Masmoudi A.D.,University of Sfax |
Ben Ayed N.G.,University of Sfax |
Masmoudi D.S.,University of Sfax |
Abid R.,Radiology Center
Eurasip Journal on Image and Video Processing | Year: 2013
Mammogram tissue density has been found to be a strong indicator for breast cancer risk. Efforts in computer vision of breast parenchymal pattern have been made in order to improve the diagnostic accuracy by radiologists. Motivated by recent results in mammogram tissue density classification, a novel methodology for automatic American College of Radiology Breast Imaging Reporting and Data System classification using local binary pattern variance descriptor is presented in this article. The proposed approach characterizes the local density in different types of breast tissue patterns information into the LBP histogram. The performance of macro-calcification detection methods is developed using FARABI database. Performance results are given in terms of receiver operating characteristic. The area under curve of the corresponding approach has been found to be 79%. © 2013 Damak Masmoudi et al.; licensee Springer.
Jukovic M.,Radiology Center |
Till V.,Radiology Center
Medicinski Glasnik | Year: 2012
Chronic subdural hematoma is usually caused by minor head trauma and occurs frequently with older people. Predisposing factors include alcohol abuse, epilepsy and coagulopathy. This report presents a 65-year old woman who had a large, mixed density, left sided compressive chronic subdural hematoma diagnosed by computed tomography. She also displayed a moderate neurological deficit on admission, confusion and behavioral disorder with Glasgow Coma Score 10. The computed tomography and neurological parameters indicated the necessity of surgery. A difficult general condition and coagulation factor disorder in this patient were determinative for the decision for non-operative treatment. It is very rare that a large chronic subdural hematoma is resolved completely spontaneously, but in our case conservative treatment gave an excellent result.
Reiche W.,Institute of Radiology |
Schuchardt V.,Clinic for Neurology |
Hagen T.,Radiology Center |
Il'yasov K.A.,University Hospital Freiburg |
And 2 more authors.
Clinical Neurology and Neurosurgery | Year: 2010
Objective: To evaluate the contribution of DWI and DTI to the differential diagnosis of cerebral ring enhancing lesions by describing DWI and ADC (apparent diffusion coefficient) findings and measuring the two DTI parameters mean diffusivity (MD) and fractional anisotropy (FA). Materials and methods: A total of 17 patients presenting with 26 rim enhancing cysts were investigated with DWI and DTI. Parameter maps of the DTI metrics MD and FA were calculated and quantified using regions of interest (ROIs). Results: Five patients suffered from abscesses with a total of 10 cysts, 9 from glioblastomas with 10 cysts, and 3 from metastases with 6 cysts. All abscess cavities showed hyperintense DWI signal intensity compared to normal appearing white matter (NAWM), low ADC, low MD and high FA. Eight out of 10 glioblastoma cysts and all 6 metastatic cysts revealed hypointensity on DWI, high ADC, high MD and low FA (p < 0.0001 compared to abscess group). DWI findings of 2/10 glioblastoma cysts overlapped with those of abscesses showing hyperintensity on DWI, low ADC and low MD and hence mimicked abscesses. FA of these 2 glioblastoma cysts was significantly lower than in abscess cavities (p = 0.032). Conclusion: The findings of reduced diffusion compared to NAWM and increased FA within a ring enhancing cyst strongly indicate a cerebral abscess. In contrast, the majority of neoplastic cysts revealed high diffusion and low FA. Reduced diffusion is also found in a very small number of tumour cysts, but in these low FA refers to a non-infectious origin and thus helps distinguishing from infectious abscess. © 2009 Elsevier B.V. All rights reserved.
Guglielmo F.F.,Thomas Jefferson University |
Mitchell D.G.,Thomas Jefferson University |
O'Kane P.L.,Thomas Jefferson University |
Deshmukh S.P.,Thomas Jefferson University |
And 5 more authors.
