Mang'era K.,University of Manitoba |
Ogbomo K.,Radiopharmaceuticals Research Group |
Zriba R.,Radiopharmaceuticals Research Group |
Fitzpatrick J.,Radiopharmaceuticals Research Group |
And 5 more authors.
Journal of Radioanalytical and Nuclear Chemistry
We are developing electron linear accelerator 100Mo(γ,n)99Mo technology as a replacement to nuclear reactor 235U(n,f)99Mo production. We report irradiation of natural molybdenum disks (25 MeV, 10 kW) and 100Mo-enriched disks (35 MeV, 2 kW), their dissolution and the extraction of 99mTc-pertechnetate. Up to 6.2 GBq 99Mo was produced, solvent extraction was performed at >90 % yields of 99mTc, and quality control showed that a product with high radionuclidic and radiochemical purity could be obtained. Irradiated natural molybdenum products showed more impurities (91mNb, 92mNb, 95mNb and 95Nb) than enriched target material. Linear accelerator technology is feasible for production of quality 99Mo/99mTc, particularly when paired with 100Mo-enriched targets. © 2015, Akadémiai Kiadó, Budapest, Hungary. Source