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Kala Z.,Chirurgicka klinika FN Brno a LF MU | Kysela P.,Chirurgicka klinika FN Brno a LF MU | Ostrizkova L.,Interni hematoonkologicka klinika FN Brno a LF MU | Kiss I.,Klinika komplexni onkologicke pece | And 2 more authors.
Onkologie | Year: 2011

Background: The incidence of colorectal carcinoma has been increasing. Only a multimodal treatment provides the best results. Surgical R0 resection of all tumour sites is the goal of all treatment regimes. Material and methods: A survey on the literature and our experiences has been conducted. Results: Surgical treatment comprises endoscopic submucosal dissection, transanal endoscopic microsurgery, laparoscopy, open surgery and cytoreduction surgery with the hyperthermic intraperitoneal chemotherapy. The news is the total mesocolic excision that similarly to the total mesorectal excision provides fewer local relapses and higher long-term survival. Conclusion: Similarly to anti-tumoral medical therapy, the surgery has been developing as well. It is necessary to enrol the patients into suitable databases to state the proper position of all surgical methods in the multimodal treatment algorithm.


Smajerova M.,Radiologicka Klinika FN Brno a LF MU | Petrasova H.,Radiologicka Klinika FN Brno a LF MU | Andrasina T.,Radiologicka Klinika FN Brno a LF MU | Valek V.,Radiologicka Klinika FN Brno a LF MU
Ceska Radiologie | Year: 2015

Aim: The aim was to find out whether contrast-enhanced ultrasonography (CEUS) is a cost-effective method for the first line evaluation of focal liver lesions (FLL) compared to CT and MRI. Method: The retrospective study included 254 patients, with 538 FLL, examined using CEUS in 2012. Where CEUS results were not conclusive, CT or MRI was performed. Some patients with malignant findings on CEUS had additional CT for staging. We calculated the cost of this strategy. Then we calculated the cost if all of the patients had been examined by CT or MRI after initial native ultrasound. Results: The costs for evaluation of these lesions by CEUS (+ additional examinations) were 888 763,01 Kč for the year 2012. If we had used CT or MRI it would have been 929 614,60 Kč and 4 317 011,94 Kč, respectively. CEUS was 40 851,59 Kč (4.39%) cheaper compared to CT and 3 428 248,93 Kč (79.41 %) cheaper compared to MRI. Conclusion: Costs for evaluation of FLL by CEUS and CT were similar. CEUS is a much more cost-effective method compared to MRI.


Slaisova R.,Radiologicka klinika FN Brno a LF MU | Benda K.,Radiologicka klinika FN Brno a LF MU | Szturz P.,Interni hematologicka a onkologicka | Petrasova H.,Radiologicka klinika FN Brno a LF MU | Mechl M.,Radiologicka klinika FN Brno a LF MU
Onkologie | Year: 2012

Many pathological processes can affect lymph nodes including specific and nonspecific inflammation, further a number of benign reactive changes and primary and secondary tumour processes. Imaging and evaluation of lymph nodes as benign or potentially malignant is particularly important mainly in case of cancer staging and for patients with incidental lymphadenopathy. The work presents an overview of imaging methods used for the diagnosis of lymphadenopathy. We mention modern imaging method of contrast-enhanced ultrasound that requires a microbubble contrast agent for evaluation of nodal perfusion. The method is supplied with pictorial documentation of ultrasound findings. Other methods are also listed-computed tomography and magnetic resonance imaging, including their limitations and currently rarely used conventional lymphography.

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