Abdominal Imaging | Year: 2015
Purpose: The purpose of this study was to evaluate whether affected bowel in Crohn’s disease patients can be identified by observing decreased peristalsis (frozen bowel sign) using cine balanced steady-state free precession (cine BSSFP) images. Materials and methods: 5 radiologists independently reviewed cine BSSFP sequences from randomized MR Enterography (MRE) exams for 30 normal and 30 Crohn’s disease patients, graded overall small bowel peristalsis from slowest to fastest, and graded peristalsis for the most abnormal small bowel segment. Sensitivity and specificity of the frozen bowel sign for diagnosing Crohn’s disease were calculated. T tests of the peristalsis difference between abnormal segments and overall small bowel were conducted. Results: For 5 readers, the sensitivity and specificity of cine BSSFP of the frozen bowel sign for diagnosing Crohn’s disease ranged from 70% to 100% and 87% to 100%, respectively. There were significant differences in peristalsis between abnormal small bowel segments and the overall small bowel for Crohn’s patients, but not in the overall small bowel between normal-MRE patients and Crohn’s disease patients. Conclusion: Abnormal Crohn’s small bowel segments have significantly decreased peristalsis compared to normal small bowel, which can be identified using cine BSSFP sequences as the frozen bowel sign. © 2014, Springer Science+Business Media New York.
Liik M.,University of Tartu |
Paris M.,Radiology Center |
Vahter L.,West Tallinn Central Hospital |
Gross-Paju K.,West Tallinn Central Hospital |
Haldre S.,University of Tartu
BMC Neurology | Year: 2013
Background: Purpose of the study was to investigate alterations in midbrain serotonin transporter (SERT) binding in patients with epilepsy and symptoms of depression compared to patients with epilepsy with no symptoms of depression.Methods: We studied 12 patients with epilepsy (7 patients had focal and 5 had generalized epilepsy syndromes). The presence of self-reported symptoms of depression was assessed using Beck Depression Inventory (BDI) and the Emotional State Questionnaire (EST-Q). The binding potential of the SERT was assessed by performing brain single photon emission tomography (SPET) using the SERT radioligand 2-((2-((dimethylamino)methyl)phenyl)thio)-5-(123)iodophenylamine (123I-ADAM).Results: Seven patients had BDI and EST-Q subscale scores greater than 11 points, which was interpreted as the presence of symptoms of depression. We found that 123I-ADAM binding was not significantly different between patients with epilepsy with and without symptoms of depression. In addition, 123I-ADAM binding did not show a significant correlation to either BDI or EST-Q depression subscale scores and did not differ between patients with focal vs. generalized epilepsy.Conclusion: The results of our study failed to demonstrate alterations of SERT binding properties in patients with epilepsy with or without symptoms of depression. © 2013 Liik et al.; licensee BioMed Central Ltd.
Sillat T.,University of Helsinki |
Sillat T.,Radiology Center |
Barreto G.,University of Helsinki |
Clarijs P.,University of Helsinki |
And 11 more authors.
Acta Orthopaedica | Year: 2013
Background and purpose Degenerating cartilage releases potential danger signals that react with Toll-like receptor (TLR) type danger receptors. We investigated the presence and regulation of TLR1, TLR2, and TLR9 in human chondrocytes. Methods We studied TLR1, TLR2, TLR4, and TLR9 mRNA (qRT-PCR) and receptor proteins (by immunostaining) in primary mature healthy chondrocytes, developing chondrocytes, and degenerated chondrocytes in osteoarthritis (OA) tissue sections of different OARSI grades. Effects of a danger signal and of a pro-inflammatory cytokine on TLRs were also studied. Results In primary 2D-chondrocytes, TLR1 and TLR2 were strongly expressed. Stimulation of 2D and 3D chondrocytes with a TLR1/2-specific danger signal increased expression of TLR1 mRNA 1.3- to 1.8-fold, TLR2 mRNA 2.6- to 2.8-fold, and TNF-α mRNA 4.5- to 9-fold. On the other hand, TNF-α increased TLR1 mRNA] expression 16-fold, TLR2 mRNA expression 143- to 201-fold, and TNF-α mRNA expression 131- to 265-fold. TLR4 and TLR9 mRNA expression was not upregulated. There was a correlation between worsening of OA and increased TLR immunostaining in the superficial and middle cartilage zones, while chondrocytes assumed a CD166 × progenitor phenotype. Correspondingly, TLR expression was high soon after differentiation of mesenchymal stem cells to chondrocytes. With maturation, it declined (TLR2, TLR9). Interpretation Mature chondrocytes express TLR1 and TLR2 and may react to cartilage matrix/chondrocyte-derived danger signals or degradation products. This leads to synthesis of pro-inflammatory cytokines, which stimulate further TLR and cytokine expression, establishing a vicious circle. This suggests that OA can act as an autoinflammatory disease and links the old mechanical wear-and-tear concept with modern biochemical views of OA. These findings suggest that the chondrocyte itself is the earliest and most important inflammatory cell in OA. © Nordic Orthopaedic Federation.
