Rajah Serfoji Government College

Thanjāvūr, India

Rajah Serfoji Government College

Thanjāvūr, India
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Rajarajan K.,Rajah Serfoji Government College | Anbarasan K.,Rajah Serfoji Government College | Samu Solomon J.,TBML College | Madhurambal G.,ADM College for women
Journal of Chemical and Pharmaceutical Research | Year: 2012

Single crystals of Lead(II)nitrate doped Histidine Picrate crystal has been grown successfully by solution growth method from its aqueous solution. The grown crystals have been subjected to X-ray diffraction (XRD) studies to identify the morphology and structure. The FTIR study reveals bonding interaction of PbNO3 and Histidine in the crystal. The NLO property of the crystals has been confirmed.

Rajesh N.,Rajah Serfoji Government College
International Journal of Applied Engineering Research | Year: 2015

In this paper, G-semiclosed sets and G-semiopen sets are used to define and investigate a new class of functions called contra-G-semicontinuous functions in grill topological spaces. © Research India Publications.

Krishnamoorthy P.,Rajah Serfoji Government College
Indian Journal of Natural Products and Resources | Year: 2011

Carcinogens, 0.06% of p-dimethylaminoazobenzene (p-DAB) with feed and 0.05% phenobarbital (PB) with water were orally administered to rats for 60 days. Powdered endocarps of Ziziphus mauritiana Lam. were extracted with two different solvents, ethanol and ethylacetate. Oral LD 50 of the two extracts were estimated to be 1200.24 mg/kg body weight. Preliminary phytochemical studies of the extracts revealed the presence of triterpenoids, reducing sugars, sugars, alkaloids, phenolics, catechins, flavonoids, saponins, tannins and amino acids. Experimental rats were orally co-fed with the ethanol extract (at two different doses of 300 and 150 mg/kg/bw) and carcinogens. Comparatively, other group was co-fed with ethylacetate extract (at two different doses of 300 and 150mg/kg/b.w) with carcinogens. Antioxidant biochemical studies revealed that ethanol extract was more effective than ethylacetate extract. Histological studies revealed a distinct hepatoprotective effect of Z. mauritiana endocarps (with kernel) at 300 mg/kg body weight of ethanol extract, which sustained the normal architecture of liver cells from p-Dimethtylaminoazobenzene and phenobarbitol induced toxicity, whereas severe damages were evident in the hepatocarcinoma induced rats.

Baca M.,Technical University of Košice | Jendrol S.,University of P.J. Šafarik | Kathiresan K.,AYYA Nadar Janaki Ammal College | Muthugurupackiam K.,Rajah Serfoji Government College
Applied Mathematics and Information Sciences | Year: 2015

A face irregular entire k-labeling j ϕ: V υE υF →{1,2,., k} of a 2-connected plane graph G = (V, E, F) is a labeling of vertices, edges and faces of G in such a way that for any two different faces f and g their weights wϕ (f) and wϕ (g) are distinct. The weight of a face f under a k-labeling ϕ is the sum of labels carried by that face and all the edges and vertices incident with the face. The minimum k for which a plane graph G has a face irregular entire k-labeling is called the entire face irregularity strength. We investigate a face irregular entire labeling as a modification of the well-known vertex irregular and edge irregular total labelings of graphs. We obtain some estimations on the entire face irregularity strength and determine the precise values for graphs from three families of plane graphs. © 2015 NSP.

Harikrishnan R.,Jeju National University | Kim D.-H.,Jeju National University | Hong S.-H.,Jeju National University | Mariappan P.,Rajah Serfoji Government College | And 2 more authors.
Fish and Shellfish Immunology | Year: 2012

The immunomodulatory effect of Siegesbeckia glabrescens extract-supplementation diets on innate immune response and disease resistance of kelp grouper, Epinephelus bruneus against . Vibrio parahaemolyticus at weeks 1, 2, and 4 is reported. The serum lysozyme activity was significantly enhanced with any enriched diet from weeks 1-4 when compared to control diet (0%). The alternative complement haemolytic activities significantly were enhanced with all enriched diets on weeks 2 and 4 whereas the cellular reactive oxygen species (ROS) was significantly enhanced only with 1.0% and 2.0% diets. The reactive nitrogen intermediate (RNI) value was significantly enhanced with any enriched diet on weeks 2 and 4, but on first week it did not differ from control. The myeloperoxidase (MPO) production significantly increased with 1.0% and 2.0% diets from second week onwards; with other enriched diets the increase manifested on fourth week; but during first week it did not vary from that of the control with any enriched diet. The protection in terms of cumulative mortality was the least being 25% and 20% when fed with 1.0% and 2.0% diets. The present results indicate that feeding kelp grouper with S. glabrescens extract enriched diet at 1.0% and 2.0% levels significantly enhance the immunological parameters, increase the disease resistance and minimize the cumulative mortality in E. bruneus against V. parahaemolyticus. © 2012 Elsevier Ltd.

Muthukrishnan S.,Bharathidasan University | Bhakya S.,Rajah Serfoji Government College | Senthil Kumar T.,Bharathidasan University | Rao M.V.,Bharathidasan University
Industrial Crops and Products | Year: 2015

Leaf extract of in vitro raised plants of Ceropegia thwaitesii was assessed for the green synthesis of silver nanoparticles (AgNPs). The biosynthesized AgNPs were authorized by UV-vis spectrophotometer with surface plasmon resonance at 430. nm. The scanning electron microscope (SEM), dynamic light scattering (DLS) analysis confirmed the particle size 100. nm, and X-ray diffraction (XRD) confirmed the crystalline character of AgNPs. Further, Fourier transform infrared (FTIR) authorized the presence of triterpenoids and methoxy groups played an important reduction role in the synthesis process. It shows the significant antibacterial efficacy against Salmonella typhi, Shigella flexneri, Klbsiella pneumonia, Eschericia coli and others species. From the results, it is suggested that green synthesized AgNPs could be used effectively in future biomedical engineering. © 2014 Elsevier B.V.

