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Chennai, India

Varghese S.,Sri Ramachandra Dental College | Kailasam V.,Sri Ramachandra Dental College | Padmanabhan S.,Sri Ramachandra Dental College | Vikraman B.,Ragas Dental College | Chithranjan A.,Sri Ramachandra Dental College
Dentomaxillofacial Radiology | Year: 2010

Objectives: The aim of the study was to evaluate the accuracy of linear measurements obtained from reconstructed spiral CT images of human dry skulls in three planes by comparing them with direct skull measurements, and then to compare these with measurements made on photostimulable phosphor cephalograms. Methods: Using a Siemens Somatom Sensation spiral CT scanner (Munich, Germany), CT images of six human dry skulls were imported into imaging software (Mimics 11.02 Materialise, Leuven, Belgium) and the measurements made were compared to the direct measurements made using a digital calliper (500-171, CD-6C, Mitutoyo, Kawasaki, Japan). The measurements were also compared to those made on frontal and lateral cephalograms taken using a digital cephalostat (Planmeca Oy, Helsinki, Finland). The mean of the 15 linear measurements obtained were compared using the paired Student's t-test. Results: CT measurements did not show a significant difference from the direct skull measurements (P < 0.05) in all three planes except for two midsagittal measurements in the anteroposterior plane. Cephalometric measurements were comparable to direct skull measurements for midsagittal measurements in the anteroposterior plane, but showed a significant difference when bilateral measurements were considered. Cephalometric measurements also showed a significant difference in the transverse plane from direct measurements and CT measurements; however, they did not display a significant difference between direct skullmeasurements andCTmeasurements for most parameters in the vertical plane. Conclusion: Linear measurements on the spiral CT were comparable to anatomical measurements and were more reliable than cephalometric measurements. Cephalometric measurements were acceptable for midsagittal measurements in the anteroposterior plane, but showed a significant variation from anatomical and CT measurements in most other parameters. © 2010 The British Institute of Radiology. Source

Lovelina F.D.,Ragas Dental College
Oral health & preventive dentistry | Year: 2012

To assess the oral health status and concordance between monozygotic and dizygotic twin pairs. After obtaining prior consent, a cross-sectional descriptive study was conducted among 9 monozygotic and 21 dizygotic twin pairs who were reared together. Perception towards oral health practices was assessed using a pre-tested questionnaire. The WHO oral health assessment form (1997) was employed to assess the oral health status. Zygosity determination was determined using the medical records, dermatoglyphics and details about chorionicity and number of placental cords. Pearson's correlation was calculated to determine the correlation among the monozygotic and dizygotic twin pairs. The monozygotic twin pairs showed a greater correlation compared to the dizygotic twin pairs in dental caries, periodontal disease and malocclusion. In the present study, monozygotic twin pairs showed a higher correlation rate than the dizygotic twin pairs, suggesting considerable evidence that genes play a significant role in the aetiology of dental caries, periodontal disease and malocclusion. Source

Kalyanasundaram A.P.,Tamil University | Jacob S.M.,Tamil University | Hemalatha R.,Ragas Dental College | Sivakumar M.R.,Tamil University
Journal of the International Association of Physicians in AIDS Care | Year: 2012

As antiretroviral therapy (ART) becomes more available to the HIV-infected population, it is important to determine the prevalence of its long-term complications. In this cross-sectional study, 145 HIV-positive patients on ART, 146 HIV-positive patients not on ART, and 72 HIV-negative individuals visiting the Namakkal District Head Quarters Hospital, Tamil Nadu, India, were recruited from February 2007 to April 2009. Among the patients on ART, the prevalence of lipodystrophy was 60.7%; 22.7% with lipohypertrophy, 51.1% with lipoatrophy, and 22.7% with mixed pattern. The proportion of patients with dyslipidemia was significantly higher in the treatment group when compared to ART-naive and HIV-negative controls (P =.00). Total duration of ART was significantly associated with lipodystrophy (P =.04) and dyslipidemia (P =.01). Also, by logistic regression, abnormal metabolic levels were a risk factor in lipodystrophy (P =.02). This study highlights the need for development of inexpensive and accessible treatments for the reduction of lipodystrophy. © SAGE Publications 2011. Source

Sashikumar R.,Sri Ramachandra University | Kannan R.,Ragas Dental College
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology | Year: 2010

Objective: The aim of this study was to detect salivary glucose levels in diabetic and nondiabetic subjects, to study the relationship between salivary glucose levels and salivary candidal carriage, and to determine if salivary glucose levels could be used as a noninvasive tool to monitor glycemic control in diabetics. Study design: A total of 150 adults, 100 with type 2 diabetes and 50 without diabetes (control subjects), aged 40-60 years, participated in the study. Diabetic status was determined by estimation of random nonfasting plasma glucose levels and glycosylated hemoglobin levels. Both unstimulated and stimulated saliva were collected and investigated for glucose levels and colony-forming units (CFU) of Candida. Salivary glucose levels were measured using the glucose-oxidase method. Results: Salivary glucose levels were significantly higher in diabetics than nondiabetics. There was a significant positive correlation between salivary and plasma glucose levels. Candidal CFUs were significantly higher in diabetic subjects and showed a significant positive correlation with salivary (unstimulated and stimulated) glucose levels. Conclusions: These results show that salivary glucose concentration is a potentially useful noninvasive tool to monitor glycemic control in diabetic patients. Increased salivary glucose is associated with increased prevalence of oral Candida in these subjects. © 2010 Mosby, Inc. All rights reserved. Source

Yugesh K.,Ragas Dental College | Senthil Kumar S.,Sri Ramachandra University
Biomedicine (India) | Year: 2013

Introduction: The peak expiratory flow rate varies according to age, sex, height and body weight. Gravity and various postures also influence the lung function. The authors prefer PEFR values in various postures. Aim: The present study intends to examine the effect of PEFR in different body postures. Materials and Methods: This study was carried out using PEF meter on 50 volunteers having no previous history of lung diseases aged from 15-45 years placing them on various postures like standing, sitting, sitting on chair with back rest vertical, sitting on chair with back rest 45°, supine, prone and side lying. Subjects were asked to perform forceful expiration through the mouth piece of peak flow meter which is been tightly sealed. Procedure was repeated thrice best reading was recorded and analyzed statistically using SPSS software. Results: Lung volume (FEV1 or PEF) differs in various postures against gravity. Maximum lung volume was observed in the standing position (p < 0.01). Decreased lung volume was observed in the prone position. All variables found to be statistically significant. Conclusion: The present study indicates the values of PEFR was more in standing position when compared to other postures. Source

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