Raja Rajeswari Dental College and Hospital

Bangalore, India

Raja Rajeswari Dental College and Hospital

Bangalore, India

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PubMed | Narsinhbhai Patel Dental College and Hospital, Rama Dental College and Raja Rajeswari Dental College and Hospital
Type: Journal Article | Journal: Journal of oral and maxillofacial pathology : JOMFP | Year: 2015

Patients with human immunodeficiency virus (HIV) infection have been reported to have parotid swellings of various types such as diffuse infiltrative lymphocytosis syndrome, parotitis, intraparotid lymphadenopathy, benign lymphoepithelial cyst (BLEC), as well as salivary gland neoplasms such as adenoid cystic carcinoma, Kaposi sarcoma and lymphoma. LECs in the parotid gland are uncommon benign entities with increased incidence associated with HIV infection. We are presenting a case of 28-year-old HIV-positive patient with BLECs in the parotid and submandibular glands.


PubMed | Hosmat Superspeciality Hospital, Raja Rajeswari Dental College and Hospital and Institute of Dental science
Type: Journal Article | Journal: Journal of maxillofacial and oral surgery | Year: 2015

The study was done to compare the clinical efficacy of vacuum formed splints and arch bar in treating minimally displaced mandibular fractures.Forty patients were included in two groups. Group 1 was treated with custom made splints and group 2 with conventional arch bar. Patients were recalled on 3rd, 7th, 14th day and on the day of removal of the appliance. Periodontal status, stability of appliance and chair side time were evaluated.The mean chair side time taken by vacuum formed splint was 18.05min and conventional arch bar fixation was 68.25min. 8.3% of patients with vacuum formed splints had poor oral hygiene in comparison with 25% of patients with conventional arch bar. 70% of patients with vacuum formed splints and 60% of the patients with conventional arch bars were comfortable in mastication during treatment.Vacuum formed splints has better advantages over arch bar with respect to chair side time, periodontal health, patients compliance of maintaining oral hygiene, mastication and speech. Vacuum formed splints avoid needle stick injuries. So, they can be used for intermaxillary fixation in minimally displaced mandibular fractures.


Guttikonda V.R.,Mamata Dental College and Hospital | Patil R.,Raja Rajeswari Dental College and Hospital | Kumar G.S.,K S R Institute of Dental science
Journal of Oral and Maxillofacial Pathology | Year: 2014

Aim : To Quantify the DNA single-stranded breaks in the peripheral blood leukocytes (PBLs) of tobacco-habituated individuals with clinically normal mucosa and patients with oral carcinoma.Materials and Methods : Patients who were attending the outpatient department were enrolled in this study. A control group of 30 healthy volunteers included in Group I were selected from various age groups who are not tobacco users in any form. Thirty patients with tobacco habituation but with clinically normal mucosa were included in Group II, while 30 tobacco-habituated patients with oral squamous carcinoma were included in Group III. A biopsy was taken from the representative area and confirmed histologically. Intravenous blood samples were collected from all the groups for evaluation of the extent of DNA damage using ethidium bromide-stained slides under fluorescent microscope. The DNA tail length was calculated by subtracting the diameter from the total length. Twenty-five randomly selected cells per slide were analyzed and mean calculated.Objectives: To evaluate DNA damage levels in PBLs of tobacco-habituated individuals with clinically normal mucosa and patients with oral carcinoma and compare with a control group of healthy volunteers. To evaluate the extent of DNA damage in PBLs using Single Cell Gel Electrophoresis (SCGE) in the above groups.Results : The mean DNA damage levels in patients with tobacco habits were compared with that of the control group and the results were found to be statistically significant. The mean DNA damage level in PBLs between tobacco-habituated patients with normal mucosa and oral cancer patients was found to be statistically significant. The DNA damage in cancer patients was compared with the control group and the results were found to be statistically significant.Conclusion: DNA damage evaluation in PBLs by SCGE technique is a sensitive and reliable indicator of tobacco insult.


PubMed | Mamata Dental College and Hospital, Raja Rajeswari Dental College and Hospital and K S R institute of Dental science
Type: Journal Article | Journal: Journal of oral and maxillofacial pathology : JOMFP | Year: 2014