Waris E.,University of Helsinki |
Mattila S.,University of Helsinki |
Sillat T.,University of Helsinki |
Sillat T.,Radiology Center |
Karjalainen T.,Central Hospital of Central Finland
Journal of Hand Surgery | Year: 2016
Purpose To evaluate the outcomes of extension block pinning used to treat unstable dorsal fracture dislocations of the proximal interphalangeal (PIP) joint. The factors affecting the functional outcome were analyzed. Methods A series of 53 patients with 55 dorsal fracture dislocations of the PIP joint treated with closed reduction and extension block pinning were retrospectively reviewed. Additional percutaneous intramedullary fracture reduction (16 cases) or open fracture reduction (4 cases) had been performed. The radiological and clinical evaluations were included. Results At a mean follow-up of 5.2 years (range, 1.0-10.6 years), 39 patients with 41 injured fingers were evaluated. The fracture fragments involved 30% to 69% (mean, 50%) of the articular surface of the middle phalanx. The mean range of motion was 80° (range, 35° to 115°) at the PIP joint with a mean extension loss of 6° (range, 0° to 50°) excluding 2 joints that were salvaged with arthrodesis. The mean range of motion of the distal interphalangeal joint was 68° (range, 5° to 90°). The mean visual analog scale for digit pain was 1.5/10. The reduction of the joint was achieved intraoperatively in all cases. However, after the hardware removal, recurrent minimal subluxation was observed in 12 cases (29%). Recurrent subluxation was associated with increased residual pain. The length of follow-up time had a positive correlation, whereas the patient age had a negative correlation with the range of motion of the injured PIP joint. Conclusions The extension block pinning technique is a simple and valuable technique for treating unstable dorsal PIP fracture-dislocation injuries producing satisfactory long-term results. Type of study/level of evidence Therapeutic IV. © 2016 American Society for Surgery of the Hand.
PubMed | Children Hospital of Toulouse and Radiology Center
Type: Journal Article | Journal: Surgical and radiologic anatomy : SRA | Year: 2016
Congenital diaphragmatic hernia is a rare congenital malformation, as well as kidney ectopia. Among kidney ectopias, the intrathoracic one is the rarest. Those malformations concern more frequently boys, and affected more the left than the right side. Their association is poorly reported in the literature. We report the rare case of an early sonographic prenatal diagnosis of intrathoracic kidney at 22weeks of gestation in a female fetus, completed on the follow-up by the diagnosis of an associated diaphragmatic hernia at 33weeks of gestation. If chest mass is diagnosed prenatally or in neonate, ITK should be considered in a differential diagnosis, all the more if the ipsilateral renal fossa is empty. An associated DH should be searched if ITK is confirmed. Isolated ITK usually requires no specific treatment, in contrast with ITK associated with DH.
PubMed | Shiraz University of Medical Sciences and Radiology Center
Type: | Journal: Radiology research and practice | Year: 2015
Background. Usefulness of ultrasound (US) in detection of intrabony lesions has been showed. A cortical bone perforation or a very thin and intact cortical bone is prerequisite for this purpose. Objective. The current in vitro study was aimed at measuring the cut-off thickness of the overlying cortical bone which allows ultrasonic assessment of bony defects. Materials and Methods. 20 bovine scapula blocks were obtained. Samples were numbered from 1 to 20. In each sample, 5 artificial lesions were made. The lesions were made in order to increase the overlying bone thickness, from 0.1mm in the first sample to 2mm in the last one (with 0.1mm interval). After that, the samples underwent ultrasound examinations by two practicing radiologists. Results. All five lesions in samples numbered 1 to 11 were detected as hypoechoic area. Cortical bone thickness more than 1.1 mm resulted in a failure in the detection of central lesions. Conclusion. We can conclude that neither bony perforation nor very thin cortical bones are needed to consider US to be an effective imaging technique in the evaluation of bony lesion.
News Article | November 7, 2016
NEW YORK, Nov. 7, 2016 /PRNewswire/ -- LabFinder.com, a convenient online platform for patients to schedule their laboratory and radiology tests and access test results, has announced Madison Avenue Radiology Center is now a subscriber to the service, vastly expanding LabFinder's...