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Ali R.M.,Universiti Sains Malaysia | Ravichandran V.,University of Delhi | Seenivasagan N.,Rajah Serfoji Government College
Journal of the Franklin Institute

Differential subordination and superordination results are obtained for analytic functions in the open unit disk which are associated with the DziokSrivastava linear operator. These results are obtained by investigating appropriate classes of admissible functions. Sandwich-type results are also obtained. © 2010 The Franklin Institute. Published by Elsevier Ltd. All rights reserved. Source

Rajesh N.,Rajah Serfoji Government College
International Journal of Applied Engineering Research

In this paper, G-semiclosed sets and G-semiopen sets are used to define and investigate a new class of functions called contra-G-semicontinuous functions in grill topological spaces. © Research India Publications. Source

Veerappan R.,Rajah Serfoji Government College | Senthilkumar R.,Nizam College
International Journal of Nutrition, Pharmacology, Neurological Diseases

Objectives: The study seeks to evaluate the effect of chrysin; a natural, biologically active compound extracted from plants, honey or propolis, on the tissues and circulatory antioxidant status and lipid peroxidation in Nω-nitro-l-arginine methyl ester (L-NAME) induced hypertensive rats. Materials and Methods: Male albino rats were divided into four groups. Control (Group I) and chrysin supplementation of the control (Group II) received normal diet. Groups III and IV received L-NAME (40 mg/kg B.W). Groups II and IV received chrysin (25 mg/kg B.W) dissolved in 0.2% dimethylsulfoxide solution after the 4 th week. Results and Discussion: The results showed significantly elevated levels of tissue and circulatory thiobarbituric acid reactive substances, conjugated dienes and lipid hydroperoxides, and significantly lowered enzymic and non-enzymic antioxidant activity of superoxide dismutase, catalase, glutathione peroxidase, reduced glutathione, vitamin C and vitamin E in L-NAME-induced hypertensive rats compared with those in control group. From chrysin administration to rats with L-NAME-induced hypertension leads to tissue damage which significantly decreases the levels of thiobarbituric acid reactive substances, lipid hydroperoxides and conjugated dienes, and significantly elevates the activity of superoxide dismutase, catalase, glutathione peroxidase, reduced glutathione, vitamin C and vitamin E in the tissues and circulation compared with those on the unsupplemented L-NAME induced hypertensive group. Conclusions: Chrysin offers protection against free radical-mediated oxidative stress in rats with L-NAME-induced hypertension. © 2015, Wolters Kluwer - Medknow Publications. All rights reserved. Source

Anbuselvan D.,Bharathiar University | Anbuselvan D.,Rajah Serfoji Government College | Muthukumaran S.,Government Arts College
Optical Materials

In the present study Ni-doped ZnO and Ni, Cu-doped ZnO nanoparticles were successfully synthesized by co-precipitation method. Structural studies confirmed the dominant presence of hexagonal wurtzite ZnO phase at lower Cu concentration and CuO phase was observed at higher Cu (Cu = 5%) concentration. The existence of Cu2+ ions were dominant at Cu ≤ 3% (responsible for lattice shrinkage) and the presence of Cu+ ions were dominant at Cu > 3% (responsible for lattice expansion). The change in UV-visible absorption and energy gap were discussed by secondary phase generation and charge carrier density. The low absorption loss and high transmittance at Cu = 3% doped samples is used as potential candidate for opto-electronic devices. The increase of green band intensity and decrease of UV band at higher Cu concentration confirmed the existence of more defect related states. © 2014 Elsevier B.V. All rights reserved. Source

Krishnamoorthy P.,Rajah Serfoji Government College
Indian Journal of Natural Products and Resources

Carcinogens, 0.06% of p-dimethylaminoazobenzene (p-DAB) with feed and 0.05% phenobarbital (PB) with water were orally administered to rats for 60 days. Powdered endocarps of Ziziphus mauritiana Lam. were extracted with two different solvents, ethanol and ethylacetate. Oral LD 50 of the two extracts were estimated to be 1200.24 mg/kg body weight. Preliminary phytochemical studies of the extracts revealed the presence of triterpenoids, reducing sugars, sugars, alkaloids, phenolics, catechins, flavonoids, saponins, tannins and amino acids. Experimental rats were orally co-fed with the ethanol extract (at two different doses of 300 and 150 mg/kg/bw) and carcinogens. Comparatively, other group was co-fed with ethylacetate extract (at two different doses of 300 and 150mg/kg/b.w) with carcinogens. Antioxidant biochemical studies revealed that ethanol extract was more effective than ethylacetate extract. Histological studies revealed a distinct hepatoprotective effect of Z. mauritiana endocarps (with kernel) at 300 mg/kg body weight of ethanol extract, which sustained the normal architecture of liver cells from p-Dimethtylaminoazobenzene and phenobarbitol induced toxicity, whereas severe damages were evident in the hepatocarcinoma induced rats. Source

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