To Quantify the DNA single-stranded breaks in the peripheral blood leukocytes (PBLs) of tobacco-habituated individuals with clinically normal mucosa and patients with oral carcinoma.To evaluate DNA damage levels in PBLs of tobacco-habituated individuals with clinically normal mucosa and patients with oral carcinoma and compare with a control group of healthy volunteers. To evaluate the extent of DNA damage in PBLs using Single Cell Gel Electrophoresis (SCGE) in the above groups.Patients who were attending the outpatient department were enrolled in this study. A control group of 30 healthy volunteers included in Group I were selected from various age groups who are not tobacco users in any form. Thirty patients with tobacco habituation but with clinically normal mucosa were included in Group II, while 30 tobacco-habituated patients with oral squamous carcinoma were included in Group III. A biopsy was taken from the representative area and confirmed histologically. Intravenous blood samples were collected from all the groups for evaluation of the extent of DNA damage using ethidium bromide-stained slides under fluorescent microscope. The DNA tail length was calculated by subtracting the diameter from the total length. Twenty-five randomly selected cells per slide were analyzed and mean calculated.The mean DNA damage levels in patients with tobacco habits were compared with that of the control group and the results were found to be statistically significant. The mean DNA damage level in PBLs between tobacco-habituated patients with normal mucosa and oral cancer patients was found to be statistically significant. The DNA damage in cancer patients was compared with the control group and the results were found to be statistically significant.DNA damage evaluation in PBLs by SCGE technique is a sensitive and reliable indicator of tobacco insult.


Singh S.,Raja Rajeswari Dental College and Hospital | Shyamala K.,Raja Rajeswari Dental College and Hospital | Girish H.C.,Raja Rajeswari Dental College and Hospital | Murgod S.,Raja Rajeswari Dental College and Hospital | And 2 more authors.
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015

The histopathological diagnosis of Oral leukoplakia (OL) and Oral Submucous Fibrosis (OSMF) is based on the subjective evaluation of morphological anomalies within the lesional tissue. Interpretation of dysplasia varies from one pathologist to another. This subjectivity has turned the interest toward applying computer-assisted morphometry to investigate the cellular and nuclear changes in correlation with the histological behaviour of the lesions. To measure the cellular area (CA) and nuclear area (NA) in OL, OSMF and Normal Oral Mucosa (NOM). 2.To measure the nuclear-cytoplasmic ratio (NCR) in basal layer of OL, OSMF and NOM. 3.To compare and correlate the measurements in OL, OSMF and NOM. 45 cases were included in the study with 20 cases of OL, 20 cases of OSMF and 5 cases of NOM. Basal cells were subjected to Morphometric analysis with image analyser software. The cellular and nuclear area were measured and the nuclear-cytoplasmic ratio was calculated in ten fields. Measurements were tabulated and subjected to statistical analysis. The CA & NA in OL, OSMF are larger compared to NOM with a significant P value of 0.015 and 0.40. The Post Hoc Analysis showed a significant difference of 0.023 between CA of OL and OSMF and a significant value of 0.005 between OSMF and NOM. NCR is increased in OL and OSMF when compared to NOM with a significant P value of 0.009 and Post Hoc analysis revealed significant difference of 0.008 between OL & OSMF and between OSMF and NOM. The significant values obtained in the results suggest that histomorphometry can allow objective information to be acquired and can discriminate between the lesions when the diagnosis is ambiguous.


PubMed | Raja Rajeswari Dental College and Hospital
Type: Journal Article | Journal: Indian journal of dental research : official publication of Indian Society for Dental Research | Year: 2015

The temporomandibular joint is one of the most complex joints of the human body. It consists of the mandibular condyle, glenoid fossa and the articular eminence of the temporal bone. Aplasia of the condyle is usually seen as part of a syndrome otherwise it is rare. We report a case of bilateral condylar aplasia in a 20-year-old male not associated with any syndrome. The patient reported to the department with a chief complaint of the underdeveloped lower jaw. Clinical examination, conventional radiographs, and 3D computer tomography images revealed a complete absence of condyle on the right and left sides.


PubMed | Raja Rajeswari Dental College and Hospital
Type: Journal Article | Journal: Journal of forensic dental sciences | Year: 2015

Dental evidence is a valuable tool in identifying individuals, especially when disasters befall. Reference points in faciomaxillary region such as interpupillary distance, intercanthal distance, interalar distance and bizygomatic width can significantly contribute toward reconstruction of two-dimensional (2D) facial profiles. This study was researched upon to determine the relationship between the maxillary intercanine width and the different reference points of the face.The aim of the following study is to ascertain whether maxillary intercanine width can be used to detect interpupillary distance, intercanthal distance, interalar distance and bizygomatic distance and to evaluate the role of maxillary intercanine width in the 2D reconstruction of the face.The study was carried out by consent and involved 90 subjects-45 males and 45 females who satisfied the inclusion criteria. Subjects were divided into three age groups, i.e. 18-24, 25-28, 29-35. Four parameters were measured- intercanine width, interpupillary distance, intercanthal distance and interalar distance. All the measurements were carried out with a digital Vernier caliper. The bizygomatic width was measured from posterior-anterior view. Two empiricists were assigned for the task. Each test was carried out twice to validate the soundness of the findings and to reduce bias.Analysis of variance and Pearson correlation was established. Regression analysis was performed to predict the study variables by intercanine width.Intercanine width showed a significant relationship with different points. The width varied with age and gender.Inter canine width can be used as a valuable parameter in the reconstruction of face in two dimensional as it shows significant relationship with faciomaxillary reference point such as interpupillary distance, intercanthal distance, interalar distance and bizygomatic width.

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