Ali R.M.,Universiti Sains Malaysia | Ravichandran V.,University of Delhi | Seenivasagan N.,Rajah Serfoji Government College
Journal of the Franklin Institute | Year: 2010

Differential subordination and superordination results are obtained for analytic functions in the open unit disk which are associated with the DziokSrivastava linear operator. These results are obtained by investigating appropriate classes of admissible functions. Sandwich-type results are also obtained. © 2010 The Franklin Institute. Published by Elsevier Ltd. All rights reserved.

Kuppusamy S.,Apex laboratories private Ltd | Karuppaiah J.,Rajah Serfoji Government College
Asian Pacific Journal of Tropical Disease | Year: 2012

Objective: The present study demonstrated the antioxidant and cytotoxic efficacy of chitosan by evaluating cell viability in T24 human bladder cancer cell line and benzidine induced bladder cancer. The chemo preventive effects of the chitosan were evaluated in Swiss albino mice using 16 weeks medium term model of benzidine induced bladder cancer. Methods: Treatment of T24 cells with increasing concentration of chitosan led to a concentration dependent decrease in cell migration by MTT assay. The enzymic and non enzymic antioxidants were measured. Results: Bladder cancer was induced twice weekly through oral incubation of benzidine for 4 weeks. The oral administration of chitosan (100mg KG-1 body wt) showed a significant increase in antioxidant enzymes like Super oxide dismutase (SOD), Glutathione peroxidase (GPx), Glutathione reductase (GR), Catalase (CAT) and non-enzymic antioxidants like reduced Glutathione (GSH), vitamin C and vitamin E when compared to benzidine treated groups. The effect is more pronounced in pretreatment regime than in the post treatment regime. The levels of lipid peroxidation were significantly decreased in the chitosan treated regimes. Conclusions: The present study reveals that chitosan has antioxidant and cytotoxic effects on benzidine induced bladder cancer and T24 human bladder cancer cell line. © 2012 Asian Pacific Tropical Medicine Press.

Veerappan R.,Rajah Serfoji Government College | Senthilkumar R.,Nizam College
International Journal of Nutrition, Pharmacology, Neurological Diseases | Year: 2015

Objectives: The study seeks to evaluate the effect of chrysin; a natural, biologically active compound extracted from plants, honey or propolis, on the tissues and circulatory antioxidant status and lipid peroxidation in Nω-nitro-l-arginine methyl ester (L-NAME) induced hypertensive rats. Materials and Methods: Male albino rats were divided into four groups. Control (Group I) and chrysin supplementation of the control (Group II) received normal diet. Groups III and IV received L-NAME (40 mg/kg B.W). Groups II and IV received chrysin (25 mg/kg B.W) dissolved in 0.2% dimethylsulfoxide solution after the 4 th week. Results and Discussion: The results showed significantly elevated levels of tissue and circulatory thiobarbituric acid reactive substances, conjugated dienes and lipid hydroperoxides, and significantly lowered enzymic and non-enzymic antioxidant activity of superoxide dismutase, catalase, glutathione peroxidase, reduced glutathione, vitamin C and vitamin E in L-NAME-induced hypertensive rats compared with those in control group. From chrysin administration to rats with L-NAME-induced hypertension leads to tissue damage which significantly decreases the levels of thiobarbituric acid reactive substances, lipid hydroperoxides and conjugated dienes, and significantly elevates the activity of superoxide dismutase, catalase, glutathione peroxidase, reduced glutathione, vitamin C and vitamin E in the tissues and circulation compared with those on the unsupplemented L-NAME induced hypertensive group. Conclusions: Chrysin offers protection against free radical-mediated oxidative stress in rats with L-NAME-induced hypertension. © 2015, Wolters Kluwer - Medknow Publications. All rights reserved.

Ramanathan V.,Rajah Serfoji Government College | Rajagopal S.,Rayalaseema University
American Journal of Biochemistry and Molecular Biology | Year: 2016

Background: It is investigated to deduct the action of chrysin on the cardiovascular risk of NT-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats. The L-NAME is a non-specific Nitric Oxide (NO) synthase inhibitor, commonly used for the induction of NO-deficient hypertension. Materials and Methods: The L-NAME (40 mg kg-1 b.wt.) was dissolved in drinking water and was given to rats at an interval of 24 h for 8 weeks. Chrysin were administered orally once in a day in the morning for 4 weeks. The compound was suspended in 2% dimethyl sulfoxide solution and fed by incubation. After 8th week morning the animals were sacrificed by cervical dislocation and done with lipid profiles parameters. Results: Administration of L-NAME significantly increased the mean arterial pressure and heart rate compared to control rats, while treatment with chrysin significantly reduced the mean arterial pressure and heart rate compared to hypertensive rats. When L-NAME-induced hypertensive rats compared with the control, an extend sign were seen in the factors such as the concentrations of plasma, tissue (liver and kidney) lipids, lipoproteins and hepatic marker enzymes and a decrement were noted in the concentration of high-density lipoprotein cholesterol. A recent of hyperlipidemia resulted from oral prescription of chrysin. Conclusion: Thus, chrysin gives protection against hyperlipidemic and hepatic damage in rats with L-NAME induced hypertension. © 2016 Veerappan Ramanathan and Senthilkumar Rajagopal.

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