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Kākināda, India

Nagendra Prasad B.,Rangaraya Medical College | Bhaskar K.,Sv Medical College
Journal of South India Medicolegal Association

The determination of an age in adolescents has played an important role in Medico-legal work. Identification of the age is required in the Criminal Justice delivery System like child labour, rape, kidnapping, mass disasters, marriage, prostitution and murder cases especially the skeleton remains are available for analysis. It is important in connection with the question of criminal responsibility of several different cases and awarding of judicial punishment etc. The present investigation is the estimation of age in adolescents i.e., both boys and girls through fusion of Ossification Centers of ones of elbow joints examination by Radiological Technique (X-rays) in the age group of 14-17 years in 50 boys and 50 girls in Tirupati region. © 2016 South India Medico-Legal Association. All rights reserved. Source

Bhaskar K.,Sv Medicalcollege | Nagendraprasad B.,Rangaraya Medical College
Indian Journal of Forensic Medicine and Toxicology

“Caution is advised while decontaminating a victim of poisoning. Over enthusiasm may result in eliminating the patient, not the poison!” -John Morrision Poisoning has been known to mankind since time immemorial and the study of various poisons and their eff ects has always fascinated mankind. References to poisons and various instances of poisoning are available in Indian Shastras, Egyptian Papyri and Sumerian writings. Since then many substances considered advantages and disadvantages in the form of food or poisons have been discovered. Those substances which are used unfortunately to take away the man’s life or cause ill health have been changing. Some of the great persons who were poisoned to death are Chatrapati Shivaji Maharaj,2-3 whose bed was poisoned, Socrates, who was made to drink Hemlock (Conium maculatum) and Rasputin who was poisoned with cyanide and then shot.Aluminum phosphide poisoning, a rodenticide is also posing a formidable challenge and is on the way for taking the number one position. As poisoning trends go on changing, it is necessary to know the poisoning trends from time to time. © 2015, Indian Journal of Forensic Medicine and Toxicology. All rights reserved. Source

Vupputuri M.,Konaseema Institute of Medical science | Kandepu M.,Rangaraya Medical College | Devireddy H.R.,Devireddy Diabetes and Hormone Center
Indian Journal of Pediatrics

5α-reductase (5α-R) deficiency is an important cause of ambiguious genitalia in genetic males; however therapeutic experience in literature is limited. In this report authors describe a child with 46 XY Disorder of Sexual Differentiation (DSD), due to 5α-reductase deficiency, who was managed with Dihydrotestosterone (DHT) gel. © 2013 Dr. K C Chaudhuri Foundation. Source

Reddi B.R.,Rangaraya Medical College
Indian Journal of Surgery

A clinical observation to diagnose parotid hemangioma is presented in this article. A hemangioma can be made to distend by blocking its venous outflow. If a distended hemangioma is located within the parotid gland, it stretches the parotid capsule. Thus application of pressure over parotid venous outflow causes the hemangioma to bulge, thereby stretching the parotid capsule. It makes the outline of the gland clinically apparent. This observation is useful to differentiate a hemangioma present in the parotid gland from one that is placed outside the gland like an intramuscular hemangioma of the masseter muscle or internal jugular phlebectasia. © Association of Surgeons of India 2012. Source

Dwarampudi G.S.,Rangaraya Medical College
International Journal of Pharma and Bio Sciences

Neonatal hyperbilirubinemia resulting in clinical jaundice is a common problem during the first weeks of neonates life. Most common cause of hyperbilirubinemia in neonates is physiological hyperbilirubinemia. Although physiological hyperbilirubinemia is 100% curable;Fallow up and the early treatment has become difficult due to early discharge from the hospital. Physiological hyperbilirubinemia results from immature liver cell having very low uridine diphospho glucuronosyl transferase activity compared to mature hepatocyte, low concentration of Bilirubin binding ligand Albumin, and higher volume of short life erythrocytes in the circulation. Studies strongly argues for the primacy of bilirubin in the etiology of kernicterus. present study: estimation of neonatal cord blood albumin and bilirubin levels and assessing their reliability with the third day neonatal peripheral venous sample bilirubin levels. To assess the reliability of cord blood albumin and bilirubin levels in early prediction of Hyperbilirubinemia in neonates. Present study was conducted on 70 neonates (term & preterm) whose cord blood was estimated for albumin and bilirubin levels by dye binding method and modified dimethylsulfoxide methods respectively. Incidence of Hyperbilirubinemia is confirmed by estimating peripheral venous blood bilirubin levels by DMSO method on day third of the neonate . Frequency of hyperbilirubinemia in neonates in our center at term is 52 % and in pre-tem is 70% 10,11. Cord blood albumin level of < 2.8 gm/dl has a sensitivity of 74% and specificity of 88%9,13 and Cord bilirubin level >2mg/dl has 70% sensitivity and 90%specificity 7, 9, in predicting the risk of neonatal hyperbilirubinemia. Present study supports that Cord blood albumin and bilirubin levels are reliable in predicting development of hyperbilirubinemia. This study also supports gestational age has impact in developing hyperbilirubinemia. By early detection of hyperbilirubinemia treatment option will be simple phototherapy which prevent neonate from having unnecessary transfusions. Recommendations: Hence it is recommended to include estimation of cord blood albumin and bilirubin levels as a routine investigation for the neonates to prevent the dangerous consequences of neonatal hyperbilirubinemia like kernicterus. ABREVATIONs: CSA: Cord serum Albumin, TB: Total bilirubin, UB: Un conjugated bilirubin. Source

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