to the rapid microbiological method data sets and gave the same interpretation for equivalence to the standard method. The rapid microbiological method was in general able to pass the requirements of PDA Technical Report 33, though the study shows that there can be occasional outlying results and that caution should be used when applying statistical methods to low average colony-forming unit values.Prior to use in a quality-controlled environment, any new method or technology has to be shown to work as designed by the manufacturer for the purpose required. For new rapid microbiological methods that detect and enumerate contaminating microorganisms, additional recommendations have been provided in the revised PDA Technical Report No. 33. The changes include a more comprehensive review of the statistical methods to be used to analyze data obtained during validation. This paper applies those statistical methods to analyze accuracy, precision, ruggedness, and equivalence data obtained using a rapid microbiological method system being validated for water bioburden testing. The case study demonstrates that the statistical methods described in the PDA Technical Report No. 33 chapter can be successfully applied to rapid microbiological method data sets and give the same comparability results for similarity or difference as the standard method.


Patent
Rapid Micro Biosystems | Date: 2013-04-16

The invention features devices and kits for capturing and culturing microorganisms (e.g., bacteria, fungi, or protists) and methods of using the devices and kits to detect microorganisms in environmental and other samples. The device includes a nutrient media having a flat growth area on which microorganisms can grow. Samples are collected by contacting the device with any environmental sample, e.g., rolling device on a work surface or exposing device to air, or by filtering a sample through a membrane. Microorganisms deposited on the membrane derive nutrients from the underlying media and grow into colonies that can then be detected using methods known in the art. The detected colonies can be imaged digitally or with film.


News Article | October 27, 2016
Site: co.newswire.com

Rapid Micro Biosystems, a leading provider of automated, non-destructive, rapid microbial detection, is pleased to announce the addition of Natale (Nat) Ricciardi to its Board of Directors.

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